DNA Damage/DNA Repair
DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.
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Subcategories of "DNA Damage/DNA Repair"
ATM/ATR
DNA Alkylation
DNA Methyltransferase
DNA gyrase
DNA-PK
MTH1
Nucleoside Antimetabolite/Analog
Reverse Transcriptase
Sirtuin
Telomerase
Topoisomerase
Show 3 more subcategories
Products of "DNA Damage/DNA Repair"
Antitumor agent-104
CAS:2245272-16-4
Antitumor Agent-104 (Compound 9) serves as an antineoplastic by impeding DNA repair mechanisms in tumor …
Formula:
C31H33FN6O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
556.63
Ref: TM-T79265
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Bocodepsin hydrochloride
CAS:1834513-66-4
Bocodepsin hydrochloride (OKI-179) is a selective HDAC inhibitor with antitumor properties, efficacious via oral administration.
Formula:
C26H40ClN5O6S2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
618.21
Ref: TM-T79840
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
K-756
CAS:130017-40-2
K-756 is a direct and selective inhibitor of tankyrase (TNKS), which inhibits the ADP-ribosylation activity …
Formula:
C24H27N5O3
Purity:
99.68%
Color and Shape:
Solid
Molecular weight:
433.5
Ref: TM-T15639
| 2mg | 43.00 € | ||
| 5mg | 62.00 € | ||
| 10mg | 99.00 € | ||
| 25mg | 185.00 € | ||
| 50mg | 331.00 € | ||
| 100mg | 472.00 € | ||
| 200mg | 636.00 € | ||
| 1mL*10mM (DMSO) | 75.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
HDAC8-IN-4
CAS:1600528-05-9
HDAC8-IN-4 is a selective HDAC8 inhibitor, exhibiting inhibitory activity with IC50 values of 0.15 μM …
Formula:
C17H14N2O2S2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
342.44
Ref: TM-T79082
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
PARP7-IN-16
CAS:2435657-10-4
PARP7-IN-16 (compound 36) is a potent, selective, and orally active PARP-1/2/7 inhibitor, exhibiting IC50 values …
Formula:
C25H26FN4NaO4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
488.49
Ref: TM-T81541
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
WAY-354574
CAS:851873-40-0
WAY-354574 is an active compound that targets the deacetylase Sirtuin, utilized in research focused on …
Formula:
C20H23ClN2O3S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
406.93
Ref: TM-T80813
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Lartesertib
CAS:2495096-26-7
Lartesertib (ATM Inhibitor-5) is an inhibitor of the serine/threonine protein kinase ATM with potential anticancer …
Formula:
C23H21FN6O3
Purity:
99.9%
Color and Shape:
Solid
Molecular weight:
448.45
Ref: TM-T62684
| 1mg | 128.00 € | ||
| 2mg | 183.00 € | ||
| 5mg | 306.00 € | ||
| 10mg | 524.00 € | ||
| 25mg | 1,016.00 € | ||
| 50mg | 1,696.00 € | ||
| 100mg | 2,627.00 € | ||
| 1mL*10mM (DMSO) | 342.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
9-Chloromethyl-10-hydroxy-11-F-Camptothecin
CAS:2414594-22-0
9-Chloromethyl-10-hydroxy-11-F-Camptothecin, a novel derivative of camptothecin, functions as a DNA topoisomerase I (Topo I) inhibitor …
Formula:
C22H18ClFN2O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
428.84
Ref: TM-T79883
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
MDL-811
CAS:2275619-98-0
MDL-811, an allosteric activator of SIRT6, markedly enhances the deacetylation of histone H3 at lysine …
Formula:
C25H25BrCl2FN3O5S2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
681.42
Ref: TM-T81831
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Sirt1/2-IN-3
CAS:301313-42-8
Sirt1/2-IN-3 (compound PS9) serves as a dual inhibitor of SIRT1/2, exhibiting IC50 values of 1.4 …
Formula:
C17H14ClNO4S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
363.82
Ref: TM-T79564
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Tankyrase-IN-5
CAS:1460285-69-1
Tankyrase-IN-5 (Compound 30f), structurally related to MSC2504877, effectively inhibits tankyrase isoforms TNKS1 and TNKS2, with …
Formula:
C17H18N2O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
282.34
Ref: TM-T79026
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Lerzeparib
CAS:2459693-01-5
Lerzeparib is a PARP (ADP-ribose polymerase) inhibitor that exhibits antineoplastic activity [1].
Formula:
C21H20FN3O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
365.4
Ref: TM-T79853
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
PARP7-IN-15
CAS:2819998-97-3
PARP7-IN-15 (Compound 18) is a potent PARP7 inhibitor exhibiting an IC50 of 0.56 nM and …
Formula:
C23H24F6N6O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
562.46
Ref: TM-T81542
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Epigenetic factor-IN-1
CAS:2640673-56-7
Epigenetic factor-IN-1 (40569Z) is an epigenetic factor inhibitor that exhibits potent binding affinity for SIRT7.
Formula:
C32H34FN5O6S2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
667.77
Ref: TM-T82458
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
YM-08
CAS:812647-88-4
YM-08 (Compound 7a), a brain-penetrant SIRT2 inhibitor, exhibits an IC50 of 19.9 μM. Additionally, it …
Formula:
C19H17N3OS2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
367.49
Ref: TM-T80752
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
IACS-52825
CAS:2640376-72-1
IACS-52825 is a DLK inhibitor that reverses para-mechanical aberrant pain in a CIPN mouse model …
Formula:
C16H13F7N4O2
Purity:
99.78%
Color and Shape:
Solid
Molecular weight:
426.29
Ref: TM-T79303
| 1mg | 181.00 € | ||
| 5mg | 449.00 € | ||
| 10mg | 642.00 € | ||
| 25mg | 1,002.00 € | ||
| 50mg | 1,383.00 € | ||
| 100mg | 1,828.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
PARP1-IN-14
CAS:2098639-70-2
PARP1-IN-14 (compound 19k) is a potent PARP1 inhibitor demonstrating an inhibition concentration (IC50) of 0.6 …
Formula:
C28H24FN7O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
525.53
Ref: TM-T79593
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
NH2-methylpropanamide-Exatecan TFA
CAS:1817857-35-4
Exatecan TFA, a methylpropanamide-modified derivative of the common ADC cytotoxin Exatecan, serves as a DNA …
Formula:
C30H30F4N4O7
Purity:
98%
Color and Shape:
Solid
Molecular weight:
634.58
Ref: TM-T77889
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Sirt1/2-IN-2
CAS:670267-73-9
Sirt1/2-IN-2 (compound hsa55) serves as a dual inhibitor for SIRT1 with an IC50 of 1.8 …
Formula:
C18H14N4O3S2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
398.46
Ref: TM-T79563
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
7-Deaza-2′-deoxyguanosine 5′-triphosphate
CAS:101515-08-6
7-Deaza-2′-deoxyguanosine 5′-triphosphate (7-Deaza-2'-dGTP), a nucleotide analogue, functions as a telomerase inhibitor with an IC50 value …
Formula:
C11H17N4O13P3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
506.19
Ref: TM-T83248
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
