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MAPK
MAP4K4-IN-3
CAS:1811510-58-3
MAP4K4-IN-3 may be a viable target for antidiabetic agents, a serine/threonine protein kinase.
Formula:
C15H12ClN5
Purity:
99.50%
Color and Shape:
Solid
Molecular weight:
297.74
Estimated delivery in United States, on Thursday 3 Feb 2022
K-Ras(G12C) inhibitor 12
CAS:1469337-95-8
K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of oncogenic K-Ras(G12C).
Formula:
C15H17ClIN3O3
Purity:
98.0%
Color and Shape:
solid
Molecular weight:
449.67
Estimated delivery in United States, on Thursday 3 Feb 2022
JAK2/FLT3-IN-1
CAS:2387765-27-5
JAK2/FLT3-IN-1 has anti-cancer activity. JAK2/FLT3-IN-1 is a potent and orally effective dual JAK2/FLT3 (Janus kinase …
Formula:
C25H34FN7O
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
467.58
Estimated delivery in United States, on Thursday 3 Feb 2022
JNK-IN-8
CAS:1410880-22-6
JNK-IN-8 is an irreversible JNK1/2/4 inhibitor (IC50: 4.7/18.7/1 nM). The selectivity is higher 10-fold than …
Formula:
C29H29N7O2
Purity:
100.00%
Color and Shape:
solid
Molecular weight:
507.59
Estimated delivery in United States, on Thursday 3 Feb 2022
AZD8330
CAS:869357-68-6
AZD8330 is a novel, selective, non-ATP competitive MEK 1/2 inhibitor with IC50 of 7 nM. …
Formula:
C16H17FIN3O4
Purity:
98.86%
Color and Shape:
solid
Molecular weight:
461.23
Estimated delivery in United States, on Thursday 3 Feb 2022
LY364947
CAS:396129-53-6
LY364947 is a potent ATP-competitive inhibitor of TGFR-I.
Formula:
C17H12N4
Purity:
99.65%
Color and Shape:
solid
Molecular weight:
272.3
Estimated delivery in United States, on Thursday 3 Feb 2022
Kobe0065
CAS:436133-68-5
Kobe0065 is a novel and effective small-molecule compound inhibiting RasRaf interaction by SBDD; shows potent …
Formula:
C15H11ClF3N5O4S
Purity:
99.76%
Color and Shape:
solid
Molecular weight:
449.79
Estimated delivery in United States, on Thursday 3 Feb 2022
SC202671
CAS:312917-14-9
TCS JNK 5a is an effective, specific inhibitor of JNK3(pIC50= 6.7), JNK2(pIC50=6.5).
Formula:
C20H16N2OS
Purity:
99.22%
Color and Shape:
solid
Molecular weight:
332.42
Estimated delivery in United States, on Thursday 3 Feb 2022
eFT508
CAS:1849590-01-7
eFT508 is a potent, highly selective MNK1 and MNK2 inhibitor with IC50 value of 1-2 …
Formula:
C17H20N6O2
Purity:
99.67%
Color and Shape:
Solid
Molecular weight:
340.39
Estimated delivery in United States, on Thursday 3 Feb 2022
AMG900
CAS:945595-80-2
AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with …
Formula:
C28H21N7OS
Purity:
98.40%
Color and Shape:
solid
Molecular weight:
503.58
Estimated delivery in United States, on Thursday 3 Feb 2022
RO5126766
CAS:946128-88-7
RO5126766 (CH5126766) is a dual RAF/MEK inhibitor with IC50 of 8.2 nM, 19 nM, 56 …
Formula:
C21H18FN5O5S
Purity:
98.30%
Molecular weight:
471.46
Estimated delivery in United States, on Thursday 3 Feb 2022
VX702
CAS:745833-23-2
VX-702 is a highly specific p38 MAPK inhibitor, 14-fold higher selectivity for the p38 than …
Formula:
C19H12F4N4O2
Purity:
99.00%
Color and Shape:
solid
Molecular weight:
404.3
Estimated delivery in United States, on Thursday 3 Feb 2022
MLN2480
CAS:1096708-71-2
MLN2480 is an oral, selective pan-Raf kinase inhibitor in Clinicalal trials.
