Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase(111 products)
- CDK(525 products)
- Cell Cycle Arrest(4 products)
- Chk(46 products)
- DYRK(49 products)
- Dynamin(26 products)
- Ferroptosis(224 products)
- HSP(180 products)
- Integrin(256 products)
- Kinesin(86 products)
- LIM Kinase(19 products)
- Microtubule Associated(284 products)
- PKC(111 products)
- PLK(25 products)
- ROCK(66 products)
- Rho(2 products)
- Wee1(14 products)
- c-Myc(75 products)
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Found 3749 products of "Cell Cycle/Checkpoint"
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Uridine-5-(N-Fmoc-methylamino)-acetyl (9-fluorenylmethyl) ester
Uridine derivative with antitumor properties blocks DNA synthesis and induces apoptosis in lymphoid cancers.Formula:C41H37N3O10Color and Shape:SolidMolecular weight:731.75RAD51-IN-3
CAS:RAD51-IN-3 is a Rad51 inhibitor.Formula:C31H41N5O5S2Color and Shape:SolidMolecular weight:627.82Farletuzumab
CAS:Farletuzumab (MORAb-003), a humanized antibody, inhibits FRα-expressing cell growth for cancer research.Purity:> 95%Color and Shape:LiquidMolecular weight:145.36 kDaCDK9 ligand 3
CAS:<p>CDK9ligand 3 is a ligand for CDK9 and can be utilized in the synthesis of PROTAC degraders, specifically PROTAC CDK9degrader-11.</p>Formula:C18H18BrCl2N5O3Color and Shape:SolidMolecular weight:503.177CTP Synthetase-IN-1 Ammonium salt
CTP Synthetase-IN-1 Ammonium salt is a CTPS inhibitor with potential antibacterial, anti-inflammatory, and antitumor activity for the study of SARS-CoV-2 viral infectionsFormula:C20H22F3N7O3S2Purity:99.97%Color and Shape:SolidMolecular weight:529.56CDK1-IN-2
CAS:CDK1-IN-2 (cdk1 inhibitor 2) is a CDK1 inhibitor with IC50 of 5.8 μM.Formula:C17H11ClN2OPurity:98.53%Color and Shape:SoildMolecular weight:294.73KWR137
<p>KWR137 is a WRN degrader with an IC50 of 8 nM. It exhibits significant antiproliferative activity against MSI-H cells, with a GI50 of 509 nM for SW48 cells and 824 μM for HCT116. Additionally, KWR137 demonstrates antitumor growth effects in xenograft mouse models. This compound is applicable for cancer research.</p>Formula:C33H31ClF3N9O4Color and Shape:SolidMolecular weight:710.105PROTAC CDK9 degrader-8
<p>PROTAC CDK9 Degrader-8 (Compound 21) is a potent degrader of CDK9 with an IC50 of 0.01 μM, utilized in cancer research [1].</p>Formula:C44H52Cl2N10O7Purity:98%Color and Shape:SolidMolecular weight:903.85Uridine-5-oxo-acetyl-(9-fluorenylmethyl) ester
Uridine analogue with antitumor effects; inhibits DNA synthesis, induces apoptosis in lymphoid cancers.Formula:C24H24N2O9Color and Shape:SolidMolecular weight:484.46MYC-IN-2
CAS:MYC-IN-2 is a protein-protein inhibitor targeting the MYC protein, designed for use in cancer research.Formula:C25H17N3O2SColor and Shape:SolidMolecular weight:423.49(E/Z)-THZ1 2HCl
CAS:<p>THZ1 2HCl: selective CDK7 allosteric inhibitor, IC50 3.2 nM, hinders cancer cell growth.</p>Formula:C31H30Cl3N7O2Purity:99.51%Color and Shape:SolidMolecular weight:638.985-Aza-xylo-cytidine
<p>5-Aza-xylo-cytidine, a purine analog with antitumor effects, inhibits DNA synthesis and induces apoptosis in lymphoid cancers.</p>Formula:C8H12N4O5Color and Shape:SolidMolecular weight:244.2Echistatin
CAS:Potent αVβ3 integrin blocker, stops osteoclast binding & bone loss, hinders platelet aggregation. Ki=0.27 nM, IC50s: 0.1 nM (bone), 30 nM (platelets).Formula:C217H341N71O74S9Purity:98%Color and Shape:SolidMolecular weight:5417.15'-O-DMT-PAC-dA
CAS:<p>5’-O-DMT-PAC-dA can be used in the synthesis of oligoribonucleotides[1].</p>Formula:C39H37N5O7Color and Shape:SolidMolecular weight:687.74Clofarabine-5'-diphosphate
CAS:Clofarabine-5'-diphosphate (Clofarabine-DP) is a metabolite resulting from the phosphorylation of Clofarabine by deoxycytidine kinase (dCK). It can undergo further phosphorylation to become Clofarabine-5'-triphosphate, exhibiting cytotoxicity in cancer cells by inhibiting DNA synthesis and repair.Formula:C10H13ClFN5O9P2Color and Shape:SolidMolecular weight:463.64GRGDSP
CAS:<p>Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP) is used as a soluble integrin-blocking RGD-based peptide.</p>Formula:C22H37N9O10Purity:98%Color and Shape:SolidMolecular weight:587.582'-β-C-Methyl-3-deazauri dine
CAS:2’-β-C-Methyl-3-deazauridine, a purine nucleoside analogue, exhibits wide antitumor activity specifically against indolent lymphoid malignancies.Formula:C11H15NO6Color and Shape:SolidMolecular weight:257.24ChlaDUB1-IN-2
ChlaDUB1-IN-2 (Compound 27a) serves as an inhibitor of the deubiquitinating enzyme ChlaDUB1 from Chlamydia trachomatis, with an IC50 of 0.97 μM. It also inhibits the formation of Chlamydia trachomatis inclusions, exhibiting an IIC50 of 25.6 μg/mL.Formula:C22H16N6O2Color and Shape:SolidMolecular weight:396.4PROTAC CDK9 degrader 4
CAS:PROTAC CDK9 degrader 4 is a CDK9 degrader that targets transcriptional regulation and has potential anticancer activity.Formula:C43H56N10O5Color and Shape:SolidMolecular weight:792.97m7GpppCmpG
CAS:m7GpppCmpG, a trinucleotide cap analogue, enables RNA manufacturing with cap 0 or cap 1 structures.Formula:C31H43N13O25P4Color and Shape:SolidMolecular weight:1121.64
