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Membrane Transporter/Ion Channel

Membrane Transporter/Ion Channel

Membrane transporter and ion channel inhibitors are compounds that block the function of proteins responsible for the transport of ions, nutrients, and other molecules across cell membranes. These inhibitors are crucial for studying the regulation of cellular homeostasis, signal transduction, and neurotransmission. Membrane transporter and ion channel inhibitors are also important in developing treatments for disorders such as epilepsy, cardiovascular diseases, and metabolic syndromes. At CymitQuimica, we provide a diverse selection of high-quality membrane transporter and ion channel inhibitors to support your research in physiology, neuroscience, and pharmacology.

Subcategories of "Membrane Transporter/Ion Channel"

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Found 2402 products of "Membrane Transporter/Ion Channel"

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  • Bendroflumethiazide
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    Bendroflumethiazide

    CAS:
    <p>Bendroflumethiazide (Naturetin) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)</p>
    Formula:C15H14F3N3O4S2
    Purity:98% - >99.99%
    Color and Shape:Crystals From Dioxane Solid
    Molecular weight:421.41

    Ref: TM-T1204

  • TP-050
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    TP-050

    CAS:
    <p>TP-050: potent, selective NMDAR agonist, EC50 0.51 µM (GluN2A), 9.6 µM (GluN2D), BBB permeable, boosts hippocampal LTP.</p>
    Formula:C16H15ClF2N6O
    Color and Shape:Solid
    Molecular weight:380.78

    Ref: TM-T73491

  • Volixibat
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    Volixibat

    CAS:
    <p>Volixibat, a selective inhibitor of the bile acid transporter, may treat non-alcoholic steatohepatitis.</p>
    Formula:C38H51N3O12S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:805.95

    Ref: TM-T17236

  • P2X4 antagonist-4
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    P2X4 antagonist-4

    P2X4 antagonist-4 (compound 64) is a potent P2X4R antagonist with an IC50 value of 8 µM. It can inhibit ATP-induced activation of the NLRP3 inflammasome and the subsequent release of IL-1β.
    Formula:C27H22FN3O4S
    Color and Shape:Solid
    Molecular weight:503.545

    Ref: TM-T204441

  • 3-Aminopropylphosphonic Acid
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    3-Aminopropylphosphonic Acid

    CAS:
    <p>3-aminopropylphosphonic acid (3-APPA) is a phosphonic analog of GABA that acts as a partial agonist of GABAB receptors (IC50 = 1.5 μM in a radioligand binding</p>
    Formula:C3H10NO3P
    Purity:99.84%
    Color and Shape:Light Yellow Liquid
    Molecular weight:139.09

    Ref: TM-T38205

  • Hyp9
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    Hyp9

    CAS:
    <p>Hyp9, a specific agonist for the transient receptor potential canonical 6 (TRPC6) channel, is utilized in spinal cord injury (SCI) research [1].</p>
    Formula:C18H26O5
    Color and Shape:Solid
    Molecular weight:322.40

    Ref: TM-T75550

  • Neurotransmitter Receptor Compound Library
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    Neurotransmitter Receptor Compound Library

    <p>A unique collection of 1513 neurotransmitter receptor compounds, can be used for HTS and HCS screening；</p>
    Color and Shape:Odour Solid

    Ref: TM-L2610

  • 17(S)-HETE
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    17(S)-HETE

    CAS:
    <p>Arachidonic acid and its CYP450 metabolite, 17(S)-HETE, regulate kidney electrolytes; 17(S)-HETE reduces proximal tubule ATPase activity by 70% at 2 μM.</p>
    Formula:C20H32O3
    Color and Shape:Solid
    Molecular weight:320.473

    Ref: TM-T35849

  • Trans (2,3)-Dihydrotetrabenazine
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    Trans (2,3)-Dihydrotetrabenazine

    CAS:
    <p>Trans (2,3)-Dihydrotetrabenazine is a Tetrabenazine metabolite, shows inhibition activity on vesicular monoamine transporter (VMAT2).</p>
    Formula:C19H29NO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:319.44

    Ref: TM-T12190

  • SLC26A3-IN-2
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    SLC26A3-IN-2

