CymitQuimica logo
Cell Cycle/Checkpoint

Cell Cycle/Checkpoint

Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.

Subcategories of "Cell Cycle/Checkpoint"

Show 10 more subcategories

Found 3477 products of "Cell Cycle/Checkpoint"

Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • CymitQuimica logo
    Targetmol
    + Info

    FRα-targeting peptide C7 TFA

    <p>FRα-targeting peptide C7 TFA is a selective peptide ligand for the folate receptor alpha (FRα) that specifically binds to FRα-expressing cells and has tumor-targeting capabilities in vivo. It is applicable in research related to tumor diagnosis and therapy.</p>
    Color and Shape:Odour Solid

    Ref: TM-TP3238

  • CymitQuimica logo
    Targetmol
    + Info

    3'-Deoxy-N6-(m-methoxy benzyl)adenosine

    <p>3’-Deoxy-N6-(m-methoxy benzyl)adenosine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies.</p>
    Formula:C18H21N5O4
    Color and Shape:Solid
    Molecular weight:371.39

    Ref: TM-T75050

  • SNX7
    Targetmol
    + Info

    SNX7

    CAS:
    <p>SNX7 (WAY-323879) inhibits CDKI pathway; useful for studying aging and related diseases.</p>
    Formula:C15H14N2O
    Purity:99.05%
    Color and Shape:Solid
    Molecular weight:238.28

    Ref: TM-T77613

  • Bromochloroacetonitrile
    Targetmol
    + Info

    Bromochloroacetonitrile

    CAS:
    <p>Bromochloroacetonitrile, a water disinfection by-product, is mutagenic and can break DNA strands.</p>
    Formula:C2HBrClN
    Color and Shape:Solid
    Molecular weight:154.39

    Ref: TM-T40933

  • Cimpuciclib
    Targetmol
    + Info

    Cimpuciclib

    CAS:
    <p>Cimpuciclib is a cyclin-dependent kinase(CDK) inhibitor and antineoplastic.</p>
    Formula:C30H35FN8O
    Color and Shape:Solid
    Molecular weight:542.663

    Ref: TM-T39674

  • MYC-IN-2
    Targetmol
    + Info

    MYC-IN-2

    CAS:
    <p>MYC-IN-2 is a protein-protein inhibitor targeting the MYC protein, designed for use in cancer research.</p>
    Formula:C25H17N3O2S
    Color and Shape:Solid
    Molecular weight:423.49

    Ref: TM-T39751

  • CymitQuimica logo
    Targetmol
    + Info

    Catumaxomab

    CAS:
    <p>Catumaxomab is a rat-mouse hybrid lgG2 monoclonal and bispecific antibody that binds to the antigens CD3 and EpCAM for malignant ascites in cancer patients.</p>
    Purity:95%
    Color and Shape:Liquid

    Ref: TM-T78307

  • JAMM protein inhibitor 2 
    Targetmol
    + Info

    JAMM protein inhibitor 2 

    CAS:
    <p>JAMM inhibitor 2 targets thrombin, Rpn11, MMP2 with IC50s 10, 46, 89 μM, aids cancer research.</p>
    Formula:C21H26N2O2
    Purity:98.57%
    Color and Shape:Solid
    Molecular weight:338.44

    Ref: TM-T9892

  • CymitQuimica logo
    Targetmol
    + Info

    TFMU-ADPr triethylamine

    <p>TFMU-ADPr triethylamine is a substrate for PARG activity measurement, releasing a fluorophore to indicate PAR hydrolase activity.</p>
    Formula:C25H26F3N5O16P2·5C6H15N
    Color and Shape:Solid
    Molecular weight:1024.42

    Ref: TM-T74511

  • DNA31
    Targetmol
    + Info

    DNA31

    CAS:
    <p>DNA31 is a potent RNA polymerase inhibitor.</p>
    Formula:C48H58N4O13
    Purity:98%
    Color and Shape:Solid
    Molecular weight:898.99

    Ref: TM-T11068

  • CymitQuimica logo
    Targetmol
    + Info

    5'-O-DMTr-5-MedC (Ac)-methyl phosphonamidite

    <p>5’-O-DMTr-5-MedC (Ac)-methyl phosphonamidite, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies</p>
    Formula:C40H51N4O7P
    Color and Shape:Solid
    Molecular weight:730.83

