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Cell Cycle/Checkpoint

Cell Cycle/Checkpoint

Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.

Subcategories of "Cell Cycle/Checkpoint"

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Found 3477 products of "Cell Cycle/Checkpoint"

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  • CymitQuimica logo
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    FRα-targeting peptide C7 TFA

    <p>FRα-targeting peptide C7 TFA is a selective peptide ligand for the folate receptor alpha (FRα) that specifically binds to FRα-expressing cells and has tumor-targeting capabilities in vivo. It is applicable in research related to tumor diagnosis and therapy.</p>
    Color and Shape:Odour Solid

    Ref: TM-TP3238

  • CBR-2092
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    CBR-2092

    CAS:
    <p>CBR-2092 is a DNA-directed RNA polymerase and DNA topoisomerase inhibitor.</p>
    Formula:C65H81FN6O15
    Color and Shape:Solid
    Molecular weight:1205.388

    Ref: TM-T26963

  • SNX7
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    SNX7

    CAS:
    <p>SNX7 (WAY-323879) inhibits CDKI pathway; useful for studying aging and related diseases.</p>
    Formula:C15H14N2O
    Purity:99.05%
    Color and Shape:Solid
    Molecular weight:238.28

    Ref: TM-T77613

  • LY243246
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    LY243246

    CAS:
    <p>LY249543, the S-isomer of lometrexol, is an inhibitor of Methylenetetrahydrofolate Dehydrogenase/Cycl.</p>
    Formula:C21H25N5O6
    Color and Shape:Solid
    Molecular weight:443.45

    Ref: TM-T27933

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    HDAC-IN-85

    <p>HDAC-IN-85 (Compound 1) is an HDAC inhibitor capable of crossing the blood-brain barrier. It exhibits inhibitory effects on brain tumor cell lines and can induce acetylation, resulting in DNA double-strand breaks and promoting RAD51 ubiquitination, which disrupts the DNA repair process. HDAC-IN-85 is applicable in studies of glioblastoma.</p>
    Formula:C24H27FN4O5
    Color and Shape:Solid
    Molecular weight:470.49

    Ref: TM-T205411

  • Nusinersen
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    Nusinersen

    CAS:
    <p>Nusinersen (nusinersen) is a antisense oligonucleotide (ASO) for the treatment of pediatric and adult spinal muscular atrophy (SMA) and increases SMN proteinss.</p>
    Purity:98.62%
    Color and Shape:Solid

    Ref: TM-T38656

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    Catumaxomab

    CAS:
    <p>Catumaxomab is a rat-mouse hybrid lgG2 monoclonal and bispecific antibody that binds to the antigens CD3 and EpCAM for malignant ascites in cancer patients.</p>
    Purity:95%
    Color and Shape:Liquid

    Ref: TM-T78307

  • JAMM protein inhibitor 2 
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    JAMM protein inhibitor 2 

    CAS:
    <p>JAMM inhibitor 2 targets thrombin, Rpn11, MMP2 with IC50s 10, 46, 89 μM, aids cancer research.</p>
    Formula:C21H26N2O2
    Purity:98.57%
    Color and Shape:Solid
    Molecular weight:338.44

    Ref: TM-T9892

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    PROTAC CDK9 degrader-8

    <p>PROTAC CDK9 Degrader-8 (Compound 21) is a potent degrader of CDK9 with an IC50 of 0.01 μM, utilized in cancer research [1].</p>
    Formula:C44H52Cl2N10O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:903.85

    Ref: TM-T78928

  • UCK2 Inhibitor-3
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    UCK2 Inhibitor-3

    CAS:
    <p>UCK2 Inhibitor-3 blocks UCK2 (IC50: 16.6μM) and DNA polymerases eta/kappa (IC50s: 56μM/16μM), aiding uridine salvage in certain cells.</p>
    Formula:C19H13BrFN5O2S
    Color and Shape:Solid
    Molecular weight:474.31

