Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase(114 products)
- CDK(546 products)
- Cell Cycle Arrest(5 products)
- Chk(48 products)
- DYRK(47 products)
- Dynamin(27 products)
- Ferroptosis(227 products)
- HSP(180 products)
- Integrin(268 products)
- Kinesin(87 products)
- LIM Kinase(20 products)
- Microtubule Associated(274 products)
- PKC(126 products)
- PLK(25 products)
- ROCK(62 products)
- Rho(6 products)
- Wee1(14 products)
- c-Myc(76 products)
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Found 3904 products of "Cell Cycle/Checkpoint"
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Cotylenin A
CAS:Cotylenin A is a phenanthraquinone compound that synergistically works with vitamin K2 to induce monocyte differentiation and growth arrest. It also inhibits c-Myc expression while inducing cyclin G2 expression in human leukemia HL-60 cells. Cotylenin A is applicable in acute myeloid leukemia research.Formula:C33H50O11Color and Shape:SolidMolecular weight:622.744Alliacol B
CAS:Alliacol B is an antibiotic with mild antibacterial and antifungal properties. It can inhibit DNA synthesis in Ehrlich ascites carcinoma cells.Formula:C15H20O4Color and Shape:SolidMolecular weight:264.317Anticancer agent 264
Anticanceragent 264 (Compound 5w) is an anticancer compound that exhibits significant antiproliferative activity in tumor cell lines, with an IC50 range of 7.5-33.67 μM. It notably induces cell cycle arrest at the G2/M phase in MDA-MB-231, MIA PaCa-2, and DU-145 cell lines. This compound reduces key cell cycle proteins CDK1, CDK2, and Cyclin B1 in a dose-dependent manner and has strong binding activity with differentiation inhibitors and DNA-binding proteins. Anticanceragent 264 is useful for research in the cancer disease domain.Formula:C23H18ClF5N6OColor and Shape:SolidMolecular weight:524.87Agrocin 84
CAS:Agrocin 84 is a microbial metabolite that inhibits DNA and protein synthesis, as well as amino acid transport, in the susceptible and virulent Agrobacterium strain H-38-9.Formula:C22H36N6O16P2Color and Shape:SolidMolecular weight:702.499CRA-2059
CAS:CRA-2059 is a selective and reversible inhibitor of human tryptase beta, exhibiting a Ki value of 620 pM against recombinant human tryptase beta (rHTβ).Formula:C34H46N12O8Purity:97.68% - 99.29%Color and Shape:SolidMolecular weight:750.82CDK-IN-13
CDK-IN-13 (compound 32E) is a potent and selective inhibitor of CDK12/cyclin K, exhibiting an IC50 of 3 nM. Additionally, CDK-IN-13 suppresses the growth of HER2-positive breast cancer cell lines.Formula:C23H27N7O3Molecular weight:449.21754N6-Ethyl-2'-β-C-ethynyl adenosine
N6-Ethyl-2’-beta-C-ethynyl adenosine is a purine nucleoside analog.Formula:C14H17N5O4Color and Shape:SolidMolecular weight:319.32Phen-DC3 Trifluoromethanesulfonate
CAS:Phen-DC3 Trifluoromethanesulfonate targets G-quadruplexes and inhibits FANCJ/DinG helicases; IC50s: 65±6/50±10 nM.Formula:C36H26F6N6O8S2Purity:98%Color and Shape:SolidMolecular weight:848.75FRα-targeting peptide C7 TFA
FRα-targeting peptide C7 TFA is a selective peptide ligand for the folate receptor alpha (FRα) that specifically binds to FRα-expressing cells and has tumor-targeting capabilities in vivo. It is applicable in research related to tumor diagnosis and therapy.Color and Shape:Odour SolidFF-10502
CAS:FF-10502, a pyrimidine analog of Gemcitabine, inhibits DNA polymerases α/β, targeting dormant cancer cells.Formula:C9H12FN3O3SColor and Shape:SolidMolecular weight:261.275-Aza-xylo-cytidine
5-Aza-xylo-cytidine, a purine analog with antitumor effects, inhibits DNA synthesis and induces apoptosis in lymphoid cancers.Formula:C8H12N4O5Color and Shape:SolidMolecular weight:244.2Deoxythymidine-5'-triphosphate
CAS:Deoxythymidine-5'-triphosphate (dTTP) is a nucleoside triphosphate involved in DNA synthesis.Formula:C10H17N2O14P3Color and Shape:SolidMolecular weight:482.167RNA polymerase II-IN-2
RNA Pol II-IN-2 (20iii) strongly inhibits Pol II (Ki=9.5 nM), is more toxic to CHO/HEK293 than α-amanitin.Formula:C41H58N10O12SColor and Shape:SolidMolecular weight:915.025'-DMT-3'-CE-2'-TBDMS cyanoethoxycarbonyl-cytidine
CAS:5'-DMT-3'-CE-2'-TBDMS cyanoethoxycarbonyl-cytidine is a nucleotide analog used in nucleic acid synthesis.Formula:C49H65N6O10PSiColor and Shape:SolidMolecular weight:957.13SNX7
CAS:SNX7 (WAY-323879) inhibits CDKI pathway; useful for studying aging and related diseases.Formula:C15H14N2OPurity:99.96%Color and Shape:SolidMolecular weight:238.28Emicoron
CAS:Importazole is an inhibitor of the transport receptor importin-β. It specifically inhibits importin-β likely by altering its interaction with RanGTP.Formula:C52H58N6O4Purity:98%Color and Shape:SolidMolecular weight:831.055'-O-TBDMS-N2-ibu-dG
CAS:5'-O-TBDMS-N2-ibu-dG: a nucleoside derivative with strong anti-BVDV activity, useful in lead compound synthesis.Formula:C20H33N5O5SiColor and Shape:SolidMolecular weight:451.59Carbazole
CAS:Carbazole belongs to the class of carbazole-based organic compounds. Carbazole can form novel DNA small groove complexes, inhibiting the synthesis of new DNA or RNA.Formula:C12H9NPurity:99.82%Color and Shape:SolidMolecular weight:167.211CCT241533 dihydrochloride
CAS:Potent Chk2 inhibitor with 3 nM IC50, 63-fold more selective over Chk1, affects 84 kinases, reduces DNA damage response and apoptosis in cells.Formula:C23H29Cl2FN4O4Color and Shape:SolidMolecular weight:515.417-TFA-ap-7-Deaza-ddA
CAS:Compound 19c is a nucleotide derivative for DNA sequencing dye terminators.Formula:C16H16F3N5O3Color and Shape:SolidMolecular weight:383.331