    Ref: TM-T75201

  • CymitQuimica logo
    Targetmol
    + Info

    2'-Deoxy-2'-fluoro-N3-[(pyrid-2-yl)methyl]uridine

    <p>2’-Deoxy-2’-fluoro-N3-[(pyrid-2-yl)methyl]uridine, a uridine analogue, exhibits potential for antiepileptic applications.</p>
    Formula:C15H16FN3O5
    Color and Shape:Solid
    Molecular weight:337.3

    Ref: TM-T75080

  • CymitQuimica logo
    Targetmol
    + Info

    1-(β-D-Xylofuranosyl)-N6-Isopentenyladenine

    <p>1-(β-D-Xylofuranosyl)-N6-Isopentenyladenine is an adenosine analog.</p>
    Formula:C15H21N5O4
    Color and Shape:Solid
    Molecular weight:335.36

    Ref: TM-T75043

  • Guanosine 5'-triphosphate trisodium salt hydrate
    Targetmol
    + Info

    Guanosine 5'-triphosphate trisodium salt hydrate

    CAS:
    <p>5'-GTP trisodium salt hydrate activates G proteins and is a precursor for DNA/RNA synthesis.</p>
    Formula:C10H18N5NaO15P3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:564.185

    Ref: TM-T10178

  • YKL-5-124 TFA
    Targetmol
    + Info

    YKL-5-124 TFA

    CAS:
    <p>YKL-5-124 TFA is a potent CDK7 inhibitor (IC50: 53.5 nM), more than 100x selective over CDK9/2, not active on CDK12/13, and disrupts the cell cycle.</p>
    Formula:C30H34F3N7O5
    Color and Shape:Solid
    Molecular weight:629.63

    Ref: TM-T73633

  • CymitQuimica logo
    Targetmol
    + Info

    RNA polymerase II-IN-2

    <p>RNA Pol II-IN-2 (20iii) strongly inhibits Pol II (Ki=9.5 nM), is more toxic to CHO/HEK293 than α-amanitin.</p>
    Formula:C41H58N10O12S
    Color and Shape:Solid
    Molecular weight:915.02

    Ref: TM-T74631

  • SMS 121
    Targetmol
    + Info

    SMS 121

    CAS:
    <p>SMS 121 is a novel CD36 inhibitor that impairs fatty acid uptake and cell viability in acute myeloid leukaemia (AML) cells.</p>
    Formula:C20H21NO5
    Purity:98.29%
    Color and Shape:Soild
    Molecular weight:355.38

    Ref: TM-T205876

  • 6-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine
    Targetmol
    + Info

    6-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine

    CAS:
    <p>6-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine, a pyrimidine nucleoside analog, exhibits a broad spectrum of biochemical and</p>
    Formula:C11H15N5O4
    Color and Shape:Solid
    Molecular weight:281.27

    Ref: TM-T75185

  • HOE 33187-O-CONH-PEG4-phenol-thiophenone-NHPh-COOEt
    Targetmol
    + Info

    HOE 33187-O-CONH-PEG4-phenol-thiophenone-NHPh-COOEt

    CAS:
    <p>HOE 33187-O-CONH-PEG4-phenol-thiophenone-NHPh-COOEt inhibits pre-miR-21 RNA, potential for cancer research.</p>
    Formula:C57H62N8O10S
    Color and Shape:Solid
    Molecular weight:1051.21

    Ref: TM-T74244

  • CymitQuimica logo
    Targetmol
    + Info

    UnyLinker 12 TEA

    <p>UnyLinker 12 TEA is a versatile linker used in the synthesis of oligoribonucleotides.</p>
    Formula:C39H35NO10C6H15N
    Color and Shape:Solid
    Molecular weight:778.34655

    Ref: TM-TSW-00947

  • CymitQuimica logo
    Targetmol
    + Info

    Antibacterial agent 271

    <p>Antibacterialagent 271 is an antimicrobial compound that significantly inhibits Escherichia coli, with a minimum inhibitory concentration (MIC) of 2.2 μM. It disrupts bacterial membrane integrity, reducing metabolic activity. By binding to DNA grooves, it inhibits replication and induces reactive oxygen species (ROS) accumulation, leading to bacterial death. Antibacterialagent 271 shows considerable potential in combating bacterial infections.</p>
    Color and Shape:Odour Solid

