Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2235 products of "Chromatin/Epigenetics"
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PJ34 hydrochloride
CAS:<p>PJ34 hydrochloride (PJ34 HCl) is a potent specific inhibitor of PARPl/2.</p>Formula:C17H18ClN3O2Purity:98.87% - ≥95%Color and Shape:SolidMolecular weight:331.8G007-LK
CAS:<p>G007-LK is a selective inhibitor of TNKS1 and TNKS2, with IC50s of 46 nM and 25 nM, respectively.</p>Formula:C25H16ClN7O3SPurity:97.63% - 98.17%Color and Shape:SolidMolecular weight:529.96JQKD82
CAS:<p>JQKD82 is a selective inhibitor of KDM5 and increases H3K4me3. JQKD82 can be used in studies about the treatment of multiple myeloma.</p>Formula:C27H40N4O5Purity:100.00%Color and Shape:SolidMolecular weight:500.63Curculigoside
CAS:<p>1.</p>Formula:C22H26O11Purity:99.85%Color and Shape:SolidMolecular weight:466.44Itacitinib
CAS:<p>Itacitinib (INCB039110) is an orally bioavailable inhibitor of Janus-associated kinase 1 (JAK1) with potential antineoplastic activity.</p>Formula:C26H23F4N9OPurity:96.4% - 99.5%Color and Shape:SolidMolecular weight:553.51MPT0G211 mesylate
CAS:<p>MPT0G211 mesylate: potent, selective HDAC6 inhibitor (IC50=0.291nM), oral, BBB-penetrating, anti-tau and metastasis, potential anticancer.</p>Formula:C18H19N3O5SColor and Shape:SolidMolecular weight:389.43CPI203
CAS:<p>CPI203 (CPI 203) is an effective BET bromodomain inhibitor (IC50: 37 nM for BRD4).</p>Formula:C19H18ClN5OSPurity:99.13% - 99.77%Color and Shape:SolidMolecular weight:399.9UPF 1069
CAS:<p>UPF 1069 is a specific PARP2 inhibitor ( IC50: 0.3 μM). It is ~27-fold selective against PARP1.</p>Formula:C17H13NO3Purity:98.80% - 99.88%Color and Shape:SolidMolecular weight:279.29ZM-447439
CAS:<p>ZM 447439 selectively inhibits Aurora A/B (IC50: 110/130 nM); 8x less effective on MEK1, Src, Lck; minimal impact on CDK1/2/4, Plk1, Chk1.</p>Formula:C29H31N5O4Purity:99.11% - 99.59%Color and Shape:Pale Yellow SolidMolecular weight:513.59Atractylenolide I
CAS:<p>Atractylenolide-I reduces inflammation, improves sepsis, liver, and kidney function, and enhances EOC cell sensitivity to paclitaxel.</p>Formula:C15H18O2Purity:97.55% - 99.92%Color and Shape:SolidMolecular weight:230.3JNJ-42041935
CAS:<p>JNJ-42041935 (HIF-PHD Inhibitor II) is a potent (pKi = 7.3-7.9), 2-oxoglutarate competitive, reversible, and selective inhibitor of PHD enzymes.</p>Formula:C12H6ClF3N4O3Purity:99.58% - ≥95%Color and Shape:SolidMolecular weight:346.65HJ-PI01
CAS:<p>HJ-PI01 (HJ-PI01) is a Pim-2 inhibitor. HJ-PI01 (HJ-PI01) induces apoptosis and autophagic cell death in triple-negative human breast cancer.</p>Formula:C14H11NO2Purity:98.92%Color and Shape:SolidMolecular weight:225.24Pacritinib
CAS:<p>Pacritinib (SB1518) (SB1518) is an effective and specific inhibitor of JAK2 and FLT3 (IC50: 23/22 nM, in cell-free assays).</p>Formula:C28H32N4O3Purity:99.25% - 99.49%Color and Shape:SolidMolecular weight:472.58ABBV-744