Formula:
C17H12Cl2F3N7O2S
Purity:
99.77%
Color and Shape:
solid
Molecular weight:
506.29
Estimated delivery in United States, on Thursday 3 Feb 2022
TAK733
CAS:1035555-63-5
MEK Inhibitor TAK-733 is an orally bioavailable small-molecule inhibitor of MEK1 and MEK2 (MEK1/2) with …
Formula:
C17H15F2IN4O4
Purity:
98.31%
Color and Shape:
solid
Molecular weight:
504.23
Estimated delivery in United States, on Thursday 3 Feb 2022
PD318088
CAS:391210-00-7
PD318088 is a non-ATP competitive allosteric MEK1/2 inhibitor, binding simultaneously with ATP in a region …
Formula:
C16H13BrF3IN2O4
Purity:
99.69%
Color and Shape:
solid
Molecular weight:
561.09
Estimated delivery in United States, on Thursday 3 Feb 2022
Losmapimod
CAS:585543-15-3
Losmapimod (GW856553X; SB856553; GSK-AHAB) is a specific, potent, and orally active p38 MAPK inhibitor (pKi: …
Formula:
C22H26FN3O2
Purity:
98.56%
Color and Shape:
solid
Molecular weight:
383.46
Estimated delivery in United States, on Thursday 3 Feb 2022
BMS582949
CAS:623152-17-0
BMS-582949 is a potent and selective p38 mitogen-activated protein kinase (p38 MAPK) inhibitor with IC50 …
Formula:
C22H26N6O2
Purity:
97.71%
Color and Shape:
solid
Molecular weight:
406.48
Estimated delivery in United States, on Thursday 3 Feb 2022
PLX7904
CAS:1393465-84-3
PLX7904, also known as PB04, is a potent and selective paradox-breaker RAF inhibitor. It is …
Formula:
C24H22F2N6O3S
Purity:
98.0%
Color and Shape:
Solid
Molecular weight:
512.53
Estimated delivery in United States, on Thursday 3 Feb 2022
KO-947
CAS:1695533-89-1
KO-947 is a potent and specific inhibitor of ERK1/2 kinases.
Formula:
C21H17N5O
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
355.39
Estimated delivery in United States, on Thursday 3 Feb 2022
Vacquinol-1
CAS:5428-80-8
Vacquinol-1 is an MKK4 activator, which rapidly and selectively induces glioma cell death.
Formula:
C21H21ClN2O· 2HCl
Purity:
98.0%
Color and Shape:
solid
Molecular weight:
425.78
Estimated delivery in United States, on Thursday 3 Feb 2022
GNE3511
CAS:1496581-76-0
GNE-3511 is a potent and selective dual leucine zipper kinase inhibitors.
Formula:
C23H26F2N6O
Purity:
99.37%
Color and Shape:
Solid
Molecular weight:
440.21
Estimated delivery in United States, on Thursday 3 Feb 2022
NVP-BHG712
CAS:940310-85-0
NVP-BHG712 is a specific EphB4 inhibitor with ED50 of 25 nM that discriminates between VEGFR …
Formula:
C26H20F3N7O
Purity:
97.96%
Color and Shape:
solid
Molecular weight:
503.49
Estimated delivery in United States, on Thursday 3 Feb 2022
RAF265
CAS:927880-90-8
RAF265 (CHIR-265) is a potent selective inhibitor of C-Raf/B-Raf/B-Raf V600E with IC50 of 3-60 nM, …
Formula:
C24H16F6N6O
Purity:
99.18%
Molecular weight:
518.41
Estimated delivery in United States, on Thursday 3 Feb 2022
Loureirin B
CAS:119425-90-0
Loureirin B can downregulate the expression of fibrosis-related molecules by regulating MMPs and TIMPs levels, …
Formula:
C18H20O5
Purity:
99.86%
Color and Shape:
solid
Molecular weight:
316.35
Estimated delivery in United States, on Thursday 3 Feb 2022
AZ 628
CAS:878739-06-1
AZ628 is a new pan-Raf inhibitor for BRAF, BRAFV600E, and c-Raf-1 with IC50 of 105 …
Formula:
C27H25N5O2
Molecular weight:
451.52
Estimated delivery in United States, on Thursday 3 Feb 2022
RAF709
CAS:1628838-42-5
RAF709 is a novel Raf kinase inhibitor with IC50s of 0.5 and 1.8 nM for …
Formula:
C28H29F3N4O4
Purity:
99.43%
Color and Shape:
Solid
Molecular weight:
542.21
Estimated delivery in United States, on Thursday 3 Feb 2022
APS-2-79
CAS:2002381-31-7
APS-2-79 is a MAPK antagonist that modulating KSR-dependent MAPK signalling by antagonizing RAF heterodimerization as …
Formula:
C23H21N3O3·HCl
Purity:
98.22%
Color and Shape:
Solid
Molecular weight:
423.89
Estimated delivery in United States, on Thursday 3 Feb 2022
FR180204
CAS:865362-74-9
FR180204 is a potent and selective ATP-competitive inhibitor of ERK1 and ERK2.
