DNA Damage/DNA Repair
DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.
Subcategories of "DNA Damage/DNA Repair"
- ATM/ATR(72 products)
- DNA Alkylation(20 products)
- DNA Methyltransferase(460 products)
- DNA gyrase(6 products)
- DNA-PK(49 products)
- MTH1(1 products)
- Nucleoside Antimetabolite/Analog(1,418 products)
- Reverse Transcriptase(42 products)
- Sirtuin(90 products)
- Telomerase(34 products)
- Topoisomerase(126 products)
Show 3 more subcategories
Found 885 products of "DNA Damage/DNA Repair"
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MD001
CAS:MD001 is a PPARα/γ agonist, binds at Kds 9.55/0.14 μM, boosts transcription, and regulates glucose, lipid levels in diabetic mice.Formula:C25H18O5Color and Shape:SolidMolecular weight:398.41DB-959 (salt)
CAS:DB-959, a PPAR agonist, is used potentially for the treatment of Alzheimer's disease.Formula:C25H27NNaO5Color and Shape:SolidMolecular weight:444.483PR-104
CAS:PR-104: hypoxia-activated DNA cross-linker, pre-prodrug for nitrogen mustard, converts to PR-104A in tumors.Formula:C14H20BrN4O12PSColor and Shape:SolidMolecular weight:579.27ZINC17167211
CAS:ZINC17167211 is a selective peroxisome proliferator-activated receptors-α agonist.Formula:C24H17FN2O6SPurity:98%Color and Shape:SolidMolecular weight:480.46Cas9-IN-2
CAS:Cas9-IN-2, an apo-Cas9 binder, inhibits Cas9 (IC50=246 μM), blocking Cas9:gRNA formation, regulating Cas9 function.Formula:C21H27N5O4S2Color and Shape:SolidMolecular weight:477.6Topoisomerase II inhibitor 8
CAS:Compound 22 is a potent topoisomerase II inhibitor (IC50=0.52μM), with strong anti-proliferative effects, arresting cells at G2/M.Formula:C14H8N4O3SColor and Shape:SolidMolecular weight:312.3TZD18
CAS:TZD18, a novel PPAR alpha/gamma dual agonist, inhibits cell growth and induces apoptosis in human glioblastoma T98G cells.Formula:C27H27NO5SColor and Shape:SolidMolecular weight:477.57CLX 0921
CAS:CLX 0921, a PPAR gamma agonist, is used potentially for the treatment of type 2 diabetes.Formula:C28H25NO7SPurity:98%Color and Shape:SolidMolecular weight:519.57PT-S58
CAS:PT-S58, a PPAR β/δ antagonist with 3x affinity than GSK0660, inhibits gene expression and blocks co-repressors like SMRT.Formula:C17H22N2O5S2Color and Shape:SolidMolecular weight:398.5Seladelpar Lysine dihydrate
CAS:Seladelpar lysine, a selective PPAR-δ agonist, is used for the therapy of Homozygous Familial Hypercholesterolemia (HoFH).Formula:C27H41F3N2O9SPurity:98%Color and Shape:SolidMolecular weight:626.68Eleutherin, (-)-
CAS:Eleutherin, (-)-, is a pyranonaphthoquinone derivative that inhibits DNA topoisomerase II.Formula:C16H16O4Color and Shape:SolidMolecular weight:272.3FTX-6746
CAS:FTX-6746 is an orally active and selective PPARG reverse inhibitor with anticancer activity. It can be used in research on urothelial carcinoma.Formula:C16H7ClF2N2OPurity:98.68%Color and Shape:SolidMolecular weight:316.69CP-67015
CAS:CP 67015 has an inhibitory effect on the function of topoisomerase, and is a direct mutagen in mammalian cells, which has effects on gene and chromosome levels.Formula:C17H12F2N2O3Color and Shape:SolidMolecular weight:330.29Dihydro-5-azacytidine acetate
CAS:Dihydro-5-azacytidine acetate (DHAC), a nucleoside analog, becomes integrated into DNA, thereby inhibiting DNA methylation, and exhibits antitumor activity [1Formula:C10H18N4O7Purity:98%Color and Shape:SolidMolecular weight:306.27TFMB-(S)-2-HG
CAS:TFMB-(S)-2-HG (TFMB S 2 HG) is a highly effective inhibitor of TET2, the 5'-methylcytosine hydroxylase.Formula:C13H11F3O4Purity:98.07%Color and Shape:SolidMolecular weight:288.22Ref: TM-T24871
2mg34.00€1mL*10mM (DMSO)49.00€5mg50.00€10mg79.00€25mg146.00€50mg227.00€100mg339.00€500mg713.00€ATR-IN-15
CAS:ATR-IN-15, an ATR kinase inhibitor, has an IC50 of 8 nM and also targets LoVo cells, DNA-PK, and PI3K with higher IC50 values.
Formula:C19H22N8OColor and Shape:SolidMolecular weight:378.43DC_517
CAS:DC_517 is an inhibitor of DNA methyltransferase 1 (DNMT1) ( IC50: 1.7 μM; Kd: 0.91 μM).Formula:C33H35N3O2Color and Shape:SolidMolecular weight:505.65Tetrahydrouridine
CAS:Tetrahydrouridine (NSC-112907; THU) is a multidrug resistance modulator.Formula:C9H16N2O6Purity:98%Color and Shape:SolidMolecular weight:248.23Daniquidone
CAS:Daniquidone (Batracylin) is a potent dual inhibitor of DNA topoisomerase I and DNA topoisomerase II with cytotoxic and antiproliferative activity for neoplasmsFormula:C15H11N3OPurity:98.39% - 99.52%Color and Shape:SolidMolecular weight:249.27Romazarit
CAS:Romazarit, a propionic acid derivative, is used as a PPARα agonist and acts as an antirheumatic drug.Formula:C15H16ClNO4Purity:98%Color and Shape:SolidMolecular weight:309.74
