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Cell Cycle/Checkpoint

Cell Cycle/Checkpoint

Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.

Subcategories of "Cell Cycle/Checkpoint"

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Found 3480 products of "Cell Cycle/Checkpoint"

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  • CymitQuimica logo
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    Antibacterial agent 271

    <p>Antibacterialagent 271 is an antimicrobial compound that significantly inhibits Escherichia coli, with a minimum inhibitory concentration (MIC) of 2.2 μM. It disrupts bacterial membrane integrity, reducing metabolic activity. By binding to DNA grooves, it inhibits replication and induces reactive oxygen species (ROS) accumulation, leading to bacterial death. Antibacterialagent 271 shows considerable potential in combating bacterial infections.</p>
    Color and Shape:Odour Solid

    Ref: TM-T206586

  • HOE 33187-O-CONH-PEG4-phenol-thiophenone-NHPh-COOEt
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    HOE 33187-O-CONH-PEG4-phenol-thiophenone-NHPh-COOEt

    CAS:
    <p>HOE 33187-O-CONH-PEG4-phenol-thiophenone-NHPh-COOEt inhibits pre-miR-21 RNA, potential for cancer research.</p>
    Formula:C57H62N8O10S
    Color and Shape:Solid
    Molecular weight:1051.21

    Ref: TM-T74244

  • TAS-119
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    TAS-119

    CAS:
    <p>TAS-119 (TAS-2104) is an orally available, selective and potent inhibitor of Aurora A with an IC50 of 1.0 nM.TAS-119 also inhibits Aurora B with an IC50 of 95</p>
    Formula:C23H22Cl2FN5O3
    Purity:99.65%
    Color and Shape:Solid
    Molecular weight:506.36

    Ref: TM-T34787

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    N1-Methyl-2'-β-C-methyl adenosine

    <p>N1-Methyl-2’-beta-C-methyl adenosine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies.</p>
    Formula:C12H17N5O4
    Color and Shape:Solid
    Molecular weight:295.29

    Ref: TM-T75056

  • CDK9 ligand 3
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    CDK9 ligand 3

    CAS:
    <p>CDK9ligand 3 is a ligand for CDK9 and can be utilized in the synthesis of PROTAC degraders, specifically PROTAC CDK9degrader-11.</p>
    Formula:C18H18BrCl2N5O3
    Color and Shape:Solid
    Molecular weight:503.177

    Ref: TM-T205690

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    Farletuzumab

    CAS:
    <p>Farletuzumab (MORAb-003), a humanized antibody, inhibits FRα-expressing cell growth for cancer research.</p>
    Purity:> 95%
    Color and Shape:Liquid
    Molecular weight:145.36 kDa

    Ref: TM-T76720

  • CDK1-IN-2
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    CDK1-IN-2

    CAS:
    <p>CDK1-IN-2 (cdk1 inhibitor 2) is a CDK1 inhibitor with IC50 of 5.8 μM.</p>
    Formula:C17H11ClN2O
    Purity:98.53%
    Color and Shape:Soild
    Molecular weight:294.73

    Ref: TM-T64373

  • KWR137
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    KWR137

    <p>KWR137 is a WRN degrader with an IC50 of 8 nM. It exhibits significant antiproliferative activity against MSI-H cells, with a GI50 of 509 nM for SW48 cells and 824 μM for HCT116. Additionally, KWR137 demonstrates antitumor growth effects in xenograft mouse models. This compound is applicable for cancer research.</p>
    Formula:C33H31ClF3N9O4
    Color and Shape:Solid
    Molecular weight:710.105

    Ref: TM-T205674

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    PROTAC CDK9 degrader-8

    <p>PROTAC CDK9 Degrader-8 (Compound 21) is a potent degrader of CDK9 with an IC50 of 0.01 μM, utilized in cancer research [1].</p>
    Formula:C44H52Cl2N10O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:903.85

    Ref: TM-T78928

  • MYC-IN-2
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    MYC-IN-2

    CAS:
    <p>MYC-IN-2 is a protein-protein inhibitor targeting the MYC protein, designed for use in cancer research.</p>
    Formula:C25H17N3O2S
    Color and Shape:Solid
    Molecular weight:423.49

    Ref: TM-T39751

  • Apcin A HCL
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    Apcin A HCL

