DNA Damage/DNA Repair
DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.
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Subcategories of "DNA Damage/DNA Repair"
ATM/ATR
DNA Alkylation
DNA Methyltransferase
DNA gyrase
DNA-PK
MTH1
Nucleoside Antimetabolite/Analog
Reverse Transcriptase
Sirtuin
Telomerase
Topoisomerase
Show 3 more subcategories
Products of "DNA Damage/DNA Repair"
GSK-3484862
CAS:2170136-65-7
Gsk-3484862 is a non covalent inhibitor of DNA methyltransferase DNMT1 with anticancer activity.
Formula:
C19H19N5OS
Purity:
100% - 97.83%
Color and Shape:
Solid
Molecular weight:
365.45
Ref: TM-T11469
| 1mg | 50.00 € | ||
| 5mg | 119.00 € | ||
| 10mg | 187.00 € | ||
| 25mg | 335.00 € | ||
| 50mg | 512.00 € | ||
| 100mg | 730.00 € | ||
| 500mg | 1,473.00 € | ||
| 1mL*10mM (DMSO) | 215.00 € |
Estimated delivery in United States, on Friday 30 May 2025
SIRT-IN-1
CAS:1431411-60-7
SIRT-IN-1 is a potent SIRT1/2/3 inhibitor(IC50s of 15, 10, 33 μM, respectively).
Formula:
C19H27N5O2S
Purity:
97.07%
Color and Shape:
Solid
Molecular weight:
389.52
Ref: TM-T12918
| 1mg | 92.00 € | ||
| 5mg | 187.00 € | ||
| 10mg | 311.00 € | ||
| 25mg | 530.00 € | ||
| 50mg | 748.00 € | ||
| 100mg | 1,064.00 € | ||
| 500mg | 2,118.00 € |
Estimated delivery in United States, on Friday 30 May 2025
ARN-21934
CAS:2230854-93-8
ARN-21934 inhibits human topoisomerase II α/β; IC50=2μM; stronger than Etoposide (IC50=120μM) in DNA relaxation.
Formula:
C21H24N6
Purity:
100%
Color and Shape:
Solid
Molecular weight:
360.46
Ref: TM-T36968
| 1mg | 62.00 € | ||
| 2mg | 89.00 € | ||
| 5mg | 135.00 € | ||
| 10mg | 212.00 € | ||
| 25mg | 373.00 € | ||
| 50mg | 509.00 € | ||
| 100mg | 702.00 € | ||
| 200mg | 944.00 € | ||
| 1mL*10mM (DMSO) | 149.00 € |
Estimated delivery in United States, on Friday 30 May 2025
ZL-2201
CAS:2865115-39-3
ZL-2201 is a potent inhibitor of DNA-PK, demonstrating an IC50 value of 1 nM.
Formula:
C20H25N9O5S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
503.54
Ref: TM-T78645
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 30 May 2025
MPI_5a
CAS:1259296-46-2
MPI_5a selectively inhibits HDAC6 (IC50=36 nM), slightly affects other HDACs, and blocks acyl-tubulin build-up (IC50=210 …
Formula:
C16H17N3O3
Purity:
99.16%
Color and Shape:
Solid
Molecular weight:
299.32
Ref: TM-T16129
| 1mg | 264.00 € | ||
| 2mg | 423.00 € | ||
| 5mg | 797.00 € | ||
| 10mg | 1,074.00 € | ||
| 25mg | 1,586.00 € | ||
| 50mg | 2,147.00 € | ||
| 100mg | 2,822.00 € | ||
| 1mL*10mM (DMSO) | 685.00 € |
Estimated delivery in United States, on Friday 30 May 2025
Camonsertib
CAS:2417489-10-0
Camonsertib (RP-3500) is a novel, potent and selective ATR kinase inhibitor (ATRi) that exhibits potent …
Formula:
C21H26N6O3
Purity:
98.15% - 99.6%
Color and Shape:
Liquid
Molecular weight:
410.47
Ref: TM-T62083
| 1mg | 169.00 € | ||
| 5mg | 416.00 € | ||
| 10mg | 605.00 € | ||
| 25mg | 944.00 € | ||
| 50mg | 1,254.00 € | ||
| 100mg | 1,730.00 € | ||
| 1mL*10mM (DMSO) | 470.00 € |
Estimated delivery in United States, on Friday 30 May 2025
DNA-PK-IN-10
CAS:2919315-89-0
DNA-PK-IN-10 is a DNA-PK inhibitor utilized in the research of breast cancer and non-small cell …
Formula:
C25H28N6O2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
444.53
Ref: TM-T79165
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 30 May 2025
NT160
CAS:1418293-40-9
NT160 is a fluorinated radioactive compound, a potent class IIa histone deacetylase (HDAC) inhibitor, used …
Formula:
C21H21F3N4O2
Purity:
99.3%
Color and Shape:
Liquid
Molecular weight:
418.41
Ref: TM-T78709
| 1mg | 99.00 € | ||
| 5mg | 235.00 € | ||
| 10mg | 376.00 € | ||
| 25mg | 755.00 € | ||
| 50mg | 1,216.00 € | ||
| 100mg | 1,882.00 € | ||
| 1mL*10mM (DMSO) | 259.00 € |
Estimated delivery in United States, on Friday 30 May 2025
DY-46-2
CAS:1105110-83-5
DY-46-2 is a DNMT3A inhibitor (IC50: 0.39 ± 0.23 μM) with anticancer activity and is …
Formula:
C19H22N6O5S
Purity:
99.12% - 99.12%
Color and Shape:
Liquid
Molecular weight:
446.48
Ref: TM-T62643
| 1mg | 359.00 € | ||
| 25mg | 1,730.00 € | ||
| 50mg | 2,262.00 € | ||
| 100mg | 2,945.00 € |
Estimated delivery in United States, on Friday 30 May 2025
Bocodepsin
CAS:1834513-65-3
Bocodepsin (OKI-179) is a selective, orally active inhibitor of histone deacetylases (HDAC) with demonstrated antitumor …
Formula:
C26H39N5O6S2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
581.75
Ref: TM-T79839
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 30 May 2025
Topoisomerase inhibitor 2
CAS:2713986-17-3
Topoisomerase Inhibitor 2 (18C) is a broad-spectrum bacterial topoisomerase inhibitor effective against multidrug-resistant Gram-negative bacteria …
Formula:
C23H23N5O4
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
433.46
Ref: TM-T78717
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 30 May 2025
HDAC1/CDK7-IN-1
CAS:2987905-95-1
HDAC1/CDK7-IN-1 (compound 8e) serves as a dual inhibitor targeting both CDK7 and HDAC1, with IC50 …
Formula:
C33H32ClN7O4
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
626.11
Ref: TM-T82227
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 30 May 2025
ATR-IN-22
CAS:2905312-07-2
ATR-IN-22 (Compound 34), an orally active ATR inhibitor, exhibits potent anti-proliferative effects on MIAPaCa-2 cells …
Formula:
C25H31N7O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
445.56
Ref: TM-T79033
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 30 May 2025
ATR-IN-29
CAS:2761193-67-1
ATR-IN-29, a potent, orally active inhibitor of ATR kinase, exhibits an IC50 of 1 nM …
Formula:
C19H22N8O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
378.43
Ref: TM-T79121
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 30 May 2025
Antitumor agent-104
CAS:2245272-16-4
Antitumor Agent-104 (Compound 9) serves as an antineoplastic by impeding DNA repair mechanisms in tumor …
Formula:
C31H33FN6O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
556.63
Ref: TM-T79265
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 30 May 2025
K-756
CAS:130017-40-2
K-756 is a direct and selective inhibitor of tankyrase (TNKS), which inhibits the ADP-ribosylation activity …
Formula:
C24H27N5O3
Purity:
99.68%
Color and Shape:
Solid
Molecular weight:
433.5
Ref: TM-T15639
| 1mg | 52.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 169.00 € | ||
| 25mg | 316.00 € | ||
| 50mg | 567.00 € | ||
| 100mg | 810.00 € | ||
| 500mg | 1,644.00 € | ||
| 1mL*10mM (DMSO) | 114.00 € |
Estimated delivery in United States, on Friday 30 May 2025
NH2-methylpropanamide-Exatecan TFA
CAS:1817857-35-4
Exatecan TFA, a methylpropanamide-modified derivative of the common ADC cytotoxin Exatecan, serves as a DNA …
Formula:
C30H30F4N4O7
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
634.58
Ref: TM-T77889
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 30 May 2025
PARP7-IN-16
CAS:2435657-10-4
PARP7-IN-16 (compound 36) is a potent, selective, and orally active PARP-1/2/7 inhibitor, exhibiting IC50 values …
Formula:
C25H26FN4NaO4
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
488.49
Ref: TM-T81541
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 30 May 2025
SRT3657
CAS:1383551-17-4
SRT3657 is a brain-permeable SIRT1 activator, has neuroprotective effect.
Formula:
C40H54N8O6S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
774.97
Ref: TM-T13001
| 25mg | 1,872.00 € | ||
| 50mg | 2,452.00 € | ||
| 100mg | 3,230.00 € |
Estimated delivery in United States, on Friday 30 May 2025
TCS HDAC6 20b
CAS:956154-63-5
TCS HDAC6 20b (HDAC6-IN-7) is an HDAC6 inhibitor that blocks the growth of breast cancer …
Formula:
C26H44N2O4S
Purity:
99.28%
Color and Shape:
Solid
Molecular weight:
480.7
Ref: TM-T22159
| 1mg | 172.00 € | ||
| 5mg | 472.00 € | ||
| 10mg | 690.00 € | ||
| 25mg | 1,035.00 € |
Estimated delivery in United States, on Friday 30 May 2025
