DNA Damage/DNA Repair
DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.
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Subcategories of "DNA Damage/DNA Repair"
ATM/ATR
DNA Alkylation
DNA Methyltransferase
DNA gyrase
DNA-PK
MTH1
Nucleoside Antimetabolite/Analog
Reverse Transcriptase
Sirtuin
Telomerase
Topoisomerase
Show 3 more subcategories
Products of "DNA Damage/DNA Repair"
HDAC ligand-1
CAS:34840-28-3
HDAC ligand-1 is a synthetic precursor utilized in the production of PROTAC-based HDAC degraders [1].
Formula:
C7H8N2O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
136.15
Ref: TM-T79003
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Friday 24 Jan 2025
SIRT5 inhibitor 1
CAS:2166487-21-2
SIRT5 inhibitor 1 targets human Sirtuin 5 deacylase, with an IC50 of 0.11 μM, linked …
Formula:
C31H39FN6O6S2
Purity:
98.06%
Color and Shape:
Solid
Molecular weight:
674.81
Ref: TM-T12921
| 1mg | 145.00 € | ||
| 2mg | 206.00 € | ||
| 5mg | 351.00 € | ||
| 10mg | 527.00 € | ||
| 25mg | 927.00 € | ||
| 50mg | 1,333.00 € | ||
| 100mg | 1,782.00 € | ||
| 1mL*10mM (DMSO) | 463.00 € |
Estimated delivery in United States, on Friday 24 Jan 2025
Cedazuridine
CAS:1141397-80-9
Cedazuridine ((4R)-2'-Deoxy-2',2'-difluoro-3,4,5,6-tetrahydrouridine) is an oral inhibitor of cytidine deaminase with antineoplastic properties.
Formula:
C9H14F2N2O5
Purity:
99.46%
Color and Shape:
Solid
Molecular weight:
268.21
Ref: TM-T26972
| 1mg | 54.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 150.00 € | ||
| 25mg | 295.00 € | ||
| 50mg | 445.00 € | ||
| 1mL*10mM (DMSO) | 117.00 € |
Estimated delivery in United States, on Friday 24 Jan 2025
SIRT5 inhibitor 6
CAS:2834736-82-0
SIRT5 Inhibitor 6 is a potent, selective, and substrate-competitive inhibitor of SIRT5, exhibiting an IC50 …
Formula:
C21H28N6O4S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
460.55
Ref: TM-T78802
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Friday 24 Jan 2025
BRD2492
CAS:1821669-43-5
BRD2492 is an HDAC1 and HDAC2 inhibitor with antiproliferative activity, inhibits HDAC1/2 and induces apoptosis.
Formula:
C20H18N4O2
Purity:
99.56%
Color and Shape:
Solid
Molecular weight:
346.38
Ref: TM-T26897
| 1mg | 53.00 € | ||
| 5mg | 101.00 € | ||
| 10mg | 150.00 € | ||
| 25mg | 252.00 € | ||
| 50mg | 369.00 € | ||
| 100mg | 535.00 € |
Estimated delivery in United States, on Friday 24 Jan 2025
Mavodelpar free base
CAS:942594-93-6
Mavodelpar free acid (REN001 free acid) is an selective agonist of PPARδ.
Formula:
C31H30FNO5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
515.57
Ref: TM-T12527
| 5mg | 1,000.00 € | ||
| 50mg | 2,038.00 € | ||
| 100mg | 2,617.00 € |
Estimated delivery in United States, on Friday 24 Jan 2025
ATR-IN-23
CAS:2923800-62-6
ATR-IN-23 (Compound 34), a potent and selective ATR inhibitor, exhibits an IC50 of 1.5 nM, …
Formula:
C20H22N6O3S2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
458.56
Ref: TM-T78959
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Friday 24 Jan 2025
SAHA-OH
CAS:2857098-30-5
SAHA-OH selectively inhibits HDAC6 (IC50 = 23 nM) with 10-47x preference over HDACs 1, 2, …
Formula:
C15H22N2O4
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
294.35
Ref: TM-T73454
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Friday 24 Jan 2025
SIRT2-IN-9
CAS:522650-91-5
SIRT2-IN-9: selective SIRT2 inhibitor; IC50=1.3μM; halts MCF-7 cell growth; for cancer study.
