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Cell Cycle/Checkpoint

Cell Cycle/Checkpoint

Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.

Subcategories of "Cell Cycle/Checkpoint"

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Found 3485 products of "Cell Cycle/Checkpoint"

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  • N7-Methyl-2'-O-(2-methoxyethyl) guanosine


    <p>N7-Methyl-2’-O-(2-methoxyethyl) guanosine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies.</p>
    Formula:C14H21N5O6
    Color and Shape:Solid
    Molecular weight:355.35
  • Ac-dA Phosphoramidite

    CAS:
    <p>Ac-dA Phosphoramidite is a phosphinamide monomer utilized for oligonucleotide synthesis.</p>
    Formula:C42H50N7O7P
    Color and Shape:Solid
    Molecular weight:795.878
  • Mps1-IN-6


    <p>Mps1-IN-6 is a potent Mps1 inhibitor that demonstrates antiproliferative and antitumor activities, exhibiting an IC50 of 2.596 nM [1].</p>
    Formula:C35H39N9O3
    Color and Shape:Solid
    Molecular weight:633.74
  • Ribonuclease T1

    CAS:
    <p>Rnase T1, an endonuclease, degrades single-stranded RNA to yield 3'-GMP oligonucleotides.</p>
    Color and Shape:Solid
  • Dihydro-5-azacytidine

    CAS:
    <p>Dihydro-5-azacytidine (DHAC) is a nucleoside analog that interrupts DNA methylation by integrating into DNA. It also exhibits notable antitumor properties.</p>
    Formula:C8H14N4O5
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:246.22
  • BSJ-03-204

    CAS:
    <p>BSJ-03-204 is a selective Cdk4/6 degrader.</p>
    Formula:C43H48N10O8
    Color and Shape:Solid
    Molecular weight:832.9
  • 5'-O-DMT-ibu-dC

    CAS:
    <p>5'-O-DMT-ibu-dC can be used in the synthesis of oligodeoxyribonucleotides.</p>
    Formula:C34H37N3O7
    Color and Shape:Solid
    Molecular weight:599.67
  • Carboxy-pyridostatin

    CAS:
    <p>Carboxy-pyridostatin, as a fluorescent probe, can target G-quadruplex structures and trap cytoplasmic RNA G-quadruplex structures in cells.</p>
    Formula:C35H34N10O7
    Color and Shape:Solid
    Molecular weight:706.71
  • CDK12-IN-2

    CAS:
    <p>CDK12-IN-2 selectively inhibits CDK12 (IC50: 52 nM) with minimal effect on CDK2, CDK7, and CDK9, useful for CDK12 research.</p>
    Formula:C32H32N6O2
    Purity:99.31%
    Color and Shape:Solid
    Molecular weight:532.64
  • Biotin-PEG7-C2-S-Vidarabine


    <p>Biotin-PEG7-C2-S-Vidarabine: PEG linker with antiviral adenosine analog effective against herpes and zoster.</p>
    Formula:C36H60N8O12S2
    Color and Shape:Solid
    Molecular weight:861.04
  • Garenoxacin

    CAS:
    <p>Garenoxacin (BMS284756) is a novel oral des-fluoro(6) quinolone for the treatment of Gram-positive and Gram-negative bacterial infections.</p>
    Formula:C23H20F2N2O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:426.41
  • CDK12-IN-6

    CAS:
    <p>CDK12-IN-6, a pyrazolotriazine, strongly inhibits CDK12 (IC50 1.19 μM at 2 mM ATP), but not CDK2/Cyclin E or CDK9/Cyclin T1 (both IC50 &gt;20 μM).</p>
    Formula:C20H21F2N9
    Color and Shape:Solid
    Molecular weight:425.448
  • PLK1-IN-2

    CAS:
    <p>PLK1-IN-2 is a PLK1 kinase inhibitor with an IC 50 value of 0.384 μM.</p>
    Formula:C24H27FN8OS
    Color and Shape:Solid
    Molecular weight:494.59
  • GSK299423

    CAS:
    <p>GSK299423: Antibiotic possibly effective against bacteria with New Delhi metal-β-lactamase, targeting topoisomerases.</p>
    Formula:C25H27N5O2S
    Purity:97.34%
    Color and Shape:Solid
    Molecular weight:461.58
  • Nocarnickelamides B


    <p>Nocarnickelamides B (Compound 2) is a linear peptide and an inhibitor of ROCK1/2. It exhibits dual inhibitory activity against ROCK1 and ROCK2, with IC50 values of 14.9 μM and 21.9 μM, respectively. This compound binds to the ATP binding site and inhibits ROCK-mediated cytoskeletal contraction markers, such as myosin light chain activation. Nocarnickelamides B can be utilized in glaucoma research.</p>
    Formula:C29H42N6O9
    Color and Shape:Odour Solid
    Molecular weight:618.68
  • CD532 hydrochloride


    <p>CD532 hydrochloride, potent Aurora A inhibitor (IC50=45 nM), hampers MYCN protein, changes AURKA's shape, aids cancer research.</p>
    Color and Shape:Solid
  • Anti-MRSA agent 7


    <p>Compound 12: a potent anti-MRSA, inhibits S. aureus/E. coli DNA gyrases/topo IV; IC50: 0.185-0.365/0.341-0.059 μM.</p>
    Formula:C22H20BrF2N3O4
    Color and Shape:Solid
    Molecular weight:508.31
  • Filanesib TFA

    CAS:
    <p>Filanesib (ARRY-520) inhibits KSP, triggering mitotic arrest and cell death in dividing tumor cells.</p>
    Formula:C22H23F5N4O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:534.5
  • Adenosine Dialdehyde (ADOX)

    CAS:
    <p>Adenosine Dialdehyde, a purine analogue, inhibits SAHH (Ki=3.3 nM), and shows strong anti-tumor effects in vivo.</p>
    Formula:C10H11N5O4
    Purity:95%
    Color and Shape:Solid
    Molecular weight:265.23
  • CDK7-IN-5

    CAS:
    <p>CDK7-IN-5, a CDK7 inhibitor with an IC 50 value of less than 100 nM, exhibits potent anticancer properties (WO2015154022A1, Compound 104).</p>
    Formula:C34H45N9O2
    Color and Shape:Solid
    Molecular weight:611.795