p38 MAPK
p38 MAPKs are a subgroup of MAPKs that respond to stress signals and are involved in the regulation of inflammation, cell differentiation, apoptosis, and autophagy. p38 MAPK signaling is crucial in immune responses and is implicated in various diseases, including chronic inflammatory conditions, cancer, and neurodegenerative disorders. At CymitQuimica, we provide a comprehensive range of p38 MAPK inhibitors and modulators to support your research in inflammation, stress response, and therapeutic development.
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Licarin A
CAS:51020-86-1
Licarin A is a natural anti-inflammatory lignan that inhibits PKCα/βII and p38 MAPK pathways, thereby …
Formula:
C20H22O4
Color and Shape:
Solid
Molecular weight:
326.39
Ref: TM-T20728
| 1mg | 89.00 € | ||
| 5mg | 206.00 € | ||
| 10mg | 304.00 € | ||
| 25mg | 503.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
OVA-E1 peptide TFA
CAS:1262750-80-0
OVA-E1 peptide TFA activates the p38 and JNK cascades similarly in mutant and wild-type thymocytes.
Formula:
C49H77F3N10O16
Purity:
98%
Color and Shape:
Solid
Molecular weight:
1119.19
Ref: TM-T38665
| 1mg | 152.00 € | ||
| 5mg | 415.00 € | ||
| 10mg | 622.00 € | ||
| 25mg | 1,119.00 € | ||
| 50mg | 1,679.00 € | ||
| 100mg | 2,520.00 € | ||
| 200mg | 3,780.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
Akt/NF-κB/MAPK-IN-1
Akt/NF-κB/MAPK-IN-1 (compound 2m) serves as a potent, orally active inhibitor targeting NO with an IC50 …
Formula:
C38H56N2O4
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
604.86
Ref: TM-T78838
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 22 Apr 2025
Ro-3201195
CAS:249937-52-8
Ro-3201195 is a novel orally available p38 MAPK inhibitor with high selectivity.
Formula:
C19H18FN3O4
Purity:
100%
Color and Shape:
Liquid
Molecular weight:
371.36
Ref: TM-T68134
| 1mg | 128.00 € | ||
| 5mg | 304.00 € | ||
| 10mg | 457.00 € | ||
| 25mg | 747.00 € | ||
| 50mg | 1,026.00 € | ||
| 100mg | 1,406.00 € | ||
| 500mg | 2,812.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
SJFα
CAS:2254609-27-1
SJFα (SJF alpha) degrades p38α and p38δ and can be used in cancer research.
Formula:
C59H67F2N7O11S
Purity:
95.25%
Color and Shape:
Solid
Molecular weight:
1120.27
Ref: TM-T18681
| 1mg | 96.00 € | ||
| 5mg | 202.00 € | ||
| 10mg | 376.00 € | ||
| 25mg | 802.00 € | ||
| 50mg | 1,415.00 € | ||
| 1mL*10mM (DMSO) | 474.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
Scio-323
CAS:309913-51-7
Scio-323是一种可口服的 p38丝裂原活化蛋白(MAPK)激酶抑制剂。
Formula:
C27H30FN3O4
Purity:
100.00%
Color and Shape:
Liquid
Molecular weight:
479.54
Ref: TM-T68139
| 1mg | 115.00 € | ||
| 5mg | 245.00 € | ||
| 10mg | 363.00 € | ||
| 25mg | 562.00 € | ||
| 50mg | 775.00 € | ||
| 100mg | 1,035.00 € | ||
| 200mg | 1,406.00 € | ||
| 1mL*10mM (DMSO) | 294.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
Talmapimod hydrochloride
CAS:309915-12-6
Talmapimod hydrochloride: selective p38α inhibitor, 9 nM IC50, 10x less effective on p38β, >2000-fold selective …
Formula:
C27H31Cl2FN4O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
549.46
Ref: TM-T12871L
| 25mg | To inquire | ||
| 50mg | To inquire | ||
| 100mg | To inquire |
Estimated delivery in United States, on Tuesday 22 Apr 2025
WYE-687
CAS:1062161-90-3
WYE-687 is a selective mTOR inhibitor (IC50: 7 nM), over 100x more selective for mTOR …
Formula:
C28H32N8O3
Purity:
98.98%
Color and Shape:
Solid
Molecular weight:
528.61
Ref: TM-T6732
| 5mg | 39.00 € | ||
| 10mg | 59.00 € | ||
| 25mg | 113.00 € | ||
| 50mg | To inquire | ||
| 100mg | To inquire | ||
| 1mL*10mM (DMSO) | 50.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
SSK1
CAS:2629250-69-5
SSK1 is a senescent cell-killing and β-galactosidase-targeting precursor compound that activates phosphorylation levels of p38 …
Formula:
C31H34F2N4O18
Purity:
98.97% - 99.83%
Color and Shape:
Solid
Molecular weight:
788.61
Ref: TM-T37450
| 1mg | 205.00 € | ||
| 5mg | 510.00 € | ||
| 10mg | 737.00 € | ||
| 25mg | 1,130.00 € | ||
| 50mg | 1,510.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
R1487 Hydrochloride
CAS:449808-64-4
R1487 Hydrochloride (R1487 (Hydrochloride)) is an orally bioavailable and highly selective inhibitors of p38α.
