p38 MAPK
p38 MAPKs are a subgroup of MAPKs that respond to stress signals and are involved in the regulation of inflammation, cell differentiation, apoptosis, and autophagy. p38 MAPK signaling is crucial in immune responses and is implicated in various diseases, including chronic inflammatory conditions, cancer, and neurodegenerative disorders. At CymitQuimica, we provide a comprehensive range of p38 MAPK inhibitors and modulators to support your research in inflammation, stress response, and therapeutic development.
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Sertaconazole nitrate
CAS:99592-39-9
Sertaconazole nitrate, a broad-spectrum topical antifungal, treats skin and mucosal infections.
Formula:
C20H15Cl3N2OS·HNO3
Purity:
98.66%
Color and Shape:
Solid
Molecular weight:
500.78
Ref: TM-T6665
| 10mg | 45.00 € | ||
| 25mg | 52.00 € | ||
| 50mg | 72.00 € | ||
| 100mg | 95.00 € | ||
| 200mg | 176.00 € | ||
| 1mL*10mM (DMSO) | 47.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
ASK1-IN-1
CAS:2411382-24-4
ASK1-IN-1 inhibits apoptosis kinase 1, crucial in cell stress responses, with 21 nM IC50.
Formula:
C19H19N9O2
Purity:
99.52%
Color and Shape:
Solid
Molecular weight:
405.41
Ref: TM-T9697
| 1mg | 90.00 € | ||
| 5mg | 212.00 € | ||
| 10mg | 317.00 € | ||
| 25mg | 574.00 € | ||
| 50mg | 862.00 € | ||
| 100mg | 1,201.00 € | ||
| 1mL*10mM (DMSO) | 234.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
SB 202190
CAS:152121-30-7
SB 202190 (FHPI) is a p38 MAPK inhibitor that inhibits p38α and p38β2 (IC50=50/100 nM) …
Formula:
C20H14FN3O
Purity:
98% - 99.84%
Color and Shape:
Pale Yellow
Molecular weight:
331.34
Ref: TM-T2301
| 25mg | 42.00 € | ||
| 50mg | 55.00 € | ||
| 100mg | 95.00 € | ||
| 200mg | 159.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
CK1-IN-1
CAS:1784751-20-7
CK1-IN-1, a CK1 inhibitor with IC50: 15nM CK1δ, 16nM CK1ε, 73nM p38σ; patent WO2015119579A1.
Formula:
C24H15F2N3
Purity:
98.79%
Color and Shape:
Solid
Molecular weight:
383.39
Ref: TM-T5393
| 1mg | 50.00 € | ||
| 2mg | 65.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 159.00 € | ||
| 25mg | 304.00 € | ||
| 50mg | 468.00 € | ||
| 100mg | 703.00 € | ||
| 1mL*10mM (DMSO) | 106.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
2-Aminooctadecane-1,3,4-Triol
CAS:13552-11-9
2-Aminooctadecane-1,3,4-Triol (Phytosphingosine) is a natural product.
Formula:
C18H39NO3
Purity:
≥98%
Color and Shape:
Solid
Molecular weight:
317.51
Ref: TM-TN6814
| 1mg | 185.00 € | ||
| 5mg | 415.00 € | ||
| 10mg | 613.00 € | ||
| 25mg | 937.00 € | ||
| 50mg | 1,309.00 € | ||
| 100mg | 1,764.00 € | ||
| 500mg | 3,455.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Gypenoside L
CAS:94987-09-4
Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through …
Formula:
C42H72O14
Purity:
99.42% - 99.65%
Color and Shape:
Solid
Molecular weight:
801.01
Ref: TM-TN1721
| 1mg | 124.00 € | ||
| 5mg | 290.00 € | ||
| 10mg | 369.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
UM-164
CAS:903564-48-7
UM-164 (DAS-DFGO-II), a highly potent c-Src inhibitor with a dissociation constant (Kd) of 2.7 nM, …
Formula:
C30H31F3N8O3S
Purity:
98.72% - 99.52%
Color and Shape:
Solid
Molecular weight:
640.68
Ref: TM-T4597
| 1mg | 35.00 € | ||
| 2mg | 51.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 185.00 € | ||
| 50mg | 277.00 € | ||
| 100mg | 409.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Adezmapimod
CAS:152121-47-6
Adezmapimod (SB 203580) is a p38 MAPK inhibitor (IC50=0.3-0.5 μM) that is selective and ATP-competitive.