Formula:
C18H13N7
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
327.34
Estimated delivery in United States, on Thursday 3 Feb 2022
ZM 447439
CAS:331771-20-1
ZM 447439 is a selective and ATP-competitive inhibitor for Aurora A and Aurora B with …
Formula:
C29H31N5O4
Molecular weight:
513.59
Estimated delivery in United States, on Thursday 3 Feb 2022
NVP 231
CAS:362003-83-6
NVP-231 is a potent, specific and reversible CerK inhibitor(IC50=12±2 nM) that competitively inhibits ceramide binding …
Formula:
C25H25N3O2S
Purity:
97.88%
Color and Shape:
solid
Molecular weight:
431.55
Estimated delivery in United States, on Thursday 3 Feb 2022
K-Ras(G12C) inhibitor 9
CAS:1469337-91-4
K-Ras(G12C) inhibitor 9 is an allosteric inhibitor of oncogenic K-Ras(G12C).
Formula:
C16H21ClIN3O4S
Color and Shape:
solid
Molecular weight:
513.78
Estimated delivery in United States, on Thursday 3 Feb 2022
GDC0879
CAS:905281-76-7
GDC-0879 is a novel, potent and selective B-Raf inhibitor with IC50 of 0.13 nM with …
Formula:
C19H18N4O2
Purity:
96.74%
Color and Shape:
solid
Molecular weight:
334.37
Estimated delivery in United States, on Thursday 3 Feb 2022
Binimetinib
CAS:606143-89-9
Binimetinib (MEK162, ARRY-162, ARRY-438162) is an orally available inhibitor of MEK1/2 (IC50: 12 nM) in …
Formula:
C17H15BrF2N4O3
Purity:
99.00%
Color and Shape:
solid
Molecular weight:
441.23
Estimated delivery in United States, on Thursday 3 Feb 2022
DB07268
CAS:929007-72-7
DB07268 is a potent and selective JNK1 inhibitor.
Formula:
C17H15N5O2
Purity:
98.21%
Color and Shape:
Solid
Molecular weight:
321.33
Estimated delivery in United States, on Thursday 3 Feb 2022
GW5074
CAS:220904-83-6
GW5074(IC50=9 nM) is an effective and specific c-Raf inhibitor. It has no effect on the …
Formula:
C15H8Br2INO2
Purity:
97.30%
Color and Shape:
solid
Molecular weight:
520.94
Estimated delivery in United States, on Thursday 3 Feb 2022
(E)-Necrosulfonamide
CAS:1360614-48-7
(E)-Necrosulfonamide is an inhibitor of necroptosis. Blocks mixed lineage kinase domain-like protein (MLKL), a critical …
Formula:
C18H15N5O6S2
Purity:
99.04%
Color and Shape:
Solid
Molecular weight:
461.47
Estimated delivery in United States, on Thursday 3 Feb 2022
SKF86002
CAS:72873-74-6
SKF-86002 is an effective inhibitor of p38 MAP kinase (IC50: 0.5-1 uM); inhibits LPS-induced IL-1 …
Formula:
C16H12FN3S
Purity:
99.68%
Color and Shape:
solid
Molecular weight:
297.35
Estimated delivery in United States, on Thursday 3 Feb 2022
BI-78D3
CAS:883065-90-5
BI-78D3, a competitive JNK inhibitor. IC50 of BI-78D3 is 280 nM that displays >100 fold …
Formula:
C13H9N5O5S2
Purity:
99.95%
Color and Shape:
solid
Molecular weight:
379.37
Estimated delivery in United States, on Thursday 3 Feb 2022
SCH54292
CAS:188480-51-5
SCH-54292 is a GDP exchange inhibitor.
