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PKC

PKC

PKC (Protein Kinase C) inhibitors target the PKC family of serine/threonine kinases, which are involved in a wide range of cellular processes, including cell cycle regulation, apoptosis, and differentiation. PKC plays a key role in signal transduction pathways that influence cell proliferation and survival. Inhibiting PKC can lead to changes in cell cycle progression, making these inhibitors valuable in research related to cancer, neurobiology, and cardiovascular diseases. At CymitQuimica, we provide a diverse selection of high-quality PKC inhibitors to support your research in signal transduction, cell cycle regulation, and therapeutic development.

Found 129 products for "PKC".

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  • [Ala9,10, Lys11,12] Glycogen Synthase (1-12)
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    [Ala9,10, Lys11,12] Glycogen Synthase (1-12)

    CAS:
    [Ala9,10, Lys11,12] Glycogen Synthase (1-12): PKC's selective phosphorylation substrate, used to assess PKC activity. [1]
    Formula:C56H103N17O16
    Color and Shape:Solid
    Molecular weight:1270.52

    Ref: TM-T76380

  • Protein Kinase C Peptide Substrate
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    Protein Kinase C Peptide Substrate

    CAS:
    PKC Peptide Substrate acts on cell spacers, driven by second messengers/adaptors due to external signals via g protein/tyrosine kinase receptors.
    Formula:C83H155N39O21S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:2067.43

    Ref: TM-TP1051

  • Bisindolylmaleimide III hydrochloride
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    Bisindolylmaleimide III hydrochloride

    CAS:
    Bisindolylmaleimide III hydrochloride is a potent selective PKC inhibitor; ATP-competitive; blocks phosphorylation cascades; immune and cancer research.
    Formula:C23H21ClN4O2
    Purity:99.62%
    Molecular weight:420.89

    Ref: TM-T212746

  • [Ala113]MBP(104-118)
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    [Ala113]MBP(104-118)

    CAS:
    Synthetic peptide analog of bovine myelin basic protein (MBP). Non-competitive inhibitor of PKC (IC50 = 28 - 62 mM).
    Formula:C67H104N20O19
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1493.68

    Ref: TM-TP1888

  • TAT-SAMβA
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    TAT-SAMβA

    TAT-SAMβA, an RNAENFDRF (SAMβA) peptide conjugated to the TAT 47–57 protein-derived cell-penetrating peptide, acts as a selective antagonist of the Mfn1-βIIPKC
    Formula:C118H195N51O31
    Purity:98%
    Color and Shape:Solid
    Molecular weight:2824.13

    Ref: TM-T80514

  • [Ala107]MBP(104-118)
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    [Ala107]MBP(104-118)

    CAS:
    Synthetic peptide analog of bovine myelin basic protein (MBP). Non-competitive inhibitor of PKC (IC50 = 46 - 145 mM).
    Formula:C67H104N20O19
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1493.68

    Ref: TM-TP1887

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    (8R)-8-Hydroxyepoxyboetirane A

    (8R)-8-Hydroxyepoxyboetirane A is a neuroactivating compound that interacts with PKCδ-C1B. This compound binds into the PKC enzyme pocket through hydrogen bonds with glycine-253, leucine-251, and threonine-242. It induces the release of NRG1 and promotes the differentiation of neural stem cells into neurons. (8R)-8-Hydroxyepoxyboetirane A holds potential for research into nervous system disorders.
    Color and Shape:Odour Solid

    Ref: TM-T200548

  • Pep2m, myristoylated
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    Pep2m, myristoylated

    CAS:
    Myristoylated pep2m peptide; inhibits GluA2-NSF interaction, reducing AMPA receptor function and surface expression.
    Formula:C63H118N18O14S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1383.8

    Ref: TM-TP1945

  • ε-V1-2
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    ε-V1-2

    CAS:
    Protein kinase C (PKC ) is a calcium-independent, phospholipid- and diacylglycerol-dependent serine/threonine kinase involved in diverse signaling pathways,
    Formula:C37H65N9O13
    Purity:97.09%
    Molecular weight:843.9645

    Ref: TM-T35827

  • Protein Kinase C (19-35) Peptide
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    Protein Kinase C (19-35) Peptide

