Membrane Transporter/Ion Channel
Membrane transporter and ion channel inhibitors are compounds that block the function of proteins responsible for the transport of ions, nutrients, and other molecules across cell membranes. These inhibitors are crucial for studying the regulation of cellular homeostasis, signal transduction, and neurotransmission. Membrane transporter and ion channel inhibitors are also important in developing treatments for disorders such as epilepsy, cardiovascular diseases, and metabolic syndromes. At CymitQuimica, we provide a diverse selection of high-quality membrane transporter and ion channel inhibitors to support your research in physiology, neuroscience, and pharmacology.
Subcategories of "Membrane Transporter/Ion Channel"
- ABC(3 products)
- ATPase(93 products)
- Adiponectin receptor(5 products)
- CFTR(64 products)
- CGRP Receptor(52 products)
- Calcium Channel(496 products)
- Chloride channel(49 products)
- GABA Receptor(336 products)
- Monoamine Transporter(23 products)
- Monocarboxylate transporter(17 products)
- NKCC(2 products)
- NPC1L1(3 products)
- Na-K-Cl cotransporter(8 products)
- OAT(27 products)
- OCT(7 products)
- P-gp(53 products)
- Potassium Channel(277 products)
- Proton pump(39 products)
- SGLT(30 products)
- Sodium Channel(202 products)
- TRP/TRPV Channel(93 products)
Show 13 more subcategories
Found 2290 products of "Membrane Transporter/Ion Channel"
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α-Casozepine
CAS:<p>α-Casozepine,Bioactive peptide from milk α-S1 casein. Binds GABA receptors. Anti-anxiety effects.</p>Formula:C60H94N14O16Color and Shape:SolidMolecular weight:1267.47Ruzinurad
CAS:<p>Ruzinurad (WO2020088641, compound I) is a potent URAT1 inhibitor, exhibiting high selectivity.</p>Formula:C14H12BrNO2SColor and Shape:SolidMolecular weight:338.22AR-C141990 hydrochloride
CAS:<p>AR-C141990 HCl inhibits MCT-1 (pKi 7.6) and MCT-2 (pKi 6.6), and has immunosuppressive effects.</p>Formula:C26H29ClN4O4SColor and Shape:SolidMolecular weight:529.05Venturicidin A
CAS:<p>Venturicidin A is a macrolide antibiotic.</p>Formula:C41H67NO11Purity:98%Color and Shape:SolidMolecular weight:749.97P-gp/BCRP-IN-2
<p>P-gp/BCRP-IN-2 (compound 15), an oxadiazole derivative, functions as a dual inhibitor targeting both the ABC transporter P-glycoprotein (IC50: 1.6 nM) and BCRP</p>Formula:C32H35N3O6Color and Shape:SolidMolecular weight:557.64Chlorpropylate
CAS:Chlorpropylate is an insecticide.Formula:C17H16Cl2O3Purity:98%Color and Shape:SolidMolecular weight:339.21URAT1 inhibitor 11
CAS:<p>URAT1 inhibitor11 (Compound 7) is a potent URAT1 inhibitor, exhibiting an IC50 of 0.18 μM. It effectively reduces uric acid levels in zebrafish with hyperuricemia induced by Potassium oxonate and Xanthinesodium salt.</p>Formula:C20H16F4N2O2Color and Shape:SolidMolecular weight:392.35Camegliptin
CAS:<p>Cameglipti, a dipeptidyl peptidase IV (DPP-4) inhibitor, is used potentially for the treatment of type 2 diabetes.</p>Formula:C20H28FN3O3Color and Shape:SolidMolecular weight:377.45FD 12-9
CAS:FD 12-9, Anti-glioblastoma activity. is a flavonoid dimer, acts as a dual inhibitor of P-gp and BCRP, with EC50s of 285 nM and 0.9 nM, respectively.Formula:C51H47N3O11Purity:98%Color and Shape:SolidMolecular weight:877.93Aglafoline
CAS:Aglafoline inhibits in a concentration-dependent manner the aggregation and ATP release reaction induced in washed rabbit platelets by PAF (platelet-activatingFormula:C28H28O8Color and Shape:SolidMolecular weight:492.52TRPA1 Antagonist 3
