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DNA Damage/DNA Repair

DNA Damage/DNA Repair

DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.

Subcategories of "DNA Damage/DNA Repair"

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Found 958 products of "DNA Damage/DNA Repair"

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  • Ac-Exatecan
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    Ac-Exatecan

    CAS:
    <p>Ac-Exatecan is acetylation-modified Exatecan.Exatecan (DX-8951) is a DNA topoisomerase I (TOP1) inhibitor with an IC50 value of 2.2 μM and antitumor activity.</p>
    Formula:C26H24FN3O5
    Purity:97.09%
    Color and Shape:Solid
    Molecular weight:477.48

    Ref: TM-T77901

  • ZL-2201
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    ZL-2201

    CAS:
    <p>ZL-2201 is a potent inhibitor of DNA-PK, demonstrating an IC50 value of 1 nM.</p>
    Formula:C20H25N9O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:503.54

    Ref: TM-T78645

  • PARP7-IN-15
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    PARP7-IN-15

    CAS:
    <p>PARP7-IN-15 (Compound 18) is a potent PARP7 inhibitor exhibiting an IC50 of 0.56 nM and demonstrates antitumor activity [1].</p>
    Formula:C23H24F6N6O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:562.46

    Ref: TM-T81542

  • ATR-IN-6
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    ATR-IN-6

    CAS:
    <p>ATR-IN-6: potent ATR kinase inhibitor for cancer treatment, referenced in patent WO2021233376A1 as compound A22.</p>
    Formula:C28H28FN7O2
    Color and Shape:Solid
    Molecular weight:513.57

    Ref: TM-T63555

  • E7016
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    E7016

    CAS:
    <p>E7016 (GPI 21016) is an orally available PARP inhibitor. E7016 inhibits of DNA repair. E7016 can enhance tumor cell radiosensitivity in vitro and in vivo.</p>
    Formula:C20H19N3O3
    Purity:99.02%
    Color and Shape:Solid
    Molecular weight:349.38

    Ref: TM-T61189

  • IACS-52825
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    IACS-52825

    CAS:
    <p>IACS-52825 is a DLK inhibitor that reverses para-mechanical aberrant pain in a CIPN mouse model and can be used to study neurological disorders.</p>
    Formula:C16H13F7N4O2
    Purity:99.77%
    Color and Shape:Solid
    Molecular weight:426.29

    Ref: TM-T79303

  • CGS 15435
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    CGS 15435

    CAS:
    <p>CGS 15435: potent TxA2 synthase inhibitor, IC50=1 nM; less selective for PGI2 synthase, COX, and liposynthase.</p>
    Formula:C20H21ClN2O2
    Purity:99.86%
    Color and Shape:Solid
    Molecular weight:356.85

    Ref: TM-T10783

  • PARP-1-IN-4
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    PARP-1-IN-4

    CAS:
    <p>PARP-1-IN-4 is a potent PARP-1 inhibitor with potential see anti-tumor activity, and inhibition of PARP-1 may be used in cancer development.</p>
    Formula:C22H15Cl2N3O2
    Purity:99.82%
    Color and Shape:Solid
    Molecular weight:424.28

    Ref: TM-T78182

  • Lartesertib
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    Lartesertib

    CAS:
    <p>Lartesertib (ATM Inhibitor-5) is an inhibitor of the serine/threonine protein kinase ATM with potential anticancer activity and can be used to study lung cancer</p>
    Formula:C23H21FN6O3
    Purity:99.9%
    Color and Shape:Solid
    Molecular weight:448.45

    Ref: TM-T62684

  • AZ31
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    AZ31

    CAS:
    <p>AZ31 is an ATM inhibitor with potency, high selectivity, and oral activity.AZ31 inhibits ATM enzymes, intracellular ATM, with IC50 values of &lt;1.2 nM and 46 nM,</p>
    Formula:C24H28N4O3
    Purity:98.01%
    Color and Shape:Solid
    Molecular weight:420.5

