TLR
Toll-like receptors (TLRs) are a class of proteins that play a critical role in the innate immune system by recognizing pathogen-associated molecular patterns (PAMPs) and initiating immune responses. TLRs are involved in detecting a wide range of pathogens, including bacteria, viruses, and fungi, and are essential for the activation of inflammatory signaling pathways. Dysregulation of TLR signaling is associated with chronic inflammatory diseases, autoimmune disorders, and cancer. At CymitQuimica, we offer a variety of high-quality TLR modulators to support your research in innate immunity, inflammation, and infectious disease.
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PF-4878691
CAS:532959-63-0
PF-4878691 (3M-852A) is an effective and selective Toll-like receptor 7 agonists modelled. It is used …
Formula:
C17H23N5O2S
Purity:
98.43%
Color and Shape:
Solid
Molecular weight:
361.46
Ref: TM-T16506
| 1mg | 47.00 € | ||
| 5mg | 142.00 € | ||
| 10mg | 230.00 € | ||
| 25mg | 500.00 € | ||
| 50mg | 828.00 € | ||
| 100mg | 1,345.00 € | ||
| 1mL*10mM (DMSO) | 156.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
CU-CPT22
CAS:1416324-85-0
CU-CPT22: first TLR1/2 complex probe, binds at TLR1/2 interface (IC50=0.58μM), inhibits Pam3CSK4 binding (Ki=0.41μM).
Formula:
C19H22O7
Purity:
98.66%
Color and Shape:
Solid
Molecular weight:
362.37
Ref: TM-T15020
| 1mg | 52.00 € | ||
| 2mg | 74.00 € | ||
| 5mg | 103.00 € | ||
| 10mg | 170.00 € | ||
| 25mg | 311.00 € | ||
| 50mg | 463.00 € | ||
| 100mg | 676.00 € | ||
| 1mL*10mM (DMSO) | 114.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
SM-276001
CAS:473930-22-2
SM-276001 is a potent selective agonist of TLR7,and is an orally active interferon (IFN) inducer.
Formula:
C16H21N7O
Purity:
99.37%
Color and Shape:
Solid
Molecular weight:
327.38
Ref: TM-T12933
| 1mg | 62.00 € | ||
| 5mg | 135.00 € | ||
| 10mg | 196.00 € | ||
| 25mg | 351.00 € | ||
| 50mg | 527.00 € | ||
| 100mg | 763.00 € | ||
| 200mg | 1,026.00 € | ||
| 1mL*10mM (DMSO) | 147.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
IAXO-102
CAS:1115270-63-7
IAXO-102 is a TLR4 antagonist that negatively regulates TLR4 signaling.
Formula:
C35H71NO5
Purity:
≥98%
Color and Shape:
Solid
Molecular weight:
585.94
Ref: TM-T11598
| 1mg | 96.00 € | ||
| 2mg | 131.00 € | ||
| 5mg | 246.00 € | ||
| 10mg | 394.00 € | ||
| 25mg | 640.00 € | ||
| 50mg | 912.00 € | ||
| 100mg | 1,254.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
CU-T12-9
CAS:1821387-73-8
CU-T12-9 is a potent TLR1/2 agonist(EC50 of 52.9 nM in HEK-Blue hTLR2 SEAP assay).
Formula:
C17H13F3N4O2
Purity:
99.93%
Color and Shape:
Solid
Molecular weight:
362.31
Ref: TM-T15017
| 1mg | 104.00 € | ||
| 2mg | 147.00 € | ||
| 5mg | 213.00 € | ||
| 10mg | 278.00 € | ||
| 25mg | 350.00 € | ||
| 50mg | 423.00 € | ||
| 100mg | 613.00 € | ||
| 500mg | 1,263.00 € | ||
| 1mL*10mM (DMSO) | 187.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
TLR7/8 agonist 3
CAS:642473-95-8
TLR7/8 agonist 3 is a potent agonist of TLR7 and TLR8.
Formula:
C17H23N5O
Purity:
99.93%
Color and Shape:
Solid
Molecular weight:
313.4
Ref: TM-T13167
| 1mg | 62.00 € | ||
| 5mg | 136.00 € | ||
| 10mg | 218.00 € | ||
| 25mg | 355.00 € | ||
| 50mg | 490.00 € | ||
| 100mg | 676.00 € | ||
| 200mg | 910.00 € | ||
| 1mL*10mM (DMSO) | 150.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
CU-CPT17e
CAS:2109805-75-4
CU-CPT17e is a potent agonist of TLR(TLR3, TLR8, and TLR9).