CAS:<p>ABBV-744 is a BDII-selective BET bromodomain inhibitor that inhibits BRD2/3/4. It is used in the research on inflammatory diseases, cancer, and AIDS.</p>Formula:C28H30FN3O4Purity:97.03% - >99.99%Color and Shape:SolidMolecular weight:491.55Chlorogenic Acid
CAS:<p>Chlorogenic acid is a natural phenol. Chlorogenic acid has anti-inflammatory, antitumor, and antimicrobial effects. Cost-effective and quality-assured.</p>Formula:C16H18O9Purity:98.84% - 99.67%Color and Shape:SolidMolecular weight:354.31GSK484 hydrochloride
CAS:<p>GSK484 hydrochloride (GTPL8577) is a reversible peptidyl-arginine deiminase 4 (PAD4) inhibitor.Cost-effective and quality-assured.</p>Formula:C27H32ClN5O3Purity:98.32% - 99.62%Color and Shape:SolidMolecular weight:510.03MRTX-1719
CAS:<p>MRTX-1719 is a potent and selective inhibitor of the PRMT5/MTA complex with an IC50 value of <10 nM against PRMT5/MTAMTAPDELSDMA cell lines.Cost-effective and quality-assured.</p>Formula:C23H18ClFN6O2Purity:98.27% - 99.18%Color and Shape:SolidMolecular weight:464.88Bisindolylmaleimide IV
CAS:<p>Bisindolylmaleimide IV is a protein kinase C (PKC) cell permeable inhibitor( IC50 : 0.10 - 0.55 μM)</p>Formula:C20H13N3O2Purity:98.83%Color and Shape:Dark Red SolidMolecular weight:327.34Ilorasertib
CAS:<p>Ilorasertib (ABT-348) inhibits Aurora kinases A/B/C & RET, PDGFRβ, Flt1 (IC50: 1-120 nM).</p>Formula:C25H21FN6O2SPurity:96.17% - 97.49%Color and Shape:SolidMolecular weight:488.54AZ6102
CAS:<p>AZ6102: Potent TNKS1/2 inhibitor, 100x selective over PARPs, IC50 = 5 nM in DLD-1 Wnt pathway.</p>Formula:C25H28N6OPurity:97.98% - 99.91%Color and Shape:SolidMolecular weight:428.53PKC-iota inhibitor 1
CAS:<p>PKC-iota inhibitor 1 is an inhibitor of protein kinase C-iota (PKC-ι ; IC50 : 0.34 μM)</p>Formula:C21H22N6OPurity:98.82%Color and Shape:SolidMolecular weight:374.44RBN012759
CAS:<p>RBN012759 inhibits PARP14 protein and is more than 300-fold selective over all PARP family members.Cost-effective and quality-assured.</p>Formula:C19H23FN2O3SPurity:98.87% - 99.96%Color and Shape:SolidMolecular weight:378.46Pacritinib hydrochloride
CAS:<p>Pacritinib HCl: strong JAK2/Wild-type & JAK2V617F inhibitor (IC50: 23/19 nM), used in AML & MF research.</p>Formula:C28H32N4O3·xClHColor and Shape:SolidMS436
CAS:<p>MS436 is a selective, small-molecule inhibitor for the BRD4 bromodomains.</p>Formula:C18H17N5O3SPurity:97.95% - 98.92%Color and Shape:SolidMolecular weight:383.42OAC1
CAS:<p>OAC1 (BAS 00287861) activates Oct4, boosts iPSC efficiency, and speeds up reprogramming.</p>Formula:C14H11N3OPurity:99.49% - 99.65%Color and Shape:SolidMolecular weight:237.26Fraxinellone
CAS:<p>1.</p>Formula:C14H16O3Purity:99.35% - 99.92%Color and Shape:SolidMolecular weight:232.27TFMB-(R)-2-HG
CAS:<p>TFMB-(R)-2-HG, a carcinogen in AML, hinders SCF ER-Hoxb8 differentiation after estrogen loss.</p>Formula:C13H11F3O4Purity:97.15%Color and Shape:SolidMolecular weight:288.22(Z)-LFM-A13
CAS:<p>(Z)-LFM-A13(IC50=2.5 μM), a specific Bruton's tyrosine kinase (BTK), is more than 100-fold specificity than other protein kinases, such as JAK1, JAK2, HCK, EGFR, and IRK.</p>Formula:C11H8Br2N2O2Purity:99.88%Color and Shape:SolidMolecular weight:360SGC-SMARCA-BRDVIII
