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Membrane Transporter/Ion Channel

Membrane Transporter/Ion Channel

Membrane transporter and ion channel inhibitors are compounds that block the function of proteins responsible for the transport of ions, nutrients, and other molecules across cell membranes. These inhibitors are crucial for studying the regulation of cellular homeostasis, signal transduction, and neurotransmission. Membrane transporter and ion channel inhibitors are also important in developing treatments for disorders such as epilepsy, cardiovascular diseases, and metabolic syndromes. At CymitQuimica, we provide a diverse selection of high-quality membrane transporter and ion channel inhibitors to support your research in physiology, neuroscience, and pharmacology.

Subcategories of "Membrane Transporter/Ion Channel"

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Found 2402 products of "Membrane Transporter/Ion Channel"

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  • 2,4,6-Tri-tert-butylphenol
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    2,4,6-Tri-tert-butylphenol

    CAS:
    <p>2,4,6-Tri-tert-butylphenol inhibits the Ca2+ ATPase activity of human red blood cell membranes and can be used in related research in the field of life sciences.</p>
    Formula:C18H30O
    Purity:99.55%
    Color and Shape:Solid
    Molecular weight:262.43

    Ref: TM-TN9644

  • α5-GABAA receptor modulator 1
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    α5-GABAA receptor modulator 1

    <p>α5-GABAA receptor modulator 1 (Compound A-4) is a selective silent allosteric modulator (SAM) targeting the α5 subunit of GABAA receptors, useful for research into central nervous system (CNS) disorders.</p>
    Formula:C21H20FN3O4
    Color and Shape:Solid
    Molecular weight:397.4

    Ref: TM-T205217

  • GX 201
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    GX 201

    CAS:
    <p>GX 201 is a selective NaV1.7 inhibitor, IC50 of &lt; 3.2 nM for hNaV1.7.</p>
    Formula:C25H27ClF4N2O4S
    Purity:99.81%
    Color and Shape:Solid
    Molecular weight:563

    Ref: TM-T9647

  • Hyp9
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    Hyp9

    CAS:
    <p>Hyp9, a specific agonist for the transient receptor potential canonical 6 (TRPC6) channel, is utilized in spinal cord injury (SCI) research [1].</p>
    Formula:C18H26O5
    Color and Shape:Solid
    Molecular weight:322.40

    Ref: TM-T75550

  • TRPA1-IN-1
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    TRPA1-IN-1

    CAS:
    <p>TRPA1-IN-1 is a potent, selective antagonist of the TRPA1 channel, demonstrating significant oral bioavailability as a small molecule.</p>
    Formula:C19H17ClN6O3
    Color and Shape:Solid
    Molecular weight:412.83

    Ref: TM-T39935

  • 17α-Hydroxywithanolide D
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    17α-Hydroxywithanolide D

    <p>17alpha-Hydroxywithanolide D is an allosteric modulator of the NMDA receptor, with an IC50 of 44.24 nM. This compound exhibits neuroprotective properties and can be utilized in Alzheimer's disease research.</p>
    Formula:C28H46O7
    Color and Shape:Solid
    Molecular weight:494.661

    Ref: TM-T204406

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    CBP-1008

    <p>CBP-1008 is a dual-ligand peptide-drug conjugate (PDC) with MMAE, targeting folate receptor (FRα) and TRPV6. It exhibits high binding affinity to FRα and low affinity to TRPV6. CBP-1008 shows antitumor activity and can be utilized for research in advanced solid tumors such as colorectal cancer, breast cancer, non-small cell lung cancer, ovarian cancer, adrenocortical carcinoma, and follicular dendritic cell sarcoma.</p>
    Color and Shape:Odour Solid

    Ref: TM-TP2953

  • (+)-Lycoctonine
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    (+)-Lycoctonine

    CAS:
    Compound TJS1874 is a useful organic compound for research related to life sciences. The catalog number is TJS1874 and the CAS number is 26000-17-9.
    Formula:C25H41NO7
    Color and Shape:Solid
    Molecular weight:467.6

    Ref: TM-TJS1874

  • Lei-Dab7
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    Lei-Dab7

    CAS:
    Selective KCa2.2 channel blocker with Kd 3.8 nM, >200-fold specificity, enhances LTP, convulsive in vivo.
    Formula:C141H236N46O39S6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3392.06