Formula:
C24H28N2O9S
Molecular weight:
520.55
Estimated delivery in United States, on Thursday 3 Feb 2022
ZM 336372
CAS:208260-29-1
ZM 336372 is a potent and selective c-Raf inhibitor.
Formula:
C23H23N3O3
Purity:
97.24%
Color and Shape:
solid
Molecular weight:
389.45
Estimated delivery in United States, on Thursday 3 Feb 2022
AS601245
CAS:345987-15-7
AS601245 is an inhibitor of the c-Jun NH2-terminal kinase (JNK), with neuroprotective properties.
Formula:
C20H16N6S
Color and Shape:
solid
Molecular weight:
372.45
Estimated delivery in United States, on Thursday 3 Feb 2022
TAK715
CAS:303162-79-0
TAK-715 is a p38 MAPK inhibitor for p38.
Formula:
C24H21N3OS
Purity:
98.51%
Molecular weight:
399.51
Estimated delivery in United States, on Thursday 3 Feb 2022
IQ-1S
CAS:23146-22-7
IQ-1S is an effective and specific c-Jun N-Terminal Kinase Inhibitor. IQ-1S inhibits murine delayed-type hypersensitivity. …
Formula:
C15H9N3O
Purity:
97.92%
Color and Shape:
Solid
Molecular weight:
247.25
Estimated delivery in United States, on Thursday 3 Feb 2022
Refametinib
CAS:923032-37-5
Refametinib (RDEA119, Bay 86-9766) is an effective, ATP non-competitive and specific inhibitor of MEK1/2 (IC50: …
Formula:
C19H20F3IN2O5S
Purity:
100.00%
Color and Shape:
solid
Molecular weight:
572.34
Estimated delivery in United States, on Thursday 3 Feb 2022
OTS514
CAS:1338540-63-8
OTS514 is a potent TOPK inhibitor. OTS514 exhibits a growth-suppressive effect on small cell lung …
Formula:
C21H20N2O2S
Color and Shape:
Solid
Molecular weight:
364.46
Estimated delivery in United States, on Thursday 3 Feb 2022
1588-A4
CAS:1698027-20-1
1588-A4 is an intermediate of ARS-1620 which is an atropisomeric selective KRASG12C inhibitor with desirable …
Formula:
C17H19BrClFN4O2
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
445.7
Estimated delivery in United States, on Thursday 3 Feb 2022
ERK-IN-3
CAS:2055597-12-9
ERK-IN-3 is a potent and orally active inhibitor of ERK. It inhibits ERK1/2 with low …
Formula:
C22H25ClFN7O2
Purity:
99.76%
Molecular weight:
473.93
Estimated delivery in United States, on Thursday 3 Feb 2022
CID25014542
CAS:220904-99-4
CID-25014542 is novel inhibitor of Raf kinases.
