Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase(114 products)
- CDK(543 products)
- Cell Cycle Arrest(5 products)
- Chk(47 products)
- DYRK(48 products)
- Dynamin(27 products)
- Ferroptosis(226 products)
- HSP(179 products)
- Integrin(228 products)
- Kinesin(88 products)
- LIM Kinase(20 products)
- Microtubule Associated(274 products)
- PKC(119 products)
- PLK(25 products)
- ROCK(63 products)
- Rho(5 products)
- Wee1(14 products)
- c-Myc(76 products)
Show 10 more subcategories
Found 3826 products of "Cell Cycle/Checkpoint"
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Belumosudil mesylate
CAS:Belumosudil mesylate (KD025 mesylate) is a ROCK2 inhibitor with antifibrotic activity, and can be used in chronic graft-versus-host disease research.Formula:C27H28N6O5SPurity:98.73%Color and Shape:SolidMolecular weight:548.61Ref: TM-T39555
1mg34.00€2mg46.00€5mg71.00€10mg96.00€25mg155.00€50mg230.00€100mg353.00€200mg517.00€1mL*10mM (DMSO)85.00€Maleic hydrazide
CAS:Maleic hydrazide is a plant germination inhibitor that participates in nucleic acid metabolism pathways ,inhibiting cell division in the apical meristem.Formula:C4H4N2O2Purity:98.4%Color and Shape:Crystals From Water Maleic Hydrazide Is An Odorless White Solid Sinks In Water (Uscg 1999)Molecular weight:112.09N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite
CAS:N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite is an adenine nucleoside analog with potential vasodilator activity and anticancer activity.Formula:C47H52N7O7PPurity:97.36%Color and Shape:SolidMolecular weight:857.932'-O-Methylinosine
CAS:2'-O-Methylinosine (2'-(o-Methyl)-inosine) is an orally bioavailable purine nucleoside analog with antihypertensive activity.Formula:C11H14N4O5Purity:99.88%Color and Shape:SolidMolecular weight:282.252',5-Difluoro-2'-deoxy-1-arabinosyluracil
CAS:2',5-Difluoro-2'-deoxy-1-arabinosyluracil (2'-Deoxy-2'-fluoro-5-fluoro-arabinouridine) is a urinary pyrimidine nucleoside analogue with potential antiepilepticFormula:C9H10F2N2O5Purity:99.99%Color and Shape:SolidMolecular weight:264.18NU6102
CAS:NU6102 is a CDK2 inhibitor with antitumor activity against CDK1/cyclinB, CDK1/CDK2, CDK4, DYRK1A , PDK1, and ROCKII, and it can be used to study rectal cancer.Formula:C18H22N6O3SPurity:99.76%Color and Shape:SolidMolecular weight:402.47LDC4297
CAS:LDC4297 (LDC044297) is a potent and selective CDK7 inhibitor.Formula:C23H28N8OPurity:98.25%Color and Shape:SolidMolecular weight:432.52GW406108X
CAS:GW406108X is a Kif15 and ULK1 inhibitor; IC50: 0.82 µM (ATPase), pIC50: 6.37; blocks autophagy.Formula:C20H11Cl2NO4Purity:98%Color and Shape:SolidMolecular weight:400.21IRES-C11
CAS:IRES-C11 is a specific inhibitor of translation that targets the internal ribosome entry site (IRES) of the c-MYC gene. It functions by blocking the interaction between heterogeneous nuclear ribonucleoprotein A1, a trans-acting factor required for c-MYC IRES activity, and its corresponding IRES. Notably, IRES-C11 does not inhibit the IRES activity of BAG-1, XIAP, and p53.Formula:C13H11Cl2NO4Purity:99.89%Color and Shape:SolidMolecular weight:316.14Ref: TM-T40419
1mg94.00€5mg222.00€10mg356.00€25mg708.00€50mg1,063.00€100mg1,674.00€200mg2,242.00€1mL*10mM (DMSO)245.00€Poloxime
CAS:Poloxime is a hydrolysis product of poloxin and is a non-ATP-competitive Plk1 inhibitor. It also has moderate Plk1 inhibitory activity.Formula:C10H13NO2Purity:98%Color and Shape:SolidMolecular weight:179.22TAME
CAS:Tosyl-L-Arginine Methyl Ester (TAME (N-4-Tosyl-L-arginine methyl ester)) is an APC inhibitor.Formula:C14H22N4O4SPurity:98%Color and Shape:SolidMolecular weight:342.41Cilengitide TFA
CAS:Cilengitide, αvβ3/αvβ5 inhibitor, IC50: 4.1/79 nM in vitro. 10x selectivity vs. gpIIbIIIa. Phase 2.Formula:C29H41F3N8O9Color and Shape:SolidMolecular weight:702.68Nolatrexed dihydrochloride
CAS:Nolatrexed dihydrochloride (Thymitaq) is a soluble, lipophilic cancer drug that inhibits DNA replication, causing cell cycle arrest and apoptosis.Formula:C14H14Cl2N4OSPurity:97.02%Color and Shape:Tan SolidMolecular weight:357.26CCT244747
CAS:CCT244747 is a potent and selective CHK1 inhibitor oral, ATP-competitive, and cytotoxic, abrogating drug-induced S and G2 blockade and inducing apoptosis .Formula:C20H24N8O2Purity:99.17%Color and Shape:SolidMolecular weight:408.46Ribociclib hydrochloride
CAS:Ribociclib hydrochloride (LEE011 HCl) is a selective, orally active cyclin-dependent kinase CDK4/6 inhibitor (IC50=10/39 nM) that inhibits proliferation.Formula:C23H31ClN8OPurity:99.87%Color and Shape:SolidMolecular weight:471sAJM589
CAS:sAJM589 is a Myc inhibitor that dose-dependently disrupts Myc-Max heterodimers, thereby decreasing Myc protein levels and inhibiting the cellular proliferation.Formula:C16H10N2OPurity:98%Color and Shape:SolidMolecular weight:246.26Synucleozid hydrochloride
CAS:Synucleozid hydrochloride inhibits the translation of the intrinsically disordered protein α-synuclein by targeting its structured mRNA.Formula:C22H21ClN6Purity:98.13%Color and Shape:SolidMolecular weight:404.9N,N-Dimethyl-2'-O-methylcytidine
CAS:N,N-Dimethyl-2'-O-methylcytidine (N4, N4, 2'-O-Trimethylcytidine) is a purine nucleoside analogue with anti-cancer activity.Formula:C12H19N3O5Purity:99.62%Color and Shape:SolidMolecular weight:285.38-Chloroinosine
CAS:8-Chloroinosine is a purine nucleoside analog and a metabolite of the anticancer compound 8-chloro-adenosine.Formula:C10H11ClN4O5Purity:99.37% - 99.56%Color and Shape:SolidMolecular weight:302.67Kinesore
CAS:Kinesore is a cell-permeable modulator that binds to the microtubule motor protein kinesin-1, thereby inhibiting the interaction between KLC2 and SKIP.Formula:C20H16Br2N4O4Purity:97.24%Color and Shape:SolidMolecular weight:536.17Ref: TM-T15663
2mg42.00€5mg63.00€10mg90.00€25mg163.00€50mg237.00€100mg356.00€200mg526.00€1mL*10mM (DMSO)75.00€
