CymitQuimica logo
Cell Cycle/Checkpoint

Cell Cycle/Checkpoint

Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.

Subcategories of "Cell Cycle/Checkpoint"

Show 10 more subcategories

Found 3739 products of "Cell Cycle/Checkpoint"

Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • 2'-F-CDP
    Targetmol
    + Info

    2'-F-CDP

    CAS:
    2'-F-CDP is a nucleotide analog that can be utilized in the synthesis of oligonucleotides.
    Formula:C9H14FN3O10P2
    Color and Shape:Solid
    Molecular weight:405.17

    Ref: TM-TSW-00957

  • Deoxythymidine-5'-triphosphate-d15
    Targetmol
    + Info

    Deoxythymidine-5'-triphosphate-d15

    CAS:
    Deoxythymidine-5'-triphosphate-d15 (dTTP-d15) dilithium is a deuterium-labeled form of deoxythymidine-5'-triphosphate. Deoxythymidine-5'-triphosphate (dTTP) is a triphosphate nucleotide utilized in DNA synthesis.
    Formula:C10H15Li2N2O14P3
    Color and Shape:Solid
    Molecular weight:509.13

    Ref: TM-T211806

  • AGH-107
    Targetmol
    + Info

    AGH-107

    CAS:
    AGH-107 is a highly selective 5-HT7 receptor agonist that can cross the blood-brain barrier, featuring a Ki value of 6 nM and an EC50 value of 19 nM. Demonstrating high selectivity for central nervous system targets, AGH-107 also exhibits high metabolic stability and low toxicity in HEK-293 and HepG2 cell cultures.
    Formula:C13H12IN3
    Color and Shape:Solid
    Molecular weight:337.16

    Ref: TM-T201735

  • 3'-NH-Tr-2',3'-ddG(iBu)-5'-CE-Phosphoramidite
    Targetmol
    + Info

    3'-NH-Tr-2',3'-ddG(iBu)-5'-CE-Phosphoramidite

    CAS:
    3'-NH-Tr-2',3'-ddG(iBu)-5'-CE-Phosphoramidite is a nucleoside phosphoramidite monomer featuring protective group modifications, suitable for RNA oligonucleotide synthesis.
    Formula:C42H51N8O5P
    Color and Shape:Solid
    Molecular weight:778.88

    Ref: TM-TSW-01143

  • LNA-UTP
    Targetmol
    + Info

    LNA-UTP

    CAS:
    LNA-UTP is a nucleotide analogue used in the synthesis of oligonucleotides.
    Formula:C10H15N2O15P3
    Color and Shape:Solid
    Molecular weight:496.15

    Ref: TM-TSW-00943

  • YKL-1-116
    Targetmol
    + Info

    YKL-1-116

    CAS:
    YKL-1-116 is an effective, selective, and covalent CDK7 inhibitor.
    Formula:C34H38N8O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:606.72

    Ref: TM-T24643

  • Mitotic kinesin-IN-1 hydrochloride
    Targetmol
    + Info

    Mitotic kinesin-IN-1 hydrochloride

    CAS:
    Mitotic kinesin-IN-1 hydrochloride (Example 80) is an inhibitor of mitotic kinesin, which suppresses cell proliferation by hindering mitosis. This compound is applicable in research related to cancer, cardiac hypertrophy, immune and inflammatory diseases, and fungal infections.
    Formula:C22H26ClF2N3OS
    Color and Shape:Solid
    Molecular weight:453.98

    Ref: TM-T212561

  • CymitQuimica logo
    Targetmol
    + Info

    Anticancer agent 30

    <p>Anticancer agent 30 (6f-Z), a 3-arylidene-2-oxindole, selectively inhibits CDK2, showing potent anticancer potential.</p>
    Formula:C22H15ClFNO
    Color and Shape:Solid
    Molecular weight:363.81

    Ref: TM-T61379

  • (R)-Atuveciclib
    Targetmol
    + Info

    (R)-Atuveciclib

    CAS:
    Atuveciclib (BAY-1143572) is a potent and highly selective, oral PTEFb / CDK9 inhibitor that inhibits CDK9 / CycT1 with an IC 50 of 13 nM [1].
    Formula:C18H18FN5O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:387.43

    Ref: TM-T10464

  • LNA-GTP
    Targetmol
    + Info

    LNA-GTP

    CAS:
    LNA-GTP is a nucleotide analog used in the synthesis of oligonucleotides.
    Formula:C11H16N5O14P3
    Color and Shape:Solid
    Molecular weight:535.19