Formula:
C15H8Br2ClNO2
Purity:
100.00%
Color and Shape:
solid
Molecular weight:
429.49
Estimated delivery in United States, on Thursday 3 Feb 2022
Neflamapimod
CAS:209410-46-8
VX-745, a specific and effective inhibitor of p38(IC50=10 nM), is 22-fold greater specificity against p38 …
Formula:
C19H9Cl2F2N3OS
Purity:
99.02%
Color and Shape:
solid
Molecular weight:
436.26
Estimated delivery in United States, on Thursday 3 Feb 2022
BIX 02189
CAS:1265916-41-3
BIX02189 is a potent and selective inhibitor of MEK5 and ERK5(IC50 : 1.5 nM and …
Formula:
C27H28N4O2
Purity:
99.17%
Color and Shape:
Solid
Molecular weight:
440.54
Estimated delivery in United States, on Thursday 3 Feb 2022
I-37
CAS:2359690-13-2
I-37 is a novel benzylamino substituted pyridopyrimidinone as SOS1 inhibitor.
Formula:
C22H23F3N4O
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
416.45
Estimated delivery in United States, on Thursday 3 Feb 2022
6H05
CAS:1469338-01-9
6H05 is a selective, allosteric inhibitor of oncogenic mutant K-Ras(G12C).
Formula:
C20H30ClN3O2S3
Molecular weight:
476.12
Estimated delivery in United States, on Thursday 3 Feb 2022
Notoginsenoside R1
CAS:80418-24-2
Notoginsenoside R1 has been shown to exhibit antioxidant, antiapoptotic, anti-inflammatory, and immune-stimulatory properties.
Formula:
C47H80O18
Purity:
99.69%
Color and Shape:
solid
Molecular weight:
933.13
Estimated delivery in United States, on Thursday 3 Feb 2022
ERK-IN-2
ERK-IN-2 might lead to off-target toxicity and/or off-target activity at dose >10 μM.ERK-IN-2 is a …
Formula:
C16H18ClN5O2
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
347.8
Estimated delivery in United States, on Thursday 3 Feb 2022
ASTX029
CAS:2095719-92-7
ASTX029 is a selective and orally bioavailable extracellular signal-regulated kinases 1 and 2 (ERK 1/2) …
Formula:
C29H31ClFN5O5
Purity:
99.29%
Color and Shape:
Solid
Molecular weight:
584.04
Estimated delivery in United States, on Thursday 3 Feb 2022
AS601245.2TFA (345987-15-7 free base)
AS601245.2TFA is a cell-permeable Inhibitor of JNK (IC50s of 150, 220, and 70 nM for …
Formula:
NA
Purity:
100.00%
Molecular weight:
N/A
Estimated delivery in United States, on Thursday 3 Feb 2022
RO4987655
CAS:874101-00-5
RO4987655 is an orally active and highly selective MEK inhibitor (IC50: 5.2 nM for MEK1/MEK2).
Formula:
C20H19F3IN3O5
Purity:
98.21%
Color and Shape:
solid
Molecular weight:
565.28
Estimated delivery in United States, on Thursday 3 Feb 2022
SB590885
CAS:405554-55-4
SB590885 is an effective B-Raf inhibitor (Ki: 0.16 nM, in a cell-free assay). The selectivity …
Formula:
C27H27N5O2
Color and Shape:
solid
Molecular weight:
453.54
Estimated delivery in United States, on Thursday 3 Feb 2022
NQDI1
CAS:175026-96-7
NQDI-1 is a selective inhibitor of apoptosis signal-regulating kinase 1 (ASK1, MAP3K5) (IC50/Ki: 3 μM/500 …
Formula:
C19H13NO4
Purity:
97.19%
Color and Shape:
solid
Molecular weight:
319.31
Estimated delivery in United States, on Thursday 3 Feb 2022
AMG-548 hydrochloride (864249-60-5 free base)
AMG-548 hydrochloride is an orally active and selective p38 inhibitor (Ki: 0.5 nM) and shows …
Formula:
C29H28ClN5O
Molecular weight:
498.02
Estimated delivery in United States, on Thursday 3 Feb 2022
anemarsaponin B
CAS:139051-27-7
Anemarsaponin B has anti-inflammatory effect in LPS-treated RAW 264.7macrophages, the effect is associated with the …
Formula:
C45H74O18
Color and Shape:
Solid
Molecular weight:
903.06
Estimated delivery in United States, on Thursday 3 Feb 2022
Dabrafenib Mesylate
CAS:1195768-06-9
Dabrafenib Mesylate is a B-Raf inhibitor(IC50s of 0.6 and 5.0 nM for RafV600E and c-Raf, …
Formula:
C24H24F3N5O5S3
Purity:
99.45%
Color and Shape:
solid
Molecular weight:
615.66
Estimated delivery in United States, on Thursday 3 Feb 2022
Farrerol
CAS:24211-30-1