CAS:<p>SGC-SMARCA-BRDVIII is a potent and selective inhibitor of SMARCA2, SMARCA4, PB1(2), PB1(3) and PB1(5) with Kds of 35 nM, 36 nM, 3.7 μM, 2.0 μM and 13 nM,</p>Formula:C19H25N5O3Purity:99.54% - 99.92%Color and Shape:SolidMolecular weight:371.43Pim1/AKK1-IN-1
CAS:<p>Pim1/AKK1-IN-1: LKB1/AAK1 inhibitor with Kd 35/53/75/380 nM for Pim1/AKK1/MST2/LKB1, also targets MPSK1, TNIK.</p>Formula:C20H13N5OPurity:97.03% - 98.69%Color and Shape:SolidMolecular weight:339.35Hispidulin
CAS:<p>Hispidulin, a natural flavone with a broad spectrum of biological activities, is a Pim-1 inhibitor (IC50: 2.71 μM).</p>Formula:C16H12O6Purity:98.53% - 99.87%Color and Shape:SolidMolecular weight:300.26Iniparib
CAS:<p>Iniparib (BSI-201) (BSI-201) , a PARP1 inhibitor, exhibits potency in triple-negative breast Y (TNBC).</p>Formula:C7H5IN2O3Purity:98.93%Color and Shape:SolidMolecular weight:292.03SMI-16a
CAS:<p>SMI-16a (PIM1/2 Kinase Inhibitor VI) , a cell-permeable thiazolidinedione compound, acts as an effective, ATP-competitive inhibitor against Pim-1/2 kinases (</p>Formula:C13H13NO3SPurity:99.99%Color and Shape:SolidMolecular weight:263.31AT9283
CAS:<p>AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, Aurora B and Abl(T315I).</p>Formula:C19H23N7O2Purity:99.83% - 99.98%Color and Shape:SolidMolecular weight:381.43NI-57
CAS:<p>NI-57 inhibits BRPF family proteins: BRPF1 (IC50=3.1nM), BRPF2 (IC50=46nM), BRPF3 (IC50=140nM).</p>Formula:C19H17N3O4SPurity:99.88% - >99.99%Color and Shape:SolidMolecular weight:383.42Menin-MLL inhibitor MI-2
CAS:<p>Menin-MLL inhibitor MI-2 (MI2) is a potent menin-MLL interaction inhibitor with IC50 of 446 nM.</p>Formula:C18H25N5S2Purity:97.46%Color and Shape:SolidMolecular weight:375.55RVX-297
CAS:<p>RVX-297 selectively inhibits BD2 domains of BET bromodomains, binding preferentially to BET proteins.</p>Formula:C24H29N3O4Purity:99.62%Color and Shape:SolidMolecular weight:423.5RK-287107
CAS:<p>RK-287107 is an effective and specific inhibitor of tankyrase (IC50s: 14.3 and 10.6 nM for tankyrase-1 and tankyrase-2, respectively).</p>Formula:C22H26F2N4O2Purity:99.64%Color and Shape:SolidMolecular weight:416.46BRD4 Inhibitor 30
CAS:<p>4-(2-fluorophenyl)-1,3-thiazol-2-one: has anti-inflammatory, antibacterial, antifungal, and antitumor properties.</p>Formula:C9H6FNOSPurity:99.68%Color and Shape:SolidMolecular weight:195.21EED226
CAS:<p>EED226 is a potent, selective, and orally bioavailable embryonic ectoderm development (EED) inhibitor with an IC50 of 22 nM.</p>Formula:C17H15N5O3SPurity:98.14% - 99.33%Color and Shape:SolidMolecular weight:369.4Ro 31-8220 Mesylate
CAS:<p>Ro 31-8220 Mesylate (Bisindolylmaleimide IX mesylate) is a pan-PKC inhibitor, and also shows potent inhibition against MSK1, MAPKAP-K1b, S6K1, and GSK3β.</p>Formula:C25H23N5O2S·CH4O3SPurity:98.79% - 99.02%Color and Shape:SolidMolecular weight:553.65PF-06726304
CAS:<p>PF-06726304: potent EZH2 inhibitor, effective against tumors, Kis at 0.7 nM (wild-type) and 3.0 nM (Y641N mutant).</p>Formula:C22H21Cl2N3O3Purity:98.19% - 99.51%Color and Shape:SolidMolecular weight:446.33AZ505
