NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
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Nimbolide
CAS:25990-37-8
Nimbolide, from neem, inhibits CDK4/6, NF-κB, Wnt, PI3K-Akt, MAPK, JAK-STAT pathways and induces apoptosis.
Formula:
C27H30O7
Purity:
95.84% - 99.4%
Color and Shape:
Solid
Molecular weight:
466.52
Ref: TM-T16324
| 1mg | 87.00 € | ||
| 5mg | 212.00 € | ||
| 10mg | 368.00 € | ||
| 25mg | 792.00 € | ||
| 50mg | 1,049.00 € | ||
| 100mg | 1,420.00 € | ||
| 1mL*10mM (DMSO) | 257.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
MRT67307
CAS:1190378-57-4
Through its effects on ULK1 and ULK2, MRT67307 blocks autophagy.
Formula:
C26H36N6O2
Purity:
99.25% - 99.79%
Color and Shape:
Solid
Molecular weight:
464.6
Ref: TM-T0097
| 1mg | 40.00 € | ||
| 5mg | 83.00 € | ||
| 10mg | 123.00 € | ||
| 25mg | 235.00 € | ||
| 50mg | 451.00 € | ||
| 100mg | 643.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Naringin dihydrochalcone
CAS:18916-17-1
Naringin dihydrochalcone (Naringin DC) is an inhibitor of CYP enzymes, used as an artificial sweetener.
Formula:
C27H34O14
Purity:
99.16%
Color and Shape:
Solid Powder
Molecular weight:
582.55
Ref: TM-T2761
| 1g | 40.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
RIPK1-IN-7
CAS:2300982-44-7
RIPK1-IN-7: Strong, selective RIPK1 inhibitor (Kd=4 nM, IC50=11 nM) with great antimetastasis effects in B16 …
Formula:
C25H22F3N5O2
Purity:
98.02%
Color and Shape:
Solid
Molecular weight:
481.47
Ref: TM-T12731
| 1mg | 89.00 € | ||
| 5mg | 209.00 € | ||
| 10mg | 318.00 € | ||
| 25mg | 493.00 € | ||
| 50mg | 682.00 € | ||
| 100mg | 909.00 € | ||
| 1mL*10mM (DMSO) | 225.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
(E/Z)-BCI
CAS:15982-84-0
(E/Z)-BCI (NSC-150117), a dual-specificity phosphatase 6 (DUSP6) inhibitor with anti-inflammatory properties, reduces LPS-induced inflammatory mediators …
Formula:
C22H23NO
Purity:
98.55%
Color and Shape:
Solid
Molecular weight:
317.42
Ref: TM-T11139
| 1mg | 78.00 € | ||
| 5mg | 153.00 € | ||
| 10mg | 272.00 € | ||
| 25mg | 435.00 € | ||
| 50mg | 615.00 € | ||
| 100mg | 817.00 € | ||
| 200mg | 1,080.00 € | ||
| 1mL*10mM (DMSO) | 164.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
DRI-C21045
CAS:2101765-81-3
Dri-c21045 inhibits NF-kB (IC50=17.1μM) and B cell proliferation (IC50=4.5μM), selectively blocking CD40-CD40L interaction (IC50=0.17μM).
Formula:
C32H24N2O7S
Purity:
98.10%
Color and Shape:
Solid
Molecular weight:
580.61
Ref: TM-T11096
| 5mg | 50.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 133.00 € | ||
| 50mg | 230.00 € | ||
| 100mg | 343.00 € | ||
| 200mg | 487.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
TBK1/IKKε-IN-2
CAS:1292310-49-6
TBK1/IKKε-IN-2 is a dual inhibitor of TBK1 and IKKε.
