DNA Damage/DNA Repair
DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.
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Subcategories of "DNA Damage/DNA Repair"
ATM/ATR
DNA Alkylation
DNA Methyltransferase
DNA gyrase
DNA-PK
MTH1
Nucleoside Antimetabolite/Analog
Reverse Transcriptase
Sirtuin
Telomerase
Topoisomerase
Show 3 more subcategories
Products of "DNA Damage/DNA Repair"
BMVC
CAS:627810-06-4
BMVC is a potent G-quadruplex (G4) stabilizer and a selective telomerase inhibitor (IC50: ~0.2 μM) …
Formula:
C28H25I2N3
Color and Shape:
Solid
Molecular weight:
657.33
Ref: TM-T10574
| 25mg | 850.00 € | ||
| 50mg | 1,114.00 € | ||
| 100mg | 1,741.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
Daniquidone
CAS:67199-66-0
Daniquidone (Batracylin) is a potent dual inhibitor of DNA topoisomerase I and DNA topoisomerase II …
Formula:
C15H11N3O
Purity:
98.59% - 99.52%
Color and Shape:
Solid
Molecular weight:
249.27
Ref: TM-T68896
| 1mg | 52.00 € | ||
| 5mg | 105.00 € | ||
| 10mg | 157.00 € | ||
| 25mg | 251.00 € | ||
| 50mg | 367.00 € | ||
| 100mg | 626.00 € | ||
| 500mg | 2,368.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
HDACs/mTOR Inhibitor 1
CAS:2271413-06-8
HDACs/mTOR Inhibitor 1 is a dual HDACs and mammalian target of Rapamycin (mTOR) target inhibitor …
Formula:
C28H38N8O5
Color and Shape:
Solid
Molecular weight:
566.65
Ref: TM-T11544
| 5mg | 418.00 € | ||
| 25mg | 1,327.00 € | ||
| 50mg | 1,741.00 € | ||
| 100mg | 2,340.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
DC_517
CAS:500017-70-9
DC_517 is an inhibitor of DNA methyltransferase 1 (DNMT1) ( IC50: 1.7 μM; Kd: 0.91 …
Formula:
C33H35N3O2
Color and Shape:
Solid
Molecular weight:
505.65
Ref: TM-T15081
| 2mg | 186.00 € | ||
| 25mg | 1,271.00 € | ||
| 50mg | 1,676.00 € | ||
| 100mg | 2,340.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
HDAC6 degrader 9c
CAS:2235382-05-3
HDAC6 degrader 9c is a small molecule histone deacetylase 6 (HDAC6) degrader that can be …
Formula:
C37H45N9O10
Purity:
100%
Color and Shape:
Solid
Molecular weight:
775.81
Ref: TM-T69753
| 1mg | 181.00 € | ||
| 5mg | 447.00 € | ||
| 10mg | 640.00 € | ||
| 25mg | 998.00 € | ||
| 50mg | 1,377.00 € | ||
| 100mg | 1,821.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
Sirt2-IN-1
CAS:1862238-00-3
Sirt2-IN-1 is an inhibitor of sirtuin 2 (IC50 = 163 nM).
Formula:
C28H27N7O2S2
Purity:
99.05% - 99.15%
Color and Shape:
Solid
Molecular weight:
557.69
Ref: TM-T12920
| 1mg | 103.00 € | ||
| 5mg | 210.00 € | ||
| 10mg | 333.00 € | ||
| 25mg | 531.00 € | ||
| 50mg | 719.00 € | ||
| 100mg | 917.00 € | ||
| 500mg | 1,838.00 € | ||
| 1mL*10mM (DMSO) | 265.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
L82
CAS:329227-30-7
L82: A selective, non-competitive DNA Lig1 inhibitor with anti-proliferative effects on breast cancer cells. IC50=12 …
Formula:
C11H8ClN5O4
Purity:
98.91% - 99%
Color and Shape:
Solid
Molecular weight:
309.67
Ref: TM-T60753
| 5mg | 69.00 € | ||
| 10mg | 101.00 € | ||
| 25mg | 183.00 € | ||
| 50mg | 293.00 € | ||
| 100mg | 462.00 € | ||
| 500mg | 1,003.00 € | ||
| 1mL*10mM (DMSO) | 76.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
MTH1-IN-2
CAS:901044-91-5
MTH1-IN-2 is an inhibitor of MutT homolog 1 (MTH1), with anti-tumor activity.
