DNA Damage/DNA Repair
DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.
Subcategories of "DNA Damage/DNA Repair"
- ATM/ATR(72 products)
- DNA Alkylation(20 products)
- DNA Methyltransferase(460 products)
- DNA gyrase(6 products)
- DNA-PK(49 products)
- MTH1(1 products)
- Nucleoside Antimetabolite/Analog(1,418 products)
- Reverse Transcriptase(42 products)
- Sirtuin(90 products)
- Telomerase(34 products)
- Topoisomerase(126 products)
Show 3 more subcategories
Found 885 products of "DNA Damage/DNA Repair"
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IID432
IID432, TopoII inhibitor against Trypanosoma cruzi (EC50=8 nM), achieves parasite clearance in Chagas disease models.Formula:C19H19N7OColor and Shape:SolidMolecular weight:361.4XR-5000
CAS:XR-5000 is a DNA topoisomerase I and II inhibitor.Formula:C18H19N3OPurity:98%Color and Shape:SolidMolecular weight:293.366-Methyl-5-azacytidine
CAS:6-Methyl-5-azacytidine is a potent DNMT inhibitor.Formula:C9H14N4O5Purity:98%Color and Shape:SolidMolecular weight:258.23Ceralasertib formate
CAS:Ceralasertib: an oral ATR kinase inhibitor that blocks CHK1 phosphorylation, disrupts DNA repair, and triggers tumor cell apoptosis.Formula:C21H26N6O4SColor and Shape:SolidMolecular weight:458.54S26948
CAS:S26948 is a PPARγ agonist.Formula:C28H25NO7SPurity:98%Color and Shape:SolidMolecular weight:519.57DNA-PK-IN-5
CAS:DNA-PK-IN-5: potent DNA-PK inhibitor, reduces tumor repair, induces apoptosis, enhances radiotherapy, overcomes resistance.Formula:C21H22N8O2Color and Shape:SolidMolecular weight:418.45Alagebrium bromide
CAS:Alagebrium is a advanced glycation endproducts (AGE) cross-link breaker.Formula:C13H14BrNOSColor and Shape:SolidMolecular weight:312.23Porfiromycin
CAS:Porfiromycin, a mitomycin C derivative from Streptomyces, alkylates DNA and targets hypoxic cells.Formula:C16H20N4O5Color and Shape:SolidMolecular weight:348.35NK314
CAS:NK314, a benzo[c]phenanthridine, inhibits topoisomerase II causing DNA breaks within 1h, even without proteinase K digestion.Formula:C22H20ClNO4Color and Shape:SolidMolecular weight:397.85Carfloglitazar sodium
CAS:Carfloglitazar sodium is the salt form of Carfloglitazar, a peroxisome proliferator activating receptor (PPAR) agonist.Formula:C36H28FN2NaO4Color and Shape:SolidMolecular weight:594.61CAY10573
CAS:CAY10573, a potent PPARα/γ/δ agonist: IC50s - 113/50/223 nM, EC50s - 8/70/500 nM, outperforms rosiglitazone in PPARγ affinity.Formula:C33H31NO5Color and Shape:SolidMolecular weight:521.6AA-CW236
CAS:AA-CW236 is a covalent inhibitor of human O(6)-alkylguanine DNA methyltransferase (MGMT).Formula:C17H16ClF3N4O2Color and Shape:SolidMolecular weight:400.78PPARδ agonist 8
CAS:Pparδ agonist 8 is a potent agonist of Pparδ. Pparδ agonist 8 has potential for the study of nonalcoholic fatty liver disease (NAFLD).Formula:C25H29NO5Color and Shape:SolidMolecular weight:423.53,6-Diamino-9(10H)-acridone
CAS:3,6-Diamino-9(10H)-acridone is an inhibitor of topoisomerase [1].Formula:C13H11N3OColor and Shape:SolidMolecular weight:225.25DSO-5a
CAS:DSO-5a, a potent and selective orally active BB3 agonist, is a DMAKO-00 derivative that enhances ppar-γ activity via BB3 and stimulates ERK1/2 phosphorylation.Formula:C23H24N2O7Purity:98%Color and Shape:SolidMolecular weight:440.45DRF 2519
CAS:DRF 2519 is an activator of PPAR-alpha and PPAR-gamma.Formula:C20H18N2O5SColor and Shape:SolidMolecular weight:398.43Topoisomerase IIα-IN-1
CAS:Topoisomerase IIα-IN-1 (compound 2) is a DNA-binding ligands and a potent inhibitor of TopoIIα, a topoisomerase.Formula:C22H20N4O5Color and Shape:SolidMolecular weight:420.42Pparδ agonist 7
CAS:Pparδ agonist 7 is a potent agonist of Pparδ.Formula:C25H25NO5Color and Shape:SolidMolecular weight:419.47NSC-311068
CAS:NSC-311068: A selective TET1 inhibitor, reducing 5hmC and AML cell viability with high TET1.Formula:C10H6N4O4SColor and Shape:SolidMolecular weight:278.24LT175
CAS:LT175 is a dual PPARα/γ partial agonist, insulin sensitizer, orally active, with lower adipogeny (EC50: hPPARα 0.22μm, mPPARα 0.26μm, hPPARγ 0.48μm).Formula:C21H18O3Color and Shape:SolidMolecular weight:318.37