CAS:<p>AZ505 is an effective and specific SMYD2 inhibitor (IC50: 0.12 μM).</p>Formula:C29H38Cl2N4O4Purity:98.18%Color and Shape:SolidMolecular weight:577.54Reversine
CAS:<p>Reversine, a small synthetic purine analogue (2, 6-disubstituted purine), is a potent inhibitior of Aurora A/B/C(IC50s=150-500 nM).</p>Formula:C21H27N7OPurity:98% - 98.42%Color and Shape:SolidMolecular weight:393.49MLN8054
CAS:<p>MLN8054 is a potent and selective Aurora A kinase inhibitor with an IC50 of 4 nM.</p>Formula:C25H15ClF2N4O2Purity:98.07% - 98.26%Color and Shape:SolidMolecular weight:476.86SETDB1-TTD-IN-1
CAS:<p>SETDB1-TTD-IN-1 is a potent and selective inhibitor of SET domain bifurcated protein 1 tandem tudor domain (SETDB1-TTD, Kd = 88 nM).Cost-effective and quality-assured.</p>Formula:C28H31N5O2Purity:98.26% - 99.96%Color and Shape:SolidMolecular weight:469.58GSK1379725A
CAS:<p>GSK1379725A is a selective BPTF ligand (Kd = 2.8 μM).</p>Formula:C23H23FN6O3Purity:99.51%Color and Shape:SolidMolecular weight:450.47Bromosporine
CAS:<p>Bromosporine is a broad spectrum inhibitor for bromodomains for BRD2/4/9 and CECR2 (IC50: 0.41/0.29/0.122/0.017 μM), respectively.</p>Formula:C17H20N6O4SPurity:99.65% - 99.79%Color and Shape:SolidMolecular weight:404.444-amino-1,8-Naphthalimide
CAS:<p>4-amino-1,8-Naphthalimide (4-ANI) is a PARP inhibitor with IC50 of 180 nM</p>Formula:C12H8N2O2Purity:95.13%Color and Shape:Yellow Solid PowderMolecular weight:212.2ORY1001
CAS:<p>ORY1001: Oral LSD1/KDM1A inhibitor, highly selective, IC50 <20 nM.</p>Formula:C15H22N2·2HClPurity:99.85% - 99.96%Color and Shape:SolidMolecular weight:303.27Ruboxistaurin mesylate
CAS:<p>Ruboxistaurin: PKC beta inhibitor, eases oxidative stress, heart issues & nephropathy in diabetic rats, halts retinal neovascularization.</p>Formula:C29H32N4O6SPurity:98%Color and Shape:SolidMolecular weight:564.65TP-064
CAS:<p>TP-064: Potent, selective PRMT4 inhibitor, IC50 < 10nM for H3 methylation, 100x selectivity, blocks MED12 methylation at 43nM.</p>Formula:C28H34N4O2Purity:97.85%Color and Shape:SolidMolecular weight:458.6LLY-507
CAS:<p>LLY-507 is an effective, cell-active, and specific inhibitor of protein-lysine Methyltransferase SMYD2.</p>Formula:C36H42N6OPurity:99.58% - 99.93%Color and Shape:SolidMolecular weight:574.76Picolinamide
CAS:<p>Picolinamide (Picolinoylamide) is found to be a strong inhibitor of poly (ADP-ribose) synthetase of nuclei from rat pancreatic islet cells.</p>Formula:C6H6N2OPurity:99.6%Color and Shape:SolidMolecular weight:122.12UNC1999
CAS:<p>UNC1999 is a orally bioavailable, effective and specific inhibitor of EZH2 (IC50=2 nM) and EZH1 (IC50=45).</p>Formula:C33H43N7O2Purity:99.19% - >99.99%Color and Shape:SolidMolecular weight:569.74AT-9283 HCl
CAS:<p>AT-9283, a multi-targeted kinase inhibitor, is used potentially for the treatment of multiple myeloma.</p>Formula:C19H24ClN7O2Color and Shape:SolidMolecular weight:417.89KDM4D-IN-1