    Ref: TM-T206586

  • Ac-MRGDH-NH2
    Targetmol
    + Info

    Ac-MRGDH-NH2

    <p>Ac-MRGDH-NH2 is a pentapeptide containing the RGD sequence. It is utilized in the synthesis of the diastereomeric prodrugs Λ- and Δ-[Ru(Ph2phen)2(κS,κN-(Ac-MRGDH-NH2))]Cl2. In these prodrugs, Ac-MRGDH-NH2 serves as a photolabile protecting group for the cytotoxic diruthenium aqua complexes [Ru(Ph2phen)2(OH2)2]2+, offering integrin targeting and photoactivation properties. Consequently, Ac-MRGDH-NH2 can be applied in studies exploring tumor-targeted photoactivatable chemotherapy.</p>
    Formula:C25H41N11O8S
    Color and Shape:Solid
    Molecular weight:655.727

    Ref: TM-TP3057

  • TAS-119
    Targetmol
    + Info

    TAS-119

    CAS:
    <p>TAS-119 (TAS-2104) is an orally available, selective and potent inhibitor of Aurora A with an IC50 of 1.0 nM.TAS-119 also inhibits Aurora B with an IC50 of 95</p>
    Formula:C23H22Cl2FN5O3
    Purity:99.65%
    Color and Shape:Solid
    Molecular weight:506.36

    Ref: TM-T34787

  • CymitQuimica logo
    Targetmol
    + Info

    GK13S

    <p>G13KS: UCHL1 ligand, deubiquitinase inhibitor; reduces monoubiquitin in glioblastoma cells.</p>
    Formula:C21H22N6O2
    Color and Shape:Solid
    Molecular weight:390.44

    Ref: TM-T75182

  • CDK9 ligand 3
    Targetmol
    + Info

    CDK9 ligand 3

    CAS:
    <p>CDK9ligand 3 is a ligand for CDK9 and can be utilized in the synthesis of PROTAC degraders, specifically PROTAC CDK9degrader-11.</p>
    Formula:C18H18BrCl2N5O3
    Color and Shape:Solid
    Molecular weight:503.177

    Ref: TM-T205690

  • CymitQuimica logo
    Targetmol
    + Info

    Farletuzumab

    CAS:
    <p>Farletuzumab (MORAb-003), a humanized antibody, inhibits FRα-expressing cell growth for cancer research.</p>
    Purity:> 95%
    Color and Shape:Liquid
    Molecular weight:145.36 kDa

    Ref: TM-T76720

  • CDK1-IN-2
    Targetmol
    + Info

    CDK1-IN-2

    CAS:
    <p>CDK1-IN-2 (cdk1 inhibitor 2) is a CDK1 inhibitor with IC50 of 5.8 μM.</p>
    Formula:C17H11ClN2O
    Purity:98.53%
    Color and Shape:Soild
    Molecular weight:294.73

    Ref: TM-T64373

  • KWR137
    Targetmol
    + Info

    KWR137

    <p>KWR137 is a WRN degrader with an IC50 of 8 nM. It exhibits significant antiproliferative activity against MSI-H cells, with a GI50 of 509 nM for SW48 cells and 824 μM for HCT116. Additionally, KWR137 demonstrates antitumor growth effects in xenograft mouse models. This compound is applicable for cancer research.</p>
    Formula:C33H31ClF3N9O4
    Color and Shape:Solid
    Molecular weight:710.105

    Ref: TM-T205674

  • CymitQuimica logo
    Targetmol
    + Info

    PROTAC CDK9 degrader-8

    <p>PROTAC CDK9 Degrader-8 (Compound 21) is a potent degrader of CDK9 with an IC50 of 0.01 μM, utilized in cancer research [1].</p>
    Formula:C44H52Cl2N10O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:903.85

    Ref: TM-T78928

  • CymitQuimica logo
    Targetmol
    + Info

    Subquinocin

    <p>Subquinocin is a CYLD inhibitor that suppresses deubiquitinating enzymes (DUB) of the USP family. By inhibiting CYLD, Subquinocin enhances the activation of the NF-κB and IFN pathways. Additionally, Subquinocin facilitates the activation of IRF3 and/or IRF7 in the RIG-I-mediated interferon pathway.</p>
    Formula:C20H27N3O4S
    Color and Shape:Solid
    Molecular weight:405.17223

