DNA Damage/DNA Repair
DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.
Subcategories of "DNA Damage/DNA Repair"
- ATM/ATR(72 products)
- DNA Alkylation(13 products)
- DNA Methyltransferase(455 products)
- DNA gyrase(11 products)
- DNA-PK(48 products)
- MTH1(1 products)
- Nucleoside Antimetabolite/Analog(1,421 products)
- Reverse Transcriptase(42 products)
- Sirtuin(88 products)
- Telomerase(33 products)
- Topoisomerase(140 products)
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Found 1032 products of "DNA Damage/DNA Repair"
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Ketopioglitazone
CAS:Ketopioglitazone is an active metabolite of pioglitazone.Formula:C19H18N2O4SColor and Shape:SolidMolecular weight:370.42DNA gyrase/Topo IV-IN-1
DNA gyrase/Topo IV-IN-1 (Compound 27) is an inhibitor of DNA gyrase and topoisomerase IV with antibacterial properties. It exhibits IC50 values of 11 and 17 nM against the DNA gyrase of Escherichia coli and methicillin-resistant Staphylococcus aureus, respectively, and IC50 values of 83 and 21 nM against topoisomerase IV of the same organisms. DNA gyrase/Topo IV-IN-1 is applicable in anti-infective research.Formula:C44H59NO8Color and Shape:SolidMolecular weight:729.941Tafluposide
CAS:Tafluposide is a DNA topoisomerase inhibitor with anti-tumor activity.Formula:C45H35F10O20PColor and Shape:SolidMolecular weight:1116.713Becatecarin
CAS:Becatecarin, water-soluble and anti-cancer, inhibits topoisomerases I/II and induces DNA cleavage and apoptosis; has myelosuppressive effects; ABCG2 substrate.Formula:C33H34Cl2N4O7Color and Shape:SolidMolecular weight:669.56Wistin
CAS:Wistin, isolated from Caragana sinica roots, is a PPARα and PPARγ agonist [1] [2] .Formula:C23H24O10Color and Shape:SolidMolecular weight:460.43(±)9-HEPE
CAS:<p>(±)9-HEPE is produced by non-enzymatic oxidation of EPA.</p>Formula:C20H30O3Color and Shape:SolidMolecular weight:318.457Macrocalin B
CAS:Macrocalin B is a diterpenoid against tumor cell proliferation and telomerase activity.Formula:C20H26O6Color and Shape:SolidMolecular weight:362.42Et-29
CAS:<p>Et-29 is a selective inhibitor of SIRT5 inhibitor with a Ki of 40 nM.</p>Formula:C34H46N6O6SPurity:99.52%Color and Shape:SolidMolecular weight:666.83GW 1929 hydrochloride
CAS:Oral PPARγ agonist with pEC50 of 8.05; low affinity for PPARα, PPARδ. Reduces blood glucose, fatty acids, triglycerides in vivo.Formula:C30H30ClN3O4Color and Shape:SolidMolecular weight:532.04CUDA disodium
CUDA disodium is an effective, soluble epoxide hydrolase (sEH) inhibitor, with IC50 values of 11.1 nM for murine sEH and 112 nM for human sEH. It selectively enhances the activity of peroxisome proliferator-activated receptor PPARalpha. CUDA disodium may be valuable for cardiovascular disease research.Color and Shape:Odour SolidMonascin
CAS:Monascin: azaphilonoid in red-mold rice; anti-tumor and anti-inflammatory.Formula:C21H26O5Purity:98%Color and Shape:SolidMolecular weight:358.43Gemfibrozil 1-O-β-glucuronide
CAS:Gemfibrozil 1-O-β-Glucuronide, a metabolite of Gemfibrozil , is a potent and competitive P450 (CYP) isoform CYP2C8 inhibitor with an IC50 of 4.07 μM.Formula:C21H30O9Purity:98%Color and Shape:SolidMolecular weight:426.46Antitumor agent-28
CAS:Antitumor agent-28 inhibits ATM kinase, blocking ATM disease progression and showing anti-cancer effects.Formula:C25H32N6O4SColor and Shape:SolidMolecular weight:512.63PNU-142586
CAS:PNU-142586 is a bio-active chemical.Formula:C16H20FN3O6Color and Shape:SolidMolecular weight:369.34Multi-target kinase inhibitor 4
<p>Multi-target kinase inhibitor 4 (Compound 2) is a PI3K/DNA-PK inhibitor and a potent chemosensitizer that enhances the number of DNA double-strand breaks induced by Doxorubicin. It serves as an effective multidrug resistance (MDR) inhibitor, demonstrating inhibitory activity against P-glycoprotein (P-gp) mediated drug efflux. Multi-target kinase inhibitor 4 can be encapsulated in PEG-coated lipid nanoparticles.</p>Color and Shape:Odour SolidColibactin 742
CAS:Colibactin 742, a stable derivative of colibactin, efficiently induces DNA interstrand cross-links, activates the Fanconi Anemia DNA repair pathway, and leadsFormula:C37H42N8O5S2Color and Shape:SolidMolecular weight:742.91Hippeastrine
CAS:<p>Hippeastrine is an alkaloid that inhibits Top I dose-dependently with a 7.25 μg/mL IC50 and has anticancer properties.</p>Formula:C17H17NO5Color and Shape:SolidMolecular weight:315.32HDAC-IN-52
CAS:HDAC-IN-52: Pyridine-based inhibitor for HDAC1/2/3/10 with IC50s 0.189-0.446 μM, used in cancer studies.Formula:C24H20N4O2Purity:99.47%Color and Shape:SolidMolecular weight:396.44Ref: TM-T67878
1mg81.00€5mg162.00€10mg234.00€25mg356.00€50mg487.00€100mg658.00€200mg884.00€1mL*10mM (DMSO)178.00€15-deoxy-Δ-12,14-Prostaglandin J2
CAS:15-deoxy-Δ-12,14-Prostaglandin J2 is a PPARγ agonist.Formula:C20H28O3Purity:98%Color and Shape:Neat OilMolecular weight:316.43CP 84364
CAS:CP 84364 is a metabolite of CP-80794.Formula:C14H18N2O4Color and Shape:SolidMolecular weight:278.30