Formula:
C24H27N3O5S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
469.55
Ref: TM-T12122
| 25mg | 1,410.00 € | ||
| 50mg | 1,852.00 € | ||
| 100mg | 2,338.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
SIRT6-IN-5
CAS:891002-11-2
SIRT6-IN-5: potent, selective SIRT6 inhibitor; IC50=34 μM; immunosuppressive, enhances chemo, boosts H3K9 acetylation, glucose uptake, …
Formula:
C19H14N2O6
Purity:
98.84%
Color and Shape:
Solid
Molecular weight:
366.32
Ref: TM-T24793
| 1mg | 55.00 € | ||
| 5mg | 118.00 € | ||
| 10mg | 184.00 € | ||
| 25mg | 371.00 € | ||
| 50mg | 732.00 € | ||
| 100mg | 998.00 € | ||
| 500mg | 1,986.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
RK-9123016
CAS:955900-27-3
RK-9123016 is a SIRT2 inhibitor.
Formula:
C16H18N6O3S
Purity:
100%
Color and Shape:
Solid
Molecular weight:
374.42
Ref: TM-T28543
| 5mg | 54.00 € | ||
| 10mg | 81.00 € | ||
| 25mg | 124.00 € | ||
| 50mg | 179.00 € | ||
| 100mg | 267.00 € | ||
| 200mg | 401.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
DN-1289
DN-1289: oral, BBB-penetrating, selectively inhibits DLK (IC50=17nM) & LZK (IC50=40nM), blocks p-c-Jun in mouse optic …
Formula:
C18H19F4N7O2
Purity:
100%
Color and Shape:
Solid
Molecular weight:
441.38
Ref: TM-T73457
| 1mg | 327.00 € | ||
| 5mg | 901.00 € | ||
| 10mg | 1,121.00 € | ||
| 25mg | 1,486.00 € | ||
| 50mg | 1,838.00 € | ||
| 100mg | 2,321.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
Braco-19 trihydrochloride
CAS:1177798-88-7
BRACO19 3HCl inhibits telomerase, blocking its capping function, and prevents HAdV viral replication.
Formula:
C35H46Cl3N7O2
Purity:
98.74%
Color and Shape:
Solid
Molecular weight:
703.14
Ref: TM-T23819
| 1mg | 52.00 € | ||
| 5mg | 109.00 € | ||
| 10mg | 176.00 € | ||
| 25mg | 385.00 € | ||
| 50mg | 633.00 € | ||
| 100mg | 1,052.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
ACY-1083
CAS:1708113-43-2
ACY-1083 is a selective and brain-penetrating HDAC6 inhibitor (IC50: 3 nM) and effectively reverses chemotherapy-induced …
Formula:
C17H18F2N4O2
Purity:
98.97% - 99.22%
Color and Shape:
Solid
Molecular weight:
348.35
Ref: TM-T10244
| 1mg | 149.00 € | ||
| 5mg | 305.00 € | ||
| 10mg | 520.00 € | ||
| 25mg | 820.00 € | ||
| 50mg | 1,143.00 € | ||
| 100mg | 1,542.00 € | ||
| 500mg | 3,111.00 € | ||
| 1mL*10mM (DMSO) | 343.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
ACY-957
CAS:1609389-52-7
ACY-957: Oral HDAC1/2 inhibitor (IC50: HDAC1=7nM, HDAC2=18nM, HDAC3=1300nM); inactive on HDAC4/5/6/7/8/9.
