CymitQuimica logo
Cell Cycle/Checkpoint

Cell Cycle/Checkpoint

Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.

Subcategories of "Cell Cycle/Checkpoint"

Show 10 more subcategories

Found 3739 products of "Cell Cycle/Checkpoint"

Sort by

Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • Fradafiban

    CAS:
    Fradafiban binds to the human platelet GP IIb/IIIa complex with a Kd value of 148 nM. Fradafiban is a non-polypeptide platelet glycoprotein IIb/IIIa antagonist.
    Formula:C20H21N3O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:367.40
  • 3'-NH2-CTP

    CAS:
    3'-NH2-CTP is a nucleotide analog modified with an amino group at the 3' position of CTP.
    Formula:C9H17N4O13P3
    Color and Shape:Solid
    Molecular weight:482.17
  • 12(S)-HETE

    CAS:
    <p>Enpatoran hydrochloride (M5049 hydrochloride) is a TLR7/8 inhibitor with antiviral activity that is used in the study of autoimmune diseases.</p>
    Formula:C20H32O3
    Color and Shape:Solid
    Molecular weight:320.47
  • (R)-CSN5i-3

    CAS:
    (R)-CSN5i-3 is CSN5i-3 of the R configuration.
    Formula:C28H29F2N5O2
    Purity:99.76% - 99.97%
    Color and Shape:Solid
    Molecular weight:505.56
  • Eprociclovir Na

    CAS:
    Eprociclovir Na (A-5021) is 15x stronger than acyclovir at inhibiting herpesviruses, showing promise for EHV1 and herpetic keratitis treatment.
    Formula:C11H14N5NaO3
    Color and Shape:Solid
    Molecular weight:287.25
  • Anticancer agent 29


    <p>Compound E/Z-6f, anticancer, IC50: CDK2 (0.054 μM), CDK1 (0.127 μM), CDK4 (0.129 μM), CDK6 (0.396 μM).</p>
    Formula:C22H15ClFNO
    Color and Shape:Solid
    Molecular weight:363.81
  • Dyrk1A/α-synuclein-IN-2


    Dyrk1A/α-synuclein-IN-2 (Compound b20) is a dual inhibitor of Dyrk1A and α-synuclein aggregation that acts on α-synuclein (IC50: 7.8 μM).
    Formula:C21H16N4O4S
    Color and Shape:Solid
    Molecular weight:420.44
  • LNA-CTP

    CAS:
    <p>LNA-CTP is a nucleotide analog utilized in the synthesis of oligonucleotides.</p>
    Formula:C10H16N3O14P3
    Color and Shape:Solid
    Molecular weight:495.17
  • IXA62

    CAS:
    IXA62 is an orally active, selective IRE1/XBP1s agonist (EC50= 0.31 μM) that can reduce Aβ secretion.
    Formula:C24H23N3O3
    Color and Shape:Solid
    Molecular weight:401.458
  • DHX9-IN-19

    CAS:
    <p>DHX9-IN-19 (compound 3) is an orally active inhibitor of DHX9, playing a significant role in cancer research.</p>
    Formula:C20H21ClN4O4S2
    Color and Shape:Solid
    Molecular weight:480.988
  • L 734217

    CAS:
    L 734217 is an antagonist of the fibrinogen receptor.
    Formula:C18H31N3O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:353.46
  • Dyrk1A-IN-4

    CAS:
    Dyrk1A-IN-4, compound 48, is an oral DYRK1A/DYRK2 inhibitor with IC50s: 2 nM (DYRK1A), 6 nM (DYRK2), anticancer properties.
    Formula:C14H13F3N6
    Color and Shape:Solid
    Molecular weight:322.29
  • Cdc7-IN-19

    CAS:
    Cdc7-IN-19 (compound 1-1) is a potent CDC7 inhibitor with an IC 50 of 1.49 nM [1].
    Formula:C19H21N5O2
    Color and Shape:Solid
    Molecular weight:351.40
  • Cdc7-IN-18

    CAS:
    <p>Cdc7-IN-18 (1-2) inhibits CDC7 enzyme (IC50: 1.29 nM) and COLO205 cell proliferation (IC50: 53.62 nM).</p>
    Formula:C19H21N5OS
    Color and Shape:Solid
    Molecular weight:367.47
  • GR 83895

    CAS:
    GR 83895 is an antagonist of prototype fibrinogen receptor.
    Formula:C29H39N9O8S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:673.74
  • Polθ-IN-7

    CAS:
    <p>Polθ-IN-7 (example 12) is an inhibitor of DNA polymerase θ (Polθ) with a Ki of 1.27 nM.</p>
    Formula:C28H35F3N6O2
    Color and Shape:Solid
    Molecular weight:544.612
  • 3'-Deoxy-GTP

    CAS:
    <p>3'-Deoxy-GTP (3′-Deoxyguanosine 5′-triphosphate) is an analog of GTP and serves as an RNA chain terminator, effectively inhibiting RNA synthesis. It can inhibit dengue virus DENV NS5 RdRp with an IC50 of 0.02 μM.</p>
    Formula:C10H16N5O13P3
    Color and Shape:Solid
    Molecular weight:507.181
  • ROCK-IN-11

    CAS:
    ROCK-IN-11 (example 94) is an effective inhibitor of ROCK1 and ROCK2, with an IC50 of ≤ 5 μM, and plays a significant role in cancer research.
    Formula:C22H20N4O4S
    Color and Shape:Solid
    Molecular weight:436.484
  • isoGTP lithium

    CAS:
    isoGTP (Isoguanosine-5'-triphosphate) lithium is a GTP analog.
    Formula:C10H12Li4N5O14P3
    Color and Shape:Solid
    Molecular weight:546.91
  • CDK8-IN-14

    CAS:
    <p>CDK8-IN-14 (compound 12) effectively inhibits CDK8, demonstrating an IC50 of 39.2 nM, and exhibits potent anti-AML cell proliferation effects, with a GC50 value of 0.02±0.01μM in MOLM-13 cells and 0.03±0.01μM in MV4-11 cells [1].</p>
    Formula:C18H13N3O2
    Color and Shape:Solid
    Molecular weight:303.31