Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase(126 products)
- CDK(578 products)
- Cell Cycle Arrest(8 products)
- Chk(50 products)
- DYRK(47 products)
- Dynamin(28 products)
- Ferroptosis(238 products)
- HSP(197 products)
- Integrin(298 products)
- Kinesin(89 products)
- LIM Kinase(23 products)
- Microtubule Associated(303 products)
- PKC(129 products)
- PLK(29 products)
- ROCK(66 products)
- Rho(7 products)
- Wee1(20 products)
- c-Myc(83 products)
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Found 2897 products for "Cell Cycle/Checkpoint".
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Adenosine Dialdehyde (ADOX)
CAS:Adenosine Dialdehyde, a purine analogue, inhibits SAHH (Ki=3.3 nM), and shows strong anti-tumor effects in vivo.Formula:C10H11N5O4Purity:95%Color and Shape:SolidMolecular weight:265.2254BSJ-5-63
CAS:BSJ-5-63 is an effective degrader of CDK12, CDK7, and CDK9. It reduces the protein expression of CDK12, CDK7, CDK9, RNAPII, and Cyclin K, and also decreases the mRNA expression of BRCA1 and BRCA2. BSJ-5-63 exhibits anticancer activity and holds potential for prostate cancer research.Formula:C52H74ClN9O6S2Color and Shape:SolidMolecular weight:1020.78TFMU-ADPr triethylamine
TFMU-ADPr triethylamine is a substrate for PARG activity measurement, releasing a fluorophore to indicate PAR hydrolase activity.Formula:C25H26F3N5O16P2·5C6H15NColor and Shape:SolidMolecular weight:1024.422-5A pentasodium
2-5A (5'-O-Triphosphoryladenylyl-(2'→5')-adenylyl-(2'→5')-adenosine) pentasodium is a 5'-triphosphorylated (2',5') oligo-adenylate. Acting as an immune mediator, 2-5A pentasodium enhances the activity of RNase L. It degrades viral mRNA and inhibits protein synthesis by binding to RNase L and activating its ribonuclease function. This compound is useful in research related to respiratory syncytial virus (RSV) and cancer.2'-Deoxy-N-methyl-AMP ammonium
2'-Deoxy-N-methyl-AMP ammonium is an N6-substituted adenine nucleotide derivative that serves as a glycoconjugate donor. It acts as a specific substrate for N6-methyl-AMP aminohydrolase, facilitating its conversion to dIMP, thus playing a role in the nucleotide metabolism cycle. Additionally, 2'-Deoxy-N-methyl-AMP ammonium functions as a donor of GDP-linked fucose derivatives, driving site-specific protein glycosylation through the action of α-1,3-fucosyltransferase. This compound is a crucial molecular tool for studying nucleotide modification and protein glycosylation mechanisms.Uridine-5-(N-Fmoc-methylamino)-acetyl (9-fluorenylmethyl) ester
Uridine derivative with antitumor properties blocks DNA synthesis and induces apoptosis in lymphoid cancers.Formula:C41H37N3O10Color and Shape:SolidMolecular weight:731.75Rachelmycin
CAS:Rachelmycin, a potent antibiotic and antitumor agent from Streptomyces zelensis, binds to DNA's minor groove.Formula:C37H33N7O8Color and Shape:SolidMolecular weight:703.712A20FMDV2
CAS:A20FMDV2 is a highly selective αvβ6 integrin inhibitor with an IC 50 of 3 nM, demonstrating 1,000-fold greater selectivity for αvβ6 compared to other RGD-directed integrins like αvβ3, αvβ5, and α5β1. This compound can be derived from the foot-and-mouth disease virus and is suitable for radiolabeling, enabling PET imaging of αvβ6 integrin-positive tumors.Formula:C93H163N31O28Color and Shape:SolidMolecular weight:2163.48RNA splicing modulator 3
CAS:RNA Splicing Modulator 3 (Compound 236) is an effective RNA splicing modulator, exhibiting an AC50 value of less than 100 nM [1].Formula:C19H20N6OSColor and Shape:SolidMolecular weight:380.47Uridine-5-oxo-acetyl-(9-fluorenylmethyl) ester
Uridine analogue with antitumor effects; inhibits DNA synthesis, induces apoptosis in lymphoid cancers.Formula:C24H24N2O9Color and Shape:SolidMolecular weight:484.46AZD8359
AZD8359 is a T-cell engager (TCE) that targets STEAP2. AZD8359 selectively recruits and activates CD8+ T cells, mediating the killing of STEAP2-positive tumor cells by T cells. AZD8359 is intended for use in oncology research.Guanosine 5'-triphosphate trisodium salt hydrate
CAS:Guanosine 5'-triphosphate trisodium salt hydrate, G-protein activator, nucleotide for synthesis, upregulates miR133, promotes myogenesis for regenerative research.Formula:C10H13N5Na3O14P3·xH2OPurity:99.22%Color and Shape:SolidMolecular weight:564.185ONX 0801 trisodium
CAS:ONX 0801 (BGC 945) trisodium is a targeted thymidylate synthase (TS) inhibitor specifically designed to act against tumors overexpressing the α-folate receptor.Formula:C32H30N5Na3O10Color and Shape:SolidMolecular weight:713.58BAY-728
BAY-728 serves as a negative control for BAY-805, a potent and selective inhibitor of USP21 [1].Formula:C24H28F3N5O2SColor and Shape:SolidMolecular weight:507.575-Chlorouridine
CAS:5-Chlorouridine, a ribonucleoside, is an inhibitor of RNase A (Ki= 44.5 μM) and eosinophil-derived neurotoxin (EDN) (Ki= 1080.1 μM; IC50= 1462.8 μM). It is utilized in research related to inflammatory diseases and hypereosinophilic syndrome.Formula:C9H11ClN2O6Molecular weight:278.646Antibacterial agent 271
Antibacterialagent 271 is an antimicrobial compound that significantly inhibits Escherichia coli, with a minimum inhibitory concentration (MIC) of 2.2 μM. It disrupts bacterial membrane integrity, reducing metabolic activity. By binding to DNA grooves, it inhibits replication and induces reactive oxygen species (ROS) accumulation, leading to bacterial death. Antibacterialagent 271 shows considerable potential in combating bacterial infections.Color and Shape:Odour Solid8-Chloro-2'-deoxy-2'-fluoro-arabino adenosine
8-Chloro-2’-deoxy-2’-fluoro-arabino adenosine, a purine nucleoside analog, demonstrates broad antitumor activity against indolent lymphoid malignancies.Formula:C10H11ClFN5O3Color and Shape:SolidMolecular weight:303.68CDK9 ligand 3
CAS:CDK9ligand 3 is a ligand for CDK9 and can be utilized in the synthesis of PROTAC degraders, specifically PROTAC CDK9degrader-11.Formula:C18H18BrCl2N5O3Color and Shape:SolidMolecular weight:503.177CDK7-IN-2 hydrochloride hydrate
CAS:CDK7-IN-2 HCl hydrate is a potent, specific CDK7 enzyme inhibitor with significant anti-cancer effects.Formula:C26H42ClN7O4Color and Shape:SolidMolecular weight:552.12N1-(2-Methyl)propyl pseudouridine
N1-(2-Methyl)propyl pseudouridine, a purine analog, targets lymphoid cancer by inhibiting DNA synthesis and inducing apoptosis.Formula:C13H20N2O6Color and Shape:SolidMolecular weight:300.31
