
Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase(95 products)
- CDK(501 products)
- Cell Cycle Arrest(4 products)
- Chk(42 products)
- DYRK(48 products)
- Dynamin(23 products)
- Ferroptosis(215 products)
- HSP(169 products)
- Integrin(224 products)
- Kinesin(66 products)
- LIM Kinase(19 products)
- Microtubule Associated(262 products)
- PKC(102 products)
- PLK(28 products)
- ROCK(69 products)
- Rho(2 products)
- Wee1(15 products)
- c-Myc(69 products)
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Found 3485 products of "Cell Cycle/Checkpoint"
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Aurora/LIM kinase-IN-1
<p>Aurora/LIM kinase-IN-1 (Compound F114) is a dual inhibitor targeting aurora and lim kinases, potentially useful in GBM cancer treatment efforts.</p>Formula:C16H20N6OColor and Shape:SolidMolecular weight:312.37Zeltociclib
CAS:<p>Zeltociclib is an inhibitor of cyclin-dependent kinases (CDKs) with anti-tumor properties.</p>Formula:C18H20F3N4O2PColor and Shape:SolidMolecular weight:412.346Xanthosine-5'-Triphosphate trisodium
CAS:<p>Xanthosine-5'-Triphosphate (5'-XTP) trisodium is a nucleotide formed through the deamination of purine bases. It serves as a substrate for inosine triphosphate pyrophosphatase (ITPase).</p>Formula:C10H12N4Na3O15P3Color and Shape:SolidMolecular weight:590.111Dyrk1A/α-synuclein-IN-1
<p>Dyrk1A/α-synuclein-IN-1 (Compound b1) is a dual inhibitor of Dyrk1A (IC50: 177 nM) and α-synuclein aggregation (IC50: 10.5 μM).</p>Formula:C20H21N5O3SColor and Shape:SolidMolecular weight:411.482-CEES
CAS:<p>2-CEES is a mustard gas analogue that only forms DNA monoadducts. It induces centromere amplification in both human and mouse cells and can lead to chromosome instability.</p>Formula:C4H9ClSColor and Shape:SolidMolecular weight:124.63211-Oxahomoaminopterin
CAS:<p>11-Oxahomoaminopterin exhibits antifolate activity against two folate-requiring microorganisms and inhibited Lactobacillus casei DHFR.</p>Formula:C20H21N7O6Purity:98%Color and Shape:SolidMolecular weight:455.42L 734217
CAS:<p>L 734217 is an antagonist of the fibrinogen receptor.</p>Formula:C18H31N3O4Purity:98%Color and Shape:SolidMolecular weight:353.46GR 122222X
CAS:<p>GR 122222X is an inhibitor of topoisomerase II.</p>Formula:C26H35N5O11SPurity:98%Color and Shape:SolidMolecular weight:625.65DIDS
CAS:<p>DIDS inhibits anion exchangers reversibly then irreversibly and blocks RAD51.</p>Formula:C16H10N2O6S4Purity:98%Color and Shape:SolidMolecular weight:454.52DDO-6079
CAS:<p>DDO-6079 is an efficient CDC37 inhibitor. It suppresses the HSP90-CDC37 and CDC37-CDK4/6 chaperone complexes by binding to an allosteric site on CDC37. Additionally, DDO-6079 reduces the thermal stability of CDK6.</p>Formula:C18H13ClN2O3Color and Shape:SolidMolecular weight:340.76Bersiporocin
CAS:<p>Bersiporocin is a novel prolyl-tRNA synthetase (PRS) inhibitor that exerts antifibrotic effects through downregulation of collagen synthesis in IPF.</p>Formula:C15H19Cl2N3OPurity:98.88% - 99.79%Color and Shape:SolidMolecular weight:328.24Z4P
CAS:<p>Z4P, an IRE1 inhibitor with blood-brain barrier permeability (BBB), inhibited glioblastoma growth and recurrence in combination with Temozolomide.</p>Formula:C19H24N2O2Purity:98.99%Color and Shape:SolidMolecular weight:312.41WEE1-IN-10
CAS:<p>WEE1-IN-10 is a Wee1 kinase inhibitor that inhibits the growth of LOVO cells, such as pancreatic cancer, malignant melanoma, and malignant glioma.</p>Formula:C28H30Cl2N8OPurity:98.18%Color and Shape:SolidMolecular weight:565.5BAY-364
CAS:<p>BAY-364 (BAY-299N) functions as an inhibitor targeting the second bromine domain in TAF1, demonstrating inhibitory effects on TAF1 in Kasumi-1 cells, CD34+</p>Formula:C23H19N3O4Color and Shape:SolidMolecular weight:401.41Dyrk1A-IN-1
<p>Dyrk1A-IN-1 is a triple inhibitor of Dyrk1A kinase activity, aggregation of tau and α-syn oligomers, with an IC50 value of 119 nM for Dyrk1A kinase.</p>Formula:C23H20N4O3SColor and Shape:SolidMolecular weight:432.49APE1-IN-3
CAS:<p>APE1-IN-3 (Compound 1), an APE1 inhibitor, is utilized in cancer research.</p>Formula:C17H16O4Color and Shape:SolidMolecular weight:284.31Cdc7-IN-8
CAS:<p>Cdc7-IN-8, inhibits Cdc7 kinase, key in DNA replication, and is promising for cancer research. (WO2021032170A1)</p>Formula:C19H21N5O2Color and Shape:SolidMolecular weight:351.40Dencatistat
CAS:<p>Dencatistat is a highly selective and oral cytidine triphosphate synthase 1 CTPS1 inhibitor specific.CTPS1-IN-2 for B-cell, T-cell lymphomas and solid tumors.</p>Formula:C24H27N7O5SPurity:98.85%Color and Shape:SolidMolecular weight:525.58HPH-15
CAS:<p>HPH-15 is an anti-cell migration compound that inhibits cell movement by binding to hnRNP U or suppressing TGF-β. Additionally, it prevents epithelial-to-mesenchymal transition (EMT). HPH-15 holds potential for research in areas such as anti-tumor metastasis and anti-fibrosis.</p>Formula:C19H31N3S4Color and Shape:SolidMolecular weight:429.73CDK5-IN-2
CAS:<p>CDK5-IN-2 (compound 15) is a highly selective CDK5 inhibitor that acts on CDK5/p25 (IC50: 0.2 nM) and CDK2/CycA (IC50: 23 nM).</p>Formula:C29H28FN5OColor and Shape:SolidMolecular weight:481.56