    Ref: TM-T207399

  • CymitQuimica logo
    Targetmol
    + Info

    5'-O-DMTr-2',2'-difluoro-dC(Bz)-methyl phosphonamidite

    <p>5’-O-DMTr-2’,2’-difluoro-dC(Bz)-methyl phosphonamidite is a purine nucleoside analog with extensive antitumor activity against indolent lymphoid malignancies.</p>
    Formula:C44H49F2N4O7P
    Color and Shape:Solid
    Molecular weight:814.85

    Ref: TM-T75190

  • Chk1-IN-6
    Targetmol
    + Info

    Chk1-IN-6

    CAS:
    <p>Chk1-IN-6 is a potent, selective, and orally bioavailable CHK1 inhibitor candidate.</p>
    Formula:C16H18F3N7
    Color and Shape:Solid
    Molecular weight:365.364

    Ref: TM-T40091

  • (E/Z)-THZ1 2HCl
    Targetmol
    + Info

    (E/Z)-THZ1 2HCl

    CAS:
    <p>THZ1 2HCl: selective CDK7 allosteric inhibitor, IC50 3.2 nM, hinders cancer cell growth.</p>
    Formula:C31H30Cl3N7O2
    Purity:99.51%
    Color and Shape:Solid
    Molecular weight:638.98

    Ref: TM-T35332

  • α2β1 Integrin Ligand Peptide
    Targetmol
    + Info

    α2β1 Integrin Ligand Peptide

    CAS:
    <p>The Asp-Gly-Glu-Ala (DGEA) amino acid domain of type I collagen interacts with the α2β1 integrin receptor on the cell membrane and mediates extracellular</p>
    Formula:C14H22N4O9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:390.35

    Ref: TM-TP1484

  • Clofarabine-5'-diphosphate
    Targetmol
    + Info

    Clofarabine-5'-diphosphate

    CAS:
    <p>Clofarabine-5'-diphosphate (Clofarabine-DP) is a metabolite resulting from the phosphorylation of Clofarabine by deoxycytidine kinase (dCK). It can undergo further phosphorylation to become Clofarabine-5'-triphosphate, exhibiting cytotoxicity in cancer cells by inhibiting DNA synthesis and repair.</p>
    Formula:C10H13ClFN5O9P2
    Color and Shape:Solid
    Molecular weight:463.64

    Ref: TM-T203181

  • CymitQuimica logo
    Targetmol
    + Info

    N4-(3,3,3-Trifluoropropanoyl)cytidine

    <p>N4-(3,3,3-Trifluoropropanoyl)cytidine, a cytidine analog, inhibits DNA methyltransferases, possibly anti-metabolic and anti-cancer.</p>
    Formula:C12H14F3N3O6
    Color and Shape:Solid
    Molecular weight:353.25

    Ref: TM-T75194

  • Isocytosine
    Targetmol
    + Info

    Isocytosine

    CAS:
    <p>Compound PDK0016, with CAS No. 108-53-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0016 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>
    Formula:C4H5N3O
    Color and Shape:White To Off-White Solid
    Molecular weight:111.1

    Ref: TM-PDK0016

  • T-2513
    Targetmol
    + Info

    T-2513

    CAS:
    <p>T-2513 inhibits topoisomerase I by covalently bonding to its DNA complex, blocking DNA replication and causing cell death.</p>
    Formula:C25H27N3O5
    Color and Shape:Solid
    Molecular weight:449.507

    Ref: TM-T40365

  • CCT241533 dihydrochloride
    Targetmol
    + Info

    CCT241533 dihydrochloride

    CAS:
    <p>Potent Chk2 inhibitor with 3 nM IC50, 63-fold more selective over Chk1, affects 84 kinases, reduces DNA damage response and apoptosis in cells.</p>
    Formula:C23H29Cl2FN4O4
    Color and Shape:Solid
    Molecular weight:515.41

    Ref: TM-T36704

  • Carboxy pyridostatin trifluoroacetate salt
    Targetmol
    + Info

    Carboxy pyridostatin trifluoroacetate salt

    <p>Carboxy pyridostatin trifluoroacetate salt exhibits higher molecular specificity for RNA over DNA G4s.</p>
    Formula:C37H35F3N10O9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:820.73

