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DNA Damage/DNA Repair

DNA Damage/DNA Repair

DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.

Subcategories of "DNA Damage/DNA Repair"

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Found 885 products of "DNA Damage/DNA Repair"

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  • BNS-22

    CAS:
    BNS-22 is a DNA topoisomerase II (Topo II) inhibitor, induces mitotic abnormalities and exhibits antiproliferative activity against human cancer cells.
    Formula:C24H25NO5
    Purity:99.62%
    Color and Shape:Solid
    Molecular weight:407.46

    Ref: TM-T62037

    1mg
    105.00€
    5mg
    250.00€
    10mg
    400.00€
    25mg
    707.00€
    50mg
    973.00€
    100mg
    1,314.00€
  • AM-3102

    CAS:
    AM-3102: An OEA analog; boosts PPARα, delays eating, resists hydrolysis, mimics OEA potency, and weakly binds CB1/CB2.
    Formula:C21H41NO2
    Color and Shape:Solid
    Molecular weight:339.56

    Ref: TM-T29938

    5mg
    148.00€
    10mg
    268.00€
    50mg
    1,108.00€
  • Indotecan hydrochloride

    CAS:
    Indotecan hydrochloride is a novel selective and potent topoisomerase I inhibitor with potential anticancer activitity.
    Formula:C26H27ClN2O7
    Color and Shape:Solid
    Molecular weight:514.96

    Ref: TM-T71185

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • Huanglongmycin N

    CAS:
    Huanglongmycin N acts as a DNA topoisomerase I inhibitor, demonstrating an EC50 value of 14 μM.
    Formula:C19H16O5
    Color and Shape:Solid
    Molecular weight:324.33

    Ref: TM-T72727

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • DNA-PK-IN-4

    CAS:
    DNA-PK-IN-4, an imidazolinone, targets DNA-PKcs to hinder tumor DNA repair and induce apoptosis, showing cancer research potential.
    Formula:C20H24N6O3
    Color and Shape:Solid
    Molecular weight:396.44

    Ref: TM-T61857

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • Eicosatetraynoic acid

    CAS:
    ETYA activates PPARα/γ at 10μM, inhibits cyclooxygenase (ID50=8μM) and lipoxygenase (ID50=4μM).
    Formula:C20H24O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:296.4

    Ref: TM-T11169

    5mg
    172.00€
    10mg
    314.00€
    25mg
    740.00€
    50mg
    1,288.00€
  • PPARα-MO-1

    CAS:
    PPARα-MO-1 is a potent modulator of PPARα.
    Formula:C27H37NO5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:455.59

    Ref: TM-T10505

    25mg
    1,586.00€
    50mg
    2,072.00€
    100mg
    2,660.00€
  • T638

    CAS:
    T638 is an inhibitor of topoisomerase II (TOP2). It specifically inhibits the activity of TOP2A with an IC50 of 0.7 uM and effectively suppresses the growth of cancer cells.
    Formula:C18H16N4OS
    Color and Shape:Solid
    Molecular weight:336.41

    Ref: TM-T88452

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • G3335

    CAS:
    H-Trp-Glu-OH: Selective, reversible PPARγ modulator; cell-permeable; Kd ~8μM; potential diabetes lead.
    Formula:C16H19N3O5
    Color and Shape:Solid
    Molecular weight:333.34

    Ref: TM-T21598

    10mg
    105.00€
    25mg
    215.00€
    50mg
    316.00€
    100mg
    600.00€
  • SKLB-197

    CAS:
    SKLB-197 targets ATR, inhibiting it at 0.013 μM, and is inactive on 402 other kinases, showing potent antitumor effects on ATM-deficient tumors.
    Formula:C25H24N6O
    Color and Shape:Solid
    Molecular weight:424.5

    Ref: TM-T62290

    25mg
    643.00€
    50mg
    837.00€
    100mg
    1,341.00€
  • A-1062

    CAS:
    A-1062, a resolvase-binding inhibitor, inhibits resolvase binding to the res site.
    Formula:C18H10O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:354.33

    Ref: TM-T26462

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • Topoisomerase I inhibitor 6

    CAS:
    Topoisomerase I inhibitor 6 traps DNA-Top1 complex, shows low non-cancer cell cytotoxicity, and has research value.
    Formula:C23H21N7O
    Color and Shape:Solid
    Molecular weight:411.46

    Ref: TM-T62094

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • PPARγ agonist 5

    CAS:
    PPARγ agonist 5 is a selective and potent PPARγ agonist that has shown research potential for cancer disease.
    Formula:C33H31N5O
    Color and Shape:Solid
    Molecular weight:513.63

    Ref: TM-T63561

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • Exatecan mesylate dihydrate

    CAS:
    Exatecan mesylate dihydrate (DX-8951), a DNA topoisomerase I inhibitor, exhibits an IC50 of 2.2 μM (0.975 μg/mL) and is utilized in cancer research [1] [2] [3].
    Formula:C25H30FN3O9S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:567.58

    Ref: TM-T78630

    5mg
    To inquire
    50mg
    To inquire
  • CP-67804

    CAS:
    CP 67804 enhances topoisomerase II-mediated DNA cleaving.
    Formula:C18H13F2NO4
    Color and Shape:Solid
    Molecular weight:345.3

    Ref: TM-T31028

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • Sabarubicin

    CAS:
    Sabarubicin: a doxorubicin analogue with potent antitumor effects; superior in DNA fragmentation and topoisomerase II poisoning.
    Formula:C32H37NO13
    Color and Shape:Solid
    Molecular weight:643.64

    Ref: TM-T69896

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • CAY10744

    CAS:
    CAY10744, a topoisomerase II-α inhibitor (78.9% at 20 μM), blocks cancer cell proliferation with varying IC50s and induces apoptosis in T47D cells.
    Formula:C24H16ClNO2
    Color and Shape:Solid
    Molecular weight:385.84

    Ref: TM-T36195

    1mg
    178.00€
    5mg
    760.00€
    10mg
    1,423.00€
  • 17(S)-HDHA

    CAS:
    17(S)-HDHA: A DHA derivative in human blood/cells and mouse brain; leads to 17(S)-resolvins; inhibits IL-1β and leukocyte trafficking.
    Formula:C22H32O3
    Color and Shape:Solid
    Molecular weight:344.49

    Ref: TM-T35947

    25µg
    227.00€
    50µg
    410.00€
    100µg
    755.00€
    250µg
    1,773.00€
  • DNMT3A-IN-1

    CAS:
    DNMT3A-IN-1 is a potent, selective DNMT3A inhibitor with KI 9.16-18.85 μM (AdoMet) and 11.37-23.34 μM (poly dI-dC).
    Formula:C30H38N6O4
    Color and Shape:Solid
    Molecular weight:546.66

    Ref: TM-T63859

    25mg
    2,178.00€
    50mg
    2,835.00€
  • NCI172112

    CAS:
    NCI172112 is is used to develop antitumor agents effective against CNS tumors.
    Formula:C14H23Cl2N3O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:336.26

    Ref: TM-T12195

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€