Membrane Transporter/Ion Channel
Membrane transporter and ion channel inhibitors are compounds that block the function of proteins responsible for the transport of ions, nutrients, and other molecules across cell membranes. These inhibitors are crucial for studying the regulation of cellular homeostasis, signal transduction, and neurotransmission. Membrane transporter and ion channel inhibitors are also important in developing treatments for disorders such as epilepsy, cardiovascular diseases, and metabolic syndromes. At CymitQuimica, we provide a diverse selection of high-quality membrane transporter and ion channel inhibitors to support your research in physiology, neuroscience, and pharmacology.
Subcategories of "Membrane Transporter/Ion Channel"
- ABC(3 products)
- ATPase(99 products)
- Adiponectin receptor(5 products)
- CFTR(65 products)
- CGRP Receptor(54 products)
- Calcium Channel(546 products)
- Chloride channel(53 products)
- GABA Receptor(369 products)
- Monoamine Transporter(30 products)
- Monocarboxylate transporter(18 products)
- NKCC(2 products)
- NPC1L1(3 products)
- Na-K-Cl cotransporter(10 products)
- OAT(32 products)
- OCT(7 products)
- P-gp(55 products)
- Potassium Channel(283 products)
- Proton pump(41 products)
- SGLT(31 products)
- Sodium Channel(219 products)
- TRP/TRPV Channel(96 products)
Show 13 more subcategories
Found 2623 products of "Membrane Transporter/Ion Channel"
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CGP-78608
CAS:CGP-78608 is a glycine site-specific N-methyl-D-aspartate receptor antagonist prevents activation of the NMDA/NO/CGMP pathway by ammonia.Formula:C11H13BrN3O5PColor and Shape:SolidMolecular weight:378.12Zatebradine hydrochloride
CAS:Zatebradine hydrochloride (UL-FS-49CL) inhibits HCN channels (IC50: ~1.9 µM) blocking human HCN1-4 currents effectively.Formula:C26H37ClN2O5Purity:98.61%Color and Shape:SolidMolecular weight:493.04Ref: TM-T13387L
5mg50.00€10mg73.00€25mg146.00€50mg268.00€100mg411.00€500mgTo inquire1mL*10mM (DMSO)51.00€Etbicyphat
CAS:Etbicyphat: potent GABA(A) antagonist, induces epileptiform activity, binds to GABA/benzodiazepine receptors.Formula:C6H11O4PColor and Shape:SolidMolecular weight:178.12TMB 8 (hydrochloride)
CAS:TMB 8 blocks nAChRs (IC50: 390-480 nM), reduces Ca2+ in muscles, hinders rabbit aorta contraction at 50 μM, and inhibits PKC dose-dependently.Formula:C22H38ClNO5Color and Shape:White SolidMolecular weight:431.99P-gp inhibitor 4
CAS:P-gp inhibitor 4 is a selective P-glycoprotein modulator with an EC 50 of 94 nM.Formula:C38H38N2O8S2Color and Shape:SolidMolecular weight:714.85UT-B-IN-1
CAS:UT-B-IN-1: reversible UT-B inhibitor, IC50: 10 nM (human), 25 nM (mouse), low toxicity, diuretic research tool.Formula:C20H17N5O2S3Color and Shape:SolidMolecular weight:455.58Procyclidine
CAS:Procyclidine is an anticholinergic, muscarinic and NMDA antagonist used in Parkinson's and psychiatric disorder studies.Formula:C19H29NOColor and Shape:SolidMolecular weight:287.44RA-2
CAS:RA-2 is a pan-negative-gating modulator of KCa2/3 channels that acts by inhibiting EDH-type relaxation in coronary arteries.Formula:C22H16F2O6Color and Shape:SolidMolecular weight:414.364,9-Anhydrotetrodotoxin
CAS:4,9-anhydro-TTX blocks Nav1.6 channels (IC50=7.8 nM); has varying IC50 for Nav1.2-Nav1.8.Formula:C11H15N3O7Color and Shape:SolidMolecular weight:301.25OptoBI-1
CAS:OptoBI-1 是一种光敏分子，是光致变色的TRPC3激动剂，可用作控制神经元放电的光药理学工具。Formula:C32H37N5O2Color and Shape:SoildMolecular weight:523.67GSK-5503A
CAS:GSK-5503A is a novel channel blocker of CRAC.Formula:C23H17F2N3O2Purity:98%Color and Shape:SolidMolecular weight:405.4MCC-134