1. Farrerol has antioxidative activity.2. Farrerol modulates TAP and BNBD5 gene expression in mammary gland, …
Formula:
C17H16O5
Purity:
99.96%
Color and Shape:
solid
Molecular weight:
300.31
Estimated delivery in United States, on Thursday 3 Feb 2022
BAW2881
CAS:861875-60-7
BAW2881 is a potent and selective VEGFR inhibitor (vascular endothelial growth factor receptor tyrosine kinase …
Formula:
C22H15F3N4O2
Purity:
99.97%
Color and Shape:
Solid
Molecular weight:
424.38
Estimated delivery in United States, on Thursday 3 Feb 2022
Muramyl dipeptide
CAS:53678-77-6
Muramyl dipeptide is a synthetic immunoreactive peptide, consisting of N-acetyl muramic acid attached to a …
Formula:
C19H32N4O11
Purity:
98.00%
Molecular weight:
492.48
Estimated delivery in United States, on Thursday 3 Feb 2022
Momordin Ic
CAS:96990-18-0
Momordin Ic might represent a potential anticancer activity, by inducing apoptosis through oxidative stress-regulated mitochondrial …
Formula:
C41H64O13
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
764.93
Estimated delivery in United States, on Thursday 3 Feb 2022
Pseudolaric Acid B
CAS:82508-31-4
Pseudolaric acid B, a natural diterpenoid compound, is isolated from Pseudolarix kaempferi.
Formula:
C23H28O8
Color and Shape:
solid
Molecular weight:
432.18
Estimated delivery in United States, on Thursday 3 Feb 2022
SU3327
CAS:40045-50-9
SU3327 is a potent, selective and substrate-competitive inhibitor of JNK(IC50 of 0.7 μM).
Formula:
C5H3N5O2S3
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
261.3
Estimated delivery in United States, on Thursday 3 Feb 2022
Anisomycin
CAS:22862-76-6
Anisomycin is an antibiotic isolated from various Streptomyces species. It interferes with protein and DNA …
Formula:
C14H19NO4
Purity:
99.11%
Color and Shape:
White Crystalline Solid
Molecular weight:
265.3
Estimated delivery in United States, on Thursday 3 Feb 2022
BAY885
CAS:2307249-33-6
BAY885 is a new ERK5 inhibitor.
Formula:
C25H28F3N7O2
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
515.53
Estimated delivery in United States, on Thursday 3 Feb 2022
AZ7550 Mesylate (1421373-99-0 free base)
AZ7550 hydrochloride, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).
Formula:
C30H43N7O11S3
Molecular weight:
773.9
Estimated delivery in United States, on Thursday 3 Feb 2022
Pluripotin
CAS:839707-37-8
Pluripotin (SC1), which keep embryonic stem cell (ESC) self-renewal, is a dual inhibitor of extracellular …
Formula:
C27H25F3N8O2
Purity:
98.82%
Color and Shape:
solid
Molecular weight:
550.53
Estimated delivery in United States, on Thursday 3 Feb 2022
Talmapimod hydrochloride
CAS:309915-12-6
Talmapimod hydrochloride is a selective and ATP-competitive p38 inhibitor (IC50: 9 nM). It also shows …
Formula:
C27H31Cl2FN4O3
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
549.46
Estimated delivery in United States, on Thursday 3 Feb 2022
Cornuside
CAS:131189-57-6
1. Cornuside has immunomodulatory activity . 2. Cornuside suppresses expression levels of cytokine-induced proinflammatory and …
Formula:
C24H30O14
Purity:
99.59%
Color and Shape:
solid
Molecular weight:
542.49
Estimated delivery in United States, on Thursday 3 Feb 2022
CC-401 Hydrochloride
CAS:1438391-30-0
CC-401 is a second generation ATP-competitive anthrapyrazolone c-Jun N terminal kinase (JNK) inhibitor (Ki of …
Formula:
C22H25ClN6O
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
424.93
Estimated delivery in United States, on Thursday 3 Feb 2022
PLX4720
CAS:918505-84-7
PLX-4720 is a potent and selective inhibitor of B-Raf (V600E) (IC50: 13 nM), equally potent …
Formula:
C17H14ClF2N3O3S
Color and Shape:
solid
Molecular weight:
413.83
Estimated delivery in United States, on Thursday 3 Feb 2022
CC-90003
CAS:1621999-82-3
CC-90003 is a selective inhibitor of ERK 1/2. It has antitumor activity.
