Membrane Transporter/Ion Channel
Membrane transporter and ion channel inhibitors are compounds that block the function of proteins responsible for the transport of ions, nutrients, and other molecules across cell membranes. These inhibitors are crucial for studying the regulation of cellular homeostasis, signal transduction, and neurotransmission. Membrane transporter and ion channel inhibitors are also important in developing treatments for disorders such as epilepsy, cardiovascular diseases, and metabolic syndromes. At CymitQuimica, we provide a diverse selection of high-quality membrane transporter and ion channel inhibitors to support your research in physiology, neuroscience, and pharmacology.
Subcategories of "Membrane Transporter/Ion Channel"
- ABC(3 products)
- ATPase(97 products)
- Adiponectin receptor(5 products)
- CFTR(64 products)
- CGRP Receptor(53 products)
- Calcium Channel(520 products)
- Chloride channel(51 products)
- GABA Receptor(351 products)
- Monoamine Transporter(26 products)
- Monocarboxylate transporter(18 products)
- NKCC(2 products)
- NPC1L1(3 products)
- Na-K-Cl cotransporter(9 products)
- OAT(28 products)
- OCT(7 products)
- P-gp(53 products)
- Potassium Channel(280 products)
- Proton pump(40 products)
- SGLT(31 products)
- Sodium Channel(203 products)
- TRP/TRPV Channel(94 products)
Show 13 more subcategories
Found 2402 products of "Membrane Transporter/Ion Channel"
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TRPV1 activator-1
CAS:<p>TRPV1 Activator-1 (Compound 8), a capsaicin analog featuring a modified neck structure, specifically interacts with the T551 residue [1].</p>Formula:C18H27NO2SColor and Shape:SolidMolecular weight:321.48Milbemycin A4
CAS:<p>Milbemycin A4, a distinguished member of the macrocyclic lactones family featuring a unique spiroketal group, is derived from the fermentation of the soil bacterium Streptomyces hygroscopicus subsp. aureolacrimosus. It acts by enhancing the opening of glutamate and GABA-gated chloride channels, rendering it effective as both a nematocide and insecticide.</p>Formula:C32H46O7Color and Shape:SolidMolecular weight:542.713Tacrine hydrochloride
CAS:Tacrine: a cholinergic agonist, anticholinesterase; inhibits AChE/BChE with IC50s of 31/25.6 nM.Formula:C13H15ClN2Purity:98%Color and Shape:SolidMolecular weight:234.73TRPV4 antagonist 4
CAS:<p>Potent TRPV4 blocker with 22.65 nM IC50; inhibits current and aids acute lung injury.</p>Formula:C28H32Cl2N6OColor and Shape:SolidMolecular weight:539.50Anticonvulsant agent 8
<p>Anticonvulsant agent 8 (compound D4) is a chemical used in treating epilepsy by inhibiting GABAA currents. In mouse models, its ED50 values are 2.23 mg/kg for the maximal electroshock (MES) test and 24.60 mg/kg for the pentylenetetrazol (PTZ) test.</p>Formula:C15H11N5OColor and Shape:SolidMolecular weight:277.28Linoleic Acid Amide
CAS:<p>Linoleic Acid Amide (Linoleamide) is derived from linoleic acid and regulates Ca2+ flux by inhibiting the sarco/endoplasmic reticulum Ca2+-ATPase.</p>Formula:C18H33NOPurity:98%Color and Shape:SolidMolecular weight:279.46Withasomniferolide B
CAS:<p>Withasomniferolide B, a withanolide from Withania somnifera root, activates GABAA receptors.</p>Formula:C28H36O4Color and Shape:SolidMolecular weight:436.58GaTx2
CAS:High-affinity ClC-2 blocker (KD ~50 pM), selective over other ClCs/CFTR/GABAC/CaCC/KV1.2; slows activation, no effect on open channels.Formula:C125H199N39O47S6Purity:98%Color and Shape:SolidMolecular weight:3192.54AVLX-125
CAS:<p>AVLX-125 (UCCB01-125), a potent inhibitor of PSD-95 and PDZ domains, exhibits a dissociation constant (Kd) of 10 nM. It is utilized in researching inflammatory pain [1] [2].</p>Formula:C62H104N10O29Color and Shape:SolidMolecular weight:1453.54Resolvin D2 methyl ester
CAS:<p>RvD2 is an anti-inflammatory lipid made from docosahexaenoic acid by 15- and 5-lipoxygenase. Its methyl ester may serve as a prodrug.</p>Formula:C23H34O5Color and Shape:SolidMolecular weight:390.52UCL 1684 dibromide
CAS:<p>apamin-sensitive Ca2+-activated K+ channel (KCa2.1) blocker</p>Formula:C34H30Br2N4Purity:98%Color and Shape:SolidMolecular weight:654.45Dofetilide N-oxide
CAS:Dofetilide N-oxide (UK-116856) is a metabolite of dofetilide. Dofetilide can block potassium channels and is a tertiary antiarrhythmic drug.Formula:C19H27N3O6S2Purity:98%Color and Shape:SolidMolecular weight:457.56BuChE-IN-9
BuChE-IN-9 (compound 22a), an eqBuChE (equine serum-derived butyrylcholinesterase) inhibitor, exhibits potent activity with an IC50 of 173 nM.Formula:C28H34N4O2Color and Shape:SolidMolecular weight:458.6Prilocaine acetate
<p>Prilocaine acetate, an amino amide compound, functions as a Na/K-ATPase inhibitor, exhibiting neurotoxic effects [1] [2].</p>Formula:C15H24N2O3Color and Shape:SolidMolecular weight:280.36Lei-Dab7
CAS:Selective KCa2.2 channel blocker with Kd 3.8 nM, >200-fold specificity, enhances LTP, convulsive in vivo.Formula:C141H236N46O39S6Purity:98%Color and Shape:SolidMolecular weight:3392.06Lyso-Globotriaosylceramide (d18:1)
CAS:<p>Lyso-Gb3, lacking fatty acyl, binds Stx1 with cholesterol and phosphatidylcholine, not Stx2; lowers neutrophil viability; accumulates in Fabry disease.</p>Formula:C36H67NO17Color and Shape:SolidMolecular weight:785.922Lifastuzumab
CAS:<p>Sulfamethoxazole-NO (SMX-NO) is a SMX-NO derivative and is the primary immunogen for sulfonamide hypersensitivity reactions.</p>Purity:97% (SDS-PAGE); 99.5% (SEC-HPLC) - 97% (SDS-PAGE); 99.5% (SEC-HPLC)Color and Shape:LiquidMolecular weight:145.5 kDaP-gp inhibitor 13
<p>P-gp Inhibitor 13, a P-glycoprotein antagonist, can counteract paclitaxel resistance in A2780/T cells, proving valuable for advanced acute myeloid leukemia</p>Formula:C32H34O8Color and Shape:SolidMolecular weight:546.61PDZ1 Domain inhibitor peptide
CAS:Novel cyclic peptide that disrupts interaction between GluR6 and PSD-95Formula:C38H61N9O11Purity:98%Color and Shape:SolidMolecular weight:819.94MRS4596
MRS4596: selective P2X4 blocker, IC50 1.38 μM, neuroprotective in stroke research.Formula:C21H14N5NaO3SColor and Shape:SolidMolecular weight:439.42
