Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase(114 products)
- CDK(546 products)
- Cell Cycle Arrest(5 products)
- Chk(48 products)
- DYRK(47 products)
- Dynamin(27 products)
- Ferroptosis(227 products)
- HSP(180 products)
- Integrin(269 products)
- Kinesin(87 products)
- LIM Kinase(20 products)
- Microtubule Associated(274 products)
- PKC(126 products)
- PLK(25 products)
- ROCK(62 products)
- Rho(6 products)
- Wee1(14 products)
- c-Myc(76 products)
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Found 3904 products of "Cell Cycle/Checkpoint"
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Purine riboside-5'-O-triphosphate sodium
CAS:Purine riboside-5'-O-triphosphate sodium is an active metabolite of Nebularine and acts as an inhibitor of DNA primase ATP and GTP polymerization activities, with IC50 values of 35 µM and 28 µM, respectively. It also inhibits calmodulin-dependent protein kinase II (CaMKII), with a Ki value of 590 µM.Formula:C10H11N4Na4O13P3Color and Shape:SolidMolecular weight:580.09CDK8/19-IN-3
CDK8/19-IN-3 (compound 3-7) is a potent and selective inhibitor of CDK8 and CDK19. It can increase IL-10 levels and has potential for research in inflammatory bowel disease (IBD).Formula:C20H23FN6O2Color and Shape:SolidMolecular weight:398.434N1-Methylpseudouridine-5′-triphosphate tetralithium
N1-Methylpseudouridine-5′-triphosphate tetralithium, also known as 1-Methylpseudouridine-5′-triphosphate tetralithium, is a nucleobase-modified nucleotide.Formula:C10H13Li4N2O15P3Color and Shape:SolidMolecular weight:521.92'-Chloro-N6-(3-trifluoromethyl)benzyl adenosine
2’-Chloro-N6-(3-trifluoromethyl)benzyl adenosine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoidFormula:C18H17ClF3N5O4Color and Shape:SolidMolecular weight:459.81Py-MAA-Val-Cit-PAB-DX8951
CAS:Py-MAA-Val-Cit-PAB-DX8951, a purine toxin, serves as an intermediate in the synthesis of antibody-drug conjugates [1].Formula:C57H66FN11O13SColor and Shape:SolidMolecular weight:1164.26CPS2
CAS:CPS2: potent, selective PROTAC CDK2 degrader. IC50=24nM, targets acute myeloid leukemia research.Formula:C38H42N12O10S2Color and Shape:SolidMolecular weight:890.946-Methoxypurine-9-β-D-(3-methoxy riboside)
6-Methoxypurine riboside is a purine analog with anti-lymphoma activity via DNA synthesis inhibition and apoptosis induction.Formula:C12H16N4O5Color and Shape:SolidMolecular weight:296.286-Amino-4-hydrozino-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine
6-Amino-4-hydrozino-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine is a purine nucleoside analogue with broad antitumor activity, particularly againstFormula:C10H15N7O4Color and Shape:SolidMolecular weight:297.27CDP-β-S trisodium salt
CDP-β-S (Cytidine-5'-O-(2-thiodiphosphate)) trisodium salt is a non-hydrolyzable analog of CDP (Cytidine Diphosphate) with antioxidant and free radical scavenging properties.Color and Shape:Odour SolidZIKV-IN-6
ZIKV-IN-6 (compound 22) acts as a direct inhibitor of the Zika virus (ZIKV) by binding to its RNA-dependent RNA polymerase (RdRp) and obstructing viral RNAColor and Shape:Odour SolidGuanosine 5'-triphosphate trisodium salt hydrate
CAS:5'-GTP trisodium salt hydrate activates G proteins and is a precursor for DNA/RNA synthesis.Formula:C10H18N5NaO15P3Purity:98%Color and Shape:SolidMolecular weight:564.185Ascochlorin A
CAS:Ascochlorin A, a compound with a dissociation constant (K D) of 3.29 μM, serves as a novel and potent human dihydroorotate dehydrogenase (hDHODH) inhibitorFormula:C23H31ClO4Color and Shape:SolidMolecular weight:406.95PDI-IN-4
PDI-IN-4 (Compound 14d) is a protein disulfide isomerase inhibitor with an IC50 value of 0.48 μM. It prevents platelet aggregation and thrombosis by reducing the activation of GPIIb/IIIa, without causing significant cytotoxicity. PDI-IN-4 is applicable in thrombosis research.Formula:C17H12F3NO2Color and Shape:SolidMolecular weight:319.278AAK1-IN-7
AAK1-IN-7 (Compound 16) is a dual inhibitor of AAK1 and GAK with EC50 values of 40 nM and 80 nM, respectively. This compound inhibits the phosphorylation of the AP2-µ2 subunit at the T156 position. However, it demonstrates only weak antiviral activity against RNA viruses.Color and Shape:Odour SolidEMD527040 hydrochloride
EMD527040 (hydrochloride) is a potent and selective αvβ6 antagonist with antifibrotic properties. It is applicable in research related to liver cancer and hepatic fibrosis.Color and Shape:Odour SolidXanthosine-5'-Triphosphate
CAS:Xanthosine-5'-Triphosphate (5'-XTP), a nucleotide derived from the deamination of purine bases, plays a crucial role in various biological processes.Formula:C10H15N4O15P3Color and Shape:SolidMolecular weight:524.1645-Methylcytidine 5′-triphosphate
CAS:5-Methylcytidine 5′-triphosphate (5-Methyl-CTP), a modified nucleoside triphosphate, enhances translational properties and stability while reducing innateFormula:C10H18N3O14P3Color and Shape:SolidMolecular weight:497.18LY2812223
CAS:LY2812223: selective mGlu2 agonist; binds mGlu2/mGlu3 (Ki=144/156 nM).Formula:C10H12N4O4SPurity:98%Color and Shape:SolidMolecular weight:284.294,6-Dichloroguaiacol
CAS:4,6-Dichloroguaiacol elicits biochemical and morphological alterations in human peripheral blood lymphocytes in vitro.Formula:C7H6Cl2O2Color and Shape:SolidMolecular weight:193.02Rev 2'-O-MOE-C(Bz)-5'-amidite
'Rev 2’-O-MOE-C(Bz)-5’-amidite, a purine nucleoside analog, exhibits broad antitumor activity against indolent lymphoid malignancies.Formula:C49H58N5O10PColor and Shape:SolidMolecular weight:907.99
