Membrane Transporter/Ion Channel
Membrane transporter and ion channel inhibitors are compounds that block the function of proteins responsible for the transport of ions, nutrients, and other molecules across cell membranes. These inhibitors are crucial for studying the regulation of cellular homeostasis, signal transduction, and neurotransmission. Membrane transporter and ion channel inhibitors are also important in developing treatments for disorders such as epilepsy, cardiovascular diseases, and metabolic syndromes. At CymitQuimica, we provide a diverse selection of high-quality membrane transporter and ion channel inhibitors to support your research in physiology, neuroscience, and pharmacology.
Subcategories of "Membrane Transporter/Ion Channel"
- ABC(3 products)
- ATPase(93 products)
- Adiponectin receptor(5 products)
- CFTR(64 products)
- CGRP Receptor(52 products)
- Calcium Channel(496 products)
- Chloride channel(49 products)
- GABA Receptor(336 products)
- Monoamine Transporter(23 products)
- Monocarboxylate transporter(17 products)
- NKCC(2 products)
- NPC1L1(3 products)
- Na-K-Cl cotransporter(8 products)
- OAT(27 products)
- OCT(7 products)
- P-gp(53 products)
- Potassium Channel(277 products)
- Proton pump(39 products)
- SGLT(30 products)
- Sodium Channel(202 products)
- TRP/TRPV Channel(93 products)
Show 13 more subcategories
Found 2290 products of "Membrane Transporter/Ion Channel"
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UK-59811 hydrochloride
CAS:<p>UK-59811 hydrochloride, Br-dihydropyridine derivative, blocks Ca V Ab channels in bacteria, IC50: 194 nM.</p>Formula:C22H30BrClN2O5Color and Shape:SolidMolecular weight:517.85ω-Conotoxin MVIIC TFA
<p>ω-Conotoxin MVIIC TFA is a peptide and neurotoxin blocks P-type and q-type voltage-sensitive neuronal Ca ++ channels (VGCCs) radiolabel immunoprecipitation.</p>Formula:C106H178N40O32S7·C2HF3O2Color and Shape:SolidMolecular weight:2863.27GX 201
CAS:<p>GX 201 is a selective NaV1.7 inhibitor, IC50 of < 3.2 nM for hNaV1.7.</p>Formula:C25H27ClF4N2O4SPurity:99.81%Color and Shape:SolidMolecular weight:563FD 12-9
CAS:FD 12-9, Anti-glioblastoma activity. is a flavonoid dimer, acts as a dual inhibitor of P-gp and BCRP, with EC50s of 285 nM and 0.9 nM, respectively.Formula:C51H47N3O11Purity:98%Color and Shape:SolidMolecular weight:877.93Emamectin B1a
CAS:<p>Emamectin B1a can be used in relevant research in the life sciences. Its product number is T37663 and CAS number is 121124-29-6.</p>Formula:C49H75NO13Color and Shape:SolidMolecular weight:886.133Cyclocreatine
CAS:<p>Cyclocreatine, a creatine analogue and substrate for creatine kinase, inhibits creatine metabolism and prostate cancer cell proliferation.</p>Formula:C5H9N3O2Purity:99.864%Color and Shape:SolidMolecular weight:143.14α5-GABAA receptor modulator 1
<p>α5-GABAA receptor modulator 1 (Compound A-4) is a selective silent allosteric modulator (SAM) targeting the α5 subunit of GABAA receptors, useful for research into central nervous system (CNS) disorders.</p>Formula:C21H20FN3O4Color and Shape:SolidMolecular weight:397.4TRPA1-IN-1