CAS:MCC-134 is an inverse agonist for the pancreatic-type ATP-sensitive K(+) channel. It also used as a vascular relaxing agent.Formula:C16H17N3OSColor and Shape:SolidMolecular weight:299.39(Rac)-MEM 1003
CAS:MEM-1003, a calcium channel blocker, is used potentially for the treatment of bipolar disorders.Formula:C22H25ClN2O5Color and Shape:SolidMolecular weight:432.9Lercanidipine. (R)-
CAS:(R)-Lercanidipine enantiomer: antihypertensive, blocks L-type Ca2+ channels, dilates blood vessels.Formula:C36H41N3O6Color and Shape:SolidMolecular weight:611.73D-AP4
CAS:broad spectrum excitatory amino acid receptor antagonistFormula:C4H10NO5PPurity:98%Color and Shape:White PowderMolecular weight:183.1TPA-023B
CAS:TPA-023B: oral GABAA α2/α3 agonist (Kis: 0.73/2 nM), α1 antagonist (Ki: 1.8 nM), non-sedating anxiolytic.Formula:C21H15F2N5OPurity:98%Color and Shape:SolidMolecular weight:391.37L-701252
CAS:L-701252, a potent glycine site NMDA receptor antagonist, exhibits an inhibition concentration (IC50) of 420 nM.Formula:C13H10ClNO3Purity:97.7%Color and Shape:White Crystalline SolidMolecular weight:263.68PA1 2HCl
CAS:PA1 2HCl is a blocker of photoswitchable epithelial sodium channel (ENaC).Formula:C18H16ClN9OColor and Shape:SolidMolecular weight:409.83PPPA
CAS:PPPA is a NMDA receptor antagonist.Formula:C9H18NO5PPurity:98%Color and Shape:SolidMolecular weight:251.22P-gp inhibitor 1
CAS:P-gp inhibitor 1 inhibits reversing P-glycoprotein-mediated multidrug resistance with an EC50 of 57.9 nM (K562/A02 cells).Formula:C32H31N5O2Purity:98.65%Color and Shape:SolidMolecular weight:517.62Ref: TM-T12341
5mg50.00€10mg84.00€25mg150.00€50mg219.00€100mg304.00€200mg419.00€1mL*10mM (DMSO)58.00€LY 233536
CAS:LY 233536 is a novel, competitive antagonist of NMDA receptor.Formula:C12H19N5O2Purity:98%Color and Shape:SolidMolecular weight:265.31Cyclic ADP-ribose
CAS:cADPR, made from NAD+, boosts calcium in cells via Ryanodine receptors and TRPM2 channels.Formula:C15H21N5O13P2Purity:98%Color and Shape:Lyophilized PowderMolecular weight:541.3PF05020182
CAS:PF05020182, a Kv7.2/4 opener, prevents convulsions in MES tests, supporting its potential use in refractory epilepsy treatment.Formula:C18H30N4O4Color and Shape:SolidMolecular weight:366.46Cgp 55802A
CAS:CGP 55802A is a novel photoaffinity ligand for in-situ labeling of NMDA receptors.Formula:C18H24IN5NaO7PColor and Shape:SolidMolecular weight:603.286UMB68 sodium
CAS:UMB-68 is a GHB receptor ligand with no affinity (IC(50) >100 microM) at GABA(A) or GABA(B) receptors.Formula:C6H12NaO3Color and Shape:SolidMolecular weight:155.1495'-Iodoresiniferatoxin
CAS:TRPV1 (VR1) receptor antagonistFormula:C37H39IO9Purity:98%Color and Shape:SolidMolecular weight:754.6(S)-AMPA
CAS:(S)-AMPA is an active isomer of AMPA and a selective agonist of AMPA.Formula:C7H10N2O4Color and Shape:SolidMolecular weight:186.17Bifenazate
CAS:Bifenazate is a positive allosteric modulator of GABA receptor. Bifenazate is an acaricide that controls 100% of mites at a concentration of 25 ppm.Formula:C17H20N2O3Purity:99.62%Color and Shape:Solid CrystallineMolecular weight:300.35Cryosim-3
CAS:Cryosim-3 is a water-soluble, potent, and selective TRPM8 receptor agonist.Formula:C15H33OPColor and Shape:SolidMolecular weight:260.4S-8921
CAS:S-8921 is an inhibitor of ileal Na+/bile acid cotransporter.Formula:C30H36O9Purity:98%Color and Shape:SolidMolecular weight:540.6SKF-97574 HCl
CAS:SKF-97574 is proton pump inhibitor.Formula:C22H25ClN2O3Purity:98%Color and Shape:SolidMolecular weight:400.9L-AP5
