DNA Damage/DNA Repair
DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.
Read more
Subcategories of "DNA Damage/DNA Repair"
ATM/ATR
DNA Alkylation
DNA Methyltransferase
DNA gyrase
DNA-PK
MTH1
Nucleoside Antimetabolite/Analog
Reverse Transcriptase
Sirtuin
Telomerase
Topoisomerase
Show 3 more subcategories
Products of "DNA Damage/DNA Repair"
Trovafloxacin mesylate
CAS:147059-75-4
Trovafloxacin: broad-spectrum fluoroquinolone, blocks DNA gyrase/topoisomerase IV and PANX1 channel (IC50=4μM).
Formula:
C21H19F3N4O6S
Purity:
99.12%
Color and Shape:
Solid
Molecular weight:
512.46
Ref: TM-T13231L
| 1mg | 37.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 184.00 € | ||
| 50mg | 359.00 € | ||
| 100mg | 537.00 € | ||
| 1mL*10mM (DMSO) | 98.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
SIRT5 inhibitor 7
CAS:2951090-00-7
SIRT5 inhibitor 7 (compound 58), a selective and substrate-competitive SIRT5 inhibitor, exhibits anti-inflammatory properties by …
Formula:
C28H32ClN7O3S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
582.12
Ref: TM-T78803
| 25mg | 1,549.00 € | ||
| 50mg | 2,038.00 € | ||
| 100mg | 2,617.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
SIRT-IN-1
CAS:1431411-60-7
SIRT-IN-1 is a potent SIRT1/2/3 inhibitor(IC50s of 15, 10, 33 μM, respectively).
Formula:
C19H27N5O2S
Purity:
97.07%
Color and Shape:
Solid
Molecular weight:
389.52
Ref: TM-T12918
| 1mg | 51.00 € | ||
| 5mg | 112.00 € | ||
| 10mg | 181.00 € | ||
| 25mg | 307.00 € | ||
| 50mg | 434.00 € | ||
| 100mg | 616.00 € | ||
| 200mg | 811.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
MPI_5a
CAS:1259296-46-2
MPI_5a selectively inhibits HDAC6 (IC50=36 nM), slightly affects other HDACs, and blocks acyl-tubulin build-up (IC50=210 …
Formula:
C16H17N3O3
Purity:
99.16%
Color and Shape:
Solid
Molecular weight:
299.32
Ref: TM-T16129
| 1mg | 260.00 € | ||
| 2mg | 414.00 € | ||
| 5mg | 783.00 € | ||
| 10mg | 1,050.00 € | ||
| 25mg | 1,560.00 € | ||
| 50mg | 2,097.00 € | ||
| 100mg | 2,769.00 € | ||
| 1mL*10mM (DMSO) | 682.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
ATR-IN-24
CAS:2370889-43-1
ATR-IN-24 (Compound 1) is an ATR inhibitor with demonstrated anticancer activity [1].
Formula:
C23H26N6O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
418.49
Ref: TM-T79058
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
SIRT6-IN-3
CAS:3023471-40-8
SIRT6-IN-3 (compound 8a), a selective SIRT6 inhibitor (IC50 = 7.49 μM), impedes the proliferation of …
Formula:
C21H30Br3ClN6S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
673.73
Ref: TM-T79689
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
SRT3657
CAS:1383551-17-4
SRT3657 is a brain-permeable SIRT1 activator, has neuroprotective effect.
Formula:
C40H54N8O6S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
774.97
Ref: TM-T13001
| 25mg | 1,827.00 € | ||
| 50mg | 2,412.00 € | ||
| 100mg | 3,178.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
BChE/HDAC6-IN-1
CAS:2925457-27-6
BChE/HDAC6-IN-1 is a dual BChE/HDAC6 inhibitor that exhibits potent and selective inhibition with IC50 values …
Formula:
C34H43N5O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
601.74
Ref: TM-T78799
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
CPT-Se3
CAS:2968315-02-6
CPT-Se3, a camptothecin derivative, boosts anticancer activity, triggers apoptosis in Hep G2, and is cytotoxic …
Formula:
C24H20N2O6Se2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
590.35
Ref: TM-T73421
| 25mg | 1,549.00 € | ||
| 50mg | 2,038.00 € | ||
| 100mg | 2,617.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
ATR-IN-21
CAS:2905312-17-4
ATR-IN-21, also known as compound 60, is a potent inhibitor of ATR, exhibiting an IC50 …
Formula:
C23H27N7O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
417.51
Ref: TM-T79031
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
AZ31
CAS:2088113-98-6
AZ31 is an ATM inhibitor with potency, high selectivity, and oral activity.AZ31 inhibits ATM enzymes, …
Formula:
C24H28N4O3
Purity:
98.01%
Color and Shape:
Solid
Molecular weight:
420.5
Ref: TM-T19671
| 1mg | 52.00 € | ||
| 5mg | 102.00 € | ||
| 10mg | 165.00 € | ||
| 25mg | 267.00 € | ||
| 50mg | 400.00 € | ||
| 100mg | 579.00 € | ||
| 1mL*10mM (DMSO) | 123.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
ZL-2201
CAS:2865115-39-3
ZL-2201 is a potent inhibitor of DNA-PK, demonstrating an IC50 value of 1 nM.