Formula:
C22H21F3N6O2
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
458.44
Estimated delivery in United States, on Thursday 3 Feb 2022
SB242235
CAS:193746-75-7
SB-242235 is a potent and selective p38 MAP kinase inhibitor that may be an effective …
Formula:
C19H20FN5O
Purity:
99.14%
Color and Shape:
solid
Molecular weight:
353.39
Estimated delivery in United States, on Thursday 3 Feb 2022
MEK inhibitor
CAS:334951-92-7
MEK inhibitor is a potent MEK inhibitor with antitumor potency.
Formula:
C26H26N4O2
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
426.51
Estimated delivery in United States, on Thursday 3 Feb 2022
NG25
CAS:1315355-93-1
NG25 is a potent dual TAK1 and MAP4K2 inhibitor, with IC50s of 149 nM and …
Formula:
C29H30F3N5O2
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
537.58
Estimated delivery in United States, on Thursday 3 Feb 2022
Plx-4032
CAS:1029872-54-5
PLX-4032 is a small-molecule B-Raf inhibitor for the potential treatment of malignant melanoma.
Formula:
C23H18ClF2N3O3S
Purity:
99.94%
Color and Shape:
solid
Molecular weight:
489.92
Estimated delivery in United States, on Thursday 3 Feb 2022
Chrysoeriol
CAS:491-71-4
Chrysoeriol has antioxidant, antiinflammatory, antitumor, antimicrobial, antiviral, and free radical scavenging activities, it also shows …
Formula:
C16H12O6
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
300.3
Estimated delivery in United States, on Thursday 3 Feb 2022
BRAF inhibitor
CAS:918505-61-0
BRAF inhibitor is an inhibitor of B-Raf extracted from patent WO/2011103196 A1 (Compound P-0850).
Formula:
C22H18F2N4O3S
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
456.46
Estimated delivery in United States, on Thursday 3 Feb 2022
SGX523
CAS:1022150-57-7
SGX-523 is a selective Met inhibitor (IC50: 4 nM), no inhibitory to Abl, BRAFV599E, p38, …
Formula:
C18H13N7S
Purity:
99.00%
Color and Shape:
solid
Molecular weight:
359.41
Estimated delivery in United States, on Thursday 3 Feb 2022
PD 169316
CAS:152121-53-4
PD 169316 is a potent, cell-permeable and selective p38 MAP kinase inhibitor.
Formula:
C20H13FN4O2
Purity:
98.83%
Color and Shape:
solid
Molecular weight:
360.34
Estimated delivery in United States, on Thursday 3 Feb 2022
PERK-IN-2
CAS:1337531-83-5
PERK-IN-2 is a potent inhibitor of PERK(IC50 of 0.2 nM).
Formula:
C23H18F3N5O
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
437.42
Estimated delivery in United States, on Thursday 3 Feb 2022
Prunetin
CAS:552-59-0
1. Prunetin significantly reduces serum levels of inflammatory cytokines and mortality in mice challenged with …
Formula:
C16H12O5
Purity:
98.00%
Color and Shape:
Creamy White Crystalline Powder
Molecular weight:
284.26
Estimated delivery in United States, on Thursday 3 Feb 2022
Licochalcone D
CAS:144506-15-0
Licochalcone D may be a potential drug for human melanoma treatment by inhibiting proliferation, inducing …
Formula:
C21H22O5
Purity:
98%
Color and Shape:
solid
Molecular weight:
354.4
Estimated delivery in United States, on Thursday 3 Feb 2022
KRAS inhibitor-7
CAS:2022986-68-9
KRAS inhibitor-7 is a potent KRAS G12C inhibitor.