CAS:<p>TRPA1 Antagonist 3 is a compound with photoswitchable properties that acts as an agonist on the TRPA1 channel, providing the ability for optical control.</p>Formula:C11H8ClN3Color and Shape:SolidMolecular weight:217.66Cyclocreatine
CAS:<p>Cyclocreatine, a creatine analogue and substrate for creatine kinase, inhibits creatine metabolism and prostate cancer cell proliferation.</p>Formula:C5H9N3O2Purity:99.864%Color and Shape:SolidMolecular weight:143.144-Hydroxytolbutamide
CAS:<p>4-Hydroxytolbutamide is a drug metabolite derived from the metabolism of Tolbutamide by CYP2C8 and CYP2C9 a sulfonylurea hypoglycemic agent.</p>Formula:C12H18N2O4SPurity:98%Color and Shape:White To Off-WhiteMolecular weight:286.35Bafilomycin B1
CAS:Bafilomycin B1, a Streptomyces-derived macrolide, inhibits E. coli ATPase and fights Gram-positive bacteria and fungi.Formula:C44H65NO13Purity:98%Color and Shape:White PowderMolecular weight:815.998Antimalarial agent 41
<p>Antimalarial agent 41 (Compound 17) exhibits antimalarial activity by inhibiting the malaria parasite Plasmodium falciparum, with IC50 values of 40 nM for NF54 strain and 76 nM for K1 strain. This compound acts as an inhibitor of P. falciparum phosphatidylinositol-4-kinase β (PfPI4K) and hERG channels, with IC50 values of 53 nM and 3 μM, respectively. Additionally, Antimalarial agent 41 shows cytotoxicity against CHO cells, with an IC50 of 34 μM. It can improve malaria infections and demonstrates favorable pharmacokinetic properties in mouse models.</p>Formula:C19H18F3N5Molecular weight:373.15143UK-59811 hydrochloride
CAS:<p>UK-59811 hydrochloride, Br-dihydropyridine derivative, blocks Ca V Ab channels in bacteria, IC50: 194 nM.</p>Formula:C22H30BrClN2O5Color and Shape:SolidMolecular weight:517.85Conantokin-T
CAS:<p>Non-competitive NMDA receptor antagonist</p>Formula:C110H175N31O45SPurity:98%Color and Shape:SolidMolecular weight:2683.81Homocarnosine
CAS:<p>Homocarnosine is an endogenous dipeptide in cerebral regions and cerebrospinal fluid.</p>Formula:C10H16N4O3Color and Shape:SolidMolecular weight:240.26APETx2 TFA
<p>APETx2 TFA from sea anemone is a selective ASIC3 inhibitor with a 63 nM IC50, reversing acid and inflammatory pain.</p>Formula:C198H281F3N54O62S6Color and Shape:SolidMolecular weight:4675.02CALP3
CAS:<p>Cell-permeable CaM agonist, binds EF-hand, activates phosphodiesterase without Ca2+, inhibits Ca2+ toxicity, IC50=33μM.</p>Formula:C44H68N10O9Purity:98%Color and Shape:SolidMolecular weight:881.08(S)-PF-03716556
CAS:<p>(S)-PF-03716556 can be used as an acid pump inhibitor for the treatment of disease conditions mediated by acid pump inhibitory activity.</p>Formula:C22H26N4O3Purity:99.8% - 99.91%Color and Shape:SoildMolecular weight:394.47ω-Conotoxin MVIIC
CAS:<p>Peptide neurotoxin; wide spectrum blocker of N, P and Q type calcium channels.</p>Formula:C106H178N40O32S7Purity:98%Color and Shape:White Lyophilised SolidMolecular weight:2749ω-Conotoxin MVIIC TFA
<p>ω-Conotoxin MVIIC TFA is a peptide and neurotoxin blocks P-type and q-type voltage-sensitive neuronal Ca ++ channels (VGCCs) radiolabel immunoprecipitation.</p>Formula:C106H178N40O32S7·C2HF3O2Color and Shape:SolidMolecular weight:2863.27Isotachysterol 3
CAS:<p>Isotachysterol 3 boosts calcium transport in gut and bone mobilization in kidneyless rats.</p>Formula:C27H44OColor and Shape:SolidMolecular weight:384.64Guangxitoxin 1E
