DNA Damage/DNA Repair
DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.
Subcategories of "DNA Damage/DNA Repair"
- ATM/ATR(72 products)
- DNA Alkylation(20 products)
- DNA Methyltransferase(460 products)
- DNA gyrase(6 products)
- DNA-PK(49 products)
- MTH1(1 products)
- Nucleoside Antimetabolite/Analog(1,418 products)
- Reverse Transcriptase(42 products)
- Sirtuin(90 products)
- Telomerase(34 products)
- Topoisomerase(126 products)
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Found 885 products of "DNA Damage/DNA Repair"
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PPARγ agonist 6
CAS:PPARγ agonist 6 (Compound 12) is a potent agonist of selective PPARγ. PPARγ agonist 6 has potential for cancer disease research.Formula:C27H26N2O4Color and Shape:SolidMolecular weight:442.51DNA-PK-IN-7
CAS:DNA-PK-IN-7 is a potent DNA-PK inhibitor (IC50= 1 nM) (WO2021104277A1, compound 5).Formula:C19H21N9O2Color and Shape:SolidMolecular weight:407.435-Aza-4'-thio-2'-deoxycytidine
CAS:5-Aza-4'-thio-2'-deoxycytidine (5-Aza-T-dCyd), a sulfur-containing deoxy-cytidine analog, serves as an orally active inhibitor of DNA methyltransferase I (DNMT1). It exhibits potential antitumor effects and DNA hypomethylating properties [1].Formula:C8H12N4O3SColor and Shape:SolidMolecular weight:244.27PluriSIn #2
CAS:PluriSIn #2 is a selective topoisomerase II α (topo2α) transcription inhibitor exhibiting cytotoxicity towards undifferentiated, leukaemogenic hPSCs.Formula:C11H8FN3O3Purity:98% - 99.79%Color and Shape:SolidMolecular weight:249.2PPARα/δ agonist 1
CAS:PPARα/δ agonist 1 is a potent PPARα/PPARδ dual agonist with EC50 values of 7.0 nM for PPARα and 8.4 nM for PPARδ.Formula:C22H22F3N3O5Color and Shape:SolidMolecular weight:465.42Piroxantrone
CAS:Piroxantrone (CI942; PD111815) is an anthrapyrazole antibiotic that disrupts DNA replication and repair, with limited cardiotoxicity and antineoplastic range.Formula:C21H25N5O4Color and Shape:SolidMolecular weight:411.45Topoisomerase IIα-IN-2
CAS:Topoisomerase IIα-IN-2 (compound 5) is a DNA-binding ligands and a potent inhibitor of the topoisomerase TopoIIα.Formula:C22H20N4O5Color and Shape:SolidMolecular weight:420.42Anticancer agent 75
CAS:Anticancer agent 75: potent, selective, less toxic to kidneys than Doxorubicin by 35x, with antiplasmodial properties.Formula:C22H24N2OColor and Shape:SolidMolecular weight:332.44AVE-8134
CAS:AVE-8134 is an agonist of PPARα. For human and rodent PPARα receptor, the EC50 values are 100 and 3000 nM, respectively.Formula:C22H23NO5Purity:98%Color and Shape:SolidMolecular weight:381.42NHC-triphosphate
CAS:NHC-triphosphate is a weak alternative substrate for the viral polymerase and changes the mobility of the product in polyacrylamide electrophoresis gels.Formula:C9H16N3O15P3Purity:98%Color and Shape:SolidMolecular weight:499.16Topoisomerase I inhibitor 4
CAS:Topoisomerase I inhibitor 4 targets cancer cells like HepG2, A549, MCF-7, HeLa with low IC50, promising for research.Formula:C23H19FN4OColor and Shape:SolidMolecular weight:386.42SR 1903
CAS:SR 1903 modulates RORγ, LXR, PPARγ; shows anti-inflammatory and cholesterol-lowering effects in mice.Formula:C27H27F6N3OColor and Shape:SolidMolecular weight:523.512′-Deoxy-5-nitrocytidine
CAS:2′-Deoxy-5-nitrocytidine is a DNA Methyltransferase inhibitor that can be used for cancer research[1].Formula:C9H12N4O6Color and Shape:SolidMolecular weight:272.21ATR-IN-10
CAS:ATR-IN-10 is a potent and highly selective inhibitor of ATR kinase (IC50: 2.978 μM).Formula:C27H24N4OColor and Shape:SolidMolecular weight:420.51Pparδ agonist 2
CAS:Pparδ agonist 2 is an agonist of PPARδ.Formula:C20H18F3N3O3SPurity:98%Color and Shape:SolidMolecular weight:437.44WEHI-150
CAS:WEHI-150, a mitoxantrone analog, cross-links DNA, targets methylated CpG, halts transcription, and avoids guanine N-2 interaction.Formula:C22H30N6O4Color and Shape:SolidMolecular weight:442.51S26948
CAS:S26948 is a PPARγ agonist.Formula:C28H25NO7SPurity:98%Color and Shape:SolidMolecular weight:519.57Ro 47-3359
CAS:Ro 47-3359 is a topoisomerase II-targeted drugs with cytotoxic potential.Formula:C20H17FN4O3Color and Shape:SolidMolecular weight:380.37IID432
IID432, TopoII inhibitor against Trypanosoma cruzi (EC50=8 nM), achieves parasite clearance in Chagas disease models.Formula:C19H19N7OColor and Shape:SolidMolecular weight:361.4
