DNA Damage/DNA Repair
DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.
Subcategories of "DNA Damage/DNA Repair"
- ATM/ATR(72 products)
- DNA Alkylation(17 products)
- DNA Methyltransferase(459 products)
- DNA gyrase(6 products)
- DNA-PK(49 products)
- MTH1(1 products)
- Nucleoside Antimetabolite/Analog(1,422 products)
- Reverse Transcriptase(42 products)
- Sirtuin(86 products)
- Telomerase(33 products)
- Topoisomerase(132 products)
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Found 948 products of "DNA Damage/DNA Repair"
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DNA Damage & Repair Compound Library
A unique collection of xnum DNA Damage & Repair related compounds for high throughput screening (HTS) and high content screening (HCS);
Color and Shape:Odour SolidWistin
CAS:Wistin, isolated from Caragana sinica roots, is a PPARα and PPARγ agonist [1] [2] .Formula:C23H24O10Color and Shape:SolidMolecular weight:460.4317-oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-Docosahexaenoic Acid
CAS:Aspirin-enhanced COX-2 metabolite of DHA, activates Nrf2 and PPARγ, inhibits inflammation, with EC50 ~200 nM, effective at 5-25 μM.Formula:C22H30O3Color and Shape:SolidMolecular weight:342.479Tibesaikosaponin V
CAS:TKV, a triterpene diglycoside from Bupleurum chinense, curbs lipid build-up and fat content in adipocytes without harm and hinders fat cell differentiation.Formula:C42H68O15Color and Shape:SolidMolecular weight:812.98NHC-diphosphate triammonium
NHC-triphosphate triammonium is a phosphorylated metabolite of NHC, incorporated into HCV RNA by viral polymerase.Color and Shape:Solid15-LOX-IN-2
15-LOX-IN-2 (Compound 2a) is an orally active inhibitor of COX-2/15-LOX and a partial agonist of PPARγ. It exhibits anti-inflammatory activity by inhibiting levels of 20-HETE, IL-1β, and TNF-α in LPS-treated RAW 264.7 cells. Additionally, it significantly enhances glucose uptake without the presence of insulin and is applicable in metabolic disease research.Color and Shape:Odour SolidDB1255 2TFA
DB1255 2TFA is an ERG/DNA binding inhibitor with an unusual and potent monomer binding pattern at the minor groove site for the study of genetic disorders.Formula:C26H20F6N4O4S2Purity:98.32%Color and Shape:SolidMolecular weight:630.58CL2-MMT-SN38
CAS:CL2-MMT-SN38 is a derivative of SN-38, which is a potent anticancer agent and the active metabolite of Irinotecan (CPT-11), a Topoisomerase I inhibitor.Formula:C102H122N12O24Color and Shape:SolidMolecular weight:1900.158GSK3735967
CAS:GSK3735967: DNMT1 inhibitor, IC50 40 nM, dicyanopyridine core, binds hemimethylated CpG, interacts with H4K20me3.Formula:C25H31N7OSColor and Shape:SolidMolecular weight:477.62Methylation Compound Library
xnum methylation-related compounds that can be used for high-throughput and high-content screening.Color and Shape:Odour SolidRef: TM-L3510
1mgTo inquire30μL*10mM (DMSO)To inquire50μL*10mM (DMSO)To inquire100μL*10mM (DMSO)To inquire250μL*10mM (DMSO)To inquire(±)4(5)-DiHDPA lactone
CAS:(±)5(6)-DiHET lactone is a 1,5 cyclic ester derived from (±)5(6)-DiHET , which, in turn, is a potential derivative of epoxidation of arachidonic acid at the α-5Formula:C22H32O3Color and Shape:SolidMolecular weight:344.495Topoisomerase IIα-IN-9
CAS:Compound EN300-20599, with CAS No. 16346-97-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound EN300-20599 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C14H14O4SColor and Shape:SolidMolecular weight:278.32Stearolic acid
CAS:Stearolic acid is a useful organic compound for research related to life sciences. The catalog number is T124753 and the CAS number is 506-24-1.Formula:C18H32O2Color and Shape:SolidMolecular weight:280.452PPARγ agonist 16
CAS:PPARγ agonist16 (Compound 4G) is a PPARγ agonist that competitively binds to the ligand-binding domain (LBD) of PPARγ with an IC50 of 1790 nM. It reduces ear swelling in mouse models and exhibits antihyperglycemic activity in mice with Streptozotocin-induced diabetes.Formula:C19H14BrNO4SColor and Shape:SolidMolecular weight:432.29Diflomotecan
CAS:Diflomotecan (BN 80915) is a strong oral topoisomerase I inhibitor with high plasma stability and significant preclinical anti-cancer efficacy.Formula:C21H16F2N2O4Color and Shape:SolidMolecular weight:398.36NHC-diphosphate
CAS:NHC-diphosphate, a phosphorylated β-d-N4-Hydroxycytidine metabolite, is a potent antiviral against VEEV, CHIKV, and HCV.Formula:C9H15N3O12P2Color and Shape:SolidMolecular weight:419.18CH-0793076
CAS:CH-0793076: hexacyclic camptothecin, TP300 metabolite, targets BCRP, inhibits DNA topo I (IC50: 2.3 μM).
Formula:C26H26N4O4Purity:98%Color and Shape:SolidMolecular weight:458.51GJ071 oxalate
CAS:GJ071 oxalate is a Nonsense suppressor that induces readthrough by inserting amino acids at premature termination codons.Formula:C20H29N3O7SPurity:99.97%Color and Shape:SolidMolecular weight:455.53Ref: TM-T31932
1mg73.00€5mg149.00€10mg213.00€25mg319.00€50mg450.00€100mg605.00€200mg802.00€1mL*10mM (DMSO)166.00€HDAC6-IN-50
HDAC6-IN-50 (Compound 4) is an effective inhibitor of HDAC6 with an IC50 value of 35 nM. It is utilized in the study of Parkinson's disease (PD) and Alzheimer's disease (AD).
Color and Shape:Odour SolidDST Crosslinker
CAS:DST is a cleavable, bifunctional crosslinker; it doesn't disrupt protein disulfides, breaks with oxidizers.Formula:C12H12N2O10Color and Shape:SolidMolecular weight:344.232