    Ref: TM-TSW-00969

  • AB25583
    Targetmol
    + Info

    AB25583

    CAS:
    AB25583 is a small molecule inhibitor of Polθ helicase (Polθ-hel) with an IC50 of 6 nM. It selectively kills cells deficient in BRCA1/2 and synergizes with Olaparib in cancer cells harboring pathogenic BRCA1/2 mutations. AB25583 can be utilized in tumor research.
    Formula:C22H17ClN4O3S
    Color and Shape:Solid
    Molecular weight:452.91

    Ref: TM-T200101

  • CymitQuimica logo
    Targetmol
    + Info

    Dyrk1A-IN-1

    Dyrk1A-IN-1 is a triple inhibitor of Dyrk1A kinase activity, aggregation of tau and α-syn oligomers, with an IC50 value of 119 nM for Dyrk1A kinase.
    Formula:C23H20N4O3S
    Color and Shape:Solid
    Molecular weight:432.49

    Ref: TM-T62414

  • (E)-Antiviral agent 67
    Targetmol
    + Info

    (E)-Antiviral agent 67

    CAS:
    <p>(E)-Antiviral agent 67 (compound PC6) is a pyrazolone-based antiviral compound that exhibits inhibitory activity against RNA-dependent RNA polymerase.</p>
    Formula:C19H19N3O
    Color and Shape:Solid
    Molecular weight:305.374

    Ref: TM-T206106

  • 2'-O-MOE-UTP
    Targetmol
    + Info

    2'-O-MOE-UTP

    CAS:
    2'-O-MOE-UTP is a nucleotide analog employed in the synthesis of oligonucleotides.
    Formula:C12H21N2O16P3
    Color and Shape:Solid
    Molecular weight:542.22

    Ref: TM-TSW-00959

  • P162-0948
    Targetmol
    + Info

    P162-0948

    CAS:
    P162-0948 is a selective CDK8 inhibitor with an IC50 value of 50.4 nM. It reduces cell migration and the expression of EMT-related proteins in the A549 human alveolar epithelial cell line. Furthermore, P162-0948 decreases Smad phosphorylation, indicating disruption of the TGF-β/Smad signaling pathway, making it a promising compound for pulmonary fibrosis research.
    Formula:C20H15FN4O2
    Color and Shape:Solid
    Molecular weight:362.357

    Ref: TM-T205592

  • CDK4/9-IN-1
    Targetmol
    + Info

    CDK4/9-IN-1

    CAS:
    CDK4/9-IN-1 (Compound 29) is a selective dual inhibitor of CDK4 and CDK9, exhibiting IC50 values of 23 nM and 12 nM, respectively. It holds potential for use in cancer research.
    Formula:C22H34N6O2
    Color and Shape:Solid
    Molecular weight:414.544

    Ref: TM-T205312

  • MKLP2-IN-1
    Targetmol
    + Info

    MKLP2-IN-1

    CAS:
    <p>MKLP2-IN-1 (compound 12a) is an inhibitor of MKLP2 that demonstrates excellent oral bioactivity. In vitro, MKLP2-IN-1 inhibits the ATPase activity stimulated by recombinant MKLP2 microtubules and, in a mouse Calu-6 lung cancer model, it effectively suppresses tumor growth.</p>
    Formula:C23H19BrFN3O2
    Color and Shape:Solid
    Molecular weight:468.318

    Ref: TM-T205538

  • CDK2-IN-39
    Targetmol
    + Info

    CDK2-IN-39

    CAS:
    <p>CDK2-IN-39 (compound 4) is a CDK2 inhibitor.</p>
    Formula:C14H15N3O4S
    Color and Shape:Solid
    Molecular weight:321.352

    Ref: TM-T204890

  • CDK2-IN-40
    Targetmol
    + Info

    CDK2-IN-40

    CAS:
    CDK9-IN-40 is an inhibitor of CDK2 (Cyclin-dependent kinase 2). It effectively inhibits CDK2/Cyclin E1, with an IC50 of ≤ 10 nM.
    Formula:C16H21N7O2
    Color and Shape:Solid
    Molecular weight:343.384

    Ref: TM-T205452

  • MU147
    Targetmol
    + Info

    MU147

    CAS:
    MU147 is an MRE11 nuclease inhibitor and chemical probe with anticancer properties, exhibiting lethal effects on Ehrlich ascites tumor cells both in vivo and in vitro. It disrupts the MRE11 nuclease-dependent double-strand break repair mechanism without impairing ATM activation. Additionally, MU147 damages the degradation of nascent strands at stalled replication forks and selectively affects BRCA2-deficient cells.
    Formula:C19H13N3O3S
    Color and Shape:Solid
    Molecular weight:363.39

    Ref: TM-T205293