PKC
PKC (Protein Kinase C) inhibitors target the PKC family of serine/threonine kinases, which are involved in a wide range of cellular processes, including cell cycle regulation, apoptosis, and differentiation. PKC plays a key role in signal transduction pathways that influence cell proliferation and survival. Inhibiting PKC can lead to changes in cell cycle progression, making these inhibitors valuable in research related to cancer, neurobiology, and cardiovascular diseases. At CymitQuimica, we provide a diverse selection of high-quality PKC inhibitors to support your research in signal transduction, cell cycle regulation, and therapeutic development.
Found 102 products of "PKC"
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Taurochenodeoxycholic Acid
CAS:<p>Taurochenodeoxycholic Acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid.</p>Formula:C26H45NO6SPurity:99.53% - 99.86%Color and Shape:SolidMolecular weight:499.7Valrubicin
CAS:<p>Valrubicin (AD-32) (AD 32) inhibits TPA- and PDBu-induced PKC activation (IC50s: 0.85 and 1.25 μM) and has antitumor and anti-inflammatory activity.</p>Formula:C34H36F3NO13Purity:98.63%Color and Shape:SolidMolecular weight:723.64Go 6983
CAS:<p>Go 6983 is a PKC inhibitor with IC50 values of 7, 7, 6, 10, and 60 nM for PKCα, PKCβ, PKCγ, PKCδ, and PKCζ, respectively. High-Quality, Low-Cost!</p>Formula:C26H26N4O3Purity:98.41% - 99.85%Color and Shape:SolidMolecular weight:442.51Darovasertib
CAS:<p>Darovasertib (LXS196) is a potent PKC inhibitor, orally active, with IC50 of 1.9 nM (PKCα), 0.4 nM (PKCθ), 3.1 μM (GSK3β).</p>Formula:C22H23F3N8OPurity:98.72% - ≥95%Color and Shape:SolidMolecular weight:472.47Taurochenodeoxycholic acid sodium
CAS:<p>Sodium taurochenodeoxycholate: induces apoptosis, anti-inflammatory, boosts insulin, stimulates α2-cells, increases [Ca(2+)](c).</p>Formula:C26H44NNaO6SPurity:98.23% - 99.45%Color and Shape:White To Off-White PowderMolecular weight:521.68Fasudil hydrochloride
CAS:<p>Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.</p>Formula:C14H18ClN3O2SPurity:99.54% - ≥95%Color and Shape:White SolidMolecular weight:327.83Verbascoside
CAS:<p>Verbascoside (Kusaginin) is a protein kinase C inhibitor with antimicrobial, anti-inflammatory activities.</p>Formula:C29H36O15Purity:97.46% - 99.55%Color and Shape:SolidMolecular weight:624.59Phorbol 12-myristate 13-acetate
CAS:<p>Phorbol 12-myristate 13-acetate (PMA) belongs to the phorbol ester group of natural products and is an activator of PKC, SphK, and NF-κB.</p>Formula:C36H56O8Purity:98.55% - >99.99%Color and Shape:White To Off-White SolidMolecular weight:616.83Afuresertib hydrochloride
CAS:<p>Afuresertib hydrochloride is an inhibitor of Akt kinase (Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 respectively)</p>Formula:C18H18Cl3FN4OSPurity:99.96%Color and Shape:SolidMolecular weight:463.8TAS-301
CAS:<p>TAS-301, an inhibitor of smooth muscle cell migration and proliferation, inhibits intimal thickening after balloon injury to rat carotid arteries.</p>Formula:C23H19NO3Purity:99.55%Color and Shape:SolidMolecular weight:357.4Midostaurin
CAS:<p>PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor.</p>Formula:C35H30N4O4Purity:97.61% - >99.99%Color and Shape:SolidMolecular weight:570.64Daphnetin
CAS:<p>Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),</p>Formula:C9H6O4Purity:97.47% - 99.8%Color and Shape:SolidMolecular weight:178.14Chelerythrine
CAS:<p>1.</p>Formula:C21H18NO4Purity:98.36%Color and Shape:SolidMolecular weight:348.37Sotrastaurin
CAS:<p>Sotrastaurin (AEB071) is a potent pan-PKC inhibitor (Kis: 0.95/0.64/2.1/3.2/1.8/0.22 nM for PKCα/βI/δ/ε/η/θ).</p>Formula:C25H22N6O2Purity:98% - 99.70%Color and Shape:SolidMolecular weight:438.48Decursin
CAS:<p>Decursin: potential antiepileptic, hepatoprotective, anti-cancer, anti-amnesic; affects NOX activation, PKCα/MAPK/NF-κB pathways, AChE.</p>Formula:C19H20O5Purity:97.22% - 99.84%Color and Shape:SolidMolecular weight:328.36Ζ-Stat
CAS:<p>ζ-Stat (NSC37044), a specific and atypical inhibitor of PKC-ζ with an IC50 of 5 μM, demonstrates the ability to inhibit proliferation and induce apoptosis in</p>Formula:C10H8O10S3Purity:99.85%Color and Shape:SolidMolecular weight:384.36Chelerythrine chloride
CAS:<p>Chelerythrine Chloride is a cell-permeable inhibitor of protein kinase C, competitive with respect to the phosphate acceptor and non-competitive with respect to</p>Formula:C21H18ClNO4Purity:95% - 99.19%Color and Shape:Yellow To Orange SolidMolecular weight:383.83R59949
CAS:<p>R59949 is used as a Diacylglycerol kinase (DGK) inhibitor.</p>Formula:C28H25F2N3OSPurity:97.04%Color and Shape:SolidMolecular weight:489.58Taurolithocholic acid sodium salt
CAS:<p>Taurolithocholic acid sodium salt (Sodium taurolithocholate) is the major human metabolite, a bile acid which inhibits radioligand binding to muscarinic M1, but</p>Formula:C26H44NNaO5SPurity:99.79% - 99.93%Color and Shape:SolidMolecular weight:505.69Desmethylglycitein
CAS:<p>Desmethylglycitein (6,7,4'-Trihydroxyisoflavone) , is a novel inhibitor of PKCα in suppressing solar UV-induced matrix metalloproteinase 1, which has</p>Formula:C15H10O5Purity:97.93%Color and Shape:SolidMolecular weight:270.24