CAS:<p>Guangxitoxin 1E acts as a gating modifier since it shifts the voltage-dependence of Kv2.1 K+ currents towards depolarized potentials.</p>Formula:C178H248N44O45S7Purity:98%Color and Shape:SolidMolecular weight:3948.61AP14145 hydrochloride
CAS:<p>AP14145 hydrochloride inhibits KCa2.2 and KCa2.3 channels with 1.1 μM IC50, affecting AERP and antiarrhythmic in AF models.</p>Formula:C18H18ClF3N4OColor and Shape:SolidMolecular weight:398.816-FAM-AEEAC-SHK TFA
<p>6-FAM-AEEAC-SHK TFA, a peptide neurotoxin derived from Stichodactyla helianthus and conjugated with a fluorescent marker, selectively blocks voltage-gated potassium channels (kv1.1 and kv1.2). By prolonging action potentials, it interferes with neural signal conduction, making it valuable in neuroscience research.</p>Formula:C196H295N55O57S7·xCHF3O2Color and Shape:SolidMolecular weight:4558.23 (free acid)17(S)-HETE
CAS:<p>Arachidonic acid and its CYP450 metabolite, 17(S)-HETE, regulate kidney electrolytes; 17(S)-HETE reduces proximal tubule ATPase activity by 70% at 2 μM.</p>Formula:C20H32O3Color and Shape:SolidMolecular weight:320.473Detajmium bitartrate
CAS:<p>Detajmium bitartrate is used as an antiarrhythmic drug.</p>Formula:C31H47N3O9Color and Shape:SolidMolecular weight:605.72Huwentoxin I
CAS:<p>Huwentoxin I (HWTX-I) is a peptide toxin that targets and inhibits both voltage-gated sodium channels and N-type calcium channels.</p>Formula:C161H246N48O44S6Purity:98%Color and Shape:SolidMolecular weight:3750.36Trans (2,3)-Dihydrotetrabenazine
CAS:<p>Trans (2,3)-Dihydrotetrabenazine is a Tetrabenazine metabolite, shows inhibition activity on vesicular monoamine transporter (VMAT2).</p>Formula:C19H29NO3Purity:98%Color and Shape:SolidMolecular weight:319.44TP-050
CAS:<p>TP-050: potent, selective NMDAR agonist, EC50 0.51 µM (GluN2A), 9.6 µM (GluN2D), BBB permeable, boosts hippocampal LTP.</p>Formula:C16H15ClF2N6OColor and Shape:SolidMolecular weight:380.78(R)-AMPA
CAS:<p>inactive enantiomer of AMPA</p>Formula:C7H10N2O4Purity:98%Color and Shape:SolidMolecular weight:186.17BeKm-1
CAS:<p>Potent, selective hERG (KV11.1) blocker; doesn't affect 14 other K+ channels; extends QTc in rabbit heart dose-dependently.</p>Formula:C174H261N51O52S6Purity:98%Color and Shape:SolidMolecular weight:4091.65NSC799462
<p>NSC799462, a triazole inhibitor, specifically targets p97 ATPase, exerting its effect by binding to a designated site on the p97 enzyme. This interaction induces localized structural alterations in p97, effectively inhibiting its ATPase activity with an IC 50 value of 15 nM.</p>Formula:C30H32F2N6O3SColor and Shape:SolidMolecular weight:594.68NF110
CAS:<p>P2X3 antagonist</p>Formula:C41H32N6NaO17S4Purity:98%Color and Shape:SolidMolecular weight:1031.97N-hydroxy Riluzole
CAS:<p>N-hydroxy Riluzole, a metabolite of riluzole, is mainly produced by CYP1A2 in human liver.</p>Formula:C8H5F3N2O2SColor and Shape:SolidMolecular weight:250.20Cavα2δ-IN-1
CAS:<p>Cavα2δ-IN-1 demonstrates exceptional specificity for voltage-gated calcium channels Cavα2δ-1 (with a Ki value of 6 nM), in comparison to Cavα2δ-2 (with a Ki</p>Formula:C18H27N5OColor and Shape:SolidMolecular weight:329.448Sulcardine 2HCl
CAS:<p>Sulcardine 2HCl is a multi-ion channel blocker that blocks the properties of hERG and hNav1.5 channels and can be used to study atrial fibrillation.</p>Formula:C24H35Cl2N3O4SPurity:99.33% - 99.76%Color and Shape:SoildMolecular weight:532.523EVT-401