CAS:<p>TRPA1-IN-1 is a potent, selective antagonist of the TRPA1 channel, demonstrating significant oral bioavailability as a small molecule.</p>Formula:C19H17ClN6O3Color and Shape:SolidMolecular weight:412.83ABCB1-IN-1
<p>ABCB1-IN-1 (compound 3) is a potent inhibitor of ABCB1 that promotes cell apoptosis.</p>Formula:C36H33F3FeN2O4PSColor and Shape:SolidMolecular weight:733.54Mambalgin 1
CAS:<p>ASIC1a inhibitor; IC50: 192 nM (human), 72 nM (dimer); inactive channel binding; selective; pain response delay.</p>Formula:C272H429N85O84S10Purity:98%Color and Shape:SolidMolecular weight:6554.51TRPA1 Antagonist 3
CAS:<p>TRPA1 Antagonist 3 is a compound with photoswitchable properties that acts as an agonist on the TRPA1 channel, providing the ability for optical control.</p>Formula:C11H8ClN3Color and Shape:SolidMolecular weight:217.66Atagabalin
CAS:<p>Atagabalin (PD 0200390), a gabamimetic for insomnia treatment and related to gabapentin, was halted due to poor trial outcomes.</p>Formula:C10H19NO2Color and Shape:SolidMolecular weight:185.26Agitoxin-2
CAS:Potent Shaker K+ channel blocker (Ki = 0.64 nM). Also inhibits Kv1.3, Kv1.6 and Kv1.1 K+ channels (Ki values are 4, 37 and 44 pM respectively).Formula:C169H278N54O48S8Purity:98%Color and Shape:SolidMolecular weight:4090.87(Iso)-Atagabalin HCl
CAS:<p>(Iso)-Atagabalin HCl(isomer-Atagabalin HCl) is an alpha -2- delta ligand that can be used to treat non-restorative sleep.</p>Formula:C10H20ClNO2Purity:99.26% - >99.99%Color and Shape:SoildMolecular weight:221.72Apamin
CAS:<p>Apamin: 18-amino acid bee venom peptide, blocks SK channels, anti-inflammatory, anti-fibrotic, strongly basic.</p>Formula:C79H131N31O24S4Purity:98%Color and Shape:SolidMolecular weight:2027.34Caloxin 2A1 acetate
<p>Caloxin 2A1 acetate is an inhibitor of extracellular plasma membrane Ca2+-ATPase (PMCA) peptide.</p>Formula:C66H95N19O24Purity:98.2%Color and Shape:SolidMolecular weight:1538.57AQP4 (201-220)
CAS:<p>AQP4 (201-220) is the encephalitogenic epitope of AQP-4. AQP4 (201-220) can induce experimental autoimmune encephalomyelitis (EAE), characterized by midline brain lesions, retinal lesions, and lesions at the gray matter/white matter boundary of the spinal cord. AQP-4 is the target antigen in neuromyelitis optica.</p>Formula:C97H143N27O27SColor and Shape:SolidMolecular weight:2151.4Cavα2δ-IN-1
CAS:<p>Cavα2δ-IN-1 demonstrates exceptional specificity for voltage-gated calcium channels Cavα2δ-1 (with a Ki value of 6 nM), in comparison to Cavα2δ-2 (with a Ki</p>Formula:C18H27N5OColor and Shape:SolidMolecular weight:329.448LU-32-176B
CAS:<p>LU32-176B is a bioactive chemical.</p>Formula:C23H24F2N2O2Color and Shape:SolidMolecular weight:398.45EVT-401
<p>EVT-401 (P2X7 receptor antagonist-1), a purinergic P2X7 receptor antagonist, demonstrates efficacy in combating neuroinflammation [1].</p>Formula:C22H20F4N2O3Color and Shape:SolidMolecular weight:436.43-Aminopropylphosphinic acid
CAS:<p>3-Aminopropylphosphinic acid (3-APPA) is a phosphonic analog of gamma-aminobutyric acid (GABA).</p>Formula:C3H10NO2PColor and Shape:SolidMolecular weight:123.092D-myo-Inositol-1,3-diphosphate (sodium salt)
CAS:<p>D-myo-Inositol-1,3-phosphate (Ins(1,3)P) is an inositol phosphate involved in cellular signal transduction.</p>Formula:C6H12Na2O12P2Color and Shape:SolidMolecular weight:384.08SNX-482
