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Cell Cycle/Checkpoint

Cell Cycle/Checkpoint

Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.

Subcategories of "Cell Cycle/Checkpoint"

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Found 3477 products of "Cell Cycle/Checkpoint"

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  • WRN inhibitor 17

    CAS:
    <p>WRN inhibitor 17 (Compound 250) is an orally active inhibitor of Werner syndrome ATP-dependent helicase (WRN), specifically targeting the helicase domain activity of WRN. It holds potential for use in cancer research.</p>
    Formula:C33H34F4N4O6S
    Color and Shape:Solid
    Molecular weight:690.71
  • MRK-952


    <p>MRK-952 is a NUDIX hydrolase inhibitor. NUDIX enzymes play a role in cellular metabolism, homeostasis, and mRNA processing.</p>
    Formula:C20H20ClF3N6
    Color and Shape:Solid
    Molecular weight:436.861
  • Clofarabine-5'-diphosphate

    CAS:
    <p>Clofarabine-5'-diphosphate (Clofarabine-DP) is a metabolite resulting from the phosphorylation of Clofarabine by deoxycytidine kinase (dCK). It can undergo further phosphorylation to become Clofarabine-5'-triphosphate, exhibiting cytotoxicity in cancer cells by inhibiting DNA synthesis and repair.</p>
    Formula:C10H13ClFN5O9P2
    Color and Shape:Solid
    Molecular weight:463.64
  • PROTAC MTP3 degrade-1


    <p>PROTACMTP3 degrade-1 is a PROTAC degrader for MYC.</p>
    Formula:C44H38N6O8
    Color and Shape:Solid
    Molecular weight:778.27511
  • 5-Methylcytidine 5′-triphosphate trisodium


    <p>5-Methylcytidine 5′-triphosphate trisodium (5-Methyl-CTP trisodium), a modified nucleoside triphosphate, enhances translational properties and stability, while</p>
    Formula:C10H15N3Na3O14P3
    Color and Shape:Solid
    Molecular weight:563.13
  • Echistatin

    CAS:
    <p>Potent αVβ3 integrin blocker, stops osteoclast binding &amp; bone loss, hinders platelet aggregation. Ki=0.27 nM, IC50s: 0.1 nM (bone), 30 nM (platelets).</p>
    Formula:C217H341N71O74S9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:5417.1
  • AURKA against 1


    <p>Compound Ac13, also termed AURKA against 1, acts as an inhibitor of the Aurora kinase (AURKA) with an IC50 of less than 0.5 nM, targeting the acetylation of endogenous lysine (K162) and exhibiting anti-tumor cell proliferation activity. The kinase activity of AURKA, acetylated at K162 and induced by AURKA against 1, is reversibly restored in HCT116 cells transfected with SIRT3.</p>
    Formula:C28H32FN9O2
    Color and Shape:Solid
    Molecular weight:545.61
  • 11H-Benzo[a]carbazole

    CAS:
    <p>11H-Benzo[a]carbazole is a kinesin-like protein KIF11 inhibitor that can inhibit the viability of HeLa cells.</p>
    Formula:C16H11N
    Purity:99.14%
    Color and Shape:Solid
    Molecular weight:217.27
  • CTP Synthetase-IN-1 Ammonium salt


    <p>CTP Synthetase-IN-1 Ammonium salt is a CTPS inhibitor with potential antibacterial, anti-inflammatory, and antitumor activity for the study of SARS-CoV-2 viral infections</p>
    Formula:C20H22F3N7O3S2
    Purity:99.97%
    Color and Shape:Solid
    Molecular weight:529.56
  • TAS-119

    CAS:
    <p>TAS-119 (TAS-2104) is an orally available, selective and potent inhibitor of Aurora A with an IC50 of 1.0 nM.TAS-119 also inhibits Aurora B with an IC50 of 95</p>
    Formula:C23H22Cl2FN5O3
    Purity:99.65%
    Color and Shape:Solid
    Molecular weight:506.36
  • Lorutengitide

    CAS:
    <p>Lorutengitide is a transcription-regulating peptide with antiproliferative activity.</p>
    Formula:C30H50N8O12
    Color and Shape:Solid
    Molecular weight:714.764
  • SMS 121

    CAS:
    <p>SMS 121 is a novel CD36 inhibitor that impairs fatty acid uptake and cell viability in acute myeloid leukaemia (AML) cells.</p>
    Formula:C20H21NO5
    Purity:98.29%
    Color and Shape:Soild
    Molecular weight:355.38
  • WAY-647802

    CAS:
    <p>WAY-647802 is a CDK inhibitor.</p>
    Formula:C11H14N4O3
    Purity:99.53%
    Color and Shape:Solid
    Molecular weight:250.25
  • Carboxy pyridostatin trifluoroacetate salt


    <p>Carboxy pyridostatin trifluoroacetate salt exhibits higher molecular specificity for RNA over DNA G4s.</p>
    Formula:C37H35F3N10O9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:820.73
  • 5'-O-DMT-rI

    CAS:
    <p>5’-O-DMT-Ri can be used in the synthesis of oligoribonucleotides[1].</p>
    Formula:C31H30N4O7
    Color and Shape:Solid
    Molecular weight:570.59
  • DHFR-IN-8


    <p>DHFR-IN-8 (compound 6r), a dihydrofolate reductase (DHFR) inhibitor, disrupts purine and thymidylate biosynthesis critical for cell proliferation and growth.</p>
    Formula:C18H14N6S
    Color and Shape:Solid
    Molecular weight:346.41
  • JAMM protein inhibitor 2 

    CAS:
    <p>JAMM inhibitor 2 targets thrombin, Rpn11, MMP2 with IC50s 10, 46, 89 μM, aids cancer research.</p>
    Formula:C21H26N2O2
    Purity:98.57%
    Color and Shape:Solid
    Molecular weight:338.44
  • CCT241533 dihydrochloride

    CAS:
    <p>Potent Chk2 inhibitor with 3 nM IC50, 63-fold more selective over Chk1, affects 84 kinases, reduces DNA damage response and apoptosis in cells.</p>
    Formula:C23H29Cl2FN4O4
    Color and Shape:Solid
    Molecular weight:515.41
  • SNX7

    CAS:
    <p>SNX7 (WAY-323879) inhibits CDKI pathway; useful for studying aging and related diseases.</p>
    Formula:C15H14N2O
    Purity:99.05%
    Color and Shape:Solid
    Molecular weight:238.28
  • wrwyar-NH2 TFA


    <p>wrwyar-NH2 (TFA) serves as the control peptide for wrwycr-NH2.</p>
    Color and Shape:Odour Solid