Cell Cycle/Checkpoint

Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.

Subcategories of "Cell Cycle/Checkpoint"

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Found 3749 products of "Cell Cycle/Checkpoint"

Purity (%)

100

products per page.

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Diguanosine 5′-triphosphate
CAS:
- 6674-45-9
Diguanosine 5′-triphosphate (Gp3G) is a kind of homodinucleotide from by GTP:GTP guanylyltransferase.
Formula:C₂₀H₂₇N₁₀O₁₈P₃
Color and Shape:Solid
Molecular weight:788.409
Ref: TM-T40776
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CDK7/9-IN-1
CAS:
- 2747919-19-1
CDK7/9-IN-1 inhibits CDK7/9 with IC50: 0.0656 μM (no pre-incubation), 0.00574 μM (3h pre-inc.), and CDK9: 2.14 μM (3h pre-inc.) for cancer research.
Formula:C₂₄H₃₂F₃N₅O₂
Color and Shape:Solid
Molecular weight:479.548
Ref: TM-T40353
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Anti-c-myc Antibody (9E10)
Anti-c-myc Antibody (9E10) is a chimeric mouse IgG1 antibody targeting human c-myc.
Color and Shape:Odour Liquid
Ref: TM-T9901A-960
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5'-O-DMT-rI
CAS:
- 119898-59-8
5’-O-DMT-Ri can be used in the synthesis of oligoribonucleotides[1].
Formula:C₃₁H₃₀N₄O₇
Color and Shape:Solid
Molecular weight:570.59
Ref: TM-T37140
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Psammaplin A
CAS:
- 110659-91-1
Psammaplin A: marine-derived, inhibits HDAC/DNA methyltransferases, strong DAC1 blocker (IC50=0.9nM), antimicrobial against Gram-positive bacteria, anticancer.
Formula:C₂₂H₂₄Br₂N₄O₆S₂
Color and Shape:Solid
Molecular weight:664.38
Ref: TM-T36303
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16,16-dimethyl Prostaglandin A1
CAS:
- 41692-24-4
16,16-dimethyl Prostaglandin A1 is a useful organic compound for research related to life sciences.
Formula:C₂₂H₃₆O₄
Color and Shape:Solid
Molecular weight:364.526
Ref: TM-T36040
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DSPE-PEG3000-iRGD
DSPE-PEG3000-iRGD is a PEG compound comprising DSPE and the αv-integrin targeting peptide (iRGD). The iRGD peptide binds to αv-integrin and undergoes proteolytic cleavage within tumors to produce CRGDK/R, interacting with neuropilin-1. This results in tumor targeting and penetration capabilities. DSPE-PEG3000-iRGD is applicable in drug delivery.
Color and Shape:Odour Solid
Ref: TM-TCL-01149
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5'-O-DMT-N4-Ac-2'-F-dC
CAS:
- 159414-98-9
5’-O-DMT-N4-Ac-2’-F-dC is a modified nucleoside and can be used to synthesize DNA or RNA.
Formula:C₃₂H₃₂FN₃O₇
Color and Shape:Solid
Molecular weight:589.61
Ref: TM-T37136
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Viquidacin
CAS:
- 904302-98-3
NXL-101, an oral/IV antibiotic for Gram-positive bacteria like MRSA, was discontinued by Novexel in 2008.
Formula:C₂₅H₂₉FN₂O₄S₂
Color and Shape:Solid
Molecular weight:504.64
Ref: TM-T35064
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Deoxythymidine-5'-triphosphate sodium hydrate
dTTP sodium hydrate, a DNA synthesis component, is a nucleoside triphosphate.
Formula:C₁₀H₁₇N₂O₁₄P₃·xNa·xH₂O
Color and Shape:Solid
Molecular weight:C10H17N2O14P3.xNa.xH2O
Ref: TM-T74122
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α-Methyl-DL-aspartic acid