    Ref: TM-T72696

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    Antibacterial agent 144

    <p>Antibacterial Agent 144 (compound 8e) exhibits superior efficacy against multi-resistant Staphylococcus aureus compared to Chloromycin and Amoxicillin.</p>
    Formula:C26H23N7O3
    Color and Shape:Solid
    Molecular weight:481.51

    Ref: TM-T79282

  • R-1479
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    R-1479

    CAS:
    <p>R-1479 (4'-Azidocytidine) is an RdRp inhibitor with an IC50 value of 1.28 μM for HCV RNA replication in the HCV subgenomic replicon system.</p>
    Formula:C9H12N6O5
    Purity:98.11% - 99.95%
    Color and Shape:Solid
    Molecular weight:284.23

    Ref: TM-TQ0162

  • FF-10502
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    FF-10502

    CAS:
    <p>FF-10502, a pyrimidine analog of Gemcitabine, inhibits DNA polymerases α/β, targeting dormant cancer cells.</p>
    Formula:C9H12FN3O3S
    Color and Shape:Solid
    Molecular weight:261.27

    Ref: TM-T39290

  • Guanosine 5'-triphosphate trisodium salt hydrate
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    Guanosine 5'-triphosphate trisodium salt hydrate

    CAS:
    <p>5'-GTP trisodium salt hydrate activates G proteins and is a precursor for DNA/RNA synthesis.</p>
    Formula:C10H18N5NaO15P3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:564.185

    Ref: TM-T10178

  • Ac-MRGDH-NH2
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    Ac-MRGDH-NH2

    <p>Ac-MRGDH-NH2 is a pentapeptide containing the RGD sequence. It is utilized in the synthesis of the diastereomeric prodrugs Λ- and Δ-[Ru(Ph2phen)2(κS,κN-(Ac-MRGDH-NH2))]Cl2. In these prodrugs, Ac-MRGDH-NH2 serves as a photolabile protecting group for the cytotoxic diruthenium aqua complexes [Ru(Ph2phen)2(OH2)2]2+, offering integrin targeting and photoactivation properties. Consequently, Ac-MRGDH-NH2 can be applied in studies exploring tumor-targeted photoactivatable chemotherapy.</p>
    Formula:C25H41N11O8S
    Color and Shape:Solid
    Molecular weight:655.727

    Ref: TM-TP3057

  • 2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)
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    2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)

    CAS:
    <p>dGMP is a substrate for DNA synthesis, phosphorylated to dGDP and dGTP, and linked to mitochondrial DNA depletion syndrome in humans.</p>
    Formula:C10H14N5Na2O8P
    Color and Shape:Solid
    Molecular weight:409.202

    Ref: TM-T35652

  • SMS 121
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    SMS 121

    CAS:
    <p>SMS 121 is a novel CD36 inhibitor that impairs fatty acid uptake and cell viability in acute myeloid leukaemia (AML) cells.</p>
    Formula:C20H21NO5
    Purity:98.29%
    Color and Shape:Soild
    Molecular weight:355.38

    Ref: TM-T205876

  • 6-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine
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    6-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine

    CAS:
    <p>6-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine, a pyrimidine nucleoside analog, exhibits a broad spectrum of biochemical and</p>
    Formula:C11H15N5O4
    Color and Shape:Solid
    Molecular weight:281.27

    Ref: TM-T75185

  • RNA splicing modulator 1
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    RNA splicing modulator 1

    CAS:
    <p>RNA Splicing Modulator 1 (Compound 233) is a modulator of RNA splicing, exhibiting an AC50 value of less than 100 nM [1].</p>
    Formula:C19H20N6OS
    Color and Shape:Solid
    Molecular weight:380.47

    Ref: TM-T74884

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    2'-Fluoro-2'-deoxy-arabinoadenosine 5'-triphosphate triethylamine

    <p>2’-Fluoro-2’-deoxy-arabinoadenosine 5’-triphosphate (triethylamine) is a purine nucleoside analog with significant antitumor properties, particularly effective</p>
    Formula:C34H75FN9O12P3
    Color and Shape:Solid
    Molecular weight:913.93

    Ref: TM-T75207