DNA Damage/DNA Repair
DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.
Subcategories of "DNA Damage/DNA Repair"
- ATM/ATR(71 products)
- DNA Alkylation(11 products)
- DNA Methyltransferase(422 products)
- DNA gyrase(11 products)
- DNA-PK(50 products)
- MTH1(1 products)
- Nucleoside Antimetabolite/Analog(1,388 products)
- Reverse Transcriptase(43 products)
- Sirtuin(88 products)
- Telomerase(33 products)
- Topoisomerase(136 products)
Show 3 more subcategories
Found 963 products of "DNA Damage/DNA Repair"
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Adefovir
CAS:<p>Adefovir: acyclic nucleoside phosphonate, reverse transcriptase inhibitor for hepatitis B and herpes treatment.</p>Formula:C8H12N5O4PPurity:99.56%Color and Shape:White To Off-White PowderMolecular weight:273.19PJ34 hydrochloride
CAS:<p>PJ34 hydrochloride (PJ34 HCl) is a potent specific inhibitor of PARPl/2.</p>Formula:C17H18ClN3O2Purity:98.87% - ≥95%Color and Shape:SolidMolecular weight:331.8SRT 2104
CAS:<p>SRT 2104 (GSK2245840) is a selective and brain-permeable SIRT1 activator.</p>Formula:C26H24N6O2S2Purity:98.34% - 99.82%Color and Shape:SolidMolecular weight:516.64Leniolisib
CAS:<p>Leniolisib (CDZ173) (CDZ173) is a potent and selective PI3Kδ inhibitor (IC50: 11 nM).</p>Formula:C21H25F3N6O2Purity:99.88%Color and Shape:SolidMolecular weight:450.46Palifosfamide
CAS:<p>Palifosfamide lysine (ZIO-201) stable, effective vs. sarcomas in vitro. IC50: 2.25-6.75 μM, except OS222 at 31.5 μM.</p>Formula:C4H11Cl2N2O2PPurity:99.72%Color and Shape:SolidMolecular weight:221.02360A
CAS:<p>360A is a stabilizing G-Quadruplex ligand, and also inhibits telomerase activity for telomerase in TRAP-G4 assay(IC50 : 300 nM).</p>Formula:C27H23N5O2Purity:98.68%Color and Shape:SolidMolecular weight:449.5Lomeguatrib
CAS:<p>Lomeguatrib (PaTrin-2), a modified guanine base, inhibits the activity of DNA repair protein O(6)-alkylguanine-DNA alkyltransferase (MGMT) .</p>Formula:C10H8BrN5OSPurity:99.26% - >99.99%Color and Shape:SolidMolecular weight:326.17Nexturastat A
CAS:<p>Nexturastat A is an effective and specific HDAC6 inhibitor (IC50: 5 nM). Its selectivity is >190-fold than other HDACs.</p>Formula:C19H23N3O3Purity:99.40% - 99.57%Color and Shape:SolidMolecular weight:341.4ETP-45658
CAS:<p>ETP-45658 (ETP45658) is a PI 3-kinase inhibitor (IC50 values are 22, 30, 129 and 710 nM for PI 3-Kα, PI 3-Kδ, PI 3-Kβ and PI 3-Kγ respectively).</p>Formula:C16H17N5O2Purity:99.14%Color and Shape:SolidMolecular weight:311.34Dactolisib
CAS:<p>Dactolisib (BEZ235) is an orally bioavailable inhibitor of PI3K and mTOR (IC50s: 4 nM/5 nM/7 nM/75 nM, and 20.7 nM for p110α/p110γ/p110δ/p110β and mTOR).</p>Formula:C30H23N5OPurity:97.64% - 99.85%Color and Shape:SolidMolecular weight:469.54Pimelic diphenylamide 106
CAS:<p>Pimelic diphenylamide 106 (RGFA-8) is a slow, tight-binding inhibitor of class I HDAC, showing no activity against class II HDACs.</p>Formula:C20H25N3O2Purity:95.25% - 99.28%Color and Shape:SolidMolecular weight:339.43TMP269
CAS:<p>TMP269: Class IIa HDAC inhibitor; HDAC4 IC50=157 nM, HDAC5 IC50=97 nM, HDAC7 IC50=43 nM, HDAC9 IC50=23 nM.</p>Formula:C25H21F3N4O3SPurity:98% - 99.72%Color and Shape:SolidMolecular weight:514.52Amonafide
CAS:<p>Amonafide (NSC-308847, AS1413) causes DNA breaks via topoisomerase II, not topoisomerase I.</p>Formula:C16H17N3O2Purity:99.39%Color and Shape:SolidMolecular weight:283.336-AZATHYMINE
CAS:<p>6-azathymine inhibits D-3-aminoisobutyrate-pyruvate aminotransferase; 6-azauracil competes with beta-alanine, uncompetitive with pyruvic acid, Ki ~8.9 mM.</p>Formula:C4H5N3O2Purity:99.47%Color and Shape:SolidMolecular weight:127.1ACY-775
CAS:<p>ACY-775 is an effective and specific inhibitor of HDAC6 (IC50: 7.5 nM).</p>Formula:C17H19FN4O2Purity:97.67% - 98.83%Color and Shape:SolidMolecular weight:330.36Satraplatin
CAS:<p>Satraplatin (BMS182751) is an orally available antineoplastic platinum(IV) complex.Satraplatin has a favorable toxicity profile and appears to have clinical</p>Formula:C10H22Cl2N2O4PtPurity:98.25%Color and Shape:SolidMolecular weight:500.28CRT0044876
CAS:<p>CRT0044876 (7-NO2-ICA) is a potent and selective APE1 inhibitor with IC50 of ~3 μM.</p>Formula:C9H6N2O4Purity:98.27% - 98.98%Color and Shape:Brown PowderMolecular weight:206.15azd1390
CAS:<p>AZD1390: Potent ATM inhibitor (IC50: 0.78 nM), >10,000-fold selectivity vs. PIKK enzymes.</p>Formula:C27H32FN5O2Purity:97.41% - 99.72%Color and Shape:SolidMolecular weight:477.57RGFP966
CAS:<p>RGFP966 is an HDAC3 inhibitor (IC50: 0.08 μM) and does not affect other HDACs at concentrations up to 15 μM.</p>Formula:C21H19FN4OPurity:99.2% - 99.88%Color and Shape:SolidMolecular weight:362.4RG2833
CAS:<p>RG2833 (RGFP109) (RGFP109), a brain-penetrant HDAC inhibitor, is with IC50 of 60 nM and 50 nM for HDAC1 and HDAC3, respectively.</p>Formula:C20H25N3O2Purity:99% - 99.50%Color and Shape:SolidMolecular weight:339.43