Formula:
C27H24N2O8
Purity:
98.49%
Color and Shape:
Solid
Molecular weight:
504.49
Ref: TM-T10899
| 1mg | 198.00 € | ||
| 5mg | 412.00 € | ||
| 10mg | 603.00 € | ||
| 25mg | 917.00 € | ||
| 50mg | 1,291.00 € | ||
| 100mg | 1,736.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Chloranil
CAS:118-75-2
Chloranil (tetrachloro-p-benzoquinone) induces inflammation and neurological dysfunction and can be used to model inflammation in …
Formula:
C6Cl4O2
Purity:
99.38%
Color and Shape:
Liquid
Molecular weight:
245.88
Ref: TM-T80673
| 1g | 34.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
Tomaralimab
CAS:1449294-76-1
Tomaralimab (OPN-305) is a humanized IgG4 monoclonal antibody targeting TLR2. Tomarlimab is used to study …
Purity:
> 95% - SDS-PAGE:95% SEC-HPLC:99.99%
Color and Shape:
Liquid
Molecular weight:
145.32 kDa
Ref: TM-T76975
| 1mg | 207.00 € | ||
| 5mg | 514.00 € | ||
| 10mg | 740.00 € | ||
| 25mg | 1,137.00 € | ||
| 50mg | 1,533.00 € | ||
| 100mg | 2,062.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
VB 201
CAS:630112-41-3
VB 201 is a small molecule of oxidized phospholipids with anti-inflammatory activity that can be …
Formula:
C29H60NO8P
Purity:
100%
Color and Shape:
Solid
Molecular weight:
581.76
Ref: TM-T29099L
| 1mg | 185.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
TLR7/8/9 antagonist 2
CAS:2920729-91-3
TLR7/8/9 antagonist 2 is an orally active and highly bioavailable vTLR7/8/9 antagonist. It inhibits HEK/hTLR7, …
Formula:
C23H31N7
Purity:
98%
Color and Shape:
Soild
Molecular weight:
405.54
Ref: TM-T72035
| Undefined size | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
CU-115
CAS:2471982-20-2
CU-115 is a selective and potent TLR8 antagonist with IC50 of 1.04 µM and = …
Formula:
C21H11F7INO2
Purity:
100%
Color and Shape:
Solid
Molecular weight:
569.21
Ref: TM-T9645
| 1mg | 57.00 € | ||
| 5mg | 139.00 € | ||
| 10mg | 218.00 € | ||
| 25mg | 376.00 € | ||
| 50mg | 527.00 € | ||
| 100mg | 722.00 € | ||
| 1mL*10mM (DMSO) | 169.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
BMS-905
CAS:2205846-49-5
BMS-905 is a potent dual inhibitors of TLR7 and TLR8 with good selectivity against TLR9 …
Formula:
C23H29N3
Purity:
98%
Color and Shape:
Soild
Molecular weight:
347.5
Ref: TM-T60052
| 1mg | 73.00 € | ||
| 5mg | 167.00 € | ||
| 10mg | 254.00 € | ||
| 25mg | 420.00 € | ||
| 50mg | 592.00 € | ||
| 100mg | 799.00 € | ||
| 500mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
Semapimod tetrahydrochloride
CAS:164301-51-3
Semapimod tetrahydrochloride (CPSI-2364 tetrahydrochloride) is a mitogen-activated protein kinase blocker and pro-inflammatory cytokine production inhibitor.
Formula:
C34H56Cl4N18O2
Purity:
99.8%
Color and Shape:
Solid
Molecular weight:
890.74
Ref: TM-T35593
| 1mg | 98.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
TLR7 agonist 3
CAS:1229024-78-5
TLR7 agonist 3 is a Toll-like receptor 7 (TLR7) agonist that has anticancer activity and …
Formula:
C18H24N4O
Purity:
99.27%
Color and Shape:
Liquid
Molecular weight:
312.41
Ref: TM-T38614
| 1mg | 112.00 € | ||
| 5mg | 268.00 € | ||
| 10mg | 444.00 € | ||
| 25mg | 730.00 € | ||
| 50mg | 1,037.00 € | ||
| 100mg | 1,379.00 € | ||
| 1mL*10mM (DMSO) | 295.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Toll-like receptor modulator
CAS:926927-42-6
Toll-like receptor modulator is a TLR7/8 modulator, which modulates immune function.
Formula:
C15H13F5N2O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
348.27
Ref: TM-T13182
| 2mg | 70.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Imiquimod hydrochloride
CAS:99011-78-6
Imiquimod hydrochloride (R 837 hydrochloride) is a TLR7 agonist and immune response modulator with antiviral …
Formula:
C14H17ClN4
Purity:
99.18%
Color and Shape:
Solid
Molecular weight:
276.77
Ref: TM-T22091
| 50mg | 38.00 € | ||
| 100mg | 51.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Robinin
CAS:301-19-9
Robinin: a kaempferol-derived flavone glycoside with antibacterial, diuretic traits; minimal effect on Colo 320 MDR1/LRP …
Formula:
C33H40O19
Purity:
98% - 98.91%
Color and Shape:
Solid
Molecular weight:
740.66
Ref: TM-T2S0265
| 1mg | 74.00 € | ||
| 5mg | 158.00 € | ||
| 10mg | 226.00 € | ||
| 25mg | 367.00 € | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 11 Dec 2024
TLR7 agonist 2
CAS:1642857-69-9
TLR7 agonist 2 (TLR7-IN-1) is a specific and effective Toll-like Receptor 7 (TLR7) agonist (LEC=0.4 …
Formula:
C17H16N6O2
Purity:
98.98%
Color and Shape:
Solid
Molecular weight:
336.35
Ref: TM-T4258
| 1mg | 154.00 € | ||
| 2mg | 237.00 € | ||
| 5mg | 485.00 € | ||
| 10mg | 701.00 € | ||
| 25mg | 1,087.00 € | ||
| 50mg | 1,467.00 € | ||
| 100mg | 1,986.00 € | ||
| 1mL*10mM (DMSO) | 364.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
TLR7/8 agonist 1
CAS:1258457-59-8
TLR7/8 agonist 1 is a toll-like receptor TLR7/TLR8 agonist with anticancer and antiviral activities and …
Formula:
C22H25N5
Color and Shape:
Liquid
Molecular weight:
359.47
Ref: TM-T71108
| 1mg | 51.00 € | ||
| 5mg | 110.00 € | ||
| 10mg | 171.00 € | ||
| 25mg | 360.00 € | ||
| 50mg | 619.00 € | ||
| 100mg | 1,023.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