    CAS:
    PKC (19-35) Peptide inhibits PKC by blocking its substrate-binding, rendering cytoplasmic PKC inactive.
    Formula:C89H153N33O22
    Color and Shape:Solid
    Molecular weight:2037.4

    Ref: TM-T76456

  • Bisindolylmaleimide XI hydrochloride
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    Bisindolylmaleimide XI hydrochloride

    CAS:
    Bisindolylmaleimide XI hydrochloride (Ro 32-0432) is an orally active pan-PKC inhibitor that inhibits PKCα, PKCβI, PKCβII, and PKCγ.
    Formula:C28H29ClN4O2
    Purity:99.45%
    Color and Shape:Red Solid
    Molecular weight:489.01

    Ref: TM-T36228

  • Sangivamycin
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    Sangivamycin

    CAS:
    Sangivamycin (NSC-65346) inhibits PKC (Ki=10μM) and hinders growth in various human cancers.
    Formula:C12H15N5O5
    Purity:99.85%
    Color and Shape:Solid
    Molecular weight:309.278

    Ref: TM-T9605

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    PKCε inhibitor peptide,myristoylated

    Myristoylated PKCε inhibitor peptide (Myr-PKCε-) is a cell-permeable inhibitor consisting of a peptide linked to myristic acid that specifically inhibits
    Formula:C51H91N9O14
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1054.32

    Ref: TM-T80511

  • PKCδ Peptide Substrate
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    PKCδ Peptide Substrate

    CAS:
    PKCδ Peptide Substrate is a highly specific substrate for the δ-type of Protein kinase C, composed of a sequence that mirrors murine eEF-1α (422-443) and
    Formula:C109H191N35O29S
    Color and Shape:Solid
    Molecular weight:2487.97

    Ref: TM-T76412

  • Protein kinase C α peptide TFA
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    Protein kinase C α peptide TFA

    CAS:
    Protein Kinase C (alpha) Peptide (TFA) is a PKC-α-associated peptide functioning as a lipid-dependent serine/threonine protein kinase.
    Formula:C68H115F3N24O26S
    Color and Shape:Solid
    Molecular weight:1773.85

    Ref: TM-T76388

  • NPC-15437 dihydrochloride
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    NPC-15437 dihydrochloride

    CAS:
    NPC-15437 dihydrochloride is a PKC inhibitor blocking enzyme activity and phorbol ester binding, selective over other kinases, in cellular signaling research.
    Formula:C25H52Cl2N4O2
    Purity:98%
    Color and Shape:White Solid
    Molecular weight:511.62

    Ref: TM-T37480

  • Bisindolylmaleimide III
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    Bisindolylmaleimide III

    CAS:
    Bisindolylmaleimide III is a potent and selective inhibitor of protein kinase C (PKC).Bisindolylmaleimide III selectively interacts with PKCα or ribosomal S6
    Formula:C23H20N4O2
    Purity:97.2%
    Color and Shape:Solid
    Molecular weight:384.4305

    Ref: TM-T77628

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    SAMβA TFA

    SAMβA TFA, a selective antagonist of Mfn1-βIIPKC association conjugated to the cell permeable peptide TAT47-57, is a rationally designed inhibitor that improves
    Formula:C50H73N17O16·xC2HF3O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1168.22 (free acid)

    Ref: TM-T78220

  • PKC-θ inhibitor
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    PKC-θ inhibitor

    CAS:
    PKC-theta inhibitor is PKC-θinhibitor, with an IC50 of 12 nM.
    Formula:C20H25F3N6O3
    Purity:99.46%
    Color and Shape:Solid
    Molecular weight:454.4461

    Ref: TM-T5423

  • (±)-1,2-Diolein
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    (±)-1,2-Diolein

    CAS:
    (±)-1,2-Diolein (1,2-Dioleoyl-rac-glycerol) (1,2-Dioleoyl-rac-glycerol) is a PKC activator. (±)-1,2-Diolein could increases myotubes Ca 2+ influx.
    Formula:C39H72O5
    Color and Shape:Solid
    Molecular weight:620.99

    Ref: TM-T40101