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Cell Cycle/Checkpoint

Cell Cycle/Checkpoint

Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.

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Found 3756 products of "Cell Cycle/Checkpoint"

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  • Rev 2'-O-MOE-5MeC(Bz)-5'-amidite


    Rev 2’-O-MOE-5MeC(Bz)-5’-amidite, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies.
    Formula:C50H60N5O10P
    Color and Shape:Solid
    Molecular weight:922.01
  • Eesperamicin A1

    CAS:
    Esperamicin A1, a powerful antitumor drug, comes from Actinomadura verrucosospora.
    Formula:C59H80N4O22S4
    Color and Shape:Solid
    Molecular weight:1325.54
  • Tirandamycin A


    Tirandamycin A is a useful organic compound for research related to life sciences and the catalog number is T124996.
    Formula:C22H27NO7
    Color and Shape:Solid
    Molecular weight:417.458
  • 6-Amino-4-hydrozino-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine


    6-Amino-4-hydrozino-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine, a pyrimidine nucleoside analog, boasts a broad spectrum of biochemical and
    Formula:C10H17N7O3
    Color and Shape:Solid
    Molecular weight:283.29
  • RNA splicing modulator 2

    CAS:
    RNA splicing modulator 2 (compound 256) is a RNA splicing modulator [1] .
    Formula:C20H21N5OS
    Color and Shape:Solid
    Molecular weight:379.48
  • STX-100


    PY314 is a CHO-expressed humanized monoclonal antibody targeting TREM2 with antitumor activity for the study of metastatic renal cell carcinoma.
    Purity:97.3% (SDS-PAGE); 97.5% (SEC-HPLC) - 97.3% (SDS-PAGE); 97.5% (SEC-HPLC)
    Color and Shape:Odour Liquid
  • UnyLinker 12 TEA


    UnyLinker 12 TEA is a versatile linker used in the synthesis of oligoribonucleotides.
    Formula:C39H35NO10C6H15N
    Color and Shape:Solid
    Molecular weight:778.34655
  • LXY3

    CAS:
    LXY3 (LXY2) is a VLA-3 blocking peptide that inhibits the interaction of neutrophil surface integrin α3β1 (VLA-3) with laminin in the basement membrane, thereby preventing neutrophil migration across the tumor vascular basement membrane barrier. LXY3 is employed to block the neutrophil-mediated release of nanoparticles from the perivascular pool into the tumor stroma and is frequently used for targeted imaging in breast cancer.
    Formula:C32H43N11O15S2
    Color and Shape:Solid
    Molecular weight:885.88
  • PD-1/PD-L1-IN-50


    Compound LG-12, known chemically as PD-1/PD-L1-IN-50, is an inhibitor of PD-1/PD-L1. It enhances the secretion of IFN-γ, promotes the activation of CD8+ T cells, and activates T cell-mediated anti-tumor immunity.
    Color and Shape:Odour Solid
  • 3,5'-Bis(O-t-butyldimethylsilyl)-2'-O-methyl-5-methyl cytidine


    3,5’-Bis(O-t-butyldimethylsilyl)-2’-O-methyl-5-methyl cytidine, a cytidine analog, inhibits DNA methyltransferases (e.g., Zebularine), exhibiting potential anti
    Formula:C23H45N3O5Si2
    Color and Shape:Solid
    Molecular weight:499.79
  • Heliquinomycin

    CAS:
    Heliquinomycin, a Streptomyces metabolite, inhibits DNA helicase (Ki=6.8 μM) and fights Gram-positive bacteria and various cancer cells.
    Formula:C33H30O17
    Color and Shape:Solid
    Molecular weight:698.586
  • CDK7-IN-6

    CAS:
    CDK7-IN-6, a potent CDK7 inhibitor (IC50 ≤100 nM), from WO2019197549 A1, is >200x selective over CDK1/2/5, promising for cancer research.
    Formula:C26H34ClN9O
    Color and Shape:Solid
    Molecular weight:524.07
  • N4-Benzoyl-2'-deoxy-2'-fluoro-β-D-arabinocytidine


    N4-Benzoyl-2’-deoxy-2’-fluoro-β-D-arabinocytidine, a purine nucleoside analog, exhibits widespread antitumor activity, particularly against indolent lymphoid
    Formula:C16H16FN3O5
    Color and Shape:Solid
    Molecular weight:349.31
  • N1-Methyl-2'-O-(2-methoxyethyl) adenosine


    N1-Methyl-2’-O-(2-methoxyethyl) adenosine, a purine nucleoside analog, exhibits broad antitumor effects, particularly against indolent lymphoid malignancies.
    Formula:C14H21N5O5
    Color and Shape:Solid
    Molecular weight:339.35
  • (1S,3R,5R)-PIM447 dihydrochloride


    (1S,3R,5R)-PIM447 (dihydrochloride) an inhibitor of PIM(IC50 of 0.095 μM for Pim1, 0.522 μM for Pim2 and 0.369 μM for Pim3).
    Formula:C24H25Cl2F3N4O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:513.38
  • 5'-ODMT cEt G Phosphoramidite (Amidite)

    CAS:
    5'-ODMT cEt G Amidite is a safe, effective nucleic acid analog with strong antisense activity.
    Formula:C46H56N7O9P
    Color and Shape:Solid
    Molecular weight:881.95
  • 2'-Fluoro-2'-deoxy-arabinoadenosine 5'-triphosphate triethylamine


    2’-Fluoro-2’-deoxy-arabinoadenosine 5’-triphosphate (triethylamine) is a purine nucleoside analog with significant antitumor properties, particularly effective
    Formula:C34H75FN9O12P3
    Color and Shape:Solid
    Molecular weight:913.93
  • L-Inosine

    CAS:
    L-Inosine, an endogenous purine nucleoside from adenosine metabolism, has anti-inflammatory, antinociceptive, immunomodulatory, and neuroprotective properties.
    Formula:C10H12N4O5
    Color and Shape:Solid
    Molecular weight:268.23
  • Chrysomycin A

    CAS:
    Chrysomycin A is an antibiotic that can be derived from Streptomyces.
    Formula:C28H28O9
    Color and Shape:Solid
    Molecular weight:508.52
  • Anti-MRSA agent 7


    Compound 12: a potent anti-MRSA, inhibits S. aureus/E. coli DNA gyrases/topo IV; IC50: 0.185-0.365/0.341-0.059 μM.
    Formula:C22H20BrF2N3O4
    Color and Shape:Solid
    Molecular weight:508.31