DNA Damage/DNA Repair
DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.
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Subcategories of "DNA Damage/DNA Repair"
ATM/ATR
DNA Alkylation
DNA Methyltransferase
DNA gyrase
DNA-PK
MTH1
Nucleoside Antimetabolite/Analog
Reverse Transcriptase
Sirtuin
Telomerase
Topoisomerase
Show 3 more subcategories
Products of "DNA Damage/DNA Repair"
YCH1899
YCH1899, an orally active PARP inhibitor, demonstrates potent inhibition of PARP1/2 with an IC50 of …
Formula:
C25H18BrFN6O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
549.35
Ref: TM-T79667
| 1mg | 121.00 € | ||
| 5mg | 553.00 € | ||
| 10mg | 1,044.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
DRF-1042 HCl
DRF-1042 HCl is an orally active camptothecin analog with antitumor activity, inhibits DNA topoisomerase I, …
Formula:
C22H21ClN2O6
Purity:
99.212%
Color and Shape:
Liquid
Molecular weight:
444.87
Ref: TM-T15168L
| 1mg | 200.00 € | ||
| 5mg | 494.00 € | ||
| 10mg | 693.00 € | ||
| 25mg | 1,082.00 € | ||
| 50mg | 1,493.00 € | ||
| 100mg | 1,911.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PARP-1/2-IN-2
PARP-1/2-IN-2-IN-1 (Compound 12e) effectively inhibits PARP1/2 and CDK12 with IC 50 values of 34 nM, …
Formula:
C25H23IN8O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
610.41
Ref: TM-T78787
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
(rac)-Exatecan Intermediate 1
CAS:102978-40-5
(rac)-Exatecan Intermediate 1 is a camptothecin derivative, a potential topoisomerase I inhibitor, used in tumor …
Formula:
C13H13NO5
Color and Shape:
Liquid
Molecular weight:
263.25
Ref: TM-T88858
| 5mg | 35.00 € | ||
| 10mg | 51.00 € | ||
| 25mg | 79.00 € | ||
| 50mg | 112.00 € | ||
| 100mg | 175.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
HDAC6-IN-18
HDAC6-IN-18 (Compound 4), an irreversible and selective HDAC6 isoform inhibitor, exhibits potent anti-multiple myeloma effects.
Formula:
C16H13N3O7S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
391.36
Ref: TM-T79523
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
5-Hydroxymethyl-2'-deoxycytidine
CAS:7226-77-9
5-Hydroxymethyl-2'-deoxycytidine is an oxidized derivative of 5-methyl-2'-deoxycytidine (5-mdC) in DNA, causing DNA damage reactions, chromosomal …
Formula:
C10H15N3O5
Purity:
99.8%
Color and Shape:
Liquid
Molecular weight:
257.24
Ref: TM-T40834
| 1mg | 40.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 199.00 € | ||
| 50mg | 316.00 € | ||
| 100mg | 477.00 € | ||
| 500mg | 1,012.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
HDAC6-IN-17
HDAC6-IN-17 (compound 5b) is a potent inhibitor of HDAC6, exhibiting IC50 values of 150 nM …
Formula:
C22H17N3O3S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
403.45
Ref: TM-T78769
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
J27644
J27644 is a potent HDAC (histone deacetylase) inhibitor that mitigates TGF-β (transforming growth factor beta)-induced …
Formula:
C16H12ClN3O4
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
345.74
Ref: TM-T79543
| 1mg | 603.00 € | ||
| 5mg | 2,409.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PARP/HDAC-IN-1
PARP/HDAC-IN-1 is a PARP and HDAC inhibitor that inhibits PARP1, PARP2, and HDAC1, and may …
Formula:
C36H32F2N6O3
Purity:
95%
Color and Shape:
Liquid
Molecular weight:
634.67
Ref: TM-T85321
| 1mg | 181.00 € | ||
| 5mg | 449.00 € | ||
| 10mg | 642.00 € | ||
| 25mg | 1,002.00 € | ||
| 50mg | 1,383.00 € | ||
| 100mg | 1,828.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
CRA-026440 hydrochloride
CAS:847459-98-7
CRA-026440 hydrochloride is a potent and broad-spectrum HDAC inhibitor.
