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Cell Cycle/Checkpoint

Cell Cycle/Checkpoint

Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.

Subcategories of "Cell Cycle/Checkpoint"

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Found 3485 products of "Cell Cycle/Checkpoint"

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  • N4-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine


    <p>N4-Benzoyl-3'-O-DMT cytidine analog inhibits DNA methyltransferases like Zebularine.</p>
    Formula:C41H43N3O9
    Color and Shape:Solid
    Molecular weight:721.79
  • Lys-Gln-Ala-Gly-Asp-Val

    CAS:
    <p>KQAGDV is a fibrinogen γ-chain cell adhesion peptide, targeting α2bβ3 integrin, and binds SMCs.</p>
    Formula:C25H44N8O10
    Color and Shape:Solid
    Molecular weight:616.66
  • DHFR-IN-11


    <p>DHFR-IN-11 (compound 6b) is a DHFR inhibitor with demonstrated inhibitory efficacy against the M.</p>
    Color and Shape:Odour Solid
  • Erythromycin thiocyanate

    CAS:
    <p>Erythromycin thiocyanate, a macrolide from Streptomyces erythreus, binds 50S ribosomes, halting protein synthesis in bacteria.</p>
    Formula:C38H68N2O13S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:793.02
  • Zimistobart

    CAS:
    <p>Zimistobart (BMS-986315) is a fully human IgG1 antibody that targets and binds to NKG2A. It is applicable in research for non-small cell lung cancer (NSCLC). For an isotype control, refer to HumanIgG1kappa, Isotype Control.</p>
    Color and Shape:Liquid
  • Lysidine

    CAS:
    <p>Lysidine (2-Methyl-2-iMidazoline) is a nucleoside rarely seen outside of tRNA. Lysidine has better translation fidelity.</p>
    Formula:C4H8N2
    Purity:98%
    Color and Shape:Light Yellow To Off-White Crystalline
    Molecular weight:84.12
  • Fuzapladib

    CAS:
    <p>Fuzapladib (IS-741) is a PLA2 inhibitor that reduces Mac-1 expression to prevent inflammation and pancreatitis.</p>
    Formula:C15H20F3N3O3S
    Purity:99.87%
    Color and Shape:Soild
    Molecular weight:379.4
  • PROTAC CDK9 degrader-2

    CAS:
    <p>PROTAC CDK9 degrader-2, potent, selective, IC50 17 μM in MCF-7, wogonin-derived, targets CRBN.</p>
    Formula:C39H36N6O10
    Purity:98%
    Color and Shape:Solid
    Molecular weight:748.74
  • NUAK1-IN-1


    <p>NUAK1-IN-1 (Compound 9) is an inhibitor of NUAK1 with an IC50 of 5.012 nM, as well as a CDK4 inhibitor. It is suitable for research related to cancer, neurodevelopmental disorders, and Alzheimer's disease.</p>
    Formula:C25H30N6O
    Color and Shape:Solid
    Molecular weight:430.545
  • CGP-74514

    CAS:
    <p>CGP-74514,CDK1 inhibitor (IC50=25 nM). Induces G2/M arrest, apoptosis. Used in bladder cancer research.</p>
    Formula:C19H24ClN7
    Purity:98.54%
    Color and Shape:Soild
    Molecular weight:385.89
  • EC0488

    CAS:
    <p>EC0488 was used to synthesize EC0531, which has folic acid receptor specificity and anti-tumor activity.</p>
    Formula:C65H98N16O34S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1679.63
  • Nocarnickelamides B


    <p>Nocarnickelamides B (Compound 2) is a linear peptide and an inhibitor of ROCK1/2. It exhibits dual inhibitory activity against ROCK1 and ROCK2, with IC50 values of 14.9 μM and 21.9 μM, respectively. This compound binds to the ATP binding site and inhibits ROCK-mediated cytoskeletal contraction markers, such as myosin light chain activation. Nocarnickelamides B can be utilized in glaucoma research.</p>
    Formula:C29H42N6O9
    Color and Shape:Odour Solid
    Molecular weight:618.68
  • Bz-rC Phosphoramidite

    CAS:
    <p>Bz-rC Phosphoramidite is a phosphinamide monomer utilized for oligonucleotide synthesis.</p>
    Formula:C52H66N5O9PSi
    Color and Shape:Solid
    Molecular weight:964.185
  • m7GpppCpG

    CAS:
    <p>m7GpppCpG, a trinucleotide cap analogue, is used for synthesizing RNA with cap 0 or cap 1 structures.</p>
    Formula:C30H41N13O25P4
    Color and Shape:Solid
    Molecular weight:1107.61
  • Rachelmycin

    CAS:
    <p>Rachelmycin, a potent antibiotic and antitumor agent from Streptomyces zelensis, binds to DNA's minor groove.</p>
    Formula:C37H33N7O8
    Color and Shape:Solid
    Molecular weight:703.712
  • XT17


    <p>XT17 is an anthrone compound with broad-spectrum antibacterial activity, exerting its effects by disrupting the cell wall and inhibiting DNA synthesis. It demonstrates weak hemolytic activity, low cytotoxicity to mammalian cell lines, and a low rate of resistance development. Additionally, XT17 shows in vivo efficacy in a mouse corneal infection model induced by Staphylococcus aureus or Pseudomonas aeruginosa. Further docking studies confirm that XT17 forms a stable complex with bacterial gyrase. XT17 is suitable for research in the field of anti-infective agents.</p>
    Color and Shape:Odour Solid
  • Nitrosofolic acid

    CAS:
    <p>Nitrosofolic acid is a folic acid derivaive.</p>
    Formula:C19H18N8O7
    Color and Shape:Solid
    Molecular weight:470.40
  • CDK12-IN-2

    CAS:
    <p>CDK12-IN-2 selectively inhibits CDK12 (IC50: 52 nM) with minimal effect on CDK2, CDK7, and CDK9, useful for CDK12 research.</p>
    Formula:C32H32N6O2
    Purity:99.31%
    Color and Shape:Solid
    Molecular weight:532.64
  • Carboxy-pyridostatin

    CAS:
    <p>Carboxy-pyridostatin, as a fluorescent probe, can target G-quadruplex structures and trap cytoplasmic RNA G-quadruplex structures in cells.</p>
    Formula:C35H34N10O7
    Color and Shape:Solid
    Molecular weight:706.71
  • Psammaplin A

    CAS:
    <p>Psammaplin A: marine-derived, inhibits HDAC/DNA methyltransferases, strong DAC1 blocker (IC50=0.9nM), antimicrobial against Gram-positive bacteria, anticancer.</p>
    Formula:C22H24Br2N4O6S2
    Color and Shape:Solid
    Molecular weight:664.38