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Cell Cycle/Checkpoint

Cell Cycle/Checkpoint

Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.

Subcategories of "Cell Cycle/Checkpoint"

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Found 3480 products of "Cell Cycle/Checkpoint"

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  • 5'-O-DMT-PAC-dA

    CAS:
    <p>5’-O-DMT-PAC-dA can be used in the synthesis of oligoribonucleotides[1].</p>
    Formula:C39H37N5O7
    Color and Shape:Solid
    Molecular weight:687.74
  • LDV FITC

    CAS:
    <p>fluorescent ligand that binds to the α4β1 integrin (VLA-4)</p>
    Formula:C69H81N11O17S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1368.53
  • Erythromycin A dihydrate

    CAS:
    <p>Erythromycin dihydrate, a macrolide antibiotic from Streptomyces erythreus, targets 50S ribosomal subunits, blocking protein synthesis.</p>
    Formula:C37H69NO14
    Color and Shape:Solid
    Molecular weight:751.94
  • AV-153

    CAS:
    <p>AV-153, a 1,4-dihydropyridine, reduces DNA damage, stimulates repair, and has anti-cancer properties.</p>
    Formula:C14H19NNaO6
    Color and Shape:Solid
    Molecular weight:320.297
  • 8-NH2-ATP

    CAS:
    <p>8-NH2-ATP is an inactive derivative of adenosine triphosphate (ATP), synthesized from 8-NH2-Ado.</p>
    Formula:C10H17N6O13P3
    Color and Shape:Solid
    Molecular weight:522.20
  • 5-Caroxy uracil-1-yl acetic acid benzyl ester


    <p>5-Caroxy uracil-1-yl acetic acid benzyl ester, a purine analog, inhibits DNA synthesis and induces apoptosis to combat lymphoid cancers.</p>
    Formula:C14H12N2O6
    Color and Shape:Solid
    Molecular weight:304.25
  • Isocytosine

    CAS:
    <p>Compound PDK0016, with CAS No. 108-53-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0016 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>
    Formula:C4H5N3O
    Color and Shape:White To Off-White Solid
    Molecular weight:111.1
  • IV-361

    CAS:
    <p>IV-361, an orally active and selective CDK7 inhibitor with a Ki value of less than or equal to 50 nM, demonstrates potent anti-cancer activity (US20190256531A1</p>
    Formula:C23H32FN5O2Si
    Color and Shape:Solid
    Molecular weight:457.625
  • Rev 2'-O-MOE-C(Bz)-5'-amidite


    <p>'Rev 2’-O-MOE-C(Bz)-5’-amidite, a purine nucleoside analog, exhibits broad antitumor activity against indolent lymphoid malignancies.</p>
    Formula:C49H58N5O10P
    Color and Shape:Solid
    Molecular weight:907.99
  • Dafsolimab

    CAS:
    <p>Dafsolimab (SPV-T3a), an IgG2a murine monoclonal antibody (anti-CD3), induces cell death by modulating and activating the CD3/T cell receptor complex and is</p>
    Color and Shape:Liquid
  • SR15006

    CAS:
    <p>SR15006 is Krüppel-like factor 5 (KLF5) inhibitor (IC50 = 41.6 nM).</p>
    Formula:C16H20ClN3O4S
    Purity:99.87%
    Color and Shape:Soild
    Molecular weight:385.87
  • Nogalamycin

    CAS:
    <p>Nogalamycin is an anthracycline antibiotic with antitumor properties produced by soil bacteria Streptomyces nogalater.</p>
    Formula:C39H49NO16
    Purity:98%
    Color and Shape:Solid
    Molecular weight:787.812
  • Chrexanthomycin C


    <p>Chrexanthomycin C, orally active, binds DNA (G4C2)4 G4, Kd 2.8 mM, potential in ALS research.</p>
    Formula:C31H24O15
    Color and Shape:Solid
    Molecular weight:636.51
  • Ac-MRGDH-NH2


    <p>Ac-MRGDH-NH2 is a pentapeptide containing the RGD sequence. It is utilized in the synthesis of the diastereomeric prodrugs Λ- and Δ-[Ru(Ph2phen)2(κS,κN-(Ac-MRGDH-NH2))]Cl2. In these prodrugs, Ac-MRGDH-NH2 serves as a photolabile protecting group for the cytotoxic diruthenium aqua complexes [Ru(Ph2phen)2(OH2)2]2+, offering integrin targeting and photoactivation properties. Consequently, Ac-MRGDH-NH2 can be applied in studies exploring tumor-targeted photoactivatable chemotherapy.</p>
    Formula:C25H41N11O8S
    Color and Shape:Solid
    Molecular weight:655.727
  • DHFR-IN-8


    <p>DHFR-IN-8 (compound 6r), a dihydrofolate reductase (DHFR) inhibitor, disrupts purine and thymidylate biosynthesis critical for cell proliferation and growth.</p>
    Formula:C18H14N6S
    Color and Shape:Solid
    Molecular weight:346.41
  • N1-Methylpseudouridine-5′-triphosphate tetralithium


    <p>N1-Methylpseudouridine-5′-triphosphate tetralithium, also known as 1-Methylpseudouridine-5′-triphosphate tetralithium, is a nucleobase-modified nucleotide.</p>
    Formula:C10H13Li4N2O15P3
    Color and Shape:Solid
    Molecular weight:521.9
  • GRGDSP

    CAS:
    <p>Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP) is used as a soluble integrin-blocking RGD-based peptide.</p>
    Formula:C22H37N9O10
    Purity:98%
    Color and Shape:Solid
    Molecular weight:587.58
  • 3'-β-C-Methyl-N6-isopentenyl adenosine


    <p>3’-Beta-C-Methyl-N6-isopentenyl adenosine is an adenosine analog.</p>
    Formula:C16H23N5O4
    Color and Shape:Solid
    Molecular weight:349.38
  • Brr2-IN-2


    <p>Brr2-IN-2 (Compound 30) is an inhibitor of Brr2, exhibiting an IC50 of 42 nM against Brr2 ATPase.</p>
    Formula:C21H25FN4O2
    Color and Shape:Solid
    Molecular weight:384.45
  • 3'-Deoxy-GTP trisodium


    <p>3'-Deoxy-GTP (3′-Deoxyguanosine 5′-triphosphate) trisodium, an analog of GTP, functions as an RNA chain terminator, thereby inhibiting RNA synthesis. It is capable of suppressing dengue virus DENV NS5 RdRp with an IC50 value of 0.02 μM.</p>
    Color and Shape:Odour Solid