p38 MAPK
p38 MAPKs are a subgroup of MAPKs that respond to stress signals and are involved in the regulation of inflammation, cell differentiation, apoptosis, and autophagy. p38 MAPK signaling is crucial in immune responses and is implicated in various diseases, including chronic inflammatory conditions, cancer, and neurodegenerative disorders. At CymitQuimica, we provide a comprehensive range of p38 MAPK inhibitors and modulators to support your research in inflammation, stress response, and therapeutic development.
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FERULIC ACID METHYL ESTER
CAS:2309-07-1
FERULIC ACID METHYL ESTER (Methyl ferulate) is a hydroxycinnamic acid that is abundant in plants. …
Formula:
C11H12O4
Purity:
99.66% - 99.87%
Color and Shape:
Solid
Molecular weight:
208.21
Ref: TM-TL0004
| 100mg | 34.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
BMS-582949 hydrochloride
CAS:912806-16-7
The BMS-582949 hydrochloride (BMS-582949 HCl) is a highly specific p38α MAPK inhibitor (IC50: 13 nM).
Formula:
C22H27ClN6O2
Purity:
97.57% - 98.75%
Color and Shape:
Solid
Molecular weight:
442.95
Ref: TM-T3462
| 1mg | 51.00 € | ||
| 2mg | 73.00 € | ||
| 5mg | 105.00 € | ||
| 10mg | 167.00 € | ||
| 25mg | 271.00 € | ||
| 50mg | 435.00 € | ||
| 100mg | 647.00 € | ||
| 500mg | 1,348.00 € | ||
| 1mL*10mM (DMSO) | 116.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
R1487
CAS:449811-92-1
R1487 is an orally bioavailable and highly selective p38α mitogen-activated protein kinase inhibitor.
Formula:
C19H18F2N4O3
Purity:
≥95%
Color and Shape:
Solid
Molecular weight:
388.37
Ref: TM-T7667
| 1mg | 128.00 € | ||
| 5mg | 277.00 € | ||
| 10mg | 421.00 € | ||
| 25mg | 694.00 € | ||
| 50mg | 979.00 € | ||
| 100mg | 1,324.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
SR-318
CAS:2413286-32-3
SR-318 inhibits TNF-α (IC50=283 nM), selectively targets p38 MAPK: IC50 of 5nM (p38α), 32nM (p38β), …
Formula:
C27H33N5O2
Purity:
99.53%
Color and Shape:
Solid
Molecular weight:
459.58
Ref: TM-T12997
| 2mg | 37.00 € | ||
| 5mg | 57.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 171.00 € | ||
| 50mg | 266.00 € | ||
| 100mg | 382.00 € | ||
| 200mg | 548.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Afatinib Dimaleate
CAS:850140-73-7
Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the EGFR …
Formula:
C32H33ClFN5O11
Purity:
100% - 99.66%
Color and Shape:
Solid
Molecular weight:
718.08
Ref: TM-T1773
| 1g | 460.00 € | ||
| 5mg | 40.00 € | ||
| 10mg | 58.00 € | ||
| 25mg | 85.00 € | ||
| 50mg | 105.00 € | ||
| 100mg | 138.00 € | ||
| 200mg | 184.00 € | ||
| 500mg | 308.00 € | ||
| 1mL*10mM (DMSO) | 66.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
TA-02
CAS:1784751-19-4
TA-02 is a p38 MAPK inhibitor with IC50 of 20 nM.TA-02 especially inhibits TGFBR-2.
Formula:
C20H13F2N3
Purity:
99.35% - 99.79%
Color and Shape:
Solid
Molecular weight:
333.33
Ref: TM-T4646
| 5mg | 39.00 € | ||
| 10mg | 57.00 € | ||
| 25mg | 103.00 € | ||
| 50mg | 157.00 € | ||
| 100mg | 239.00 € | ||
| 500mg | To inquire | ||
| 1mL*10mM (DMSO) | 43.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
TA-01
CAS:1784751-18-3
TA-01 is a potent CK1 and p38 MAPK inhibitor, with IC50s of 6.4 nM, 6.8 …
Formula:
C20H12F3N3
Purity:
98.77% - 99.94%
Color and Shape:
Solid
Molecular weight:
351.32
Ref: TM-T4645
| 2mg | 35.00 € | ||
| 5mg | 51.00 € | ||
| 10mg | 82.00 € | ||
| 25mg | 150.00 € | ||
| 50mg | 227.00 € | ||
| 100mg | 318.00 € | ||
| 200mg | 447.00 € | ||
| 1mL*10mM (DMSO) | 69.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Ralimetinib dimesylate
CAS:862507-23-1
Ralimetinib dimesylate (LY2228820 dimesylate) is a orally available, p38 MAPK inhibitor with potential anti-inflammatory and …
Formula:
C24H29FN6·2CH4O3S
Purity:
98% - 99.38%
Color and Shape:
Solid
Molecular weight:
612.74
Ref: TM-T6047
| 1mg | 41.00 € | ||
| 5mg | 83.00 € | ||
| 10mg | 128.00 € | ||
| 25mg | 236.00 € | ||
| 50mg | 361.00 € | ||
| 100mg | 462.00 € | ||
| 1mL*10mM (DMSO) | 99.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Skatole
CAS:83-34-1
Skatole (3-Methyl-1H-indole), produced by bacteria, regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors …
Formula:
C9H9N
Purity:
99.74%
Color and Shape:
Leaves From Petroleum Ether; White-Brown Scales Solid
Molecular weight:
131.17
Ref: TM-T5281
| 1g | 34.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
MW-150
CAS:1628502-91-9
MW-150 (MW01-18-150SRM) is a unique protein kinase inhibitor, is a selective, CNS penetrant, and orally …
Formula:
C24H23N5
Purity:
99.27% - ≥95%
Color and Shape:
Solid
Molecular weight:
381.47
Ref: TM-T5494
| 1mg | 39.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 151.00 € | ||
| 25mg | 302.00 € | ||
| 50mg | 449.00 € | ||
| 100mg | 647.00 € | ||
| 500mg | 1,379.00 € | ||
| 1mL*10mM (DMSO) | 113.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Isoliquiritin apioside
CAS:120926-46-7
Isoliquiritin apioside, from Glycyrrhizae radix, inhibits MMP9, MAPK, NF-κB, reduces cancer cell invasion, angiogenesis, and …
Formula:
C26H30O13
Purity:
98.84% - 99.27%
Color and Shape:
Solid
Molecular weight:
550.51
Ref: TM-T3860
| 1mg | 53.00 € | ||
| 5mg | 111.00 € | ||
| 10mg | 169.00 € | ||
| 25mg | 280.00 € | ||
| 50mg | 428.00 € | ||
| 100mg | 616.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Esculin
CAS:531-75-9
Esculin (Aesculin) is a glucoside found in horse chestnuts.