CAS:Potent CaV2.3 calcium channel blocker, selective, voltage-dependent, with 30 nM IC50. Offers antinociceptive effects on C and Aδ fibres.Formula:C192H274N52O60S7Purity:98%Color and Shape:SolidMolecular weight:4495.01Apamin acetate
<p>Apamin acetate: Selective Ca2+-activated K+ channel blocker, 18-amino acid bee venom peptide, promotes synapse repair, anti-inflammatory.</p>Purity:96.97%Color and Shape:SolidElgodipine
CAS:<p>Elgodipine decreases angina severity, inhibits muscle growth, and is voltage-sensitive, showing promise for angina treatment.</p>Formula:C29H33FN2O6Purity:98.95% - 99.50%Color and Shape:SolidMolecular weight:524.58GsMTx4
CAS:<p>GsMTx-4, mechanosensitive and stretch-activated ion channel inhibitor (CAS 1209500-46-8).</p>Formula:C185H273N49O45S6Purity:98%Color and Shape:SolidMolecular weight:4095.84Conantokin-R
CAS:<p>Conantokin-R is an NMDA receptor peptide antagonist (IC50=93 nM); Conantokin-R exhibits anticonvulsant activity; Conantokin-R binds Zn2+ and Mg2+ (Kds 0.15 μM</p>Formula:C127H201N35O49S3Color and Shape:SolidMolecular weight:3098.38Isotachysterol 3
CAS:<p>Isotachysterol 3 boosts calcium transport in gut and bone mobilization in kidneyless rats.</p>Formula:C27H44OColor and Shape:SolidMolecular weight:384.64PptT-IN-4
<p>PptT-IN-4 (Compound 3a) is a PptT inhibitor exhibiting an IC50 of 0.71 μM.</p>Formula:C17H23N3Purity:98%Color and Shape:SolidMolecular weight:269.38P-gp inhibitor 15
<p>P-gp Inhibitor 15 (compound 7a), a nonsubstrate inhibitor of P-glycoprotein (Pgp), inhibits Pgp-ATPase activity and interferes with Pgp-mediated Rhodamine123</p>Formula:C35H60N2O4Color and Shape:SolidMolecular weight:572.86Halazone
CAS:<p>Halazone (Pantocid) is fine white powder with an odor of chlorine. It has been widely used to disinfect drinking water.</p>Formula:C7H5Cl2NO4SPurity:98.64%Color and Shape:Physical Description Fine White Powder With An Odor Of Chlorine (Ntp 1992)Molecular weight:270.096,7-dimethylisatin
CAS:<p>6,7-Dimethylisatin (6,7-dimethyl-1H-indole-2,3-dione) inhibits hGAT3 with IC50 of 108 μM. 6,7-Dimethylisatin also inhibits hBGT1, hGAT2.</p>Formula:C10H9NO2Purity:98.98%Color and Shape:SolidMolecular weight:175.18Roquefortine C
CAS:<p>Roquefortine C is a fungal cyclopeptide isolated from Penicillium roquefortii, activates P-gp and also inhibits P450-3A and other haemoproteins</p>Formula:C22H23N5O2Purity:98%Color and Shape:SolidMolecular weight:389.45(-)-(S)-Cibenzoline
CAS:<p>Cibenzoline, also known as Escibenzoline, is the S(+)-enantiomer of Cibenzoline and functions as an antiarrhythmic agent.</p>Formula:C18H18N2Color and Shape:SolidMolecular weight:262.35AVLX-125
CAS:<p>AVLX-125 (UCCB01-125), a potent inhibitor of PSD-95 and PDZ domains, exhibits a dissociation constant (Kd) of 10 nM. It is utilized in researching inflammatory pain [1] [2].</p>Formula:C62H104N10O29Color and Shape:SolidMolecular weight:1453.54S-Sulfo-L-cysteine sodium salt
CAS:<p>S-Sulfo-L-cysteine sodium salt shows a weak affinity for mGluR1α and mGluR5a at high concentrations and has potential antioxidant activity.</p>Formula:C3H6NNaO5S2Purity:99.88%Color and Shape:SolidMolecular weight:223.2Sulcardine 2HCl
