Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase(109 products)
- CDK(522 products)
- Cell Cycle Arrest(4 products)
- Chk(46 products)
- DYRK(49 products)
- Dynamin(26 products)
- Ferroptosis(223 products)
- HSP(179 products)
- Integrin(256 products)
- Kinesin(83 products)
- LIM Kinase(19 products)
- Microtubule Associated(284 products)
- PKC(111 products)
- PLK(25 products)
- ROCK(67 products)
- Rho(2 products)
- Wee1(14 products)
- c-Myc(74 products)
Show 10 more subcategories
Found 3730 products of "Cell Cycle/Checkpoint"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
PAIR2
CAS:PAIR2 is a selective IRE1α RNase partial antagonist, blocking its ATP site and preventing KIRA from hindering XBP1 splicing.Formula:C27H26F4N6O3SColor and Shape:SolidMolecular weight:590.59WRN inhibitor 13
CAS:WRN inhibitor 13 is an inhibitor of the WRN helicase with a pIC50 value ranging from 6 to 7.Formula:C16H20N2O5SColor and Shape:SolidMolecular weight:352.405PKMYT1-IN-7
CAS:PKMYT1-IN-7 (compound 7) is an orally active PKMYT1 inhibitor with IC50 values of 1.6 nM for PKMYT1 and 0.06 μM for pCDK1. It inhibits the phosphorylation of CDK1 at T14 and Y15 sites and exhibits anticancer activity both in vitro and in vivo.Formula:C17H18FN5O3Color and Shape:SolidMolecular weight:359.355MtTMPK-IN-1
MtTMPK-IN-1 inhibits MtTMPK with 2.5 μM IC50, shows moderate anti-tuberculosis activity, and is low in cytotoxicity.Formula:C22H24N4O3Color and Shape:SolidMolecular weight:392.45RNAP-σ interaction inhibitor-2
CAS:RNAP-σ interaction inhibitor-2 (compound 7d) is an inhibitor targeting the interaction between RNA polymerase and the sigma factor. It demonstrates inhibitory activity against S. aureus with a minimum inhibitory concentration (MIC) of 2 µg/mL.Formula:C27H19Cl3N2O6S2Color and Shape:SolidMolecular weight:637.939CLK1/4-IN-1
CLK1/4-IN-1 inhibits Clk1/4 (IC50: 9.7/6.6 nM), curbing T24 cell growth (GI50: 1.1 μM). Potential cancer research tool.Formula:C18H14ClNO4SColor and Shape:SolidMolecular weight:375.83Mazethramycin
CAS:<p>Mazethramycin is an antitumor antibiotic that exerts its effects by disrupting DNA replication and RNA synthesis within cells. It is utilized in cancer research.</p>Formula:C17H19N3O4Molecular weight:329.35Antitumor agent-74
Antitumor agent-74, a quinazoline derivative, inhibits DNA, arrests cell cycle, and induces apoptosis with agent-75.Formula:C26H23FN6Color and Shape:SolidMolecular weight:438.5CTX-712
CAS:<p>CTX-712 is a potent inhibitor of cdc2-like kinase ( CLK ). CTX-712 inhibits inhibits cancer survival and cancer cell growth.</p>Formula:C19H17FN8O2Color and Shape:SolidMolecular weight:408.39CHK1-IN-2
CAS:CHK1-IN-2 is an inhibitor of checkpoint kinase 1 (CHK1; IC50: 6 nM).Formula:C20H22N4OSPurity:98%Color and Shape:SolidMolecular weight:366.48Hesperadin hydrochloride
Hesperadin hydrochloride is an ATP-competitive indolone inhibitor of Aurora A and B, with an IC50 value of 250 nM for Aurora B.Formula:C29H33ClN4O3SColor and Shape:SolidMolecular weight:553.12Zorubicin
CAS:<p>Zorubicin, a Daunorubicin derivative, targets topoisomerase II, inhibits DNA polymerase, and researches acute leukemia, sarcomas.</p>Formula:C34H35N3O10Color and Shape:SolidMolecular weight:645.66N-Isobutyryl-2', 3'-acetyl-guanosine
CAS:N-Isobutyryl-2', 3'-acetyl-guanosine is a derivative of guanosine.Formula:C18H23N5O8Color and Shape:SolidMolecular weight:437.404CDK1-IN-4
CDK1-IN-4 inhibits CDK1 (IC50: 44.52 nM), CDK2/CDK5 less potently, impacts cell cycle, used in cancer studies.Formula:C26H24ClN5SColor and Shape:SolidMolecular weight:474.022'-O-MOE-GMP
CAS:<p>2'-O-MOE-GMP is a nucleotide analogue that can be utilized in the synthesis of oligonucleotides.</p>Formula:C13H20N5O9PColor and Shape:SolidMolecular weight:421.30FR-β ligand 1
CAS:FR-β ligand 1 (III) is a ligand that specifically targets folate receptors, exhibiting antitumor activity, high selectivity, and strong affinity.Formula:C22H25N5O6Color and Shape:SolidMolecular weight:455.46ddCTP trisodium
ddCTP trisodium, an HIV reverse transcriptase target, aids AIDS research and DNA sequencing as a ddNTP.Formula:C9H13N3Na3O12P3Color and Shape:SolidMolecular weight:517.1RAD51-IN-5
CAS:RAD51-IN-5 blocks RAD51; may aid mitochondrial disorder research. (WO2021164746A1, cmpd 3)Formula:C26H38N4O5S2Color and Shape:SolidMolecular weight:550.73CDK9-IN-13
<p>CDK9-IN-13 is a potent and selective CDK inhibitor (IC50<3 nM). CDK9-IN-13 has a very short half-life in rodents.</p>Formula:C27H35N5O2Color and Shape:SolidMolecular weight:461.6DNA polymerase-IN-6
CAS:DNA polymerase-IN-6 (Compound 27) exhibits inhibitory activity against DNA polymerase, with EC50 values of 0.33 µM for HCMV, 1.9 µM for HSV-1, 0.76 µM for HSV-2, and 0.066 µM for EBV.Formula:C26H28ClFN8O4Color and Shape:SolidMolecular weight:571.003
