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Cell Cycle/Checkpoint

Cell Cycle/Checkpoint

Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.

Subcategories of "Cell Cycle/Checkpoint"

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Found 3739 products of "Cell Cycle/Checkpoint"

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  • GS-443902 trisodium

    CAS:
    <p>GS-443902 trisodium, a strong RdRp blocker, inhibits RSV/HCV with IC50 of 1.1/5 μM and is Remdesivir's active form.</p>
    Formula:C12H16N5O13P3·xNa
    Color and Shape:Solid
  • PLK1-IN-2

    CAS:
    PLK1-IN-2 is a PLK1 kinase inhibitor with an IC 50 value of 0.384 μM.
    Formula:C24H27FN8OS
    Color and Shape:Solid
    Molecular weight:494.59
  • 5'-O-DMT-Bz-rC

    CAS:
    <p>5’-O-DMT-Bz-Rc is a modified nucleoside and can be used to synthesize DNA or RNA.</p>
    Formula:C37H35N3O8
    Color and Shape:Solid
    Molecular weight:649.69
  • Uridine-5-oxo-acetyl-(9-fluorenylmethyl) ester


    Uridine analogue with antitumor effects; inhibits DNA synthesis, induces apoptosis in lymphoid cancers.
    Formula:C24H24N2O9
    Color and Shape:Solid
    Molecular weight:484.46
  • Heliquinomycin

    CAS:
    Heliquinomycin, a Streptomyces metabolite, inhibits DNA helicase (Ki=6.8 μM) and fights Gram-positive bacteria and various cancer cells.
    Formula:C33H30O17
    Color and Shape:Solid
    Molecular weight:698.586
  • 3'-Deoxyuridine-5'-triphosphate trisodium


    3'-dUTP trisodium, a nucleotide analogue, inhibits RNA polymerases I/II and UTP integration into RNA (Ki=2.0 μM).
    Formula:C9H12N2Na3O14P3
    Color and Shape:Soild
    Molecular weight:534.08
  • (1S,3R,5R)-PIM447 dihydrochloride


    <p>(1S,3R,5R)-PIM447 (dihydrochloride) an inhibitor of PIM(IC50 of 0.095 μM for Pim1, 0.522 μM for Pim2 and 0.369 μM for Pim3).</p>
    Formula:C24H25Cl2F3N4O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:513.38
  • GK13S


    <p>G13KS: UCHL1 ligand, deubiquitinase inhibitor; reduces monoubiquitin in glioblastoma cells.</p>
    Formula:C21H22N6O2
    Color and Shape:Solid
    Molecular weight:390.44
  • Chrysomycin A

    CAS:
    Chrysomycin A is an antibiotic that can be derived from Streptomyces.
    Formula:C28H28O9
    Color and Shape:Solid
    Molecular weight:508.52
  • UnyLinker 12 TEA


    UnyLinker 12 TEA is a versatile linker used in the synthesis of oligoribonucleotides.
    Formula:C39H35NO10C6H15N
    Color and Shape:Solid
    Molecular weight:778.34655
  • Anti-EMMPRIN/CD147 Antibody


    Anti-EMMPRIN/CD147 Antibody is a human-derived antibody expressed in CHO cells, targeting Basigin. For an isotype control, refer to HumanIgG1kappa, Isotype Control.
    Color and Shape:Odour Liquid
  • JB300

    CAS:
    JB300 is a PROTAC-based compound that serves as a highly selective degrader of Aurora A, with a DC50 of 30 nM. It is utilized in cancer research. JB300 comprises the PROTAC target protein ligand MK-5108 [pink part], E3 ligase ligand Thalidomide-O-COOH [blue part], and PROTAC Linker Boc-NH-PEG2-C2-NH2 [black part]. The conjugate of the E3 ubiquitin ligase ligand and linker is Thalidomide-O-COOH-NH2-C2-PEG2-NH-Boc.
    Formula:C43H45ClFN7O10S
    Color and Shape:Solid
    Molecular weight:906.375
  • Lorutengitide

    CAS:
    <p>Lorutengitide is a transcription-regulating peptide with antiproliferative activity.</p>
    Formula:C30H50N8O12
    Color and Shape:Solid
    Molecular weight:714.764
  • m7GpppCpG

    CAS:
    <p>m7GpppCpG, a trinucleotide cap analogue, is used for synthesizing RNA with cap 0 or cap 1 structures.</p>
    Formula:C30H41N13O25P4
    Color and Shape:Solid
    Molecular weight:1107.61
  • Carboxy pyridostatin trifluoroacetate salt


    Carboxy pyridostatin trifluoroacetate salt exhibits higher molecular specificity for RNA over DNA G4s.
    Formula:C37H35F3N10O9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:820.73
  • 5'-O-TBDMS-dA

    CAS:
    <p>5’-O-TBDMS-dA is a modified nucleoside and can be used to synthesize DNA or RNA.</p>
    Formula:C16H27N5O3Si
    Color and Shape:Solid
    Molecular weight:365.509
  • Anticancer agent 263


    Anticanceragent 263 (compound 7) is an effective anticancer agent. It binds with the G-quadruplex DNA (G4) sequence 22-mer Pu22 (a c-Myc DNA analog). As a structural modulator, Anticanceragent 263 significantly enhances the formation of protein α-helices and has the capacity to form a supramolecular network. Furthermore, Anticanceragent 263 exhibits no cytotoxicity.
    Formula:C13H20N2O6
    Color and Shape:Solid
    Molecular weight:300.308
  • WAY-647802

    CAS:
    <p>WAY-647802 is a CDK inhibitor.</p>
    Formula:C11H14N4O3
    Purity:99.53%
    Color and Shape:Solid
    Molecular weight:250.25
  • Obtustatin


    <p>Potent α1β1 integrin inhibitor, 0.8 nM IC50 for IV collagen binding. Selective over other integrins. Inhibits FGF2 angiogenesis; antitumor in mouse models.</p>
    Formula:C184H284N52O57S8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:4393.07
  • 5-Methylcytidine 5′-triphosphate

    CAS:
    5-Methylcytidine 5′-triphosphate (5-Methyl-CTP), a modified nucleoside triphosphate, enhances translational properties and stability while reducing innate
    Formula:C10H18N3O14P3
    Color and Shape:Solid
    Molecular weight:497.18