CAS:<p>Sulcardine 2HCl is a multi-ion channel blocker that blocks the properties of hERG and hNav1.5 channels and can be used to study atrial fibrillation.</p>Formula:C24H35Cl2N3O4SPurity:99.33% - 99.76%Color and Shape:SoildMolecular weight:532.523AChE/Aβ-IN-1
<p>AChE/Aβ-IN-1 (compound 32) is a potent, orally active acetylcholinesterase (AChE) inhibitor with an IC50 of 86 nM and an NMDA receptor antagonist targeting the</p>Formula:C20H25BrN4Color and Shape:SolidMolecular weight:401.34Oleoyl Serotonin
CAS:<p>Oleoyl Serotonin is an antagonist of hTRPV1 with an IC50 of 2.57 μM.</p>Formula:C28H44N2O2Purity:99.88%Color and Shape:SolidMolecular weight:440.66URAT1 inhibitor 11
CAS:<p>URAT1 inhibitor11 (Compound 7) is a potent URAT1 inhibitor, exhibiting an IC50 of 0.18 μM. It effectively reduces uric acid levels in zebrafish with hyperuricemia induced by Potassium oxonate and Xanthinesodium salt.</p>Formula:C20H16F4N2O2Color and Shape:SolidMolecular weight:392.35(S)-PF-03716556
CAS:<p>(S)-PF-03716556 can be used as an acid pump inhibitor for the treatment of disease conditions mediated by acid pump inhibitory activity.</p>Formula:C22H26N4O3Purity:99.8% - 99.91%Color and Shape:SoildMolecular weight:394.47GYKI-47261 dihydrochloride
CAS:<p>GYKI-47261 dihydrochloride is an AMPA receptor antagonist and CYP2E1 inducer, demonstrating broad-spectrum anticonvulsant and neuroprotective activities.</p>Formula:C18H17Cl3N4Purity:98.32% - 99.14%Color and Shape:SolidMolecular weight:395.71Antidepressant agent 4
<p>Antidepressant agent 4: orally active, has antidepressant, anxiolytic, and nootropic effects.</p>Formula:C19H38ClN5O2SColor and Shape:SolidMolecular weight:436.06Astressin 2B
CAS:<p>CRF2 antagonist with IC50 of 1.3 nM; >500 nM for CRF1. Aids gastric emptying.</p>Formula:C183H307N49O53Purity:98%Color and Shape:SolidMolecular weight:4041.69Mambalgin-2
<p>Mambalgin-2 (Mamb-2), a venom peptide sourced from the African black mamba, acts as an inhibitor of acid-sensitive ion channels (ASICs).</p>Formula:C272H431N85O83S10Purity:98%Color and Shape:SolidMolecular weight:6540.5μ-Conotoxin SxIIIC
<p>μ-Conotoxin SxIIIC, an irreversible NaV channel inhibitor, is derived from Conus striolatus and is useful in researching neurological disorders, including</p>Formula:C90H142N42O27S6Purity:98%Color and Shape:SolidMolecular weight:2436.75δ-Buthitoxin-Hj2a
<p>δ-Buthitoxin-Hj2a, a potent scorpion-venom peptide, acts as a NaV1.1 agonist with an EC50 value of 32 nM and is employed in Dravet syndrome (DS) research [1].</p>Formula:C304H458N90O93S8Purity:98%Color and Shape:SolidMolecular weight:7117.96A 80915A
CAS:<p>A80915A: Semi-naphthoquinone antibiotic, blocks gastric (H(+)-K+)-ATPase; potency varies with enzyme conformation; K+ reduces binding rate.</p>Formula:C26H31Cl3O5Color and Shape:SolidMolecular weight:529.88Jingzhaotoxin III
CAS:<p>NaV1.5 channels blocker</p>Formula:C174H241N47O46S6Purity:98%Color and Shape:SolidMolecular weight:3919.47Ceratotoxin-2
CAS:<p>Ceratotoxin-2 (CcoTx2) is a voltage-gated sodium channel inhibitor, demonstrating half maximal inhibitory concentrations (IC50) of 8 nM for Na v 1.2/β 1 and 88</p>Formula:C177H260N52O49S6Purity:98%Color and Shape:SolidMolecular weight:4092.67