CAS:<p>KDM4D-IN-1 is a KDM4D inhibitor (IC50: 0.41±0.03 μM).</p>Formula:C11H7N5OPurity:99.51% - >99.99%Color and Shape:SolidMolecular weight:225.21JMJD7-IN-1
CAS:<p>JMJD7-IN-1 (Benzoic acid, 2,4-dichloro-, 5-nitro-8-quinolinyl ester) is a potent JMJD7 inhibitor, with an IC50 of 6.62 μM.</p>Formula:C16H8Cl2N2O4Purity:99.66%Color and Shape:SolidMolecular weight:363.15Naphthol AS-E
CAS:<p>Naphthol AS-E (nAS-E) is an the KIX-KID interaction and CREB-mediated gene transcription inhibitor.</p>Formula:C17H12ClNO2Purity:99.33%Color and Shape:Grey Solid PowderMolecular weight:297.748-CHLOROQUINAZOLIN-4(1H)-ONE
CAS:<p>8-CHLOROQUINAZOLIN-4(1H)-ONE is inhibitor of Poly [ADP-ribose] polymerase 1 (human)</p>Formula:C8H5ClN2OPurity:98.79%Color and Shape:SolidMolecular weight:180.59ICG001
CAS:<p>ICG001 antagonizes Wnt signaling, binds CBP with 3 μM IC50, not p300.</p>Formula:C33H32N4O4Purity:99.06% - 99.95%Color and Shape:SolidMolecular weight:548.63(R)-(-)-JQ1 Enantiomer
CAS:<p>(R)-(-)-JQ1 Enantiomer is the stereoisomer of (+)-JQ1. (+)-JQ1 is a BET bromodomain inhibitor, acting on BRD4(1/2)(IC50 of 77 nM/33 nM in a cell-free assay)</p>Formula:C23H25ClN4O2SPurity:99.38%Color and Shape:SolidMolecular weight:456.99AZ9482
CAS:<p>AZ9482, a potent PARP inhibitor with 2-piperazinyl-3-cyano-pyridine linkage, causes centrosome declustering in HeLa cells with an EC50 < 18 nM.</p>Formula:C26H22N6O2Purity:99.18% - 99.86%Color and Shape:SolidMolecular weight:450.49JQEZ5
CAS:<p>JQEZ5 is an inhibitor of EZH2 lysine methyltransferase (IC50 = 11.1 nM).</p>Formula:C30H38N8O2Purity:98.14% - ≥98%Color and Shape:SolidMolecular weight:542.68Rucaparib hydrochloride
CAS:<p>Rucaparib hydrochloride (AG014699) is an oral PARP inhibitor with Ki 1.4 nM for PARP1 and hinders H6PD, studied in CRPC research.</p>Formula:C19H19ClFN3OColor and Shape:SolidMolecular weight:359.83XMD8-92
CAS:<p>XMD8-92 is an effective and specific BMK1/ERK5 inhibitor (Kd: 80 nM).</p>Formula:C26H30N6O3Purity:98.21%Color and Shape:SolidMolecular weight:474.55Rucaparib acetate
CAS:<p>Rucaparib acetate, an oral PARP-1, -2, -3 inhibitor (Ki 1.4 nM for PARP1), also moderately inhibits H6PD; promising for CRPC research.</p>Formula:C21H22FN3O3Color and Shape:SolidMolecular weight:383.423IOX1
CAS:<p>IOX1, a broad-spectrum 2OG oxygenase inhibitor, IC50: KDM4A - 0.6uM, KDM3A - 0.1uM.</p>Formula:C10H7NO3Purity:99.67%Color and Shape:SolidMolecular weight:189.17Menin-MLL inhibitor 20
CAS:<p>Menin-MLL inhibitor 20 is an irreversible inhibitor of menin-MLL interaction with antitumor activities.</p>Formula:C33H40N8O4Purity:97.77%Color and Shape:SolidMolecular weight:612.72γ-Oryzanol
CAS:<p>γ-Oryzanol (Gamma-Oryzanol) is a natural nutrient extract isolated from rice bran oil that contains a mixture of sterols and ferulic acids, which may aid in the</p>Formula:C40H58O4Purity:mixture - mixtureColor and Shape:White Or White Crystalline Powder OdourlessMolecular weight:602.9Ethyl 3,4-dihydroxybenzoate
CAS:<p>Ethyl 3,4-dihydroxybenzoate (EDHB): a prolyl hydroxylase inhibitor attenuates acute hypobaric hypoxia mediated vascular leakage in brain.</p>Formula:C9H10O4Purity:99.88%Color and Shape:White Crystal Or PowderMolecular weight:182.17Ruboxistaurin
