Membrane Transporter/Ion Channel
Membrane transporter and ion channel inhibitors are compounds that block the function of proteins responsible for the transport of ions, nutrients, and other molecules across cell membranes. These inhibitors are crucial for studying the regulation of cellular homeostasis, signal transduction, and neurotransmission. Membrane transporter and ion channel inhibitors are also important in developing treatments for disorders such as epilepsy, cardiovascular diseases, and metabolic syndromes. At CymitQuimica, we provide a diverse selection of high-quality membrane transporter and ion channel inhibitors to support your research in physiology, neuroscience, and pharmacology.
Subcategories of "Membrane Transporter/Ion Channel"
- ABC(3 products)
- ATPase(101 products)
- Adiponectin receptor(5 products)
- CFTR(65 products)
- CGRP Receptor(54 products)
- Calcium Channel(541 products)
- Chloride channel(53 products)
- GABA Receptor(365 products)
- Monoamine Transporter(30 products)
- Monocarboxylate transporter(18 products)
- NKCC(2 products)
- NPC1L1(3 products)
- Na-K-Cl cotransporter(10 products)
- OAT(32 products)
- OCT(7 products)
- P-gp(54 products)
- Potassium Channel(280 products)
- Proton pump(42 products)
- SGLT(31 products)
- Sodium Channel(209 products)
- TRP/TRPV Channel(95 products)
Show 13 more subcategories
Found 2512 products of "Membrane Transporter/Ion Channel"
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P-gp inhibitor 2
CAS:Potent P-gp inhibitor 2 reverses Doxorubicin resistance in colorectal carcinoma cells with IC50 of 0.22 µM.Formula:C29H26N2O6Color and Shape:SolidMolecular weight:498.53KV1.3-IN-2
CAS:<p>KV1.3-IN-2 (Compound I) selectively inhibits the kv1.3 potassium channel without affecting the hERG channel. It is applicable in research related to immune-associated diseases such as psoriasis, rheumatoid arthritis, and systemic lupus erythematosus.</p>Formula:C16H23ClN2O4Color and Shape:SolidMolecular weight:342.818Dehydelone
CAS:Dehydelone(KOS-1584, R-1645, SK-10088) is a microtubule stabilizer that may be used in the treatment of non-small cell lung cancer.Formula:C27H39NO5SColor and Shape:SolidMolecular weight:489.67GABAA receptor agonist 2
Compound 4c, a potent GABAA agonist with anti-depressive effects in mouse FST/TST, shows promise in depression research.Formula:C22H36O5Color and Shape:SolidMolecular weight:380.52P-gp modulator 2
P-gp modulator 2 (Compound 27) is a potent competitive and metabotropic P-glycoprotein (P-gp) modulator.Formula:C22H20BrN3O4Color and Shape:SolidMolecular weight:470.32Opakalim
CAS:<p>Opakalim is an activator of potassium channels (potassium channel) and exhibits anticonvulsant activity.</p>Formula:C18H22F2N4OColor and Shape:SolidMolecular weight:348.39hURAT1 inhibitor 2
CAS:hURAT1 inhibitor 2 (Compound 5) is an inhibitor of hURAT1 (uric acid transporter 1, SLC22A12) with an IC50 of 18 nM. It also exhibits some inhibitory activity against OATP1B1, with an IC50 of 0.73 μM. hURAT1 inhibitor 2 can be used in research related to hyperuricemia, gout, and other diseases associated with abnormal uric acid metabolism.Formula:C17H11Br2FO3Color and Shape:SolidMolecular weight:442.074TRPC4/5-IN-1
TRPC4/5-IN-1, a TRPC5/4 inhibitor with IC50s 0.54 μM/2.06 μM, targets skin inflammation and proteinuric kidney diseases.Formula:C21H21N3OColor and Shape:SolidMolecular weight:331.41Probenecid sodium
CAS:<p>Probenecid sodium is the sodium salt of Probenecid, a potent and selective agonist of transient receptor potential vanilloid 2 (TRPV2) channels. Additionally, Probenecid acts as an inhibitor of pannexin 1 channels.</p>Formula:C13H18NNaO4SColor and Shape:SolidMolecular weight:307.341(RS)-AMPA monohydrate
CAS:(RS)-AMPA monohydrate, potent glutamate analogue, selectively activates L-glutamic acid without affecting kainic acid or NMDA receptors.Formula:C7H12N2O5Color and Shape:SolidMolecular weight:204.1828-Prenylchrysin
CAS:<p>8-Prenylchrysin is a C8-isopentenyl flavonoid compound. It acts as an inhibitor of P-glycoprotein (P-gp) and can be utilized in cancer research.</p>Formula:C20H18O4Color and Shape:SolidMolecular weight:322.354INCB-056868
CAS:INCB-056868 is the metabolite M11 of Epacadostat. It serves as a substrate for BCRP and holds potential for use in the study of metabolic diseases.Formula:C11H13BrFN7O3SColor and Shape:SolidMolecular weight:422.23Unoprostone isopropyl
CAS:Unoprostone isopropyl, a prostanoid and synthetic docosanoid, is approved for the treatment of ocular hypertension and open-angle glaucoma.Formula:C25H44O5Purity:98%Color and Shape:SolidMolecular weight:424.61NSC73306
CAS:NSC73306 is a thiosemicarbazone known for its role as a cell-permeable agent, exhibiting increased toxicity towards cells expressing p-glycoprotein.Formula:C16H14N4O2SColor and Shape:SolidMolecular weight:326.373DAD dichloride
DAD dichloride is a 3rd-gen photoelectric switch, blocks K+ channels, and helps in visual function research.Formula:C26H42Cl2N6OColor and Shape:SolidMolecular weight:525.56WS-898
<p>WS-898 boosts paclitaxel efficacy in resistant cells by inhibiting ABCB1; IC50: SW620/Ad300 - 5.0 nM, KB-C2 - 3.67 nM, HEK293/ABCB1 - 3.68 nM.</p>Formula:C33H25N7OSColor and Shape:SolidMolecular weight:567.66GABAA receptor agonist 1
Compound 3e, a potent GABAA agonist, targets GABA sites and has potential anti-depressive effects in mice.Formula:C20H30O3Color and Shape:SolidMolecular weight:318.45MRS4738
MRS4738 is a potent antagonist with high affinity for the P2Y14R receptor. It demonstrates in vivo anti-hyperallodynic and antiasthmatic activity [1].Formula:C30H24F3NO2Color and Shape:SolidMolecular weight:487.51ABCA1 inducer 2
CAS:ABCA1 inducer 2 is a non-lipogenic inducer of ABCA1. It increases the expression of ABCA1 by targeting the LXR pathway, thereby reducing lipid accumulation induced by ox-LDL and inhibiting foam cell formation. ABCA1 inducer 2 holds potential as an anti-atherosclerotic agent.Formula:C16H11BrN2OColor and Shape:SolidMolecular weight:327.175pan-HCN-IN-1
CAS:Pan-HCN-IN-1 (Compound J&J12e) is an inhibitor of the hyperpolarization-activated and cyclic-nucleotide-gated 1 (HCN1) ion channel, with an IC50 of 58 nM. Pan-HCN-IN-1 reduces the voltage sag response and enhances EPSP summation in ex vivo rat brain slices [1].Formula:C23H37N3O2Color and Shape:SolidMolecular weight:387.56