CAS:L-AP5 is a NMDA antagonist.Formula:C5H12NO5PPurity:98%Color and Shape:SolidMolecular weight:197.13BK 129
CAS:BK 129 is a local anesthetic with relaxant properties. BK 129 inhibits Ca2+ entry into the smooth muscle cell and Ca2+ release from sarcoplasmic reticulum.Formula:C22H36N2O4Purity:98%Color and Shape:SolidMolecular weight:392.53H100
CAS:H100 inhibits Cl- transport, mildly affects NaK2Cl cotransporter and Band 3 anion exchanger, not KCl cotransporter.Formula:C18H16N2O6SPurity:98%Color and Shape:SolidMolecular weight:388.4Palonidipine HCl
CAS:Palonidipine HCl is a calcium channel antagonist potentially for the treatment of angina pectoris and hypertension.Formula:C29H35ClFN3O6Color and Shape:SolidMolecular weight:576.06KMUP-4
CAS:Kmup-4 is an enhancer of cGMP activity and an aortic smooth muscle relaxant.Formula:C19H23N7O4Color and Shape:SolidMolecular weight:413.43GX-585
CAS:GX-585 is a novel potent inhibitor of NaV1.7 and highly selective against NaV1.5, having limited selectivity against NaV1.1 and NaV1.2.Formula:C24H25Cl2FN4O3SPurity:99.02% - 99.03%Color and Shape:SolidMolecular weight:539.45BMS-919373
CAS:BMS-919373 is a potassium channel Kv1.5 (KCNA5) inhibitor for atrial fibrillation and acute coronary syndrome.Formula:C25H20N6O2SPurity:98.51% - 99.01%Color and Shape:SolidMolecular weight:468.53Ref: TM-T30544
1mg234.00€5mg572.00€10mg803.00€25mg1,189.00€50mg1,603.00€100mg2,152.00€1mL*10mM (DMSO)622.00€JNJ-54166060
CAS:JNJ-54166060 is a potent and selective antagonist of P2X7 receptor, with IC 50 s of 4/115/72 nM for human/rat/mouse P2X7 receptor, respectively [1].Formula:C20H15ClF4N4OColor and Shape:SolidMolecular weight:438.81A1899
CAS:A1899 is a effective and selective TASK-1 and TASK-3 antagonist.Formula:C30H26F2N2O3Purity:98%Color and Shape:SolidMolecular weight:500.54DDO-02005 free base
CAS:DDO-02005 is a potent Kv1.5 inhibitor with IC50 of 0.72μM, showing strong anti-arrhythmic and anti-AF effects in rat models.Formula:C21H25N3O2Color and Shape:SolidMolecular weight:351.44Eltanexor Z-isomer
CAS:Eltanexor Z-isomer, less active than KPT-8602, inhibits Z138, MM1S, and 3T3 cells with IC50s: 100 nM-50 μM, <100 nM, >30 μM.Formula:C17H10F6N6OColor and Shape:SolidMolecular weight:428.293-Chlorodiphenylamine
CAS:3-Cl-DPA, a cardiac troponin activator, acts by a mechanism distinct from bepridil or TFP.Formula:C12H10ClNColor and Shape:SolidMolecular weight:203.67NS-8
CAS:NS-8, a pyrrole, activates Ca2+-sensitive K+ channels, reducing urinary frequency by inhibiting pelvic nerve activity.Formula:C12H10FN3Color and Shape:SolidMolecular weight:215.23NHE3-IN-3
CAS:NHE3-IN-3 inhibits human/rat NHE3 with pIC50s 6.2/6.6; 98% oral bioavailability in rats.Formula:C16H16Cl2N2O2SColor and Shape:SolidMolecular weight:371.28UBP141
CAS:UBP141 is a antagonist of N-methyl-D-aspartate (NMDA) receptor.Formula:C21H18N2O5Purity:98%Color and Shape:SolidMolecular weight:378.38JNJ-56022486
CAS:JNJ-56022486 is a selective TARP γ‑8 AMPA receptor modulator.Formula:C15H10ClN3OPurity:98%Color and Shape:SolidMolecular weight:283.71(R)-Olacaftor
CAS:(R)-Olacaftor (VX-440) is a CFTR modulator with promise for researching cystic fibrosis.Formula:C29H34FN3O4SColor and Shape:SolidMolecular weight:539.66Aprindine hydrochloride
CAS:Aprindine HCl, a Class 1b antiarrhythmic, treats heart arrhythmias, outperforming digoxin in delaying atrial fibrillation. It's effective orally.Formula:C22H31ClN2Color and Shape:SolidMolecular weight:358.95Remacemide
CAS:Remacemide is a low-affinity NMDA antagonist with sodium channel blocking properties.Formula:C17H20N2OColor and Shape:SolidMolecular weight:268.35
