Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase(114 products)
- CDK(546 products)
- Cell Cycle Arrest(5 products)
- Chk(48 products)
- DYRK(47 products)
- Dynamin(27 products)
- Ferroptosis(226 products)
- HSP(179 products)
- Integrin(253 products)
- Kinesin(87 products)
- LIM Kinase(20 products)
- Microtubule Associated(273 products)
- PKC(124 products)
- PLK(25 products)
- ROCK(62 products)
- Rho(6 products)
- Wee1(14 products)
- c-Myc(76 products)
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Found 3874 products of "Cell Cycle/Checkpoint"
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EFdA-TP tetraammonium
EFdA-TP tetraammonium is a potent HIV-1 RT inhibitor and DNA synthesis blocker, acting as an ICT or DCT.Formula:C12H27N9O12P3Color and Shape:SolidMolecular weight:601.31Evybactin
Evybactin: a selective DNA gyrase inhibitor for Mycobacterium tuberculosis (MIC 0.25 µg/mL), first of its kind.Formula:C64H89N21O21Color and Shape:SolidMolecular weight:1488.52DSPE-PEG2000-iRGD
DSPE-PEG2000-iRGD is a PEG compound composed of DSPE and the αv-integrin targeting peptide (iRGD). The iRGD peptide binds to αv-integrins and subsequently undergoes proteolytic cleavage within tumors, producing CRGDK/R, which interacts with neuropilin-1. This compound is characterized by its tumor-targeting and tumor-penetrating properties, making DSPE-PEG2000-iRGD suitable for drug delivery applications.Color and Shape:Odour SolidFF-10502
CAS:FF-10502, a pyrimidine analog of Gemcitabine, inhibits DNA polymerases α/β, targeting dormant cancer cells.Formula:C9H12FN3O3SColor and Shape:SolidMolecular weight:261.27N7-Methyl-guanosine-5'-triphosphate-5'-adenosine diammonium
CAS:N7-Methylguanosine-5'-triphosphate-5'-adenosine (m7GpppA) diammonium, a dinucleotide cap analog, facilitates in vitro RNA transcription [1].
Formula:C21H35N12O17P3Color and Shape:SolidMolecular weight:820.49STX-100
PY314 is a CHO-expressed humanized monoclonal antibody targeting TREM2 with antitumor activity for the study of metastatic renal cell carcinoma.Purity:97.3% (SDS-PAGE); 97.5% (SEC-HPLC) - 97.3% (SDS-PAGE); 97.5% (SEC-HPLC)Color and Shape:Odour LiquidMolecular weight:145.12 kDaRNA splicing modulator 1
CAS:RNA Splicing Modulator 1 (Compound 233) is a modulator of RNA splicing, exhibiting an AC50 value of less than 100 nM [1].
Formula:C19H20N6OSColor and Shape:SolidMolecular weight:380.47R-1479
CAS:R-1479 (4'-Azidocytidine) is an RdRp inhibitor with an IC50 value of 1.28 μM for HCV RNA replication in the HCV subgenomic replicon system.Formula:C9H12N6O5Purity:98.11% - 99.95%Color and Shape:SolidMolecular weight:284.23Ref: TM-TQ0162
1mg104.00€5mg258.00€10mg358.00€25mg595.00€50mg842.00€100mg1,134.00€200mg1,521.00€1mL*10mM (DMSO)318.00€AD16
CAS:AD16 (Acetamide) acts as an inhibitor of LINE-1 retrotransposon endonuclease, exhibiting an IC50 value of 4.7 μM. It decreases LINE-1 retrotransposition in senescent cells and mitigates the resulting DNA damage and inflammation.Formula:C24H20N14O3S2Color and Shape:SolidMolecular weight:616.64CBP501 Affinity Peptide
CAS:CBP501 Affinity Peptide, a Chk kinase inhibitor, disrupts G2 arrest triggered by DNA-damaging agents and is utilized in cancer research [1].Formula:C68H119N21O25SColor and Shape:SolidMolecular weight:1662.86ROCK-IN-32
CAS:ROCK-IN-32 is an effective Rho-kinase inhibitor.Formula:C20H17Cl2N3O2Purity:98%Color and Shape:SolidMolecular weight:402.27Bimosiamose disodium
CAS:Bimosiamose disodium (TBC-1269Z), a pan-selectin inhibitor, has IC50s: E-selectin 88 μM, P-selectin 20 μM, L-selectin 86 μM; anti-inflammatory.Formula:C46H52Na2O16Purity:98%Color and Shape:SolidMolecular weight:906.88RP-1664
CAS:RP-1664,PLK4 inhibitor (IC50=3 nM). Disrupts centriole biogenesis. Antitumor activity in breast cancer, neuroblastoma.Formula:C23H24F2N8O2SPurity:99.04%Color and Shape:SoildMolecular weight:514.55dCeMM3
CAS:dCeMM3 is a glue degrader that induces ubiquitination and degradation of cyclin K by promoting CDK12-cyclin K interaction with CRL4B ligase.
Formula:C14H11ClN4OSPurity:98.48% - 99.41%Color and Shape:SolidMolecular weight:318.78Aclacinomycin A
CAS:Aclacinomycin A has a wide range of applications in life science related research.Formula:C42H53NO15Purity:99.43%Color and Shape:SolidMolecular weight:811.87(S)-DI-87
CAS:(S)-DI-87 is an isomer of DI-87, a oral dCK inhibitor，reduce dNTP production and cell cycle arrest. significantly inhibits tumor growth with thymidine.Formula:C23H30N6O3S2Purity:99.42%Color and Shape:SoildMolecular weight:502.65Ref: TM-T39550L
1mg185.00€5mg459.00€10mg657.00€25mg1,026.00€50mg1,415.00€100mg1,872.00€200mg2,555.00€5'(R)-C-Methyl-5-fluorouridine
5’(R)-C-Methyl-5-fluorouridine, a uridine analogue, possesses potential antiepileptic properties.Formula:C10H13FN2O6Color and Shape:SolidMolecular weight:276.22CPS2
CAS:CPS2: potent, selective PROTAC CDK2 degrader. IC50=24nM, targets acute myeloid leukemia research.Formula:C38H42N12O10S2Color and Shape:SolidMolecular weight:890.94BLINK15
BLINK15 is a blood-brain barrier-permeable Cdk5 inhibitor. It reduces CDK5 activity in CDK5/p35 (IC50= 29.34 nM) and CDK5/p25 (IC50= 12.08 nM) complexes. Additionally, BLINK15 exhibits antidiabetic and neuroprotective effects. It lowers blood glucose levels in type 2 diabetes (T2D) mice, enhances cognitive abilities, and diminishes neurodegenerative lesions.Color and Shape:Odour SolidUridine triphosphate 13C9,15N2 sodium
CAS:Uridine triphosphate 13C9,15N2 sodium is an isotopically labeled.UTP is a key in RNA synthesis molecule a substrate for RNA polymerase.Formula:C9H1415N2NaO15P3Color and Shape:SolidMolecular weight:517.04