    Ref: TM-T19671

  • Ragaglitazar
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    Ragaglitazar

    CAS:
    <p>Ragaglitazar(NNC-61-0029) is a potent dual activator of PPARγ and PPARα.Cost-effective and quality-assured.</p>
    Formula:C25H25NO5
    Purity:97.46% - 98.56%
    Color and Shape:Solid
    Molecular weight:419.47

    Ref: TM-T28501

  • Camonsertib
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    Camonsertib

    CAS:
    <p>Camonsertib (RP-3500) is a novel, potent and selective ATR kinase inhibitor (ATRi) that exhibits potent antitumor effects with an IC50: 1.00 nM in biochemical assays.Cost-effective and quality-assured.</p>
    Formula:C21H26N6O3
    Purity:99.6% - 99.93%
    Color and Shape:Solid
    Molecular weight:410.47

    Ref: TM-T62083

  • E-3030 free acid
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    E-3030 free acid

    CAS:
    <p>E-3030 free acid, a PPAR agonist, lowers blood glucose, triglycerides, and insulin; boosts adiponectin; reduces apo C-III; and raises lipoprotein lipase.</p>
    Formula:C22H23ClFNO5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:435.87

    Ref: TM-T27228

  • ATM Inhibitor-1
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    ATM Inhibitor-1

    CAS:
    <p>ATM Inhibitor-1 is a highly potent, selective and orally active ATM inhibito (IC50: 0.7 nM) anti-tumor activity.</p>
    Formula:C27H36N6O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:492.61

    Ref: TM-T10396

  • CymitQuimica logo
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    PPARγ agonist 1

    <p>PPARγ agonist 1 is a potent agonist of PPARγ that efficiently activates hPPARγ without causing full agonism, thereby avoiding adverse effects.</p>
    Formula:C34H39NO3
    Color and Shape:Solid
    Molecular weight:509.68

    Ref: TM-T63514

  • TP3011
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    TP3011

    CAS:
    <p>TP3011 is a potent topoisomerase I inhibitor equipotent as SN38 and is an active metabolite of CH-0793076.</p>
    Formula:C26H26N4O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:474.51

    Ref: TM-T13191

  • G-631
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    G-631

    CAS:
    <p>G-631 acts as a selective tankyrase inhibitor, effectively hindering tankyrase auto-PARsylation (poly ADP ribosylation) at an IC 50 of 7 nM and suppressing the Wnt signaling pathway. This compound also demonstrates favorable pharmacokinetic properties in mice.</p>
    Formula:C19H22F2N6O3
    Color and Shape:Solid
    Molecular weight:420.41

    Ref: TM-T200085

  • (Rac)-RG108
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    (Rac)-RG108

    CAS:
    <p>(Rac)-RG108 (NSC401077) is an inhibitor of DNMT1, effectively blocking DNA methyltransferases.</p>
    Formula:C19H14N2O4
    Color and Shape:Solid
    Molecular weight:334.326

    Ref: TM-T206761

  • TMU 35435
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    TMU 35435

    CAS:
    <p>TMU 35435 is an inhibitor of histone deacetylases (HDAC). It enhances radiosensitivity by inducing the accumulation of misfolded proteins and autophagy (autophagy) in TNBC, and inhibits the NHEJ pathway through ubiquitination of the catalytic subunit of DNA-dependent protein kinase (DNA-PKcs).</p>
    Formula:C22H25N3O3
    Color and Shape:Solid
    Molecular weight:379.45

    Ref: TM-T200171

  • Antibacterial agent 236
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    Antibacterial agent 236

    CAS:
    <p>Anti bacterial agent 236 (Compound 4l), an orally effective inhibitor of DNA gyrase and topoisomerase IV (with IC50 values of 3.2 and 300 nM in Staphylococcus aureus, respectively), exhibits broad-spectrum antibacterial activity. It also demonstrates favorable pharmacokinetic properties in mice.</p>
    Formula:C26H27N5O2S
    Color and Shape:Solid
    Molecular weight:473.59

    Ref: TM-T200041