<p>EVT-401 (P2X7 receptor antagonist-1), a purinergic P2X7 receptor antagonist, demonstrates efficacy in combating neuroinflammation [1].</p>Formula:C22H20F4N2O3Color and Shape:SolidMolecular weight:436.4ω-Conotoxin GVIA
CAS:<p>Peptide neurotoxin; selectively and reversibly blocks N-type calcium channels (IC50 = 0.15 nM). Reduces (RS)-3,5-DHPG -induced long term depression in vivo.</p>Formula:C120H182N38O43S6Purity:98%Color and Shape:SolidMolecular weight:3037A-317567
CAS:A-317567 is a potent acid-sensing ion channel 3 (ASIC-3) inhibitor with an IC50 of 1.025 μM, and it has antidepressant and antinociception effects[1][2].Formula:C27H31N3Purity:98%Color and Shape:SolidMolecular weight:397.56Cevadine
<p>Cevadine is a natural product that can be used as a reference standard.</p>Formula:C32H49NO9Color and Shape:SolidMolecular weight:591.742GsMTx4
CAS:<p>GsMTx-4, mechanosensitive and stretch-activated ion channel inhibitor (CAS 1209500-46-8).</p>Formula:C185H273N49O45S6Purity:98%Color and Shape:SolidMolecular weight:4095.84Resolvin D2
CAS:<p>Resolvin D2 (RvD2) is a TRPV1 inhibitor and pro-ablative mediator with anti-inflammatory, anti-infective and pro-ablative effects.</p>Formula:C22H32O5Purity:98%Color and Shape:SolidMolecular weight:376.49Caloxin 2A1 acetate
<p>Caloxin 2A1 acetate is an inhibitor of extracellular plasma membrane Ca2+-ATPase (PMCA) peptide.</p>Formula:C66H95N19O24Purity:98.2%Color and Shape:SolidMolecular weight:1538.5712,14-Dichlorodehydroabietic acid
CAS:<p>12,14-Dichlorodehydroabietic acid activates BK channels, blocks GABA A receptors, and increases calcium and neurotransmitter release.</p>Formula:C20H26Cl2O2Color and Shape:SolidMolecular weight:369.33Halazone
CAS:<p>Halazone (Pantocid) is fine white powder with an odor of chlorine. It has been widely used to disinfect drinking water.</p>Formula:C7H5Cl2NO4SPurity:98.64%Color and Shape:Physical Description Fine White Powder With An Odor Of Chlorine (Ntp 1992)Molecular weight:270.09CW2158
<p>CW2158 (Compound 13) is a modulator of exportin1 (XPO1). It disrupts chromatin binding and inhibits the activation of NFAT transcription factors and T cells.</p>Formula:C14H8F4N4O2Molecular weight:340.05834Eltanexor
CAS:<p>Eltanexor, an oral XPO1 inhibitor, induces apoptosis in leukemia cells; EC50=60.9 nM.</p>Formula:C17H10F6N6OPurity:99.6% - ≥98%Color and Shape:SolidMolecular weight:428.29AmmTX3
<p>KV4 channel blocker that inhibits A-type K+ current in mouse neurons; requires DPP6 and DPP10 for effect.</p>Formula:C158H262N50O48S6Purity:98%Color and Shape:SolidMolecular weight:3822.47Verruculogen
CAS:<p>Verruculogen, a toxin from Penicillium/Aspergillus, blocks Ca2+-K+ channels and halts mammalian M phase.</p>Formula:C27H33N3O7Purity:98%Color and Shape:White PowderMolecular weight:511.57Furosemide sodium
CAS:<p>Furosemide sodium: potent NKCC inhibitor, loop diuretic, treats heart failure, hypertension, edema, selective GABAA antagonist.</p>Formula:C12H10ClN2NaO5SPurity:99.52% - >99.99%Color and Shape:SolidMolecular weight:352.73GS-9191 PM
<p>GS-9191 PM: novel antitumorviral bis-amide prodrug, inhibits MDR1/BCRP, has antiproliferative activity.</p>Formula:C11H16N6OPurity:99.79%Color and Shape:SoildMolecular weight:248.28SLC26A3-IN-2
CAS:<p>Vilobelimab (CaCP-29) is a human-mouse chimeric IgG antibody targeting human complement component 5a, a C5a inhibitor that inhibits neutrophil activation.</p>Formula:C19H13ClN2O2SPurity:99.86%Color and Shape:SolidMolecular weight:368.84SNX-482