    CAS:
    <p>Apcin A HCL is an Apcin-derived APC inhibitor that binds Cdc20 and hinders ubiquitination, useful for synthesizing PROTAC CP5V.</p>
    Formula:C10H15Cl4N5O2
    Purity:99.59%
    Color and Shape:Solid
    Molecular weight:379.07

    Ref: TM-T64339

  • Echistatin
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    Echistatin

    CAS:
    <p>Potent αVβ3 integrin blocker, stops osteoclast binding &amp; bone loss, hinders platelet aggregation. Ki=0.27 nM, IC50s: 0.1 nM (bone), 30 nM (platelets).</p>
    Formula:C217H341N71O74S9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:5417.1

    Ref: TM-TP2098

  • (E/Z)-THZ1 2HCl
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    (E/Z)-THZ1 2HCl

    CAS:
    <p>THZ1 2HCl: selective CDK7 allosteric inhibitor, IC50 3.2 nM, hinders cancer cell growth.</p>
    Formula:C31H30Cl3N7O2
    Purity:99.51%
    Color and Shape:Solid
    Molecular weight:638.98

    Ref: TM-T35332

  • Phen-DC3 Trifluoromethanesulfonate
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    Phen-DC3 Trifluoromethanesulfonate

    CAS:
    <p>Phen-DC3 Trifluoromethanesulfonate targets G-quadruplexes and inhibits FANCJ/DinG helicases; IC50s: 65±6/50±10 nM.</p>
    Formula:C36H26F6N6O8S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:848.75

    Ref: TM-T13817L

  • Clofarabine-5'-diphosphate
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    Clofarabine-5'-diphosphate

    CAS:
    <p>Clofarabine-5'-diphosphate (Clofarabine-DP) is a metabolite resulting from the phosphorylation of Clofarabine by deoxycytidine kinase (dCK). It can undergo further phosphorylation to become Clofarabine-5'-triphosphate, exhibiting cytotoxicity in cancer cells by inhibiting DNA synthesis and repair.</p>
    Formula:C10H13ClFN5O9P2
    Color and Shape:Solid
    Molecular weight:463.64

    Ref: TM-T203181

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    2-Amino-3',5'-di-O-acetyl-N6,N6-dimethyl-2'-O-methyladenosine

    <p>2-Amino-3’,5’-di-O-acetyl-N6,N6-dimethyl-2’-O-methyladenosine is an adenosine analog.</p>
    Formula:C17H24N6O6
    Color and Shape:Solid
    Molecular weight:408.41

    Ref: TM-T75227

  • LB80317
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    LB80317

    CAS:
    <p>LB-80317, a DNA polymerase inhibitor, is used potentially for the potential treatment of hepatitis B virus infection.</p>
    Formula:C10H14N5O5P
    Color and Shape:Solid
    Molecular weight:315.22

    Ref: TM-T27801

  • 2'-β-C-Methyl-3-deazauri dine
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    2'-β-C-Methyl-3-deazauri dine

    CAS:
    <p>2’-β-C-Methyl-3-deazauridine, a purine nucleoside analogue, exhibits wide antitumor activity specifically against indolent lymphoid malignancies.</p>
    Formula:C11H15NO6
    Color and Shape:Solid
    Molecular weight:257.24

    Ref: TM-T75077

  • LXY3
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    LXY3

    CAS:
    <p>LXY3 (LXY2) is a VLA-3 blocking peptide that inhibits the interaction of neutrophil surface integrin α3β1 (VLA-3) with laminin in the basement membrane, thereby preventing neutrophil migration across the tumor vascular basement membrane barrier. LXY3 is employed to block the neutrophil-mediated release of nanoparticles from the perivascular pool into the tumor stroma and is frequently used for targeted imaging in breast cancer.</p>
    Formula:C32H43N11O15S2
    Color and Shape:Solid
    Molecular weight:885.88

    Ref: TM-TP3270

  • Eesperamicin A1
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    Eesperamicin A1

    CAS:
    <p>Esperamicin A1, a powerful antitumor drug, comes from Actinomadura verrucosospora.</p>
    Formula:C59H80N4O22S4
    Color and Shape:Solid
    Molecular weight:1325.54

    Ref: TM-T41140