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PKC

PKC

PKC (Protein Kinase C) inhibitors target the PKC family of serine/threonine kinases, which are involved in a wide range of cellular processes, including cell cycle regulation, apoptosis, and differentiation. PKC plays a key role in signal transduction pathways that influence cell proliferation and survival. Inhibiting PKC can lead to changes in cell cycle progression, making these inhibitors valuable in research related to cancer, neurobiology, and cardiovascular diseases. At CymitQuimica, we provide a diverse selection of high-quality PKC inhibitors to support your research in signal transduction, cell cycle regulation, and therapeutic development.

Found 129 products for "PKC".

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  • PKC-θ inhibitor
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    PKC-θ inhibitor

    CAS:
    PKC-theta inhibitor is PKC-θinhibitor, with an IC50 of 12 nM.
    Formula:C20H25F3N6O3
    Purity:99.46%
    Color and Shape:Solid
    Molecular weight:454.4461

    Ref: TM-T5423

  • Daphnoretin
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    Daphnoretin

    CAS:
    1.
    Formula:C19H12O7
    Purity:98% - 99.85%
    Color and Shape:Solid
    Molecular weight:352.2944

    Ref: TM-T4S1335

  • PKC-iota inhibitor 1
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    PKC-iota inhibitor 1

    CAS:
    PKC-iota inhibitor 1 is an inhibitor of protein kinase C-iota (PKC-ι ; IC50 : 0.34 μM)
    Formula:C21H22N6O
    Purity:98.82%
    Color and Shape:Solid
    Molecular weight:374.439

    Ref: TM-T8764

  • Taurochenodeoxycholic Acid
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    Taurochenodeoxycholic Acid

    CAS:
    Taurochenodeoxycholic Acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid.
    Formula:C26H45NO6S
    Purity:99.48% - 99.86%
    Color and Shape:Solid
    Molecular weight:499.7

    Ref: TM-T2A2481

  • Valrubicin
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    Valrubicin

    CAS:
    Valrubicin (AD-32) (AD 32) inhibits TPA- and PDBu-induced PKC activation (IC50s: 0.85 and 1.25 μM) and has antitumor and anti-inflammatory activity.
    Formula:C34H36F3NO13
    Purity:98.63%
    Color and Shape:Solid
    Molecular weight:723.6437

    Ref: TM-T7604

  • Go 6983
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    Go 6983

    CAS:
    Go 6983 is a PKC inhibitor with IC50 values of 7, 7, 6, 10, and 60 nM for PKCα, PKCβ, PKCγ, PKCδ, and PKCζ, respectively. High-Quality, Low-Cost!
    Formula:C26H26N4O3
    Purity:98.41% - 99.85%
    Color and Shape:Solid
    Molecular weight:442.51

    Ref: TM-T6313

  • Darovasertib
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    Darovasertib

    CAS:
    Darovasertib (LXS196) is a potent PKC inhibitor, orally active, with IC50 of 1.9 nM (PKCα), 0.4 nM (PKCθ), 3.1 μM (GSK3β).
    Formula:C22H23F3N8O
    Purity:99.1% - ≥95%
    Color and Shape:Solid
    Molecular weight:472.4662

    Ref: TM-T5600

  • Taurochenodeoxycholic acid sodium
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    Taurochenodeoxycholic acid sodium

    CAS:
    Sodium taurochenodeoxycholate: induces apoptosis, anti-inflammatory, boosts insulin, stimulates α2-cells, increases [Ca(2+)](c).
    Formula:C26H44NNaO6S
    Purity:98.23% - 99.56%
    Color and Shape:White Solid
    Molecular weight:521.685

    Ref: TM-TN2215

  • Fasudil hydrochloride
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    Fasudil hydrochloride

    CAS:
    Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.
    Formula:C14H18ClN3O2S
    Purity:99.54% - ≥95%
    Color and Shape:White Solid
    Molecular weight:327.83