CAS:Potent CaV2.3 calcium channel blocker, selective, voltage-dependent, with 30 nM IC50. Offers antinociceptive effects on C and Aδ fibres.Formula:C192H274N52O60S7Purity:98%Color and Shape:SolidMolecular weight:4495.01TRPA1-IN-2
CAS:<p>TRPA1-IN-2 is a potent and orally active TRPA1 inhibitor with an IC50 value of 0.04 µM.TRPA1-IN-2 has anti-inflammatory activity.</p>Formula:C24H25F3N4OPurity:98.05%Color and Shape:SoildMolecular weight:442.48NSC156529
CAS:<p>NSC156529 suppresses AKT1, reduces cancer cell growth in vitro, and inhibits prostate tumors in vivo.</p>Formula:C28H21ClS2Purity:98%Color and Shape:SolidMolecular weight:457.05Apamin
CAS:<p>Apamin: 18-amino acid bee venom peptide, blocks SK channels, anti-inflammatory, anti-fibrotic, strongly basic.</p>Formula:C79H131N31O24S4Purity:98%Color and Shape:SolidMolecular weight:2027.34(Rac)-Tezacaftor
CAS:<p>(Rac)-Tezacaftor, a racemate, corrects F508del CFTR for cystic fibrosis research.</p>Formula:C26H27F3N2O6Color and Shape:SolidMolecular weight:520.5c-Met-IN-23
<p>c-Met-IN-23 (Compound 12g) functions as a c-Met inhibitor with an IC50 of 0.052 μM against c-Met. It also inhibits the MDR1 and MRP1/2 pumps in cancerous HepG2 and BxPC3 cells. As such, c-Met-IN-23 serves as an anticancer agent.</p>Formula:C16H13N7OMolecular weight:319.118163-Aminopropylphosphinic acid
CAS:<p>3-Aminopropylphosphinic acid (3-APPA) is a phosphonic analog of gamma-aminobutyric acid (GABA).</p>Formula:C3H10NO2PColor and Shape:SolidMolecular weight:123.092Analgesic/antidepressant agent-1
<p>Analgesic/antidepressant agent-1 (Compound k1) is an orally active N-acetylamino chloro ketone derivative capable of crossing the blood-brain barrier. It exhibits high affinity for NMDA receptors and demonstrates analgesic, anti-inflammatory, and antidepressant properties, with low psychotomimetic activity.</p>Formula:C22H25ClN2O2Color and Shape:SolidMolecular weight:384.9ProTx II
CAS:<p>Selective NaV1.7 inhibitor, alters activation, reduces current, 100x more selective for 1.7 over other Na+ channels.</p>Formula:C168H250N46O41S8Purity:98%Color and Shape:SolidMolecular weight:3826.59Astressin 2B
CAS:<p>CRF2 antagonist with IC50 of 1.3 nM; >500 nM for CRF1. Aids gastric emptying.</p>Formula:C183H307N49O53Purity:98%Color and Shape:SolidMolecular weight:4041.69Dihydroisopimaric acid
CAS:<p>Dihydroisopimaric acid opens BKαβ1 channels - large Ca²⁺-activated K⁺ conductors, verified by whole-cell voltage clamp.</p>Formula:C20H32O2Color and Shape:SolidMolecular weight:304.47Vedroprevir
CAS:<p>Vedroprevir (GS9451), a selective HCV NS3 protease inhibitor, targets genotype 1 HCV.</p>Formula:C45H60ClN7O9SColor and Shape:SolidMolecular weight:910.53NF864
CAS:NF864, a suramin analog, is a P2X1 receptor inhibitor.Formula:C57H28N6Na12O41S12Purity:98%Color and Shape:SolidMolecular weight:2113.5rac-trans-4-hydroxy Glyburide
CAS:<p>rac-trans-4-hydroxy Glyburide, a metabolite of glyburide, inhibits binding at SUR1/Kir6.2 sites with IC50 values of 0.95 and 100 nM.</p>Formula:C23H28ClN3O6SColor and Shape:SolidMolecular weight:510.0AQP4 (201-220)
CAS:<p>AQP4 (201-220) is the encephalitogenic epitope of AQP-4. AQP4 (201-220) can induce experimental autoimmune encephalomyelitis (EAE), characterized by midline brain lesions, retinal lesions, and lesions at the gray matter/white matter boundary of the spinal cord. AQP-4 is the target antigen in neuromyelitis optica.</p>Formula:C97H143N27O27SColor and Shape:SolidMolecular weight:2151.4N-Arachidonoyl Taurine