    Ref: TM-T13595

  • CymitQuimica logo
    Targetmol
    + Info

    PD-1/PD-L1-IN-51

    <p>PD-1/PD-L1-IN-51 (Compound III-4) is an inhibitor of PD-1/PD-L1 (IC50: hPD-L1 at 2.9 nM). It binds directly to PD-L1, blocking the interaction between PD-1 and PD-L1, and enhancing the release of IFN-γ. Additionally, PD-1/PD-L1-IN-51 exhibits antitumor activity.</p>
    Color and Shape:Odour Solid

    Ref: TM-T200579

  • Py-MAA-Val-Cit-PAB-DX8951
    Targetmol
    + Info

    Py-MAA-Val-Cit-PAB-DX8951

    CAS:
    <p>Py-MAA-Val-Cit-PAB-DX8951, a purine toxin, serves as an intermediate in the synthesis of antibody-drug conjugates [1].</p>
    Formula:C57H66FN11O13S
    Color and Shape:Solid
    Molecular weight:1164.26

    Ref: TM-T75117

  • CymitQuimica logo
    Targetmol
    + Info

    Mps1-IN-6

    <p>Mps1-IN-6 is a potent Mps1 inhibitor that demonstrates antiproliferative and antitumor activities, exhibiting an IC50 of 2.596 nM [1].</p>
    Formula:C35H39N9O3
    Color and Shape:Solid
    Molecular weight:633.74

    Ref: TM-T78965

  • CymitQuimica logo
    Targetmol
    + Info

    2'-O-Methyladenosine 5'-monophosphate triethyl ammonium

    <p>2’-O-Methyladenosine 5’-monophosphate triethyl ammonium is an adenosine analog.</p>
    Formula:C11H14N5O7P2
    Color and Shape:Solid
    Molecular weight:359.23

    Ref: TM-T75196

  • Apcin A HCL
    Targetmol
    + Info

    Apcin A HCL

    CAS:
    <p>Apcin A HCL is an Apcin-derived APC inhibitor that binds Cdc20 and hinders ubiquitination, useful for synthesizing PROTAC CP5V.</p>
    Formula:C10H15Cl4N5O2
    Purity:99.59%
    Color and Shape:Solid
    Molecular weight:379.07

    Ref: TM-T64339

  • 5'-O-DMT-N4-Bz-2'-F-dC
    Targetmol
    + Info

    5'-O-DMT-N4-Bz-2'-F-dC

    CAS:
    <p>5’-O-DMT-N4-Bz-2’-F-dC is a nucleoside with protective and modification effects.</p>
    Formula:C37H34FN3O7
    Color and Shape:Solid
    Molecular weight:651.68

    Ref: TM-T37137

  • m7GpppCmpG
    Targetmol
    + Info

    m7GpppCmpG

    CAS:
    <p>m7GpppCmpG, a trinucleotide cap analogue, enables RNA manufacturing with cap 0 or cap 1 structures.</p>
    Formula:C31H43N13O25P4
    Color and Shape:Solid
    Molecular weight:1121.64

    Ref: TM-T74481

  • Xanthosine-5'-Triphosphate
    Targetmol
    + Info

    Xanthosine-5'-Triphosphate

    CAS:
    <p>Xanthosine-5'-Triphosphate (5'-XTP), a nucleotide derived from the deamination of purine bases, plays a crucial role in various biological processes.</p>
    Formula:C10H15N4O15P3
    Color and Shape:Solid
    Molecular weight:524.164

    Ref: TM-T40714

  • GS-443902 trisodium
    Targetmol
    + Info

    GS-443902 trisodium

    CAS:
    <p>GS-443902 trisodium, a strong RdRp blocker, inhibits RSV/HCV with IC50 of 1.1/5 μM and is Remdesivir's active form.</p>
    Formula:C12H16N5O13P3·xNa
    Color and Shape:Solid

    Ref: TM-T38761

  • PROTAC CDK9 degrader 4
    Targetmol
    + Info

    PROTAC CDK9 degrader 4

    CAS:
    <p>PROTAC CDK9 degrader 4 is a CDK9 degrader that targets transcriptional regulation and has potential anticancer activity.</p>
    Formula:C43H56N10O5
    Color and Shape:Solid
    Molecular weight:792.97

    Ref: TM-T39996