PKC
PKC (Protein Kinase C) inhibitors target the PKC family of serine/threonine kinases, which are involved in a wide range of cellular processes, including cell cycle regulation, apoptosis, and differentiation. PKC plays a key role in signal transduction pathways that influence cell proliferation and survival. Inhibiting PKC can lead to changes in cell cycle progression, making these inhibitors valuable in research related to cancer, neurobiology, and cardiovascular diseases. At CymitQuimica, we provide a diverse selection of high-quality PKC inhibitors to support your research in signal transduction, cell cycle regulation, and therapeutic development.
Found 130 products for "PKC".
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(±)-1,2-Diolein
CAS:(±)-1,2-Diolein (1,2-Dioleoyl-rac-glycerol) (1,2-Dioleoyl-rac-glycerol) is a PKC activator. (±)-1,2-Diolein could increases myotubes Ca 2+ influx.Formula:C39H72O5Color and Shape:SolidMolecular weight:620.99Ro 31-8220 Mesylate
CAS:Ro 31-8220 Mesylate (Bisindolylmaleimide IX mesylate) is a pan-PKC inhibitor, and also shows potent inhibition against MSK1, MAPKAP-K1b, S6K1, and GSK3β.Formula:C25H23N5O2S·CH4O3SPurity:98.79% - 99.02%Color and Shape:Orange SolidMolecular weight:553.65Ref: TM-T6643
1mg49.00€2mg64.00€5mg92.00€1mL*10mM (DMSO)118.00€10mg150.00€25mg230.00€50mg319.00€100mg475.00€PKC-iota inhibitor 1
CAS:PKC-iota inhibitor 1 is an inhibitor of protein kinase C-iota (PKC-ι ; IC50 : 0.34 μM)Formula:C21H22N6OPurity:98.82%Color and Shape:SolidMolecular weight:374.44Ref: TM-T8764
1mg107.00€2mg152.00€5mg219.00€1mL*10mM (DMSO)226.00€10mg349.00€25mg583.00€50mg833.00€100mg1,134.00€500mg2,268.00€Taurochenodeoxycholic Acid
CAS:Taurochenodeoxycholic Acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid.Formula:C26H45NO6SPurity:99.48% - 99.86%Color and Shape:SolidMolecular weight:499.7Valrubicin
CAS:Valrubicin (AD-32) (AD 32) inhibits TPA- and PDBu-induced PKC activation (IC50s: 0.85 and 1.25 μM) and has antitumor and anti-inflammatory activity.Formula:C34H36F3NO13Purity:98.63%Color and Shape:SolidMolecular weight:723.64Go 6983
CAS:Go 6983 is a PKC inhibitor with IC50 values of 7, 7, 6, 10, and 60 nM for PKCα, PKCβ, PKCγ, PKCδ, and PKCζ, respectively. High-Quality, Low-Cost!Formula:C26H26N4O3Purity:98.41% - 99.85%Color and Shape:SolidMolecular weight:442.51Ref: TM-T6313
1mg40.00€2mg52.00€5mg79.00€1mL*10mM (DMSO)84.00€10mg119.00€25mg233.00€50mg368.00€100mg533.00€Darovasertib
CAS:Darovasertib (LXS196) is a potent PKC inhibitor, orally active, with IC50 of 1.9 nM (PKCα), 0.4 nM (PKCθ), 3.1 μM (GSK3β).Formula:C22H23F3N8OPurity:99.1% - ≥95%Color and Shape:SolidMolecular weight:472.47Taurochenodeoxycholic acid sodium
CAS:Sodium taurochenodeoxycholate: induces apoptosis, anti-inflammatory, boosts insulin, stimulates α2-cells, increases [Ca(2+)](c).Formula:C26H44NNaO6SPurity:98.23% - 99.56%Color and Shape:White SolidMolecular weight:521.68Fasudil hydrochloride
