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Membrane Transporter/Ion Channel

Membrane Transporter/Ion Channel

Membrane transporter and ion channel inhibitors are compounds that block the function of proteins responsible for the transport of ions, nutrients, and other molecules across cell membranes. These inhibitors are crucial for studying the regulation of cellular homeostasis, signal transduction, and neurotransmission. Membrane transporter and ion channel inhibitors are also important in developing treatments for disorders such as epilepsy, cardiovascular diseases, and metabolic syndromes. At CymitQuimica, we provide a diverse selection of high-quality membrane transporter and ion channel inhibitors to support your research in physiology, neuroscience, and pharmacology.

Subcategories of "Membrane Transporter/Ion Channel"

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Found 2293 products of "Membrane Transporter/Ion Channel"

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  • CymitQuimica logo
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    Anticonvulsant agent 8

    <p>Anticonvulsant agent 8 (compound D4) is a chemical used in treating epilepsy by inhibiting GABAA currents. In mouse models, its ED50 values are 2.23 mg/kg for the maximal electroshock (MES) test and 24.60 mg/kg for the pentylenetetrazol (PTZ) test.</p>
    Formula:C15H11N5O
    Color and Shape:Solid
    Molecular weight:277.28

    Ref: TM-T205302

  • BeKm-1
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    BeKm-1

    CAS:
    <p>Potent, selective hERG (KV11.1) blocker; doesn't affect 14 other K+ channels; extends QTc in rabbit heart dose-dependently.</p>
    Formula:C174H261N51O52S6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:4091.65

    Ref: TM-TP2072

  • Phe-Met-Arg-Phe, amide
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    Phe-Met-Arg-Phe, amide

    CAS:
    Phe-Met-Arg-Phe amide activates K+ current in neurons (ED50=23 nM), co-localizes with neuropeptide Y in brain regions.
    Formula:C29H42N8O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:598.76

    Ref: TM-TP1858

  • DAA-1106
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    DAA-1106

    CAS:
    <p>DAA-1106 is a potent and selective ligand for PBR, acting as a potent and selective agonist at the peripheral benzodiazepine receptor.</p>
    Formula:C23H22FNO4
    Purity:99.54%
    Color and Shape:Solid
    Molecular weight:395.42

    Ref: TM-T3173

  • AQP4 (205-215)
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    AQP4 (205-215)

    CAS:
    <p>AQP4 (205-215) is a fragment of the water channel protein Aquaporin-4 (AQP4). This protein is an autoimmune antigen in optic neuromyelitis and, upon binding with CD40, is upregulated and presented in B cells. AQP4 is associated with neuromyelitis optica (NMO), an autoimmune inflammatory disease of the central nervous system (CNS).</p>
    Formula:C48H75N13O17S
    Color and Shape:Solid
    Molecular weight:1138.25

    Ref: TM-TP3218

  • Fumitremorgin C
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    Fumitremorgin C

    CAS:
    <p>Fumitremorgin C (12α-Fumitremorgin C) is a mycotoxin and inhibits ABCG2/BRCP.</p>
    Formula:C22H25N3O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:379.45

    Ref: TM-T15355

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    P-gp inhibitor 13

    <p>P-gp Inhibitor 13, a P-glycoprotein antagonist, can counteract paclitaxel resistance in A2780/T cells, proving valuable for advanced acute myeloid leukemia</p>
    Formula:C32H34O8
    Color and Shape:Solid
    Molecular weight:546.61

    Ref: TM-T78974

  • Elgodipine
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    Elgodipine

    CAS:
    <p>Elgodipine decreases angina severity, inhibits muscle growth, and is voltage-sensitive, showing promise for angina treatment.</p>
    Formula:C29H33FN2O6
    Purity:98.95% - 99.50%
    Color and Shape:Solid
    Molecular weight:524.58

    Ref: TM-T68060

  • Ouabagenin
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    Ouabagenin

    CAS:
    <p>Ouabagenin, a naturally occurring LXR ligand with selective agonist activity, functions as an EC 3.6.3.9 (Na(+)/K(+)-transport ATPase) inhibitor [1] [2].</p>
    Formula:C23H34O8
    Color and Shape:Solid
    Molecular weight:438.51

