Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase(115 products)
- CDK(546 products)
- Cell Cycle Arrest(5 products)
- Chk(48 products)
- DYRK(47 products)
- Dynamin(27 products)
- Ferroptosis(227 products)
- HSP(180 products)
- Integrin(269 products)
- Kinesin(87 products)
- LIM Kinase(20 products)
- Microtubule Associated(274 products)
- PKC(126 products)
- PLK(25 products)
- ROCK(62 products)
- Rho(6 products)
- Wee1(14 products)
- c-Myc(76 products)
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Found 3906 products of "Cell Cycle/Checkpoint"
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KWR137
KWR137 is a WRN degrader with an IC50 of 8 nM. It exhibits significant antiproliferative activity against MSI-H cells, with a GI50 of 509 nM for SW48 cells and 824 μM for HCT116. Additionally, KWR137 demonstrates antitumor growth effects in xenograft mouse models. This compound is applicable for cancer research.Formula:C33H31ClF3N9O4Color and Shape:SolidMolecular weight:710.105CDK9 inhibitor HH1
CAS:CDK9 inhibitor HH1 (8019-9719) is an inhibitor of the human CDK2-cyclin A2 complex with an IC50 value of 2 μM.
Formula:C13H15N3OSPurity:99.92%Color and Shape:SolidMolecular weight:261.34Remdesivir nucleoside monophosphate
CAS:Remdesivir metabolite, antiviral nucleoside analog, effective against SARS-CoV and MERS-CoV.Formula:C12H14N5O7PColor and Shape:SolidMolecular weight:371.24GSK299423
CAS:GSK299423: Antibiotic possibly effective against bacteria with New Delhi metal-β-lactamase, targeting topoisomerases.Formula:C25H27N5O2SPurity:97.34%Color and Shape:SolidMolecular weight:461.58N3,5-Dimethyl-2'-O-(2-methoxyethyl) uridine
N3,5-Dimethyl-2’-O-(2-methoxyethyl) uridine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies.Formula:C14H22N2O7Color and Shape:SolidMolecular weight:330.335-O-TBDMS-N4-Benzoyl-2-deoxycytidine
CAS:5-O-TBDMS-N4-Benzoyl-2-deoxycytidine is a modified nucleoside utilized in the synthesis of deoxyribonucleic acid (DNA) or nucleic acid.Formula:C22H31N3O5SiColor and Shape:SolidMolecular weight:445.58αVβ8-IN-1
CAS:αVβ8-IN-1 is an αVβ8 integrin inhibitor that suppresses the growth of multiple tumour cell lines (EMT6, CT26, KPC, TKCC-10).Formula:C25H32ClN5O4Color and Shape:SolidMolecular weight:502.015'(R)-C-Methyl-5-fluorouridine
5’(R)-C-Methyl-5-fluorouridine, a uridine analogue, possesses potential antiepileptic properties.Formula:C10H13FN2O6Color and Shape:SolidMolecular weight:276.22FF-10502
CAS:FF-10502, a pyrimidine analog of Gemcitabine, inhibits DNA polymerases α/β, targeting dormant cancer cells.Formula:C9H12FN3O3SColor and Shape:SolidMolecular weight:261.27CBR-2092
CAS:CBR-2092 is a DNA-directed RNA polymerase and DNA topoisomerase inhibitor.Formula:C65H81FN6O15Color and Shape:SolidMolecular weight:1205.3882'-(2-Nitrobenzyl)-ATP trisodium
2'-(2-Nitrobenzyl)-ATP trisodium is an rATP analogue that acts as a transcription terminator. It inhibits T7 RNA polymerase from continuing RNA chain extension.Formula:C17H18N6Na3O15P3Color and Shape:SolidMolecular weight:707.97361CDK1-IN-2
CAS:CDK1-IN-2 (cdk1 inhibitor 2) is a CDK1 inhibitor with IC50 of 5.8 μM.Formula:C17H11ClN2OPurity:98.53%Color and Shape:SoildMolecular weight:294.73Ref: TM-T64373
1mg50.00€1mL*10mM (DMSO)103.00€5mg107.00€10mg170.00€25mg354.00€50mg567.00€100mg810.00€500mg1,644.00€PROTAC CDK9 degrader 4
CAS:PROTAC CDK9 degrader 4 is a CDK9 degrader that targets transcriptional regulation and has potential anticancer activity.Formula:C43H56N10O5Color and Shape:SolidMolecular weight:792.975'-O-DMT-N2-DMF-dG
CAS:5'-O-DMT-2'-O-TBDMS-rI, a modified nucleoside, finds application in deoxyribonucleic acid (DNA) or nucleic acid synthesis.Formula:C34H36N6O6Color and Shape:SolidMolecular weight:624.698Antibacterial agent 144
Antibacterial Agent 144 (compound 8e) exhibits superior efficacy against multi-resistant Staphylococcus aureus compared to Chloromycin and Amoxicillin.Formula:C26H23N7O3Color and Shape:SolidMolecular weight:481.51Rifalazil
CAS:Rifalazil (KRM-1648) is a benzophenazine antibiotic with antibacterial activity, useful for research on chlamydia infections.Formula:C51H64N4O13Purity:98%Color and Shape:SolidMolecular weight:941.07AB-3PRGD2
CAS:AB-3PRGD2 is a radiolabeled agent that targets integrin αvβ3. It enhances tumor uptake and prolongs retention time in tumors, significantly improving the inhibition of tumor growth. AB-3PRGD2 also remodels the tumor immune microenvironment by upregulating PD-L1 expression and increasing tumor-infiltrating CD8+ T cells.
Formula:C137H215IN30O45SColor and Shape:SolidMolecular weight:3161.325'-O-TBDMS-dG
CAS:5’-O-TBDMS-dG is a modified nucleoside. 5’-O-DMT-2’-O-TBDMS-rI can be used in the synthesis of deoxyribonucleic acid or nucleic acid.Formula:C16H27N5O4SiColor and Shape:SolidMolecular weight:381.50Emicoron
CAS:Importazole is an inhibitor of the transport receptor importin-β. It specifically inhibits importin-β likely by altering its interaction with RanGTP.Formula:C52H58N6O4Purity:98%Color and Shape:SolidMolecular weight:831.05Cytidine 5'-diphosphate trisodium salt
CAS:CDP, a trisodium salt, helps synthesize DNA/RNA by aiding phosphoryl transfer from ATP to CMP via UMPK.Formula:C9H15N3Na3O11P2Purity:99.55%Color and Shape:White Crystalline PowderMolecular weight:472.15