Formula:
C24H23N5OS
Purity:
98.24%
Color and Shape:
Solid
Molecular weight:
429.54
Ref: TM-T10245
| 1mg | 94.00 € | ||
| 2mg | 143.00 € | ||
| 5mg | 238.00 € | ||
| 10mg | 295.00 € | ||
| 25mg | 452.00 € | ||
| 50mg | 640.00 € | ||
| 100mg | 841.00 € | ||
| 1mL*10mM (DMSO) | 264.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
PARP14 inhibitor H10
CAS:2084811-68-5
PARP14 inhibitor H10 is a selective inhibitor against PARP14 with IC50 of 490 nM
Formula:
C24H27N7O7S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
557.58
Ref: TM-T12366
| 1mg | 880.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
360A iodide
CAS:737763-37-0
360A iodide is a selective stabilizer of G-quadruplex and inhibits telomerase activity (IC50: 300 nM …
Formula:
C27H23I2N5O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
703.31
Ref: TM-T13504
| 50mg | 699.00 € | ||
| 100mg | 1,299.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
Exifone
CAS:52479-85-3
Exifone (NSC-680919) is a mixed, nonessential activator of HDAC1 that is capable of binding to …
Formula:
C13H10O7
Purity:
99.39% - 99.95%
Color and Shape:
Yellow Solid
Molecular weight:
278.21
Ref: TM-T20080
| 5mg | 59.00 € | ||
| 25mg | 85.00 € | ||
| 50mg | 115.00 € | ||
| 100mg | 171.00 € | ||
| 200mg | 248.00 € | ||
| 1mL*10mM (DMSO) | 56.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
CM-579
CAS:1846570-40-8
CM-579 is a dual inhibitor of G9a and DNMT( IC50:16 nM, 32 nM for G9a …
Formula:
C29H40N4O3
Purity:
99.62%
Color and Shape:
Solid
Molecular weight:
492.65
Ref: TM-T10840L
| 1mg | 34.00 € | ||
| 5mg | 62.00 € | ||
| 10mg | 90.00 € | ||
| 25mg | 130.00 € | ||
| 50mg | 181.00 € | ||
| 100mg | 273.00 € | ||
| 200mg | 397.00 € | ||
| 1mL*10mM (DMSO) | 81.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
Givinostat hydrochloride
CAS:199657-29-9
Givinostat HCl (ITF2357 HCl) inhibits HDAC1/3 (IC50: 198/157 nM) with anti-inflammatory, anti-angiogenic, and antineoplastic properties.
Formula:
C24H28ClN3O4
Purity:
98.01%
Color and Shape:
Solid
Molecular weight:
457.95
Ref: TM-T6279L
| 1mg | 73.00 € | ||
| 2mg | 92.00 € | ||
| 5mg | 131.00 € | ||
| 10mg | 211.00 € | ||
| 25mg | 443.00 € | ||
| 50mg | 651.00 € | ||
| 100mg | 926.00 € | ||
| 500mg | 1,848.00 € | ||
| 1mL*10mM (DMSO) | 206.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
MPT0G211
CAS:2151853-97-1
MPT0G211: oral HDAC6 inhibitor with IC50=0.291 nM, 1000x selectivity, neuroprotective, anti-metastatic, crosses blood-brain barrier for …
Formula:
C17H15N3O2
Purity:
99% - 99.91%
Color and Shape:
Solid
Molecular weight:
293.32
Ref: TM-T60616
| 1mg | 95.00 € | ||
| 2mg | 144.00 € | ||
| 5mg | 230.00 € | ||
| 10mg | 374.00 € | ||
| 25mg | 611.00 € | ||
| 50mg | 860.00 € | ||
| 100mg | 1,151.00 € | ||
| 500mg | 2,320.00 € | ||
| 1mL*10mM (DMSO) | 257.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