    Ref: TM-T3060

  • Verbascoside
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    Verbascoside

    CAS:
    Verbascoside (Kusaginin) is a protein kinase C inhibitor with antimicrobial, anti-inflammatory activities.
    Formula:C29H36O15
    Purity:97.46% - 99.98%
    Color and Shape:Yellow Solid
    Molecular weight:624.5871

    Ref: TM-T3375

  • [Ala113]-MBP (104-118) acetate
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    [Ala113]-MBP (104-118) acetate

    [Ala113]MBP(104-118) acetate is an noncompetitive peptide inhibitors of protein kinase C (PKC), with IC50s ranging from 28-62 μM.
    Formula:C69H108N20O21
    Purity:95.50%
    Color and Shape:Solid
    Molecular weight:1553.74

    Ref: TM-TP1888L1

  • Phorbol 12-myristate 13-acetate
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    Phorbol 12-myristate 13-acetate

    CAS:
    Phorbol 12-myristate 13-acetate (PMA) belongs to the phorbol ester group of natural products and is an activator of PKC, SphK, and NF-κB.
    Formula:C36H56O8
    Purity:98.55% - >99.99%
    Color and Shape:White Solid
    Molecular weight:616.83

    Ref: TM-TQ0198

  • Afuresertib hydrochloride
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    Afuresertib hydrochloride

    CAS:
    Afuresertib hydrochloride is an inhibitor of Akt kinase (Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 respectively)
    Formula:C18H18Cl3FN4OS
    Purity:99.96%
    Color and Shape:Solid
    Molecular weight:463.784

    Ref: TM-T7885

  • TAS-301
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    TAS-301

    CAS:
    TAS-301, an inhibitor of smooth muscle cell migration and proliferation, inhibits intimal thickening after balloon injury to rat carotid arteries.
    Formula:C23H19NO3
    Purity:99.98%
    Color and Shape:Solid
    Molecular weight:357.4

    Ref: TM-T2441

  • Midostaurin
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    Midostaurin

    CAS:
    PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor.
    Formula:C35H30N4O4
    Purity:97.61% - >99.99%
    Color and Shape:Solid
    Molecular weight:570.64

    Ref: TM-T3211

  • Daphnetin
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    Daphnetin

    CAS:
    Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),
    Formula:C9H6O4
    Purity:97.47% - 99.95%
    Color and Shape:Solid
    Molecular weight:178.1415

    Ref: TM-T2851

  • Chelerythrine
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    Chelerythrine

    CAS:
    1.
    Formula:C21H18NO4
    Purity:98.36% - 99.96%
    Color and Shape:Yellow Solid
    Molecular weight:348.37

    Ref: TM-T6S0052

  • Sotrastaurin
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    Sotrastaurin

    CAS:
    Sotrastaurin (AEB071) is a potent pan-PKC inhibitor (Kis: 0.95/0.64/2.1/3.2/1.8/0.22 nM for PKCα/βI/δ/ε/η/θ).
    Formula:C25H22N6O2
    Purity:98% - 99.70%
    Color and Shape:Orange Solid
    Molecular weight:438.4812

    Ref: TM-T6278

  • Decursin
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    Decursin

    CAS:
    Decursin: potential antiepileptic, hepatoprotective, anti-cancer, anti-amnesic; affects NOX activation, PKCα/MAPK/NF-κB pathways, AChE.
    Formula:C19H20O5
    Purity:97.22% - 99.91%
    Color and Shape:White Solid
    Molecular weight:328.3591

    Ref: TM-T3S1416

  • Ζ-Stat
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    Ζ-Stat

    CAS:
    ζ-Stat (NSC37044), a specific and atypical inhibitor of PKC-ζ with an IC50 of 5 μM, demonstrates the ability to inhibit proliferation and induce apoptosis in
    Formula:C10H8O10S3
    Purity:99.85%
    Color and Shape:Solid
    Molecular weight:384.36

    Ref: TM-T35407