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DNA Damage/DNA Repair

DNA Damage/DNA Repair

DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.

Subcategories of "DNA Damage/DNA Repair"

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Found 958 products of "DNA Damage/DNA Repair"

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  • WAY-354574

    CAS:
    <p>WAY-354574 is an active compound that targets the deacetylase Sirtuin, utilized in research focused on Huntington's disease (HD) [1].</p>
    Formula:C20H23ClN2O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:406.93
  • PARP7-IN-16

    CAS:
    <p>PARP7-IN-16 (compound 36) is a potent, selective, and orally active PARP-1/2/7 inhibitor, exhibiting IC50 values of 0.94, 0.87, and 0.21 nM , respectively.</p>
    Formula:C25H26FN4NaO4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:488.49
  • SDOX

    CAS:
    <p>SDOX, a prodrug, releases Doxorubicin selectively in high-GSH tumor cells, minimizing harm to healthy tissue.</p>
    Formula:C69H97NO20S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1324.63
  • Furegrelate sodium

    CAS:
    <p>Furegrelate sodium (U-63557A) is an orally active thromboxane synthase inhibitor with an IC50 of 15 nM in platelets.</p>
    Formula:C15H10NNaO3
    Purity:99.92%
    Color and Shape:Solid
    Molecular weight:275.23
  • Lexitropsin 1

    CAS:
    <p>Lexitropsin 1 is a new anticancer drug.</p>
    Formula:C15H19N7O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:377.42
  • 7-Deaza-2′-deoxyguanosine 5′-triphosphate

    CAS:
    <p>7-Deaza-2′-deoxyguanosine 5′-triphosphate (7-Deaza-2'-dGTP), a nucleotide analogue, functions as a telomerase inhibitor with an IC50 value of 11 μM [1].</p>
    Formula:C11H17N4O13P3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:506.19
  • (S)-Ceralasertib

    CAS:
    <p>(S)-Ceralasertib: Potent, selective ATR inhibitor with strong preclinical physicochemical and PK profiles.</p>
    Formula:C20H24N6O2S
    Color and Shape:Solid
    Molecular weight:412.51
  • ATR-IN-18

    CAS:
    <p>ATR-IN-18: oral ATR inhibitor, IC50 0.69 nM; halts LoVo cell growth, IC50 37.34 nM; anti-tumor.</p>
    Formula:C19H22F3N7O5S
    Color and Shape:Solid
    Molecular weight:517.48
  • Prostaglandin B3

    CAS:
    <p>Prostaglandin B3 (PGB3) is a secondary alcohol belonging to the prostaglandin B class, characterized by its relatively low affinity for human PPARγ, exhibiting a K_i value greater than 1 mM, in contrast to PGB1 and PGB2, which have K_i values of 26.28 ± 8.7 μM and 77 ± 37.7 μM, respectively [1].</p>
    Formula:C20H28O4
    Color and Shape:Solid
    Molecular weight:332.43
  • Ambamustine

    CAS:
    <p>Ambamustine (PTT 119): a tripeptide nitrogen mustard, DNA inhibitor/alkylator with antitumor properties, researched for various disorders.</p>
    Formula:C29H39Cl2FN4O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:629.61
  • ATR-IN-8

    CAS:
    <p>ATR-IN-8 is a potent inhibitor of ATR. ATR-IN-8 has shown potential research value in cancer diseases.</p>
    Formula:C20H22N6O2S
    Color and Shape:Solid
    Molecular weight:410.49
  • Oxamflatin

    CAS:
    <p>Oxamflatin (Metacept-3) is a selective histone deacetylase (HDAC) inhibitor with an alkyne group capable of azide-alkyne cycloaddition reactions (CuAAc).</p>
    Formula:C17H14N2O4S
    Purity:98.25%
    Color and Shape:Solid
    Molecular weight:342.37
  • KD-3010

    CAS:
    <p>KD-3010 (Kalypsys) is an orally active potent and selective PPARδ agonist for the study of liver injury.</p>
    Formula:C30H33F3N2O8S2
    Purity:99.61%
    Color and Shape:Solid
    Molecular weight:670.72
  • Nesuparib

    CAS:
    <p>Nesuparib, a potent PARP/TNKS1 inhibitor, has antitumor properties and potential for treating various diseases.</p>
    Formula:C23H24N6O
    Purity:99.71%
    Color and Shape:Solid
    Molecular weight:400.48
  • KPZ560

    CAS:
    <p>KPZ560, a potent HDAC 1 and HDAC 2 inhibitor, exhibits IC50 values of 12 nM and 68 nM, respectively.</p>
    Formula:C26H21N5O3S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:515.61
  • AZD4619

    CAS:
    <p>AZD4619 is a potent, selective and reversible orally bioavailable agonist of PPARα receptor.</p>
    Formula:C25H26O8S2
    Color and Shape:Solid
    Molecular weight:518.6
  • BM152054

    CAS:
    <p>BM152054 is a potent PPARγ ligand that induces glucose utilization in peripheral tissues by enhancing insulin action.</p>
    Formula:C22H18N2O4S3
    Purity:99.56%
    Color and Shape:Solid
    Molecular weight:470.58
  • Sipoglitazar

    CAS:
    <p>Sipoglitazar, a PPARγ agonist, is used potentially for the treatment of diabetes.</p>
    Formula:C25H25N3O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:463.55
  • Sirtuin modulator 1

    CAS:
    <p>Sirtuin modulator 1 (SRT3025 Hydrochloride) is a modulator of SIRT1 with EC1.5 of &lt; 1 μM.</p>
    Formula:C31H32ClN5O2S2
    Purity:99.63%
    Color and Shape:Solid
    Molecular weight:606.2
  • SIRT-IN-1

    CAS:
    <p>SIRT-IN-1 is a potent SIRT1/2/3 inhibitor(IC50s of 15, 10, 33 μM, respectively).</p>
    Formula:C19H27N5O2S
    Purity:99.29%
    Color and Shape:Solid
    Molecular weight:389.52