CAS:Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.Formula:C14H18ClN3O2SPurity:99.54% - ≥95%Color and Shape:White SolidMolecular weight:327.83Verbascoside
CAS:Verbascoside (Kusaginin) is a protein kinase C inhibitor with antimicrobial, anti-inflammatory activities.Formula:C29H36O15Purity:97.46% - 99.98%Color and Shape:Yellow SolidMolecular weight:624.59Ref: TM-T3375
2mg39.00€5mg58.00€1mL*10mM (DMSO)81.00€10mg88.00€25mg168.00€50mg255.00€100mg359.00€200mg525.00€[Ala113]-MBP (104-118) acetate
[Ala113]MBP(104-118) acetate is an noncompetitive peptide inhibitors of protein kinase C (PKC), with IC50s ranging from 28-62 μM.Formula:C69H108N20O21Purity:95.50%Color and Shape:SolidMolecular weight:1553.74Phorbol 12-myristate 13-acetate
CAS:Phorbol 12-myristate 13-acetate (PMA) belongs to the phorbol ester group of natural products and is an activator of PKC, SphK, and NF-κB.Formula:C36H56O8Purity:98.55% - >99.99%Color and Shape:White SolidMolecular weight:616.83Afuresertib hydrochloride
CAS:Afuresertib hydrochloride is an inhibitor of Akt kinase (Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 respectively)Formula:C18H18Cl3FN4OSPurity:99.96%Color and Shape:SolidMolecular weight:463.8Ref: TM-T7885
2mg49.00€5mg71.00€1mL*10mM (DMSO)71.00€10mg89.00€25mg155.00€50mg240.00€100mg414.00€200mg538.00€TAS-301
CAS:TAS-301, an inhibitor of smooth muscle cell migration and proliferation, inhibits intimal thickening after balloon injury to rat carotid arteries.Formula:C23H19NO3Purity:99.98%Color and Shape:SolidMolecular weight:357.4Midostaurin
CAS:PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor.Formula:C35H30N4O4Purity:97.61% - >99.99%Color and Shape:SolidMolecular weight:570.64Ref: TM-T3211
1mg49.00€5mg84.00€1mL*10mM (DMSO)90.00€10mg119.00€25mg205.00€50mg310.00€100mg462.00€500mg1,035.00€Daphnetin
CAS:Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),Formula:C9H6O4Purity:97.47% - 99.95%Color and Shape:SolidMolecular weight:178.142Chelerythrine
CAS:1.Formula:C21H18NO4Purity:98.36% - 99.96%Color and Shape:Yellow SolidMolecular weight:348.37Sotrastaurin
CAS:Sotrastaurin (AEB071) is a potent pan-PKC inhibitor (Kis: 0.95/0.64/2.1/3.2/1.8/0.22 nM for PKCα/βI/δ/ε/η/θ).Formula:C25H22N6O2Purity:98% - 99.70%Color and Shape:Orange SolidMolecular weight:438.48Ref: TM-T6278
1mg44.00€5mg86.00€1mL*10mM (DMSO)94.00€10mg135.00€25mg254.00€50mg423.00€100mg605.00€200mg845.00€Decursin
CAS:Decursin: potential antiepileptic, hepatoprotective, anti-cancer, anti-amnesic; affects NOX activation, PKCα/MAPK/NF-κB pathways, AChE.Formula:C19H20O5Purity:97.22% - 99.91%Color and Shape:White SolidMolecular weight:328.36Ref: TM-T3S1416
1mg40.00€5mg84.00€1mL*10mM (DMSO)93.00€10mg113.00€25mg245.00€50mg439.00€100mg627.00€500mg1,288.00€Ζ-Stat
CAS:ζ-Stat (NSC37044), a specific and atypical inhibitor of PKC-ζ with an IC50 of 5 μM, demonstrates the ability to inhibit proliferation and induce apoptosis inFormula:C10H8O10S3Purity:99.85%Color and Shape:SolidMolecular weight:384.36
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