Formula:
C26H27ClF2N6O2
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
528.98
Estimated delivery in United States, on Thursday 3 Feb 2022
KRas G12C inhibitor 4
CAS:2206736-07-2
KRas G12C inhibitor 4 is a compound that inhibits KRas G12C.
Formula:
C33H38ClN7O2
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
600.15
Estimated delivery in United States, on Thursday 3 Feb 2022
Sodium lauryl sulfoacetate
CAS:1847-58-1
Sodium houttuyfonate is anti-pseudomonas agents, inhibits virulence-related motility of Pseudomonas.
Formula:
C14H27NaO5S
Purity:
97.0%
Color and Shape:
solid
Molecular weight:
330.4
Estimated delivery in United States, on Thursday 3 Feb 2022
BI-2852
CAS:2375482-51-0
BI-2852 is a KRAS inhibitor for the switch I/II pocket (SI/II-pocket) with nanomolar affinity. BI-2852 …
Formula:
C31H28N6O2
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
516.59
Estimated delivery in United States, on Thursday 3 Feb 2022
AZ304
CAS:942507-42-8
AZ304 is an ATP-competitive dual BRAF kinase inhibitor, potently inhibits BRAF (WT), BRAF (V600E), and …
Formula:
C27H25N5O2
Purity:
99.83%
Color and Shape:
Solid
Molecular weight:
451.52
Estimated delivery in United States, on Thursday 3 Feb 2022
Cobimetinib
CAS:934660-93-2
Cobimetinib is a selective inhibitor of mitogen-activated protein kinase kinase (MEK) (IC50: 0.9 nM). Cobimetinib …
Formula:
C21H21F3IN3O2
Purity:
98.93%
Color and Shape:
solid
Molecular weight:
531.32
Estimated delivery in United States, on Thursday 3 Feb 2022
Sauchinone
CAS:177931-17-8
1. Sauchinone is a useful adjunctive treatment for bacterial infection. 2. Sauchinone, an active lignan …
Formula:
C20H20O6
Purity:
100.00%
Color and Shape:
solid
Molecular weight:
356.37
Estimated delivery in United States, on Thursday 3 Feb 2022
AZ7550 hydrochloride (1421373-99-0 free base)
CAS:2309762-40-9
AZ7550 hydrochloride, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).
Formula:
C27H32ClN7O2
Molecular weight:
522.04
Estimated delivery in United States, on Thursday 3 Feb 2022
MK-2 Inhibitor III
CAS:1186648-22-5
MK-2 Inhibitor III is an orally active, selective, and ATP-competitive inhibitor of MAPKAP-K2 (MK-2) (IC50 …
Formula:
C21H18N4O2
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
358.39
Estimated delivery in United States, on Thursday 3 Feb 2022
Encorafenib
CAS:1269440-17-6
LGX818 is an orally available mutated BRaf V600E inhibitor(IC50=0.3 nM) with potential antineoplastic activity.
Formula:
C22H27ClFN7O4S
Purity:
99.56%
Color and Shape:
solid
Molecular weight:
540.01
Estimated delivery in United States, on Thursday 3 Feb 2022
AZD-0364
CAS:2097416-76-5
AZD-0364 is a potent and selective ERK2 inhibitor extracted from patent WO2017080979A1 (example 18; IC50: …
Formula:
C24H24F2N8O2
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
494.5
Estimated delivery in United States, on Thursday 3 Feb 2022
p38 MAPK-IN-1
CAS:1006378-90-0
p38 MAPK-IN-1 displays sustained levels, low clearance, and good bioavailability. p38 MAPK-IN-1 is a novel …
Formula:
C21H15F2N2O
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
349.35
Estimated delivery in United States, on Thursday 3 Feb 2022