Formula:
C21H16FN3OS
Purity:
99.42% - 99.87%
Color and Shape:
White Solid
Molecular weight:
377.43
Ref: TM-T1764
| 5mg | 35.00 € | ||
| 10mg | 51.00 € | ||
| 50mg | 69.00 € | ||
| 100mg | 97.00 € | ||
| 200mg | 167.00 € | ||
| 500mg | 272.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
5,6,7-TRIMETHOXYFLAVONE
CAS:973-67-1
5,6,7-Trimethoxyflavone, a natural product extracted from Japanese Callicarpa, acts as a p38-α MAPK inhibitor and …
Formula:
C18H16O5
Purity:
99.05% - 99.11%
Color and Shape:
Solid
Molecular weight:
312.32
Ref: TM-T7051
| 1mg | 35.00 € | ||
| 5mg | 68.00 € | ||
| 10mg | 93.00 € | ||
| 25mg | 181.00 € | ||
| 50mg | 272.00 € | ||
| 100mg | 392.00 € | ||
| 1mL*10mM (DMSO) | 45.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
SD 0006
CAS:271576-80-8
SD 0006 (SD-06) is a MAPK p38 alpha inhibitor( IC50 : 110 nM) for the …
Formula:
C20H20ClN5O2
Purity:
98.32%
Color and Shape:
Solid
Molecular weight:
397.86
Ref: TM-T7276
| 2mg | 37.00 € | ||
| 5mg | 57.00 € | ||
| 10mg | 89.00 € | ||
| 25mg | 142.00 € | ||
| 50mg | 220.00 € | ||
| 100mg | 328.00 € | ||
| 200mg | 459.00 € | ||
| 1mL*10mM (DMSO) | 63.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Nitidine chloride
CAS:13063-04-2
1.
Formula:
C21H18ClNO4
Purity:
96.59% - 98.91%
Color and Shape:
Solid
Molecular weight:
383.82
Ref: TM-T5S0761
| 1mg | 35.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 109.00 € | ||
| 25mg | 172.00 € | ||
| 50mg | 298.00 € | ||
| 100mg | 441.00 € | ||
| 500mg | 916.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
SB 239063
CAS:193551-21-2
SB 239063 (SB239063) is a potent and selective p38 MAPKα/β inhibitor with IC50 of 44 …
Formula:
C20H21FN4O2
Purity:
99.42% - 99.81%
Color and Shape:
Solid
Molecular weight:
368.4
Ref: TM-T6976
| 1mg | 50.00 € | ||
| 2mg | 63.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 156.00 € | ||
| 25mg | 330.00 € | ||
| 50mg | 495.00 € | ||
| 100mg | 712.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Rotundic acid
CAS:20137-37-5
Rotundic acid fights various cancers: HepG2, A375, NCI-H446, MCF-7, and HT-29.