    Ref: TM-TN7752

  • Milbemycin A4
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    Milbemycin A4

    CAS:
    <p>Milbemycin A4, a distinguished member of the macrocyclic lactones family featuring a unique spiroketal group, is derived from the fermentation of the soil bacterium Streptomyces hygroscopicus subsp. aureolacrimosus. It acts by enhancing the opening of glutamate and GABA-gated chloride channels, rendering it effective as both a nematocide and insecticide.</p>
    Formula:C32H46O7
    Color and Shape:Solid
    Molecular weight:542.713

    Ref: TM-TN7268

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    H-Lys-Tyr-OH TFA

    <p>Lysyltyrosine TFA is a dipeptide that may enhance brain function by boosting noradrenaline and tyrosine release.</p>
    Formula:C17H24F3N3O6
    Color and Shape:Solid
    Molecular weight:423.38

    Ref: TM-T74045

  • TRPV4 antagonist 4
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    TRPV4 antagonist 4

    CAS:
    <p>Potent TRPV4 blocker with 22.65 nM IC50; inhibits current and aids acute lung injury.</p>
    Formula:C28H32Cl2N6O
    Color and Shape:Solid
    Molecular weight:539.50

    Ref: TM-T74832

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    Analgesic/antidepressant agent-1

    <p>Analgesic/antidepressant agent-1 (Compound k1) is an orally active N-acetylamino chloro ketone derivative capable of crossing the blood-brain barrier. It exhibits high affinity for NMDA receptors and demonstrates analgesic, anti-inflammatory, and antidepressant properties, with low psychotomimetic activity.</p>
    Formula:C22H25ClN2O2
    Color and Shape:Solid
    Molecular weight:384.9

    Ref: TM-T205604

  • TRPV4 antagonist 3
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    TRPV4 antagonist 3

    CAS:
    <p>TRPV4 antagonist 3 is a TRPV4 antagonist (p IC 50 = 8.4).</p>
    Formula:C20H18F4N4O3S
    Color and Shape:Solid
    Molecular weight:470.44

    Ref: TM-T40306

  • (R)-AMPA
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    (R)-AMPA

    CAS:
    <p>inactive enantiomer of AMPA</p>
    Formula:C7H10N2O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:186.17

    Ref: TM-T23220

  • Vanzacaftor
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    Vanzacaftor

    CAS:
    <p>Vanzacaftor is a CFTR modulator improving protein processing and surface trafficking, restoring chloride transport and aiding cystic fibrosis therapy research.</p>
    Formula:C32H39N7O4S
    Purity:99.14%
    Color and Shape:Solid
    Molecular weight:617.76

    Ref: TM-T74417

  • TRPV1 activator-2
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    TRPV1 activator-2

    CAS:
    <p>TRPV1 activator-2 (Compound 9), a capsaicin head analog, engages in targeted interactions with channel residues at the lipid-water interface [1].</p>
    Formula:C19H29NO3
    Color and Shape:Solid
    Molecular weight:319.44

    Ref: TM-T74742

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    Tertiapin LQ

    <p>Kir1.1 channel blocker, 250x selective; Kd: Kir1.1 (1.1 nM), Kir3.1/3.2 (274 nM), Kir3.1/3.4 (361 nM). Tertiapin-Q derivative.</p>
    Formula:C106H179N33O24S4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:2428.03

    Ref: TM-TP2113

  • GX 201
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    GX 201

    CAS:
    <p>GX 201 is a selective NaV1.7 inhibitor, IC50 of &lt; 3.2 nM for hNaV1.7.</p>
    Formula:C25H27ClF4N2O4S
    Purity:99.81%
    Color and Shape:Solid
    Molecular weight:563

    Ref: TM-T9647

  • Agitoxin-2
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    Agitoxin-2

    CAS:
    Potent Shaker K+ channel blocker (Ki = 0.64 nM). Also inhibits Kv1.3, Kv1.6 and Kv1.1 K+ channels (Ki values are 4, 37 and 44 pM respectively).
    Formula:C169H278N54O48S8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:4090.87

    Ref: TM-TP2089