Formula:
C20H25N9O5S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
503.54
Ref: TM-T78645
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
HDAC-IN-59
CAS:2944459-43-0
HDAC-IN-59 (compound 13a), a potent histone deacetylase (HDAC) inhibitor, enhances intracellular reactive oxygen species (ROS) …
Formula:
C20H25NO7
Purity:
98%
Color and Shape:
Solid
Molecular weight:
391.42
Ref: TM-T78766
| 5mg | 1,290.00 € | ||
| 50mg | 2,618.00 € | ||
| 100mg | 3,484.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Nesuparib
CAS:2055357-64-5
Nesuparib, a potent PARP/TNKS1 inhibitor, has antitumor properties and potential for treating various diseases.
Formula:
C23H24N6O
Purity:
99.71%
Color and Shape:
Solid
Molecular weight:
400.48
Ref: TM-T61932
| 1mg | 87.00 € | ||
| 5mg | 207.00 € | ||
| 10mg | 331.00 € | ||
| 25mg | 593.00 € | ||
| 50mg | 807.00 € | ||
| 100mg | 1,098.00 € | ||
| 1mL*10mM (DMSO) | 231.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Topoisomerase II inhibitor 15
CAS:451516-79-3
Topoisomerase II inhibitor 15 (compound 2g) serves as a potent apoptotic inducer, exhibiting heightened selectivity …
Formula:
C15H11Cl2N5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
332.19
Ref: TM-T79506
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Duocarmycin Analog
CAS:372954-15-9
Duocarmycin Analog is used as an DNA alkylator and ADC cytotoxin. Duocarmycin Analog is an …
Formula:
C34H31ClN4O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
611.09
Ref: TM-T19300
| 25mg | 1,967.00 € | ||
| 50mg | 2,598.00 € | ||
| 100mg | 3,458.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
E7016
CAS:902128-92-1
E7016 (GPI 21016) is an orally available PARP inhibitor. E7016 inhibits of DNA repair. E7016 …
Formula:
C20H19N3O3
Purity:
98.16%
Color and Shape:
Solid
Molecular weight:
349.38
Ref: TM-T61189
| 1mg | 127.00 € | ||
| 5mg | 305.00 € | ||
| 10mg | 461.00 € | ||
| 25mg | 738.00 € | ||
| 50mg | 1,012.00 € | ||
| 100mg | 1,447.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
ARN-21934
CAS:2230854-93-8
ARN-21934 inhibits human topoisomerase II α/β; IC50=2μM; stronger than Etoposide (IC50=120μM) in DNA relaxation.
Formula:
C21H24N6
Purity:
100%
Color and Shape:
Solid
Molecular weight:
360.46
Ref: TM-T36968
| 1mg | 60.00 € | ||
| 2mg | 87.00 € | ||
| 5mg | 130.00 € | ||
| 10mg | 205.00 € | ||
| 25mg | 360.00 € | ||
| 50mg | 491.00 € | ||
| 100mg | 677.00 € | ||
| 200mg | 911.00 € | ||
| 1mL*10mM (DMSO) | 145.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
JMJD3/HDAC-IN-1
CAS:2883046-06-6
Compound A5b, also known as JMJD3/HDAC-IN-1, is a dual inhibitor that targets both JMJD3 (Jumonji …
Formula:
C21H30N6O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
398.5
Ref: TM-T79713
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
HDAC/BET-IN-1
CAS:2757573-68-3
HDAC/BET-IN-1 inhibits HDAC1 (IC50: 0.163 μM), HDAC6 (IC50: 0.067 μM), BRD4 (Ki: 0.076 μM), and …
Formula:
C29H40N4O8S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
604.71
Ref: TM-T72872
| 25mg | 1,549.00 € | ||
| 50mg | 2,038.00 € | ||
| 100mg | 2,617.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