CAS:<p>Ruboxistaurin (LY333531) is a selective PKC beta inhibitor, Ki 2 nM, inhibits beta I/II (IC50: 4.7/5.9 nM), orally active.</p>Formula:C28H28N4O3Color and Shape:SolidMolecular weight:468.552,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide
CAS:<p>2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide (GDC046), a potent lead analog, has good kinase selectivity and physicochemical properties.</p>Formula:C16H13Cl2N3O2Purity:98.77%Color and Shape:SolidMolecular weight:350.2EB-47 dihydrochloride
CAS:<p>EB 47 is an effective inhibitor of PARP-1 (IC50: 45 nM).</p>Formula:C24H29Cl2N9O6Color and Shape:SolidMolecular weight:610.45SC-43
CAS:<p>SC-43 is a potent and orally active agonist of SHP-1 (PTPN6).</p>Formula:C21H13ClF3N3O2Purity:98.44%Color and Shape:SolidMolecular weight:431.8WM-8014
CAS:<p>WM-8014 (MOZ-IN-3) is an inhibitor of MOZ(IC50=55 nM), a member of histone acetyltransferases.</p>Formula:C20H17FN2O3SPurity:99.64%Color and Shape:SolidMolecular weight:384.42MS31 trihydrochloride
<p>MS31 trihydrochloride: a selective SPIN1 inhibitor, binds H3K4me3 (IC50: 77-243 nM), non-toxic to healthy cells.</p>Formula:C20H30Cl3N3O2Color and Shape:SolidMolecular weight:450.83Ro 31-8220
CAS:<p>Ro 31-8220: potent PKC inhibitor (IC50: 5-27 nM). Affects MAPKAP-K1b, MSK1, S6K1, GSK3β (IC50: 3-38 nM), not MKK3/4/6/7.</p>Formula:C25H23N5O2SColor and Shape:SolidMolecular weight:457.55Remodelin hydrobromide
CAS:<p>Remodelin hydrobromide (Remodelin HBR) is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10.</p>Formula:C15H15BrN4SPurity:97.22% - 99.84%Color and Shape:SolidMolecular weight:363.275BAY-598
CAS:<p>BAY 598 is a potent and selective competitive inhibitor of SMYD2, exhibiting >100-fold selectivity over SMYD3, SUV420H1, and SUV420H2. Cost-effective and quality-assured.</p>Formula:C22H20Cl2F2N6O3Purity:99.18% - 99.78%Color and Shape:SolidMolecular weight:525.346-Bromo-3-methyl-1,4-dihydroquinazolin-2-one
CAS:<p>CHEMBRDG-BB 7118966 is an inhibitor of Bromodomain-containing protein 4 (human).</p>Formula:C9H9BrN2OPurity:99.28%Color and Shape:SolidMolecular weight:241.08Izilendustat hydrochloride
CAS:<p>Izilendustat hydrochloride inhibits prolyl hydroxylase, stabilizing HIF-1α/HIF-2, with potential to treat various HIF-1α diseases.</p>Formula:C22H29Cl2N3O4Color and Shape:SolidMolecular weight:470.39Paris saponin VII
CAS:<p>Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.</p>Formula:C51H82O21Purity:99.51% - 99.63%Color and Shape:SolidMolecular weight:1031.18PF-9366
CAS:<p>PF-9366 is a human methionine adenosyltransferase 2A (Mat2A) inhibitor (IC50: 420 nM; Kd: 170 nM).</p>Formula:C20H19ClN4Purity:97.28% - 99.88%Color and Shape:SolidMolecular weight:350.84Abrocitinib
CAS:<p>Abrocitinib (PF-04965842) (PF-04965842) is a potent, specific and orally-active JAK1 inhibitor (IC50s: 29/803 nM for JAK1/2).</p>Formula:C14H21N5O2SPurity:99.09% - 99.91%Color and Shape:SolidMolecular weight:323.41SNS-314