CAS:<p>N-Arachidonoyl taurine, an amino acid, activates TRPV1/TRPV4, is metabolized by lipoxygenase, and affects insulin secretion and calcium flux.</p>Formula:C22H37NO4SColor and Shape:SolidMolecular weight:411.6P2X4 antagonist-3
<p>P2X4 antagonist-3 (Compound 14c) is a P2X4 inhibitor with an IC50 value of 1.2 μM. It holds potential for research into neuroinflammation, chronic pain, and cancer progression.</p>Formula:C19H20FN3O4Color and Shape:SolidMolecular weight:373.38JAMI1001A
CAS:<p>JAMI1001A enhances AMPA receptor signaling, slows deactivation/desensitization for flip/flop isoforms.</p>Formula:C16H17F3N4O3SColor and Shape:SolidMolecular weight:402.39PDDHV
CAS:<p>PDDHV: a capsaicin-like vanilloid selective for rat TRPV1; induces Ca2+ uptake in neurons, EC50 of 70 nM.</p>Formula:C49H72O11Color and Shape:SolidMolecular weight:837.09AHN-683
CAS:AHN-683 is a fluorescent ligand. It was used for peripheral-type benzodiazepine receptors.Formula:C42H32FN3O7Purity:98%Color and Shape:SolidMolecular weight:709.72Hyp9
CAS:<p>Hyp9, a specific agonist for the transient receptor potential canonical 6 (TRPC6) channel, is utilized in spinal cord injury (SCI) research [1].</p>Formula:C18H26O5Color and Shape:SolidMolecular weight:322.40Atagabalin
CAS:<p>Atagabalin (PD 0200390), a gabamimetic for insomnia treatment and related to gabapentin, was halted due to poor trial outcomes.</p>Formula:C10H19NO2Color and Shape:SolidMolecular weight:185.26Cyclic ADP-ribose ammonium
<p>cADPR ammonium is a second messenger that boosts cytosolic calcium via Ryanodine receptors and TRPM2 channels.</p>Color and Shape:LiquidChlorotoxin
CAS:<p>Chlorotoxin: 36-amino acid peptide from deathstalker scorpion venom; blocks small chloride channels.</p>Formula:C158H249N53O47S11Purity:98%Color and Shape:SolidMolecular weight:3995.71NSC265473
CAS:<p>NSC265473 is an ABCG2 substrate.</p>Formula:C21H35N3O4SColor and Shape:SolidMolecular weight:425.58Foslevcromakalim
CAS:<p>Foslevcromakalim (QLS-101), an ATP-sensitive potassium channel opener, serves as a proagent for ocular hypotensive effects [1] [2].</p>Formula:C16H19N2O6PColor and Shape:SolidMolecular weight:366.31Antidepressant agent 3
<p>Agent 3: orally active, antidepressant, anxiolytic, boosts performance and cognition.</p>Formula:C17H30ClN5O2SColor and Shape:SolidMolecular weight:403.97Mambalgin 1
CAS:<p>ASIC1a inhibitor; IC50: 192 nM (human), 72 nM (dimer); inactive channel binding; selective; pain response delay.</p>Formula:C272H429N85O84S10Purity:98%Color and Shape:SolidMolecular weight:6554.51ProTx-I
CAS:<p>Selective blocker for CaV3.1 (IC50 = 0.2 μM), CaV3.2 (31.8 μM), also inhibits NaV1.8 and blocks KV2.1 channels.</p>Formula:C171H245N53O47S6Purity:98%Color and Shape:SolidMolecular weight:3987.51N-Oleoyl Glutamine
CAS:<p>N-Oleoyl Glutamine (Oleoyl-L-glutamine) antagonizes TRPV1 of the transient receptor potential (TRP) calcium channel.</p>Formula:C23H42N2O4Purity:99.61%Color and Shape:SolidMolecular weight:410.595-Hydroxy-2′,3,4′,7-tetramethoxyflavone
CAS:5-Hydroxy-2′,3,4′,7-tetramethoxyflavone shows weak ABCG2 inhibitory potency with IC50s of 3.27 and 3.89 µM in the Hoechst 33342 and pheophorbide A assays.Formula:C19H18O7Purity:98%Color and Shape:SoildMolecular weight:358.34(±)17-HETE
CAS:<p>Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites.</p>Formula:C20H32O3Color and Shape:SolidMolecular weight:320.473RuBi-GABA
CAS:<p>Ruthenium-bipyridine-triphenylphosphine caged GABA</p>Formula:C42H39F6N5O2P2RuPurity:98%Color and Shape:SolidMolecular weight:922.8Kurtoxin