    Ref: TM-TP2007

  • Albanin A
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    Albanin A

    <p>Albanin A is a useful organic compound for research related to life sciences and the catalog number is T124310.</p>
    Formula:C20H18O6
    Color and Shape:Solid
    Molecular weight:354.358

    Ref: TM-T124310

  • GaTx2
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    GaTx2

    CAS:
    High-affinity ClC-2 blocker (KD ~50 pM), selective over other ClCs/CFTR/GABAC/CaCC/KV1.2; slows activation, no effect on open channels.
    Formula:C125H199N39O47S6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3192.54

    Ref: TM-TP2027

  • 1-(1-Methyl-1h-pyrazol-4-yl)-ethanone
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    1-(1-Methyl-1h-pyrazol-4-yl)-ethanone

    CAS:
    1-(1-Methyl-1h-pyrazol-4-yl)-ethanone is a high purity biochemical reagent that can be used in research related to life sciences.
    Formula:C6H8N2O
    Purity:99.92%
    Color and Shape:Solid
    Molecular weight:124.14

    Ref: TM-TN9428

  • GeX-2
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    GeX-2

    CAS:
    <p>GeX-2 is a truncated analogue of αO-conotoxin. It has the ability to activate GABAB receptors and inhibit α9α10nAChR as well as CaV2.2 channels. Additionally, GeX-2 is effective in alleviating pain in a rat model of chronic constriction injury.</p>
    Formula:C103H169N43O27
    Color and Shape:Solid
    Molecular weight:2441.72

    Ref: TM-TP3132

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    Ebio3

    <p>Ebio3 is a selective potassium ion channel (KCNQ2) inhibitor with an IC50 of 1.2 nM. It binds to the KCNQ2 channel via its hydrophobic tail, causing the inward movement of the S6 helix, which results in the closure of the internal gate. The inhibitory effect of Ebio3 is equally effective on pathogenic KCNQ2 mutants, such as R75C and I238L, reducing their outward current by approximately 80%. Ebio3 holds potential for research in neurological disorders like epilepsy.</p>
    Formula:C19H23F2N3O2
    Color and Shape:Solid
    Molecular weight:363.4

    Ref: TM-T205242

  • Quinine hemisulfate hydrate
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    Quinine hemisulfate hydrate

    CAS:
    <p>Quinine hemisulfate hydrate: anti-malaria, derived from cinchona bark, inhibits mouse Slo3 channels with IC50 169 μM.</p>
    Formula:C20H26N2O3H2O4S·H2O
    Color and Shape:Solid
    Molecular weight:391.47

    Ref: TM-T75333

  • Agitoxin-2
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    Agitoxin-2

    CAS:
    Potent Shaker K+ channel blocker (Ki = 0.64 nM). Also inhibits Kv1.3, Kv1.6 and Kv1.1 K+ channels (Ki values are 4, 37 and 44 pM respectively).
    Formula:C169H278N54O48S8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:4090.87

    Ref: TM-TP2089

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    PptT-IN-4

    PptT-IN-4 (Compound 3a) is a PptT inhibitor exhibiting an IC50 of 0.71 μM.
    Formula:C17H23N3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:269.38

    Ref: TM-T78714

  • Nipecotic acid
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    Nipecotic acid

    CAS:
    <p>Compound PDK0243, with CAS No. 498-95-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0243 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>
    Formula:C6H11NO2
    Color and Shape:Off-White To Pale Yellow-Beige Powder
    Molecular weight:129.16

    Ref: TM-PDK0243

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    P-gp inhibitor 15

    P-gp Inhibitor 15 (compound 7a), a nonsubstrate inhibitor of P-glycoprotein (Pgp), inhibits Pgp-ATPase activity and interferes with Pgp-mediated Rhodamine123
    Formula:C35H60N2O4
    Color and Shape:Solid
    Molecular weight:572.86

    Ref: TM-T79261

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    P-gp inhibitor 13

    <p>P-gp Inhibitor 13, a P-glycoprotein antagonist, can counteract paclitaxel resistance in A2780/T cells, proving valuable for advanced acute myeloid leukemia</p>
    Formula:C32H34O8
    Color and Shape:Solid
    Molecular weight:546.61

    Ref: TM-T78974