Formula:
C30H48O5
Purity:
96.91% - 99.28%
Color and Shape:
Solid
Molecular weight:
488.7
Ref: TM-T5S0506
| 2mg | 35.00 € | ||
| 5mg | 51.00 € | ||
| 10mg | 79.00 € | ||
| 25mg | 141.00 € | ||
| 50mg | 222.00 € | ||
| 100mg | 330.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Kaempferol-3-O-glucorhamnoside
CAS:40437-72-7
Kaempferol-3-O-glucorhamnoside (Kaempferol 3-glucorhamnoside), a flavonoid derived from plant Thesium chinense Turcz, inhibits inflammatory responses via …
Formula:
C27H30O15
Purity:
96.96% - 98.17%
Color and Shape:
Solid
Molecular weight:
594.5
Ref: TM-T5S0089
| 1mg | 77.00 € | ||
| 5mg | 161.00 € | ||
| 10mg | 228.00 € | ||
| 25mg | 373.00 € | ||
| 50mg | 560.00 € | ||
| 100mg | 814.00 € | ||
| 1mL*10mM (DMSO) | 205.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Sertaconazole
CAS:99592-32-2
Sertaconazole is a broad-spectrum antifungal.
Formula:
C20H15Cl3N2OS
Purity:
95.00%
Color and Shape:
Solid
Molecular weight:
437.77
Ref: TM-T50005
| 5mg | 57.00 € | ||
| 10mg | 81.00 € | ||
| 25mg | 123.00 € | ||
| 50mg | 179.00 € | ||
| 100mg | 267.00 € | ||
| 200mg | 403.00 € | ||
| 1mL*10mM (DMSO) | 83.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Paris saponin VII
CAS:68124-04-9
Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.
Formula:
C51H82O21
Purity:
99.51% - 99.63%
Color and Shape:
Solid
Molecular weight:
1031.18
Ref: TM-T4085
| 1mg | 50.00 € | ||
| 5mg | 106.00 € | ||
| 10mg | 177.00 € | ||
| 25mg | 297.00 € | ||
| 50mg | 443.00 € | ||
| 100mg | 633.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Talmapimod
CAS:309913-83-5
Talmapimod (SCIO-469): Oral ATP-competitive p38α inhibitor, IC50 = 9 nM (p38α), 90 nM (p38β), >2000-fold …
Formula:
C27H30ClFN4O3
Purity:
100% - 98%
Color and Shape:
Solid
Molecular weight:
513
Ref: TM-T12871
| 1mg | 52.00 € | ||
| 2mg | 76.00 € | ||
| 5mg | 113.00 € | ||
| 10mg | 174.00 € | ||
| 25mg | 369.00 € | ||
| 50mg | 547.00 € | ||
| 100mg | 786.00 € | ||
| 1mL*10mM (DMSO) | 130.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
BMS582949
CAS:623152-17-0
BMS-582949 inhibits p38 MAPK with 13 nM IC50, blocking kinase activity and activation.
Formula:
C22H26N6O2
Purity:
98.43%
Color and Shape:
Solid
Molecular weight:
406.48
Ref: TM-T6789
| 1mg | 86.00 € | ||
| 2mg | 119.00 € | ||
| 5mg | 209.00 € | ||
| 10mg | 296.00 € | ||
| 25mg | 497.00 € | ||
| 50mg | 721.00 € | ||
| 100mg | 1,013.00 € | ||
| 1mL*10mM (DMSO) | 209.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Pexmetinib
CAS:945614-12-0
Pexmetinib (ARRY-614) is an orally bioavailable dual p38 MAPK/Tie-2 inhibitor.Cost-effective and quality-assured.
Formula:
C31H33FN6O3
Purity:
98.41% - 99.66%
Color and Shape:
Solid
Molecular weight:
556.63
Ref: TM-T6934
| 2mg | 58.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 151.00 € | ||
| 25mg | 296.00 € | ||
| 50mg | 501.00 € | ||
| 100mg | 558.00 € | ||
| 1mL*10mM (DMSO) | 119.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Andrograpanin
CAS:82209-74-3
Andrograpanin (19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE) is a bioactive compound from Andrographis paniculata.
Formula:
C20H30O3
Purity:
99.03%
Color and Shape:
Solid
Molecular weight:
318.45
Ref: TM-T9218
| 1mg | 60.00 € | ||
| 5mg | 134.00 € | ||
| 10mg | 184.00 € | ||
| 25mg | To inquire | ||
| 1mL*10mM (DMSO) | 141.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
