DNA Damage/DNA Repair
DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.
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Subcategories of "DNA Damage/DNA Repair"
ATM/ATR
DNA Alkylation
DNA Methyltransferase
DNA gyrase
DNA-PK
MTH1
Nucleoside Antimetabolite/Analog
Reverse Transcriptase
Sirtuin
Telomerase
Topoisomerase
Show 3 more subcategories
Products of "DNA Damage/DNA Repair"
Nifurpirinol
CAS:13411-16-0
Nifurpirinol (P-7138) is an antimicrobial compound that is acutely toxic to milkfish species.
Formula:
C12H10N2O4
Color and Shape:
Solid
Molecular weight:
246.22
Ref: TM-T74065
| 1mg | 55.00 € | ||
| 5mg | 116.00 € | ||
| 10mg | 181.00 € | ||
| 25mg | 349.00 € | ||
| 50mg | 519.00 € |
Estimated delivery in United States, on Wednesday 6 Nov 2024
SCR7
CAS:1533426-72-0
SCR7, a specific DNA Ligase IV inhibitor, blocks nonhomologous end-joining (NHEJ).
Formula:
C18H14N4OS
Purity:
98%
Color and Shape:
Solid
Molecular weight:
334.4
Ref: TM-T3340
| 1mg | 86.00 € | ||
| 5mg | 259.00 € | ||
| 10mg | 437.00 € | ||
| 25mg | 814.00 € |
Estimated delivery in United States, on Wednesday 6 Nov 2024
Doxorubicin
CAS:23214-92-8
Doxorubicin (Adriamycin) is a Topoisomerase II (Top2) inhibitor with antineoplastic activity.
Formula:
C27H29NO11
Purity:
98%
Color and Shape:
Red Crystalline Solid Solid
Molecular weight:
543.52
Ref: TM-T1456
| 10mg | To inquire |
Estimated delivery in United States, on Wednesday 6 Nov 2024
HDAC6-IN-19
HDAC6-IN-19 (Compound 14g), an HDAC6 inhibitor with an IC50 of 2.68 nM, additionally inhibits HDAC1, …
Formula:
C26H23ClN4O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
474.94
Ref: TM-T78839
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 6 Nov 2024
5-Hydroxymethyl-2'-deoxycytidine
CAS:7226-77-9
5-Hydroxymethyl-2'-deoxycytidine is an oxidized derivative of 5-methyl-2'-deoxycytidine (5-mdC) in DNA, causing DNA damage reactions, chromosomal …
Formula:
C10H15N3O5
Purity:
99.8%
Color and Shape:
Liquid
Molecular weight:
257.24
Ref: TM-T40834
| 1mg | 40.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 199.00 € | ||
| 50mg | 316.00 € | ||
| 100mg | 477.00 € | ||
| 500mg | 1,012.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Wednesday 6 Nov 2024
AZD-9574
CAS:2756333-39-6
AZD-9574 is a selective inhibitor of PARP1 at the sites of SSBs.
Formula:
C21H22F2N6O2
Purity:
98.39% - 98.55%
Color and Shape:
Solid
Molecular weight:
428.44
Ref: TM-T9756
| 1mg | 115.00 € | ||
| 2mg | 165.00 € | ||
| 5mg | 273.00 € | ||
| 10mg | 437.00 € | ||
| 25mg | 772.00 € | ||
| 50mg | 1,104.00 € | ||
| 100mg | 1,471.00 € |
Estimated delivery in United States, on Wednesday 6 Nov 2024
Pterine-6-carboxylic acid
CAS:948-60-7
6-Carboxypterin, a folic acid breakdown product, is used to research UVA-induced DNA damage.
Formula:
C7H5N5O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
207.15
Ref: TM-TN6988
| 1mg | 113.00 € | ||
| 5mg | 270.00 € | ||
| 10mg | 425.00 € | ||
| 25mg | 768.00 € | ||
| 50mg | 1,016.00 € |
Estimated delivery in United States, on Wednesday 6 Nov 2024
Gimatecan HCl
Gimatecan HCl (ST1481 HCL) is a potent topoisomerase I inhibitor. Gimatecan is an orally bioavailable …
Formula:
C25H26ClN3O5
Purity:
97.04%
Color and Shape:
Soild
Molecular weight:
483.94
Ref: TM-T21319L
| 1mg | 46.00 € | ||
| 2mg | 57.00 € | ||
| 5mg | 79.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 187.00 € | ||
| 50mg | 280.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Wednesday 6 Nov 2024
Ru3
Ru3 is a poly(ADP-ribose) polymerase 1 (PARP1) inhibitor that prompts apoptosis in MCF-7 cells through …
Purity:
98%
Ref: TM-T81249
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 6 Nov 2024
MDL-800
CAS:2275619-53-7
MDL-800 is a SIRT6 modulator with antitumor activity for the study of hepatocellular carcinoma and …
Formula:
C21H16BrCl2FN2O6S2
Purity:
100%
Color and Shape:
Solid
Molecular weight:
626.3
Ref: TM-T64529
| 1mg | 55.00 € | ||
| 5mg | 116.00 € | ||
| 10mg | 171.00 € | ||
| 25mg | 280.00 € | ||
| 50mg | 421.00 € | ||
| 100mg | 618.00 € | ||
| 500mg | 1,290.00 € |
Estimated delivery in United States, on Friday 8 Nov 2024
CHDI-390576
CAS:1629729-98-1
CHDI-390576 is an HDAC inhibitor that inhibits class IIa HDAC 4, HDAC 5, HDAC 7, …
Formula:
C19H13F4N3O2
Purity:
99.03% - ≥98%
Color and Shape:
Solid
Molecular weight:
391.32
Ref: TM-T14947
| 1mg | 50.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 159.00 € | ||
| 25mg | 299.00 € | ||
| 50mg | 441.00 € | ||
| 100mg | 650.00 € |
Estimated delivery in United States, on Friday 8 Nov 2024
Azoxymethane
CAS:25843-45-2
Azoxymethane (AOM) is a DNA damaging agent that induces cancer and can be used in …
Formula:
C2H6N2O
Color and Shape:
Solid
Molecular weight:
74.08
Ref: TM-T73719
| 5mg (337.47mM*200μL in Water) | 392.00 € | ||
| 10mg (337.47mM*400μL in Water) | 689.00 € |
Estimated delivery in United States, on Friday 8 Nov 2024
Neogrifolin
CAS:23665-96-5
Neogrifolin is a potential candidate for osteosarcoma, it can induce concentration- and time-dependent suppression of …
Formula:
C22H32O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
328.49
Ref: TM-TN4637
| 5mg | 1,665.00 € | ||
| 1mL*10mM (DMSO) | 2,074.00 € |
Estimated delivery in United States, on Friday 8 Nov 2024
BRD7586
CAS:895460-70-5
BRD7586 is a cell-permeable small molecule inhibitor of SpCas9 that enhances SpCas9 specificity.