Formula:
C26H27N5O3
Purity:
98.89%
Color and Shape:
Solid
Molecular weight:
457.52
Ref: TM-T15559
| 1mg | 90.00 € | ||
| 5mg | 184.00 € | ||
| 10mg | 299.00 € | ||
| 25mg | 476.00 € | ||
| 50mg | 645.00 € | ||
| 100mg | 827.00 € | ||
| 1mL*10mM (DMSO) | 187.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
5-Aminosalicylic Acid
CAS:89-57-6
5-ASA, an anti-inflammatory salicylate, treats inflammatory bowel disease, active part of sulphalazine.
Formula:
C7H7NO3
Purity:
97.88% - 99.98%
Color and Shape:
Purplish-Tan Solid Powder
Molecular weight:
153.14
Ref: TM-T0646
| 500mg | 49.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
RIPK2-IN-5
CAS:2885227-09-6
RIPK2-IN-5 is a receptor-interacting protein kinase 2 (RIPK2) inhibitor with potential anti-inflammatory activity for the …
Formula:
C21H14N4S
Purity:
98.85%
Color and Shape:
Soild
Molecular weight:
354.43
Ref: TM-T83640
| 5mg | 47.00 € | ||
| 10mg | 69.00 € | ||
| 25mg | 125.00 € | ||
| 50mg | 195.00 € | ||
| 100mg | 307.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
IRAK4-IN-24
IRAK4-IN-24 (compound 16), a potent IRAK4 inhibitor, exhibits high clearance (Cl) and low oral bioavailability.
Formula:
C19H19N5O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
365.39
Ref: TM-T78744
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
BI1543673
BI1543673 is an inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK4). It can diminish inflammatory responses …
Ref: TM-T200483
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Anti-inflammatory agent 48
Anti-inflammatory agent 48 functions by inhibiting the NF-κB signaling pathway and activating HO-1 expression, characterizing …
Formula:
C24H21Cl2NO3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
442.33
Ref: TM-T79507
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Ref: TM-T200684
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
RIPK1-IN-25
RIPK1-IN-25 (WL8) is a RIPK1 inhibitor with blood-brain barrier permeability, displaying an EC50 of 19.9 …
Ref: TM-T200657
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
IRAK4-IN-26
IRAK4-IN-26 (Compound 21), an IRAK4 inhibitor with an IC50 of 6.2 nM, exhibits an oral …
Formula:
C22H23N5O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
405.45
Ref: TM-T79448
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
IRAK4-IN-27
IRAK4-IN-27 (Compound 22) is a potent and selective IRAK4 inhibitor, demonstrating an IC50 of 8.7 …
Formula:
C23H22N6O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
430.46
Ref: TM-T79485
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Selinidin
CAS:19427-82-8
Selinidin decreases phosphorylation of phospholipase C-gamma1, p38 mitogen-activated protein kinase, and IkappaB-alpha upon FcepsilonRI stimulation.
Formula:
C19H20O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
328.364
Ref: TM-TN4986
| 5mg | 510.00 € | ||
| 1mL*10mM (DMSO) | 519.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
ACHP
CAS:406208-42-2
ACHP (IKK-2 Inhibitor VIII) is a novel selective and potent IKK inhibitor with inhibitory effects …
Formula:
C21H24N4O2
Purity:
98.66%
Color and Shape:
Solid
Molecular weight:
364.44
Ref: TM-T22021
| 1mg | 52.00 € | ||
| 5mg | 105.00 € | ||
| 10mg | 157.00 € | ||
| 25mg | 251.00 € | ||
| 50mg | 367.00 € | ||
| 100mg | 625.00 € | ||
| 200mg | 1,019.00 € | ||
| 500mg | 2,037.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
IRAK4-IN-25
IRAK4-IN-25 (compound 38), a potent oral IRAK4 inhibitor (IC50 = 7.3 nM) with low clearance …
Formula:
C23H25N5O4
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
435.48
Ref: TM-T79447
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
(−)-N-Hydroxyapiosporamide
CAS:1205676-02-3
(−)-N-Hydroxyapiosporamide (NHAP), an alkaloid, serves as an NF-κB inhibitor and demonstrates significant antitumor activity both …
Formula:
C24H31NO7
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
445.51
Ref: TM-T79933
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