CAS:<p>SNS-314 inhibits Aurora kinases A and B, blocking cell division in AK-overexpressing tumors.</p>Formula:C18H15ClN6OS2Purity:98%Color and Shape:SolidMolecular weight:430.93PF 477736
CAS:<p>PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (</p>Formula:C22H25N7O2Purity:97.58% - 99.94%Color and Shape:SolidMolecular weight:419.48Peficitinib
CAS:<p>Peficitinib (ASP015K) (ASP015K, JNJ-54781532) is an orally bioavailable JAK inhibitor. Phase 3.</p>Formula:C18H22N4O2Purity:98.67% - 99.4%Color and Shape:SolidMolecular weight:326.39Phthalazinone pyrazole
CAS:<p>Phthalazinone pyrazole: a potent, selective oral Aurora-A kinase inhibitor, overexpressed in tumors with oncogenic activity.</p>Formula:C18H15N5OPurity:97.03%Color and Shape:SolidMolecular weight:317.34653-47
CAS:<p>653-47 enhances the effects of 666-15 on inhibiting CREB and is a mild CREB inhibitor itself (IC50: 26.3μM).</p>Formula:C20H19ClN2O3Color and Shape:SolidMolecular weight:370.83WHI-P97
CAS:<p>WHI-P97 is a rationally designed potent inhibitor of JAK-3.</p>Formula:C16H13Br2N3O3Purity:99.93%Color and Shape:SolidMolecular weight:455.1Daphnetin
CAS:<p>Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),</p>Formula:C9H6O4Purity:97.47% - 99.8%Color and Shape:SolidMolecular weight:178.14Pyridone 6
CAS:<p>Pyridone 6, a selective JAK1/2/3 and Tyk2 inhibitor with IC50s: JAK1=15 nM, JAK2=1 nM, JAK3 (Ki=5 nM), Tyk2=1 nM; weakly binds other kinases (130 nM-10 μM).</p>Formula:C18H16FN3OPurity:97.1% - 98.74%Color and Shape:SolidMolecular weight:309.34GN44028
CAS:<p>GN44028 is a HIF-1 inhibitor with an IC50 of 14 nM, stopping HIF-1α activity but not mRNA or protein levels, or dimerization.</p>Formula:C18H15N3O2Purity:99.52%Color and Shape:SolidMolecular weight:305.33XAV-939
CAS:<p>XAV-939 (NVP-XAV939) shows the selective inhibition against Wnt/β-catenin-mediated transcription by tankyrase1/2 inhibition (IC50: 11/4 nM in cell-free assay).</p>Formula:C14H11F3N2OSPurity:97.47% - 99.67%Color and Shape:SolidMolecular weight:312.311,5-Isoquinolinediol
CAS:<p>1,5-Isoquinolinediol, a PARP1 inhibitor (IC50: 0.39 μM), is used in DNA repair and cell death studies.</p>Formula:C9H7NO2Purity:98.29% - 99.35%Color and Shape:Of White To White PowderMolecular weight:161.16MS7972
CAS:<p>MS7972 is CREBBP inhibitor that blocks human p53 and CREB binding protein association. MS7972 can almost completely block this BRD interaction at 50 μM</p>Formula:C14H13NO2Purity:99.78%Color and Shape:SolidMolecular weight:227.26Molibresib
CAS:<p>Molibresib (GSK525762) is an inhibitor of BET proteins (IC50: about 35 nM).</p>Formula:C22H22ClN5O2Purity:97.70% - 99.08%Color and Shape:SolidMolecular weight:423.9dCBP-1
CAS:<p>dCBP-1 selectively degrades p300/CBP via CRBN, killing multiple myeloma cells.</p>Formula:C51H63F2N11O10Purity:98.21% - 99.12%Color and Shape:SolidMolecular weight:1028.11GSK 690 Hydrochloride
CAS:<p>GSK 690 (Hydrochloride) is a reversible lysine specific demethylase 1 (LSD1) inhibitor with a Kd value of 9 nM and IC 50 of 37 nM.</p>Formula:C24H24ClN3OPurity:98%Color and Shape:SolidMolecular weight:405.92
