
DNA Damage/DNA Repair
DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.
Subcategories of "DNA Damage/DNA Repair"
- ATM/ATR(72 products)
- DNA Alkylation(20 products)
- DNA Methyltransferase(460 products)
- DNA gyrase(6 products)
- DNA-PK(49 products)
- MTH1(1 products)
- Nucleoside Antimetabolite/Analog(1,418 products)
- Reverse Transcriptase(42 products)
- Sirtuin(90 products)
- Telomerase(34 products)
- Topoisomerase(126 products)
Show 3 more subcategories
Found 885 products of "DNA Damage/DNA Repair"
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BNS-22
CAS:BNS-22 is a DNA topoisomerase II (Topo II) inhibitor, induces mitotic abnormalities and exhibits antiproliferative activity against human cancer cells.Formula:C24H25NO5Purity:99.62%Color and Shape:SolidMolecular weight:407.46AM-3102
CAS:AM-3102: An OEA analog; boosts PPARα, delays eating, resists hydrolysis, mimics OEA potency, and weakly binds CB1/CB2.Formula:C21H41NO2Color and Shape:SolidMolecular weight:339.56Indotecan hydrochloride
CAS:Indotecan hydrochloride is a novel selective and potent topoisomerase I inhibitor with potential anticancer activitity.Formula:C26H27ClN2O7Color and Shape:SolidMolecular weight:514.96Huanglongmycin N
CAS:Huanglongmycin N acts as a DNA topoisomerase I inhibitor, demonstrating an EC50 value of 14 μM.Formula:C19H16O5Color and Shape:SolidMolecular weight:324.33DNA-PK-IN-4
CAS:DNA-PK-IN-4, an imidazolinone, targets DNA-PKcs to hinder tumor DNA repair and induce apoptosis, showing cancer research potential.Formula:C20H24N6O3Color and Shape:SolidMolecular weight:396.44Eicosatetraynoic acid
CAS:ETYA activates PPARα/γ at 10μM, inhibits cyclooxygenase (ID50=8μM) and lipoxygenase (ID50=4μM).Formula:C20H24O2Purity:98%Color and Shape:SolidMolecular weight:296.4PPARα-MO-1
CAS:PPARα-MO-1 is a potent modulator of PPARα.Formula:C27H37NO5Purity:98%Color and Shape:SolidMolecular weight:455.59T638
CAS:T638 is an inhibitor of topoisomerase II (TOP2). It specifically inhibits the activity of TOP2A with an IC50 of 0.7 uM and effectively suppresses the growth of cancer cells.Formula:C18H16N4OSColor and Shape:SolidMolecular weight:336.41G3335
CAS:H-Trp-Glu-OH: Selective, reversible PPARγ modulator; cell-permeable; Kd ~8μM; potential diabetes lead.Formula:C16H19N3O5Color and Shape:SolidMolecular weight:333.34SKLB-197
CAS:SKLB-197 targets ATR, inhibiting it at 0.013 μM, and is inactive on 402 other kinases, showing potent antitumor effects on ATM-deficient tumors.Formula:C25H24N6OColor and Shape:SolidMolecular weight:424.5A-1062
CAS:A-1062, a resolvase-binding inhibitor, inhibits resolvase binding to the res site.Formula:C18H10O6SPurity:98%Color and Shape:SolidMolecular weight:354.33Topoisomerase I inhibitor 6
CAS:Topoisomerase I inhibitor 6 traps DNA-Top1 complex, shows low non-cancer cell cytotoxicity, and has research value.Formula:C23H21N7OColor and Shape:SolidMolecular weight:411.46PPARγ agonist 5
CAS:PPARγ agonist 5 is a selective and potent PPARγ agonist that has shown research potential for cancer disease.Formula:C33H31N5OColor and Shape:SolidMolecular weight:513.63Exatecan mesylate dihydrate
CAS:Exatecan mesylate dihydrate (DX-8951), a DNA topoisomerase I inhibitor, exhibits an IC50 of 2.2 μM (0.975 μg/mL) and is utilized in cancer research [1] [2] [3].Formula:C25H30FN3O9SPurity:98%Color and Shape:SolidMolecular weight:567.58CP-67804
CAS:CP 67804 enhances topoisomerase II-mediated DNA cleaving.Formula:C18H13F2NO4Color and Shape:SolidMolecular weight:345.3Sabarubicin
CAS:Sabarubicin: a doxorubicin analogue with potent antitumor effects; superior in DNA fragmentation and topoisomerase II poisoning.Formula:C32H37NO13Color and Shape:SolidMolecular weight:643.64CAY10744
CAS:CAY10744, a topoisomerase II-α inhibitor (78.9% at 20 μM), blocks cancer cell proliferation with varying IC50s and induces apoptosis in T47D cells.Formula:C24H16ClNO2Color and Shape:SolidMolecular weight:385.8417(S)-HDHA
CAS:17(S)-HDHA: A DHA derivative in human blood/cells and mouse brain; leads to 17(S)-resolvins; inhibits IL-1β and leukocyte trafficking.Formula:C22H32O3Color and Shape:SolidMolecular weight:344.49DNMT3A-IN-1
CAS:DNMT3A-IN-1 is a potent, selective DNMT3A inhibitor with KI 9.16-18.85 μM (AdoMet) and 11.37-23.34 μM (poly dI-dC).Formula:C30H38N6O4Color and Shape:SolidMolecular weight:546.66NCI172112
CAS:NCI172112 is is used to develop antitumor agents effective against CNS tumors.Formula:C14H23Cl2N3O2Purity:98%Color and Shape:SolidMolecular weight:336.26