Formula:
C19H19ClF2N4O3
Purity:
99.42%
Color and Shape:
Solid
Molecular weight:
424.83
Ref: TM-T7162
| 2mg | 72.00 € | ||
| 5mg | 105.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
SB 203580 hydrochloride
CAS:869185-85-3
SB 203580 hydrochloride (Adezmapimod hydrochloride) is a p38 MAPK inhibitor that induces mitochondrial autophagy and …
Formula:
C21H17ClFN3OS
Purity:
97.79%
Color and Shape:
Solid
Molecular weight:
413.9
Ref: TM-T21675
| 5mg | 43.00 € | ||
| 10mg | 59.00 € | ||
| 25mg | 93.00 € | ||
| 50mg | 120.00 € | ||
| 100mg | 172.00 € | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
Adezmapimod
CAS:152121-47-6
Adezmapimod (SB 203580) is a p38 MAPK inhibitor (IC50=0.3-0.5 μM) that is selective and ATP-competitive.
Formula:
C21H16FN3OS
Purity:
99.42% - 99.87%
Color and Shape:
White Solid
Molecular weight:
377.43
Ref: TM-T1764
| 5mg | 35.00 € | ||
| 10mg | 51.00 € | ||
| 50mg | 70.00 € | ||
| 100mg | 99.00 € | ||
| 200mg | 170.00 € | ||
| 500mg | 278.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
Neflamapimod
CAS:209410-46-8
Neflamapimod (VX-745) , a specific and effective inhibitor of p38α(IC50=10 nM), is 22-fold greater specificity …
Formula:
C19H9Cl2F2N3OS
Purity:
99.02% - ≥95%
Color and Shape:
Solid
Molecular weight:
436.26
Ref: TM-T6089
| 5mg | 50.00 € | ||
| 10mg | 77.00 € | ||
| 25mg | 126.00 € | ||
| 50mg | 207.00 € | ||
| 100mg | 306.00 € | ||
| 200mg | 457.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
Sertaconazole nitrate
CAS:99592-39-9
Sertaconazole nitrate, a broad-spectrum topical antifungal, treats skin and mucosal infections.
Formula:
C20H15Cl3N2OS·HNO3
Purity:
98.66%
Color and Shape:
Solid
Molecular weight:
500.78
Ref: TM-T6665
| 10mg | 46.00 € | ||
| 25mg | 52.00 € | ||
| 50mg | 72.00 € | ||
| 100mg | 97.00 € | ||
| 200mg | 180.00 € | ||
| 1mL*10mM (DMSO) | 47.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
ASK1-IN-1
CAS:2411382-24-4
ASK1-IN-1 inhibits apoptosis kinase 1, crucial in cell stress responses, with 21 nM IC50.
Formula:
C19H19N9O2
Purity:
99.52%
Color and Shape:
Solid
Molecular weight:
405.41
Ref: TM-T9697
| 1mg | 90.00 € | ||
| 5mg | 215.00 € | ||
| 10mg | 321.00 € | ||
| 25mg | 582.00 € | ||
| 50mg | 873.00 € | ||
| 100mg | 1,216.00 € | ||
| 1mL*10mM (DMSO) | 236.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
SB 202190
CAS:152121-30-7
SB 202190 (FHPI) is a p38 MAPK inhibitor that inhibits p38α and p38β2 (IC50=50/100 nM) …
Formula:
C20H14FN3O
Purity:
98% - 99.84%
Color and Shape:
Pale Yellow
Molecular weight:
331.34
Ref: TM-T2301
| 25mg | 42.00 € | ||
| 50mg | 55.00 € | ||
| 100mg | 95.00 € | ||
| 200mg | 160.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
CK1-IN-1
CAS:1784751-20-7
CK1-IN-1, a CK1 inhibitor with IC50: 15nM CK1δ, 16nM CK1ε, 73nM p38σ; patent WO2015119579A1.
Formula:
C24H15F2N3
Purity:
98.79%
Color and Shape:
Solid
Molecular weight:
383.39
Ref: TM-T5393
| 1mg | 49.00 € | ||
| 2mg | 65.00 € | ||
| 5mg | 97.00 € | ||
| 10mg | 160.00 € | ||
| 25mg | 305.00 € | ||
| 50mg | 472.00 € | ||
| 100mg | 707.00 € | ||
| 1mL*10mM (DMSO) | 106.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
2-Aminooctadecane-1,3,4-Triol
CAS:13552-11-9
2-Aminooctadecane-1,3,4-Triol (Phytosphingosine) is a natural product.
Formula:
C18H39NO3
Purity:
≥98%
Color and Shape:
Solid
Molecular weight:
317.51
Ref: TM-TN6814
| 1mg | 185.00 € | ||
| 5mg | 415.00 € | ||
| 10mg | 613.00 € | ||
| 25mg | 938.00 € | ||
| 50mg | 1,311.00 € | ||
| 100mg | 1,768.00 € | ||
| 500mg | 3,535.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
Gypenoside L
CAS:94987-09-4
Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through …
Formula:
C42H72O14
Purity:
99.42% - 99.65%
Color and Shape:
Solid
Molecular weight:
801.01
Ref: TM-TN1721
| 1mg | 126.00 € | ||
| 5mg | 296.00 € | ||
| 10mg | 378.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
UM-164
CAS:903564-48-7
UM-164 (DAS-DFGO-II), a highly potent c-Src inhibitor with a dissociation constant (Kd) of 2.7 nM, …
Formula:
C30H31F3N8O3S
Purity:
98.72% - 99.52%
Color and Shape:
Solid
Molecular weight:
640.68
Ref: TM-T4597
| 1mg | 35.00 € | ||
| 2mg | 50.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 119.00 € | ||
| 25mg | 188.00 € | ||
| 50mg | 283.00 € | ||
| 100mg | 418.00 € |
Estimated delivery in United States, on Monday 28 Apr 2025