Formula:
C15H16O9
Purity:
99.67%
Color and Shape:
Cream Powder
Molecular weight:
340.28
Ref: TM-T2885
| 500mg | 50.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Doramapimod
CAS:285983-48-4
Doramapimod (BIRB 796) is a highly potent inhibitor of p38 MAPK (Kd: 0.1 nM), but …
Formula:
C31H37N5O3
Purity:
97.73% - 99.65%
Color and Shape:
Solid
Molecular weight:
527.66
Ref: TM-T6277
| 1g | 552.00 € | ||
| 5mg | 36.00 € | ||
| 10mg | 54.00 € | ||
| 25mg | 78.00 € | ||
| 50mg | 90.00 € | ||
| 100mg | 124.00 € | ||
| 200mg | 220.00 € | ||
| 500mg | 371.00 € | ||
| 1mL*10mM (DMSO) | 44.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Bakuchiol
CAS:10309-37-2
Bakuchiol: anti-tumor, anti-helminthic, DNA polymerase1 inhibitor, cytotoxic, and anti-bacterial, may prevent dental caries.
Formula:
C18H24O
Purity:
98.69% - 99.47%
Color and Shape:
Brownish Yellow Liquid Viscous
Molecular weight:
256.38
Ref: TM-T3400
| 20mg | 86.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Aurantiamide
CAS:58115-31-4
Aurantiamide inhibits cancer, inflammation, pain, and neuroinflammation by blocking autophagy and NF-κB, JNK, p38 pathways.
Formula:
C25H26N2O3
Purity:
98.88%
Color and Shape:
Solid
Molecular weight:
402.49
Ref: TM-T5814
| 1mg | 134.00 € | ||
| 5mg | 322.00 € | ||
| 10mg | 478.00 € | ||
| 25mg | 763.00 € | ||
| 50mg | 1,011.00 € | ||
| 100mg | 1,382.00 € | ||
| 1mL*10mM (DMSO) | 466.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
PH-797804
CAS:586379-66-0
PH-797804 is a pyridinone inhibitor of p38α (IC50: 26 nM, in a cell-free assay); 4-fold …
Formula:
C22H19BrF2N2O3
Purity:
97.79% - 98.96%
Color and Shape:
Solid
Molecular weight:
477.3
Ref: TM-T1974
| 1mg | 45.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 143.00 € | ||
| 25mg | 252.00 € | ||
| 50mg | 402.00 € | ||
| 100mg | 621.00 € | ||
| 500mg | 1,304.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Dehydrocorydaline
CAS:30045-16-0
1.
Formula:
C22H24NO4
Purity:
99.84%
Color and Shape:
Solid
Molecular weight:
366.43
Ref: TM-T5S2358
| 1mg | 56.00 € | ||
| 2mg | 80.00 € | ||
| 5mg | 109.00 € | ||
| 10mg | 157.00 € | ||
| 25mg | 257.00 € | ||
| 50mg | 369.00 € | ||
| 100mg | 549.00 € | ||
| 1mL*10mM (DMSO) | 123.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Bisabolangelone
CAS:30557-81-4
Bisabolangelone: anti-tumor, anti-inflammatory, anti-microbial, antioxidant, blocks MAPK/NF-κB in dendritic cells.
Formula:
C15H20O3
Purity:
98.91%
Color and Shape:
Solid
Molecular weight:
248.32
Ref: TM-TN1445
| 1mg | 52.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 158.00 € | ||
| 25mg | 258.00 € | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 94.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
SM-7368
CAS:380623-76-7
The NF-κB Activation Inhibitor III, controls the biological activity of NF-κB. It is primarily used …
Formula:
C10H5ClN4O5S
Purity:
99.64% - 99.64%
Color and Shape:
Solid
Molecular weight:
328.69
Ref: TM-T22115
| 5mg | 45.00 € | ||
| 10mg | 72.00 € | ||
| 25mg | 130.00 € | ||
| 50mg | 182.00 € | ||
| 100mg | 272.00 € | ||
| 200mg | 397.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
AMG 900
CAS:945595-80-2
AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with …
Formula:
C28H21N7OS
Purity:
98.35% - 98.9%
Color and Shape:
Solid
Molecular weight:
503.58
Ref: TM-T6380
| 1mg | 52.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 163.00 € | ||
| 25mg | 295.00 € | ||
| 50mg | 457.00 € | ||
| 100mg | 670.00 € | ||
| 500mg | 1,384.00 € | ||
| 1mL*10mM (DMSO) | 103.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