CAS:
- 2792-66-7
α-Methyl-DL-aspartic acid specifically inhibits argininosuccinate synthase (ASS), the rate-limiting enzyme in 1-citrulline-to-1-arginine recycling.
Formula:C₅H₉NO₄
Purity:99.91%
Color and Shape:Solid
Molecular weight:147.13
Ref: TM-T78044
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5'-O-DMT-Bz-rC
CAS:
- 81246-76-6
5’-O-DMT-Bz-Rc is a modified nucleoside and can be used to synthesize DNA or RNA.
Formula:C₃₇H₃₅N₃O₈
Color and Shape:Solid
Molecular weight:649.69
Ref: TM-T37135
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CDK2-IN-7
CAS:
- 2498658-13-0
CDK2-IN-7 is a CDK2 inhibitor for treating cancer ( IC 50 < 50 nM).
Formula:C₂₄H₃₀N₆O₄S
Color and Shape:Solid
Molecular weight:498.6
Ref: TM-T40160
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[pThr3]-CDK5 Substrate
CAS:
- 1670273-47-8
[pThr3]-CDK5 Substrate is an effective Phospho-Thr3CDK5 Substrate.[pThr3]-CDK5 Substrate is phosphorylated by CDK5 with a Km value of 6 µM[1].
Formula:C₅₃H₁₀₀N₁₅O₁₅P
Purity:98%
Color and Shape:Solid
Molecular weight:1218.43
Ref: TM-TP1602
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2'-Deoxy-2'-fluoroadenosine 5'-monophosphate triethylammonium
2’-Deoxy-2’-fluoroadenosine 5’-monophosphate (triethylammonium) is a purine nucleoside analog with extensive antitumor properties, particularly effective
Formula:C₂₂H₄₃FN₇O₆P
Color and Shape:Solid
Molecular weight:551.59
Ref: TM-T75195
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CDK7-IN-21
CAS:
- 2766124-39-2
CDK7-IN-21 (compound A22) is a potent CDK7 inhibitor [1] .
Formula:C₃₃H₃₆FN₉O₂
Color and Shape:Solid
Molecular weight:609.7
Ref: TM-T75121
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PROTAC CDK9 degrader-11
CAS:
- 3039540-19-4
PROTAC CDK9 degrader-11 (Compound C3) is an orally active PROTAC CDK9 degrader with a DC50 of 1.09 nM. This compound exhibits cytotoxicity in small cell lung cancer (SCLC) cells, with IC50 values in the nanomolar range. It induces cell cycle arrest at the G0/G1 phase and inhibits cell invasion in DMS114 and DMS53 cells. In addition, PROTAC CDK9 degrader-11 shows antitumor activity in an NCI-H446 xenograft mouse model. (Pink: ligand for target protein CDK9 ligand 3; Black: linker; Blue: ligand for E3 ligase Cereblon E3 ligase Ligand 56)
Formula:C₃₉H₄₈Cl₂N₁₀O₅
Color and Shape:Solid
Molecular weight:807.768
Ref: TM-T205652
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TC113
TC113, a c(RGDyK)-linked Gemcitabine, targets αvβ3 integrin, entering A549 cells, and inhibits WM266.4 and A549 cell growth.
Formula:C₃₇H₅₀F₂N₁₂O₁₃
Color and Shape:Solid
Molecular weight:908.86
Ref: TM-T74400
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Chk1-IN-6
CAS:
- 2428423-77-0
Chk1-IN-6 is a potent, selective, and orally bioavailable CHK1 inhibitor candidate.
Formula:C₁₆H₁₈F₃N₇
Color and Shape:Solid
Molecular weight:365.364
Ref: TM-T40091
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WAY-230563
CAS:
- 93326-70-6
WAY-230563 is a serine/threonine kinase inhibitor that blocks CHK1/CHK2-mediated cell cycle checkpoints, leading to G2/M phase arrest in tumour cells
Formula:C₁₇H₁₂N₂O₂S
Purity:98.40%
Color and Shape:Solid
Molecular weight:308.35
Ref: TM-T202246