    CAS:
    <p>Vilobelimab (CaCP-29) is a human-mouse chimeric IgG antibody targeting human complement component 5a, a C5a inhibitor that inhibits neutrophil activation.</p>
    Formula:C19H13ClN2O2S
    Purity:99.86%
    Color and Shape:Solid
    Molecular weight:368.84

    Ref: TM-T74815

  • CymitQuimica logo
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    Chlorotoxin TFA

    <p>Chlorotoxin TFA, a scorpion venom peptide, blocks chloride channels and has anti-cancer properties.</p>
    Formula:C160H250F3N53O49S11
    Color and Shape:Solid
    Molecular weight:4109.74

    Ref: TM-T75722

  • BeKm-1
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    BeKm-1

    CAS:
    Potent, selective hERG (KV11.1) blocker; doesn't affect 14 other K+ channels; extends QTc in rabbit heart dose-dependently.
    Formula:C174H261N51O52S6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:4091.65

    Ref: TM-TP2072

  • CymitQuimica logo
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    Idactamab

    CAS:
    <p>Idactamab (INT-001) is a monoclonal antibody to the human amino acid transport protein ASCT2.</p>
    Purity:> 95%
    Color and Shape:Liquid
    Molecular weight:146.2 kDa

    Ref: TM-T77385

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    Huwentoxin I

    CAS:
    <p>Huwentoxin I (HWTX-I) is a peptide toxin that targets and inhibits both voltage-gated sodium channels and N-type calcium channels.</p>
    Formula:C161H246N48O44S6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3750.36

    Ref: TM-T80185

  • Sulcardine 2HCl
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    Sulcardine 2HCl

    CAS:
    <p>Sulcardine 2HCl is a multi-ion channel blocker that blocks the properties of hERG and hNav1.5 channels and can be used to study atrial fibrillation.</p>
    Formula:C24H35Cl2N3O4S
    Purity:99.33% - 99.76%
    Color and Shape:Soild
    Molecular weight:532.523

    Ref: TM-T83979

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    Crofelemer

    CAS:
    <p>Crofelemer (Provir) is an orally active antidiarrheal agent. It targets the cystic fibrosis transmembrane conductance regulator (CFTR) and calcium-activated chloride channels (CACC), which are responsible for chloride and fluid secretion in the gastrointestinal tract. Crofelemer is applicable for research in diarrhea-related conditions.</p>
    Color and Shape:Solid

    Ref: TM-T205474

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    Anticonvulsant agent 9

    <p>Anticonvulsant agent 9 (compound 4f) is an activator of the α1β2γ2GABA_A receptor, with an EC50 value of 1.24 μM. It inhibits the inactivation of Nav1.2 channels and exhibits significant anticonvulsant activity.</p>
    Formula:C22H24N4O2
    Color and Shape:Solid
    Molecular weight:376.45

    Ref: TM-T205256

  • Cevadine
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    Cevadine

    <p>Cevadine is a natural product that can be used as a reference standard.</p>
    Formula:C32H49NO9
    Color and Shape:Solid
    Molecular weight:591.742

    Ref: TM-T124525

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    Analgesic/antidepressant agent-1

    <p>Analgesic/antidepressant agent-1 (Compound k1) is an orally active N-acetylamino chloro ketone derivative capable of crossing the blood-brain barrier. It exhibits high affinity for NMDA receptors and demonstrates analgesic, anti-inflammatory, and antidepressant properties, with low psychotomimetic activity.</p>
    Formula:C22H25ClN2O2
    Color and Shape:Solid
    Molecular weight:384.9

    Ref: TM-T205604

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    Ebio3

    <p>Ebio3 is a selective potassium ion channel (KCNQ2) inhibitor with an IC50 of 1.2 nM. It binds to the KCNQ2 channel via its hydrophobic tail, causing the inward movement of the S6 helix, which results in the closure of the internal gate. The inhibitory effect of Ebio3 is equally effective on pathogenic KCNQ2 mutants, such as R75C and I238L, reducing their outward current by approximately 80%. Ebio3 holds potential for research in neurological disorders like epilepsy.</p>
    Formula:C19H23F2N3O2
    Color and Shape:Solid
    Molecular weight:363.4

    Ref: TM-T205242