<p>Kurtoxin is a selective Cav3 (T-type) voltage-gated Ca2+ channel gating inhibitor, exhibiting a dissociation constant (Kd) of 15 nM for the Cav3.1 (α1G T-type)</p>Formula:C324H478N94O90S8Purity:98%Color and Shape:SolidMolecular weight:7386.36GSK2332255B
CAS:<p>GSK2332255B: potent TRPC3/6 antagonist; IC50 5 nM (TRPC3), 4 nM (TRPC6); over 100-fold selectivity vs other Ca2+ channels.</p>Formula:C18H19ClFN3O3SColor and Shape:SolidMolecular weight:411.88HG1 Toxin
<p>HG1 Toxin is a peptide found in the venom of the scorpion Heterometrus fulvipes, known for its ability to inhibit the potassium channel Kv1.3 (potassium channel Kv1.3). Additionally, HG1 Toxin exhibits trypsin inhibitory activity (Ki=107 nM), making it useful for research into autoimmune diseases.</p>Formula:C337H503N103O97S6Molecular weight:7736.59176L-Palmitoylcarnitine TFA
<p>L-Palmitoylcarnitine TFA: long-chain fat metabolite that disrupts membranes in ischaemia & inhibits KATP channels via Kir6.2 interaction.</p>Formula:C25H46F3NO6Color and Shape:SolidMolecular weight:513.63Ziconotide
CAS:<p>Ziconotide: analgesic from cone snail for severe, chronic pain; synthetic ω-conotoxin.</p>Formula:C102H172N36O32S7Purity:98%Color and Shape:White PowderMolecular weight:2639.13SC 4453
CAS:<p>SC 4453 is a digoxin analog and a cardiac glycoside derivative.</p>Formula:C41H64N2O12Color and Shape:SolidMolecular weight:776.965APETx2
CAS:<p>ASIC3 inhibitor; IC50: 63 nM (rat), 175 nM (human). Blocks NaV1.8, NaV1.2; analgesic for acid/inflammatory pain.</p>Formula:C196H280N54O61S6Purity:98%Color and Shape:SolidMolecular weight:4561.06Nav1.7-IN-8
CAS:<p>Nav1.7-IN-8 selectively inhibits NaV1.7 over hNaV1.1/1.5, affects CYP2C9/3A4 (IC50: 0.17/0.077 μM), and provides rodent pain relief.</p>Formula:C21H12ClF2N5O4S2Color and Shape:SolidMolecular weight:535.93Levamlodipine besylate Hemipentahydrate
CAS:<p>Levamlodipine besylate hemipentahydrate is the besylate hemipentahydrate salt form of Levamlodipine. It is an orally effective calcium channel blocker with antioxidative and vasodilatory properties. This compound can reduce serum malondialdehyde (MDA) levels, enhance the activity of superoxide dismutase (SOD), and alleviate oxidative stress. Levamlodipine besylate hemipentahydrate is relevant for research in vascular dementia, hypertension, and cerebrovascular diseases.</p>Formula:C20H25ClN2O5·C6H6O3SH2OColor and Shape:SolidMolecular weight:1224.18ATP Synthesis-IN-2
<p>ATP Synthesis-IN-2 (Compound 5) serves as a potent inhibitor of ATP synthesis activity, displaying significant antibacterial properties with an IC50 value of 0.</p>Color and Shape:Odour SolidEbio3
<p>Ebio3 is a selective potassium ion channel (KCNQ2) inhibitor with an IC50 of 1.2 nM. It binds to the KCNQ2 channel via its hydrophobic tail, causing the inward movement of the S6 helix, which results in the closure of the internal gate. The inhibitory effect of Ebio3 is equally effective on pathogenic KCNQ2 mutants, such as R75C and I238L, reducing their outward current by approximately 80%. Ebio3 holds potential for research in neurological disorders like epilepsy.</p>Formula:C19H23F2N3O2Color and Shape:SolidMolecular weight:363.4Anticonvulsant agent 9
<p>Anticonvulsant agent 9 (compound 4f) is an activator of the α1β2γ2GABA_A receptor, with an EC50 value of 1.24 μM. It inhibits the inactivation of Nav1.2 channels and exhibits significant anticonvulsant activity.</p>Formula:C22H24N4O2Color and Shape:SolidMolecular weight:376.45