Formula:
C21H22N6OS2
Purity:
99.5%
Color and Shape:
Liquid
Molecular weight:
438.57
Ref: TM-T62515
| 5mg | 74.00 € | ||
| 10mg | 114.00 € | ||
| 25mg | 230.00 € | ||
| 50mg | 364.00 € | ||
| 100mg | 546.00 € |
Estimated delivery in United States, on Friday 24 Jan 2025
PARP/PI3K-IN-1
CAS:2337386-47-5
PARP/PI3K-IN-1 is a PARP and PI3K dual inhibitor with anticancer and antiproliferative activities for the …
Formula:
C33H28F4N8O3
Purity:
99.59%
Color and Shape:
Solid
Molecular weight:
660.62
Ref: TM-T12365
| 1mg | 95.00 € | ||
| 5mg | 237.00 € | ||
| 10mg | 368.00 € | ||
| 25mg | 640.00 € | ||
| 50mg | 993.00 € | ||
| 100mg | 1,345.00 € |
Estimated delivery in United States, on Friday 24 Jan 2025
MPT0G211
CAS:2151853-97-1
MPT0G211: oral HDAC6 inhibitor with IC50=0.291 nM, 1000x selectivity, neuroprotective, anti-metastatic, crosses blood-brain barrier for …
Formula:
C17H15N3O2
Purity:
99% - 99.91%
Color and Shape:
Liquid
Molecular weight:
293.32
Ref: TM-T60616
| 1mg | 95.00 € | ||
| 2mg | 144.00 € | ||
| 5mg | 230.00 € | ||
| 10mg | 374.00 € | ||
| 25mg | 611.00 € | ||
| 50mg | 860.00 € | ||
| 100mg | 1,151.00 € | ||
| 500mg | 2,320.00 € | ||
| 1mL*10mM (DMSO) | 257.00 € |
Estimated delivery in United States, on Friday 24 Jan 2025
Topoisomerase IV inhibitor 2
CAS:2883403-36-7
Compound 5d, a potent TOPO IV inhibitor (IC50: 0.35 μM), also inhibits DNA gyrase (IC50: …
Formula:
C33H30FN7O6S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
671.7
Ref: TM-T72154
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Friday 24 Jan 2025
SS-208
CAS:2245942-72-5
SS-208 is a selective inhibitor of HDAC6 (IC50 = 12 nM) with anti-tumor activity. SS-208 …
Formula:
C13H11Cl2N3O4
Purity:
99.07%
Color and Shape:
Solid
Molecular weight:
344.15
Ref: TM-T16936
| 1mg | 87.00 € | ||
| 5mg | 185.00 € | ||
| 10mg | 294.00 € | ||
| 25mg | 512.00 € | ||
| 50mg | 738.00 € | ||
| 100mg | 1,013.00 € |
Estimated delivery in United States, on Friday 24 Jan 2025
Resminostat
CAS:864814-88-0
Resminostat (4SC-201) is an orally bioavailable inhibitor of histone deacetylases (HDACs) with potential antineoplastic activity.
Formula:
C16H19N3O4S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
349.4
Ref: TM-T6637
| 5mg | 95.00 € | ||
| 10mg | 168.00 € | ||
| 25mg | 298.00 € | ||
| 50mg | 539.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Friday 24 Jan 2025
PARP10-IN-2
CAS:1042780-52-8
PARP10-IN-2 is a potent inhibitor of PARP10, a mono-ADP-ribosyltransferase, with an IC50 value of 3.64 …
Formula:
C14H10N2O2
Purity:
99.68%
Color and Shape:
Liquid
Molecular weight:
238.24
Ref: TM-T73007
| 5mg | 69.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 172.00 € | ||
| 50mg | 305.00 € | ||
| 100mg | 500.00 € | ||
| 500mg | 1,068.00 € |
Estimated delivery in United States, on Friday 24 Jan 2025
Givinostat hydrochloride monohydrate
CAS:732302-99-7
Givinostat hydrochloride monohydrate (ITF2357) is an HDAC inhibitor.
Formula:
C24H27N3O4·HCl·H2O
Purity:
97.97% - 98.09%
Color and Shape:
Solid
Molecular weight:
475.97
Ref: TM-T6279
| 5mg | 50.00 € | ||
| 10mg | 83.00 € | ||
| 25mg | 146.00 € | ||
| 50mg | 257.00 € | ||
| 100mg | 379.00 € | ||
| 200mg | 539.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Friday 24 Jan 2025
Guadecitabine sodium
CAS:929904-85-8
Guadecitabine sodium is a inhibitor of second-generation DNA methyltransferases (DNMT) .
Formula:
C18H24N9NaO10P
Purity:
98%
Color and Shape:
Solid
Molecular weight:
580.407
Ref: TM-T12790
| 25mg | 1,549.00 € | ||
| 50mg | 2,038.00 € | ||
| 100mg | 2,617.00 € |
Estimated delivery in United States, on Friday 24 Jan 2025
Sarmustine
CAS:81965-43-7
SarCNU is an alkylating anticancer drug targeting prostate cancer through p53 pathways and selects P140K …
Formula:
C6H11ClN4O3
Purity:
100% - 99.71%
Color and Shape:
Solid
Molecular weight:
222.63
Ref: TM-T28663
| 1mg | 185.00 € | ||
| 5mg | 456.00 € | ||
| 10mg | 653.00 € | ||
| 25mg | 1,020.00 € | ||
| 50mg | 1,406.00 € | ||
| 100mg | 1,859.00 € |
Estimated delivery in United States, on Friday 24 Jan 2025
BRD0539
CAS:1403838-79-8
BRD0539 is a cell-permeable spCas9 inhibitor that blocks the binding of spCas9 to DNA and …
Formula:
C25H25FN2O3S
Purity:
98.03%
Color and Shape:
Solid
Molecular weight:
452.54
Ref: TM-T22279
| 1mg | 185.00 € |
Estimated delivery in United States, on Friday 24 Jan 2025
BRD 9757
CAS:1423058-85-8
BRD 9757 (N-Hydroxy-1-cyclopentene-1-carboxamide) is a selective inhibitor of HDAC6 (IC50 = 30 nM).
Formula:
C6H9NO2
Purity:
99.57% - 99.69%
Color and Shape:
Solid
Molecular weight:
127.14
Ref: TM-T25175
| 1mg | 41.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 119.00 € | ||
| 25mg | 222.00 € | ||
| 50mg | 333.00 € | ||
| 100mg | 500.00 € | ||
| 500mg | 1,067.00 € |
Estimated delivery in United States, on Friday 24 Jan 2025