Formula:
C23H25ClN4O4
Purity:
99.78%
Color and Shape:
Soild
Molecular weight:
456.92
Ref: TM-T10883L
| 1mg | 114.00 € | ||
| 5mg | 271.00 € | ||
| 10mg | 427.00 € | ||
| 25mg | 725.00 € | ||
| 50mg | 1,144.00 € | ||
| 100mg | 1,548.00 € | ||
| 1mL*10mM (DMSO) | 45.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Ref: TM-T81393
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
3,7,4'-Trihydroxyflavone
CAS:2034-65-3
3,7,4'-Trihydroxyflavone(5-Deoxykampferol) is a DNA-breaking flavonoid isolated from rosewood heartwood. It inhibits osteoclast differentiation, actin ring …
Formula:
C15H10O5
Purity:
99.16%
Color and Shape:
Solid
Molecular weight:
270.24
Ref: TM-TN2143
| 1mg | 91.00 € | ||
| 5mg | 167.00 € | ||
| 10mg | 248.00 € | ||
| 25mg | 498.00 € | ||
| 50mg | 707.00 € | ||
| 100mg | 956.00 € | ||
| 500mg | 1,912.00 € | ||
| 1mL*10mM (DMSO) | 238.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PARP-1-IN-13
PARP-1-IN-13 (Compound 19c) is a potent PARP-1 inhibitor with an IC50 of 26 nM, hindering …
Formula:
C20H17N5O2S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
391.45
Ref: TM-T79330
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
GK444
GK444 (Compound 15a), a selective HDAC1/2 inhibitor with IC50 values of 100 nM and 92 …
Purity:
98%
Ref: TM-T82314
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
HSP70/SIRT2-IN-1
HSP70/SIRT2-IN-1 (Compound 2a) serves as a dual inhibitor targeting both SIRT2 and HSP70, exhibiting an …
Purity:
98%
Ref: TM-T82168
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Topoisomerase II inhibitor 13
CAS:451515-89-2
WAY-323966 suppresses Topo II, strongly halts HL-60/MX2 cancer cell growth, resists Topo II toxicity.
Formula:
C22H23N9
Purity:
98.4%
Color and Shape:
Soild
Molecular weight:
413.48
Ref: TM-T67899
| 2mg | 36.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 84.00 € | ||
| 25mg | 127.00 € | ||
| 50mg | 184.00 € | ||
| 100mg | 274.00 € | ||
| 200mg | 389.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
HDAC6-IN-16
HDAC6-IN-16 (compound 5c), a quinazolin-4(3H)-one-based inhibitor of histone deacetylase 6 (HDAC6), demonstrates an anticancer effect …
Formula:
C23H19N3O3S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
417.48
Ref: TM-T78768
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Euchrestaflavanone B
CAS:87402-91-3
Euchrestaflavanone B has antibacterial effects on Gram-positive bacteria and may inhibit cancer by targeting protein …
Formula:
C25H28O6
Purity:
98%
Color and Shape:
Solid
Molecular weight:
424.49
Ref: TM-TN4028
| 5mg | 1,914.00 € | ||
| 1mL*10mM (DMSO) | 2,292.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PARP1-IN-17
PARP1-IN-17 is an inhibitor that targets PARP-1 (IC50=19.24 nM ) with a slightly reduced affinity …
Purity:
98%
Ref: TM-T81543
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
SGC-UBD253
SGC-UBD253 is a potent antagonist of the HDAC6-UBD interaction and may be utilized in cancer …
Formula:
C21H20ClN3O5
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
429.85
Ref: TM-T79542
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