Formula:
C17H14ClN3O3S2
Purity:
99.03%
Color and Shape:
Solid
Molecular weight:
407.89
Ref: TM-T73444
| 1mg | 61.00 € | ||
| 5mg | 100.00 € | ||
| 10mg | 168.00 € | ||
| 25mg | 359.00 € | ||
| 50mg | 615.00 € | ||
| 100mg | 856.00 € | ||
| 500mg | 1,711.00 € |
Estimated delivery in United States, on Friday 8 Nov 2024
Exatecan
CAS:171335-80-1
Exatecan (DX-8951f) is a DNA topoisomerase I (TOP1) inhibitor with an IC50 value of 2.2 …
Formula:
C24H22FN3O4
Purity:
99.64% - 99.84%
Color and Shape:
Solid
Molecular weight:
435.45
Ref: TM-T11249
| 10mg | 35.00 € | ||
| 25mg | 69.00 € | ||
| 50mg | 90.00 € | ||
| 100mg | 133.00 € | ||
| 500mg | 316.00 € |
Estimated delivery in United States, on Friday 8 Nov 2024
RGFP966 (E-isomer)
CAS:1396841-57-8
RGFP966 is an HDAC3 inhibitor with IC50 of 0.08 μM, exhibits >200-fold selectivity over other …
Formula:
C21H19FN4O
Purity:
99.1%
Color and Shape:
Solid
Molecular weight:
362.4
Ref: TM-T6286
| 5mg | 36.00 € | ||
| 10mg | 52.00 € | ||
| 25mg | 85.00 € | ||
| 50mg | 109.00 € | ||
| 100mg | 165.00 € |
Estimated delivery in United States, on Friday 8 Nov 2024
IndiMitecan
CAS:915360-05-3
IndiMitecan (LMP776) is an inhibitor of topoisomerase I (Top1) with anticancer activities [1].
Formula:
C25H21N3O6
Purity:
98.25%
Color and Shape:
Soild
Molecular weight:
459.45
Ref: TM-T60200
| 1mg | 93.00 € | ||
| 5mg | 194.00 € | ||
| 10mg | 299.00 € | ||
| 25mg | 490.00 € | ||
| 50mg | 686.00 € | ||
| 100mg | 965.00 € |
Estimated delivery in United States, on Friday 8 Nov 2024
2’-Deoxy-2’-fluoro-β-D-arabinocytidine hydrochloride
CAS:25183-22-6
2'-Deoxy-2'-fluoro-beta-D-arabinocytidine HCl inhibits DNA methyltransferase with potential anti-tumor properties.
Formula:
C9H13ClFN3O4
Purity:
99.69%
Color and Shape:
Solid
Molecular weight:
281.67
Ref: TM-TNU0425
| 1mg | 182.00 € | ||
| 5mg | 401.00 € | ||
| 10mg | 591.00 € | ||
| 25mg | 917.00 € | ||
| 50mg | 1,262.00 € | ||
| 100mg | 1,698.00 € | ||
| 500mg | 3,431.00 € |
Estimated delivery in United States, on Friday 8 Nov 2024
5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine
CAS:23669-79-6
5'-O-DMT-dU, a dUTPase inhibitor (Ki >1 mM) for E. coli, is used in DNA synthesis.
Formula:
C30H30N2O7
Color and Shape:
Solid
Molecular weight:
530.57
Ref: TM-T39912
| 100mg | 50.00 € | ||
| 1mL*10mM (DMSO) | 50.00 € |
Estimated delivery in United States, on Friday 8 Nov 2024
Talazoparib tosylate
CAS:1373431-65-2
Talazoparib tosylate is a novel and potent PARP1/2 (n IC50: 0.57 nM for PARP1).
Formula:
C26H22F2N6O4S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
552.55
Ref: TM-T16979
| 2mg | 52.00 € |
Estimated delivery in United States, on Friday 8 Nov 2024
